Find hotels in Southeast Missouri, MO from £41
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Our top choices for Southeast Missouri hotels
1. Fort Davidson Hotel
Fort Davidson HotelIronton
9.2 out of 10, Wonderful, (185 reviews)
"We really enjoyed our stay. It was located near everything we wanted to do in that area. It is not a new location, but it was a good value. We would stay there again."
John
The price is £101
includes taxes & fees
6 Aug - 7 Aug
2. Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (325 reviews)
"This was the perfect little place for my husband and I to stay for our little vacation. Very quiet, close to many state parks and beautiful scenery. The staff was friendly, the room was clean and organized, and the breakfast was very good. We will definitely stay there again next time we are in the area."
Katie
The price is £100
includes taxes & fees
19 Aug - 20 Aug
3. Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (305 reviews)
"The owner of this place was extremely nice. So was the cleaning staff. I would definitely stay here again."
Christine
The price is £71
includes taxes & fees
12 Aug - 13 Aug
4. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (88 reviews)
"I really enjoyed my time at the stay !"
Ronrecus
The price is £106
includes taxes & fees
30 Aug - 31 Aug
5. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,001 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
Jamie
The price is £71
includes taxes & fees
9 Aug - 10 Aug
6. Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very good, (1,002 reviews)
"Great place"
Kellie
The price is £47
includes taxes & fees
11 Aug - 12 Aug
7. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.4 out of 10, Exceptional, (105 reviews)
"Nice place to stay"
JANEEN
The price is £71
includes taxes & fees
19 Aug - 20 Aug
8. Perryville RV Resort
Perryville RV ResortPerryville
10.0 out of 10, Exceptional, (2 reviews)
"We had a amazing time it was our 4 yr anniversary"
Von
The price is £56
includes taxes & fees
4 Aug - 5 Aug
9. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (156 reviews)
"The area and room looks great and clean. The service was excellent"
Luis
The price is £79
includes taxes & fees
24 Aug - 25 Aug
10. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (637 reviews)
"Such a great place in fact it was so nice I stayed a few more nights, the casino is amazing"
James
The price is £86
includes taxes & fees
4 Aug - 5 Aug
11. Black River Motel and Restaurant
Black River Motel and RestaurantLesterville
8.6 out of 10, Excellent, (43 reviews)
"Staff was very helpful and friendly"
Douglas
The price is £91
includes taxes & fees
6 Aug - 7 Aug
12. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (658 reviews)
"This is clean well maintained hotel with excellent staff! The breakfast is better than most. Plenty of amenities are nearby!"
Michael
The price is £85
includes taxes & fees
16 Aug - 17 Aug
13. Deerfield Inn & Suites Steele Near Blytheville I 55
Deerfield Inn & Suites Steele Near Blytheville I 55Steele
7.0 out of 10, Good, (4 reviews)
"Love it, very peaceful! What else want from me"
Mary
The price is £41
includes taxes & fees
1 Aug - 2 Aug
14. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (213 reviews)
"The staff at breakfast was wonderful!"
Heather
The price is £78
includes taxes & fees
13 Aug - 14 Aug
15. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
"Nice, clean rooms"
Christi
The price is £79
includes taxes & fees
13 Aug - 14 Aug
16. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (910 reviews)
"Great overnight restful stay"
Philip
The price is £78
includes taxes & fees
23 Aug - 24 Aug
17. Sam A Baker State Park
Sam A Baker State ParkPatterson
9.0 out of 10, Wonderful, (6 reviews)
"Pet friendly, great staff. "
Charlie
The price is £106
includes taxes & fees
26 Aug - 27 Aug
18. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay 3 free drinks during happy and good supper and breakfast. Will stay in a Drury Inn whenever one is available."
Jimmie
The price is £84
includes taxes & fees
23 Aug - 24 Aug
19. Holiday Inn Express & Suites Farmington by IHG
Holiday Inn Express & Suites Farmington by IHGFarmington
8.6 out of 10, Excellent, (427 reviews)
"Great location friendly staff "
Tara
The price is £80
includes taxes & fees
30 Aug - 31 Aug
20. Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (191 reviews)
"It was lovely"
Amber
The price is £79
includes taxes & fees
26 Aug - 27 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (88 reviews)
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Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Crane Lake Recreation Area to K Bridge Recreation Area.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is £47 per night from 11 Aug to 12 Aug
£47
11 Aug - 12 Aug
includes taxes & fees
Hotels in Southeast Missouri with star rating
4 Star Hotels
2 properties
Explore a world of travel with Expedia
- Rustic River Cabin Getaway
- B&B in Black
- Bloomsdale Suite at Baetje Farms
- Adults Only Resorts & in Cape Girardeau
- “Brickyard”
- The Riverview
- Tru By Hilton Cape Girardeau
- Doe Run Hotels
- Current River Cottage
- Doniphan Hotels
- Ellington Hotels
- Hogan’s Hideout Bonnie Manor
- Crown Pointe Lodge
- High Hope Tree House #1 @Spring Lake Ranch
- ❤️ THE MAGIC TIPI RETREAT
- Farmington Hotels
- Fredericktown Hotels
- Postcard Cabins St Francois
- Glen Allen Hotels
- Hotels near Johnson's Shut-ins State Park
- Junction City Hotels
- Black River Motel and Restaurant
- Gay-Friendly Hotels in Lesterville
- Wilderness Lodge
- Lithium Hotels
- Middle Brook Hotels
- New Offenburg Hotels
- Urban Lofts
- Dancing Under Red Skies Tree House @Spring Lake
- Potosi Hotels
- Dexter Inn
- Drury Plaza Hotel Cape Girardeau Conference Center
- Fairfield Inn & Suites by Marriott Sikeston
- Hampton Inn Sikeston
- The cabin in Eden
- Towneplace Suites by Marriott Sikeston
- Travel Inn & Suites
- Sikeston Hotels
- Hotels with Connecting Rooms in Southeast Missouri
- Pet-Friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Hotels near Southeast Missouri State University
- Peaceful 4BR ranch w/ hot tub
- Silo Farm Haus
- 1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi
- Winona Hotels
- Flights to Bonne Terre
- Flights to Cape Girardeau
- Flights to Desloge
- Flights to Park Hills
- Flights to Wappapello
- Flights from Cape Girardeau Municipal
- Flights from Ste Genevieve
- Flights from Black
- Flights from Lesterville
- Flights from Dexter
- Flights from Viburnum
- Flights from Bonne Terre
- Flights from Arcadia
- Flights from London (LHR) to Cape Girardeau (CGI)
