Title: Hotels in Southeast Missouri - Best Southeast Missouri Hotels from £47 - Fully Refundable Options - Expedia.co.uk

 

[Southeast Missouri Travel Guide](https://expedia.co.uk/Southeast-Missouri.dx6058763)[Holiday Rentals in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Holiday-Rentals.d6058763.Travel-Guide-HolidayRentals)[Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks)

![150th anniversary of the historic French fort. ](https://images.trvl-media.com/place/148078/1ef720df-0786-4e45-8a4f-890d982b757b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by JG Morris

# Find hotels in Southeast Missouri, MO from £47

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## Go beyond your typical stay in Southeast Missouri

Hot tub

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&amenities=HOT_TUB)

Farm

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&lodging=AGRITOURISM)

Cabin

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&lodging=CABIN)

Pool

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&amenities=POOL)

Pet friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&amenities=PETS)

Family friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&travelerType=family_friendly)

Apart­ment

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&lodging=APARTMENT)

Cottage

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&lodging=COTTAGE)

Waterpark

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-11-15&d1=2025-11-15&endDate=2025-11-17&d2=2025-11-17&amenities=WATER_PARK)

## Check prices for these dates

Tonight

[1 Nov - 2 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[2 Nov - 3 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top 10 Southeast Missouri hotels and places to stay

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/13275a81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/8003191a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/35f08a54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Farmstead Hotel

Caruthersville

8.8/10

Excellent

(437)

"Excellent hotel. Very clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Don

£74

includes taxes & fees

2 Nov - 3 Nov

[](https://www.expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Perryville by IHG

Perryville

9.2/10

Wonderful

(524)

"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christina

£83

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1009)

"Great service! Definitely will stay there again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

£72

includes taxes & fees

6 Nov - 7 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(644)

"Stayed on our way south for vacation. It was a clean nice place to stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joel

£69

includes taxes & fees

4 Nov - 5 Nov

[](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

Cape Girardeau

9.0/10

Wonderful

(1004)

"Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

£60

includes taxes & fees

2 Nov - 3 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/720261dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/2d71c942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/77434452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/6d872386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

9.4/10

Exceptional

(689)

"Love staying at the holiday inn ans suites "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amber

£110

includes taxes & fees

16 Nov - 17 Nov

[](https://www.expedia.co.uk/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d234bb55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Refrigerator | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d7244881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/5d1ea140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Farmington

Farmington

8.0/10

Very good

(599)

"Clean, friendly staff, quiet"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stacy

£44

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1001)

"Great place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

£81

includes taxes & fees

14 Nov - 15 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/f46408d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/a5281c8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/b4e45ee9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Hayti Caruthersville

Hayti

9.4/10

Exceptional

(1000)

"Room was beautiful, clean, food was great, and staff was absolutely excellent."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anidra

£81

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

Cape Girardeau

9.4/10

Exceptional

(1003)

"Excellent place. Really friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alex

£77

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s play area – outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/db5aadc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/136440e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Echo Bluff State Park

Eminence

9.4/10

Exceptional

(211)

"Beautiful location & very friendly staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Becky

£118

includes taxes & fees

4 Nov - 5 Nov

[](https://www.expedia.co.uk/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information)

![Standard Room, 1 King Bed | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/2cf60fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/04ce172c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/05c7ee11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/79923507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Potosi

Potosi

7.0/10

Good

(372)

"I like how convenient everything was mangers were awesome All my needs were met and I look forward to visiting there again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shirley

£46

includes taxes & fees

2 Nov - 3 Nov

[](https://www.expedia.co.uk/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Building design](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/f4d876e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking | 1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/23ae42af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/7e9b49ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

8.0/10

Very good

(1006)

"Great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gregory

£47

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1004)

"Always enjoy our stay. Staff is very friendly, especially at breakfast! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

£60

includes taxes & fees

6 Nov - 7 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Perryville

Perryville

8.4/10

Very good

(923)

"We had a nice stay and they were pet friendly! The front desk staff was very nice and welcoming. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacquelin

£58

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/219ce8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/96723311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/540bf915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/e3ed601e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Festus

Festus

6.8/10

(906)

"Room dirty, mirror cracked all the way down, shelf for towels hanging by one arm so no place for towels, stinky, pool to cold to get in and dirty."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

£70

additional charges may apply

4 Nov - 5 Nov

[](https://www.expedia.co.uk/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

Sikeston

9.4/10

Exceptional

(1001)

"Great staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Troy

£82

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Standard Double Room, 2 Queen Beds, Transfer Shower | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/690c1aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/c98026e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/16ab8462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/fba2b92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Century Casino & Hotel Caruthersville

Caruthersville

8.4/10

Very good

(84)

"Wonderful stay!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Miguel

£103

includes taxes & fees

2 Nov - 3 Nov

[](https://www.expedia.co.uk/Caruthersville-Hotels-Century-Casino-Hotel-Caruthersville.h111402094.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

8.8/10

Excellent

(416)

"Nice property and friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nancy

£84

includes taxes & fees

9 Nov - 10 Nov

[](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Riverview Two Queen Room | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Riverview

Cape Girardeau

9.4/10

Exceptional

(443)

"Location was perfect for family weekend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelly

£77

includes taxes & fees

4 Nov - 5 Nov

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16&regionId=6058763&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:**14 Nov - 16 Nov**

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/14339969.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Tiny Houses of French Village

French Village

**10/10**Exceptional (3 reviews)

9% off

£433

for 2 nights, 1 home

£217 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=83516509&adults=2)

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Echo Bluff State Park

Eminence

**9.4/10**Exceptional (211 reviews)

5% off

£289

for 2 nights, 1 room

£144 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=15487684&adults=2)

![Children’s play area – outdoor](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/e8909449.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Honeysuckle Inn - Mountain View

Mountain View

**8.6/10**Excellent (323 reviews)

15% off

£170

for 2 nights, 1 room

£85 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=42093410&adults=2)

![Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Rockwood Inn

Cape Girardeau

**10/10**Exceptional (16 reviews)

17% off

£285

for 2 nights, 1 room

£142 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=105486893&adults=2)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Riverview

Cape Girardeau

**9.4/10**Exceptional (443 reviews)

15% off

£201

for 2 nights, 1 room

£100 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=105081384&adults=2)

![BBQ/picnic Area](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/708e4b63.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Current River Inn

Van Buren

**8.2/10**Very good (162 reviews)

10% off

£152

for 2 nights, 1 room

£76 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=47039515&adults=2)

![Deluxe Double Room | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

VIP Access

### EC Reed's Mercantile and Hotel

Marble Hill

**9.6/10**Exceptional (80 reviews)

10% off

£192

for 2 nights, 1 room

£96 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=74660768&adults=2)

![Standard Double Room, 2 Queen Beds, Transfer Shower | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/690c1aa2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Century Casino & Hotel Caruthersville

Caruthersville

**8.4/10**Very good (84 reviews)

12% off

£206

for 2 nights, 1 room

£103 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=111402094&adults=2)

![Shared kitchen](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/66a0aee5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Arcadia Academy

Arcadia

**9.8/10**Exceptional (10 reviews)

13% off

£195

for 2 nights, 1 room

£98 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=112360980&adults=2)

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Farmstead Hotel

Caruthersville

**8.8/10**Excellent (437 reviews)

10% off

£148

for 2 nights, 1 room

£74 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=89303450&adults=2)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

**8.8/10**Excellent (644 reviews)

15% off

£138

for 2 nights, 1 room

£69 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=53348099&adults=2)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/13000000/12590000/12582100/12582009/57db158c.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Shepherd Mountain Inn

Ironton

**9.4/10**Exceptional (302 reviews)

10% off

£205

for 2 nights, 1 room

£102 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=12582009&adults=2)

![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### New Orleans Inn Portageville

Portageville

**8.0/10**Very good (714 reviews)

10% off

£118

for 2 nights, 1 room

£59 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-14&endDate=2025-11-16&selected=38979739&adults=2)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)

## Stay near popular Central United States attractions

[](https://www.expedia.co.uk/Elephant-Rocks-State-Park-Hotels.0-l553248621532648464-0.Travel-Guide-Filter-Hotels)

![A huge granite boulder located in Elephant Rocks State Park](https://images.trvl-media.com/place/6058764/b46f1ef8-a151-4a6d-a0ba-117f21235d8d.jpg)

Photo by Pat Long

### Elephant Rocks State Park

4.8/5 (52 reviews)

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648464)

[](https://www.expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels)

![Panorama of Academic Hall, Southeast Missouri State University ](https://images.trvl-media.com/place/553248621554122994/3bc9a5e0-c92b-4ca4-b94a-564376156913.jpg)

### Southeast Missouri State University

4.4/5 (137 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621554122994)

[](https://www.expedia.co.uk/Lake-Wappapello-Hotels.0-l553248621532648460-0.Travel-Guide-Filter-Hotels)

![Sunrise from the duck blind. ](https://images.trvl-media.com/place/183505/9493e565-66da-46c4-8222-30a8f5da22bb.jpg)

Photo by JG Morris

### Lake Wappapello

4.3/5 (40 reviews)

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648460)

[](https://www.expedia.co.uk/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels)

### Century Casino Caruthersville

3.2/5 (31 reviews)

Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532655201)

[](https://www.expedia.co.uk/Current-River-State-Park-Hotels.0-l553248621532648450-0.Travel-Guide-Filter-Hotels)

### Current River State Park

4.6/5 (15 reviews)

Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648450)

[](https://www.expedia.co.uk/Rocky-Falls-Hotels.0-l553248621532648456-0.Travel-Guide-Filter-Hotels)

### Rocky Falls

4.8/5 (4 reviews)

Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648456)

## Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

[See all hotels in Southeast Missouri](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16&adults=2&regionId=6058763)

![150th anniversary of the historic French fort. ](https://images.trvl-media.com/place/148078/1ef720df-0786-4e45-8a4f-890d982b757b.jpg?impolicy=fcrop&w=900&h=598&p=1&q=high)

Photo by JG Morris

## Top Southeast Missouri Hotel Reviews

![The Farmstead Hotel](//images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg)

### The Farmstead Hotel

10/10 Excellent

"Clean, quiet and friendly staff. "

[](https://expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"Very nice!"

[](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Beds were comfortable and good breakfast"

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"It was a great place to stay. It was convenient to seceral restaurants!"

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg)

### Tru By Hilton Cape Girardeau

10/10 Excellent

"It was a nice stay"

[](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Enjoyed the evening meal. Children enjoyed the hotdogs and nachos. Everything was great!"

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg)

### Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Amazing…just finished a 90 mile bike ride into the wind and was looking forward to a little nicer hotel with a hot tub. Awesome room, free drinks, free dinner, great breakfast…and the hot tub. Employees were awesome too. No Drury inns where I live but I will always look for them when I travel"

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg)

### Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent

"Simply the most friendly staff ever. There was a very minor computer glitch at check and they must have apologized three or four times. The hotel is in a great location, our rooms were very clean, and they were a good value. "

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg)

### Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent

"Yes everything was good"

[](https://expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

## More cheap stays in Southeast Missouri

![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St, Farmington, MO

£47

9 Nov - 10 Nov

includes taxes & fees

8/10 Very Good! (1,010 reviews)

[](https://expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr, Sikeston, MO

£55

4 Nov - 5 Nov

includes taxes & fees

7.2/10 Good! (1,000 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Poplar Bluff, MO

4101 Highway 67 N, Poplar Bluff, MO

£63

3 Nov - 4 Nov

includes taxes & fees

7.8/10 Good! (1,002 reviews)

[](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### The Farmstead Hotel

778 E 3rd St, Caruthersville, MO

£74

2 Nov - 3 Nov

includes taxes & fees

8.6/10 Excellent! (436 reviews)

[](https://expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Fairfield Inn & Suites by Marriott Poplar Bluff](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove, Poplar Bluff, MO

£91

9 Nov - 10 Nov

includes taxes & fees

9.4/10 Exceptional! (830 reviews)

[](https://expedia.co.uk/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

![Comfort Inn Festus - St Louis South](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Comfort Inn Festus - St Louis South

1303 Veterans Blvd, Festus, MO

£71

9 Nov - 10 Nov

includes taxes & fees

7.8/10 Good! (896 reviews)

[](https://expedia.co.uk/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information)

## Hotels in Southeast Missouri with star rating

![4 Star Hotels](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_w.jpg)

4 Star Hotels

1 properties

[](https://expedia.co.uk/4Star-Southeast-Missouri-Hotels.s40-0-d6058763.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_w.jpg)

3 Star Hotels

53 properties

[](https://expedia.co.uk/3Star-Southeast-Missouri-Hotels.s30-0-d6058763.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_w.jpg)

2 Star Hotels

124 properties

[](https://expedia.co.uk/2Star-Southeast-Missouri-Hotels.s20-0-d6058763.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Southeast Missouri hotel for you.

### How can I save on a Southeast Missouri hotel booking with Expedia?

> Members always get our best prices. Find our best Southeast Missouri hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Southeast Missouri hotel?

> Prices for hotels in Southeast Missouri often vary, but you can find a great deal from £47 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

## Explore a world of travel with Expedia

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-   [Allenville Hotels](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels)
-   [Annapolis Hotels](https://www.expedia.co.uk/Annapolis-Hotels.d6282465.Travel-Guide-Hotels)
-   [Arcadia Hotels](https://www.expedia.co.uk/Arcadia-Hotels.d6346857.Travel-Guide-Hotels)
-   [Belleview Hotels](https://www.expedia.co.uk/Belleview-Hotels.d3000444413.Travel-Guide-Hotels)
-   [Bismarck Hotels](https://www.expedia.co.uk/Bismarck-Hotels.d553248634983538264.Travel-Guide-Hotels)
-   [B&B in Black](https://www.expedia.co.uk/Black-Bed-And-Breakfasts.d3000444470-aaBedAndBreakfasts.Travel-Guide-Accommodation)
-   [Black Hotels](https://www.expedia.co.uk/Black-Hotels.d3000444470.Travel-Guide-Hotels)
-   [Caledonia Hotels](https://www.expedia.co.uk/Caledonia-Hotels.d6359344.Travel-Guide-Hotels)
-   [Centerville Hotels](https://www.expedia.co.uk/Centerville-Hotels.d553248634983078632.Travel-Guide-Hotels)
-   [Desloge Hotels](https://www.expedia.co.uk/Desloge-Hotels.d55671.Travel-Guide-Hotels)
-   [Doe Run Hotels](https://www.expedia.co.uk/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels)
-   [Ellington Hotels](https://www.expedia.co.uk/Ellington-Hotels.d3000444859.Travel-Guide-Hotels)
-   [Farmington Hotels](https://www.expedia.co.uk/Farmington-Hotels.d6058764.Travel-Guide-Hotels)
-   [Flat River Hotels](https://www.expedia.co.uk/Flat-River-Hotels.d183474.Travel-Guide-Hotels)
-   [Fredericktown Hotels](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels)
-   [Friedheim Hotels](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels)
-   [Glen Allen Hotels](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels)
-   [Ironton Hotels](https://www.expedia.co.uk/Ironton-Hotels.d6053585.Travel-Guide-Hotels)
-   [Hotels near Johnson's Shut-ins State Park](https://www.expedia.co.uk/Johnsons-Shut-Ins-State-Park-Hotels.0-l553248621555612544-0.Travel-Guide-Filter-Hotels)
-   [Junction City Hotels](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels)
-   [Leadwood Hotels](https://www.expedia.co.uk/Leadwood-Hotels.d3000349432.Travel-Guide-Hotels)
-   [Gay-Friendly Hotels in Lesterville](https://www.expedia.co.uk/Lesterville-Hotels-Gay-Friendly-Hotel.0-0-d3000445174-tGayFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Lesterville Hotels](https://www.expedia.co.uk/Lesterville-Hotels.d3000445174.Travel-Guide-Hotels)
-   [Marble Hill Hotels](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels)
-   [Marquand Hotels](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels)
-   [Middle Brook Hotels](https://www.expedia.co.uk/Middle-Brook-Hotels.d3000445241.Travel-Guide-Hotels)
-   [Park Hills Hotels](https://www.expedia.co.uk/Park-Hills-Hotels.d183485.Travel-Guide-Hotels)
-   [Piedmont Hotels](https://www.expedia.co.uk/Piedmont-Hotels.d3000445413.Travel-Guide-Hotels)
-   [Pilot Knob Hotels](https://www.expedia.co.uk/Pilot-Knob-Hotels.d3000008143.Travel-Guide-Hotels)
-   [Gay-Friendly Hotels in Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff-Hotels-Gay-Friendly-Hotel.0-0-d9449-tGayFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Sedgewickville Hotels](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels)
-   [Wappapello Hotels](https://www.expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels)
-   [Williamsville Hotels](https://www.expedia.co.uk/Williamsville-Hotels.d553248634983506457.Travel-Guide-Hotels)

-   [Flights to Bonne Terre](https://www.expedia.co.uk/Cheap-Flights-To-Bonne-Terre.d55598.Travel-Guide-Flights)
-   [Flights to Desloge](https://www.expedia.co.uk/Cheap-Flights-To-Desloge.d55671.Travel-Guide-Flights)
-   [Flights to Dexter](https://www.expedia.co.uk/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights)
-   [Flights to Park Hills](https://www.expedia.co.uk/Cheap-Flights-To-Park-Hills.d183485.Travel-Guide-Flights)
-   [Flights to Wappapello](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights)
-   [Flights from Cape Girardeau Municipal](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport)
-   [Flights from Potosi](https://www.expedia.co.uk/lp/flights/181478/flights-from-potosi)
-   [Flights from Park Hills](https://www.expedia.co.uk/lp/flights/183485/flights-from-park-hills)
-   [Flights from Ste Genevieve](https://www.expedia.co.uk/lp/flights/183502/flights-from-ste-genevieve)
-   [Flights from Pilot Knob](https://www.expedia.co.uk/lp/flights/3000008143/flights-from-pilot-knob)
-   [Flights from Doe Run](https://www.expedia.co.uk/lp/flights/3000349343/flights-from-doe-run)
-   [Flights from Tiff](https://www.expedia.co.uk/lp/flights/3000349564/flights-from-tiff)
-   [Flights from Black](https://www.expedia.co.uk/lp/flights/3000444470/flights-from-black)
-   [Flights from Lesterville](https://www.expedia.co.uk/lp/flights/3000445174/flights-from-lesterville)
-   [Flights from Dexter](https://www.expedia.co.uk/lp/flights/55097/flights-from-dexter)
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-   [Flights from Marquand](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand)
-   [Flights from Zalma](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma)
-   [Flights from Ellsinore](https://www.expedia.co.uk/lp/flights/553248634983439149/flights-from-ellsinore)
-   [Flights from Viburnum](https://www.expedia.co.uk/lp/flights/553248634983489800/flights-from-viburnum)
-   [Flights from Bonne Terre](https://www.expedia.co.uk/lp/flights/55598/flights-from-bonne-terre)
-   [Flights from Jackson](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson)
-   [Flights from Farmington](https://www.expedia.co.uk/lp/flights/6058764/flights-from-farmington)
-   [Flights from Annapolis](https://www.expedia.co.uk/lp/flights/6282465/flights-from-annapolis)
-   [Flights from Arcadia](https://www.expedia.co.uk/lp/flights/6346857/flights-from-arcadia)
-   [Flights from Poplar Bluff](https://www.expedia.co.uk/lp/flights/9449/flights-from-poplar-bluff)
-   [Flights from Atlanta (ATL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau)
-   [Flights from Birmingham (BHM) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau)
-   [Flights from Sedalia (DMO) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau)
-   [Flights from Dublin (DUB) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau)
-   [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau)
-   [Flights from Los Angeles (LAX) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/lax/pof/los-angeles-to-poplar-bluff)
-   [Flights from London (LHR) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau)
-   [Flights from Lewiston (LWS) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau)
-   [Flights from Carbondale (MDH) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/mdh/pof/carbondale-to-poplar-bluff)
-   [Flights from Chicago (MDW) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau)
-   [Flights from Stow (MMN) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau)
-   [Flights from Pittsburgh (PIT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/pit/pof/pittsburgh-to-poplar-bluff)
-   [Flights from Pasco (PSC) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau)
-   [Flights from San Antonio (SAT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/sat/pof/san-antonio-to-poplar-bluff)
-   [Flights from St. Louis (STL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau)
-   [Flights from Tijuana (TIJ) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau)

-   [Visit Bonne Terre](https://www.expedia.co.uk/Bonne-Terre.dx55598)
-   [Cadet Holidays](https://www.expedia.co.uk/Cadet.d3000349308.Holidays-City-Breaks)
-   [Caledonia Holidays](https://www.expedia.co.uk/Caledonia.d6359344.Holidays-City-Breaks)
-   [Dexter Holidays](https://www.expedia.co.uk/Dexter.d55097.Holidays-City-Breaks)
-   [Visit Farmington](https://www.expedia.co.uk/Farmington.dx6058764)
-   [Fourche Valley Golf Club](https://www.expedia.co.uk/Fourche-Valley-Golf-Club-Potosi.d553248621561876443.Attraction)
-   [Visit Fredericktown](https://www.expedia.co.uk/Fredericktown.dx55114)
-   [Leadwood Holidays](https://www.expedia.co.uk/Leadwood.d3000349432.Holidays-City-Breaks)
-   [Visit Lesterville](https://www.expedia.co.uk/Lesterville.dx3000445174)
-   [Visit Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff.dx9449)
-   [Visit Potosi](https://www.expedia.co.uk/Potosi.dx181478)
-   [Powder Mill Cave Natural Area](https://www.expedia.co.uk/Powder-Mill-Cave-Natural-Area-Ellington.d553248622784732009.Attraction)
-   [Ste Genevieve Holidays](https://www.expedia.co.uk/Ste-Genevieve.d183502.Holidays-City-Breaks)
-   [Van Buren Holidays](https://www.expedia.co.uk/Van-Buren.d183504.Holidays-City-Breaks)

-   [Car hire Black](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Black.d3000444470.Car-Hire-Guide)
-   [Rental cars Cape Girardeau Municipal airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide)
-   [Car hire Ste Genevieve](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Ste-Genevieve.d183502.Car-Hire-Guide)
-   [Car hire Tiff](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Tiff.d3000349564.Car-Hire-Guide)
-   [Hertz Rental Cars in Centerville](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Centerville.d553248634983078632-c40.Car-Rental-Guide-Suppliers)
-   [Island Car Rentals Rental Cars in Cobalt](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers)
-   [Redspot Rental Cars in Oran](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers)
-   [Thrifty Car Rental Rental Cars in Belgrade](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-Belgrade.d553248635975850450-c45.Car-Rental-Guide-Suppliers)

-   [Doe Run Holiday Rentals](https://www.expedia.co.uk/Doe-Run-Holiday-Rentals.d3000349343.Travel-Guide-HolidayRentals)
-   [Lesterville Holiday Rentals](https://www.expedia.co.uk/Lesterville-Holiday-Rentals.d3000445174.Travel-Guide-HolidayRentals)
-   [Pilot Knob Holiday Rentals](https://www.expedia.co.uk/Pilot-Knob-Holiday-Rentals.d3000008143.Travel-Guide-HolidayRentals)

-   [Book Hotels in Southeast Missouri on Expedia.com](https://www.expedia.com/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)

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