Title: Hotels in Southeast Missouri - Best Southeast Missouri Hotels from £45 - Fully Refundable Options - Expedia.co.uk

  

[Southeast Missouri Travel Guide](https://expedia.co.uk/Southeast-Missouri.dx6058763)[Holiday Rentals in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Holiday-Rentals.d6058763.Travel-Guide-HolidayRentals)[Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks)

![The Current River flows through the Ozark National Scenic Riverway through the mountains of Missouri](https://images.trvl-media.com/place/553248635976196024/558eb86b-b1ac-4ef2-8a0c-6bebbb1e2aae.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find hotels in Southeast Missouri, MO from £45

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## Go beyond your typical stay in Southeast Missouri

Cabin

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&lodging=CABIN)

Hot tub

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&amenities=HOT_TUB)

Pool

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&amenities=POOL)

Family friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&travelerType=family_friendly)

Pet friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&amenities=PETS)

Waterpark

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&amenities=WATER_PARK)

Apart­ment

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&lodging=APARTMENT)

Farm

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&lodging=AGRITOURISM)

Cottage

[](https://www.expedia.co.uk/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&lodging=COTTAGE)

## Check prices for these dates

Tonight

[17 Sept - 18 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-09-17&endDate=2025-09-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[18 Sept - 19 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-09-18&endDate=2025-09-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-09-19&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top 10 Southeast Missouri hotels and places to stay

## Our top choices for Southeast Missouri hotels

![Exterior](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/3b6f469d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Cabin, 2 Queen Beds | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/aa026ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/3ec0c384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Cabin, 1 Queen Bed | 1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/de973d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Postcard Cabins St. Francois

French Village

10/10

Exceptional

(30)

"Peaceful, beautiful stay. "

£98

includes taxes & fees

18 Sept - 19 Sept

[](https://www.expedia.co.uk/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d234bb55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/3a2c35d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Refrigerator | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d7244881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Farmington

Farmington

8.0/10

Very good

(588)

"Location "

£48

includes taxes & fees

18 Sept - 19 Sept

[](https://www.expedia.co.uk/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/8003191a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/060976ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/13275a81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Farmstead Hotel

Caruthersville

8.8/10

Excellent

(410)

"Great place. "

£96

includes taxes & fees

16 Oct - 17 Oct

[](https://www.expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Perryville by IHG

Perryville

9.4/10

Exceptional

(504)

"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "

£71

includes taxes & fees

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1010)

"Was a clean room, nice staff, good parking "

£70

includes taxes & fees

22 Sept - 23 Sept

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

Cape Girardeau

9.0/10

Wonderful

(1004)

"My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there."

£58

includes taxes & fees

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

Cape Girardeau

9.4/10

Exceptional

(995)

"Excellent place. Really friendly staff"

£74

includes taxes & fees

2 Oct - 3 Oct

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Building design](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/f4d876e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/7e9b49ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/c41116cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

8.0/10

Very good

(1010)

"Great location"

£45

includes taxes & fees

5 Oct - 6 Oct

[](https://www.expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(618)

"Excellent place to stay. Breakfast was good and staff was friendly. "

£67

includes taxes & fees

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Perryville

Perryville

8.4/10

Very good

(909)

" Love the stay and staff was great "

£61

includes taxes & fees

24 Sept - 25 Sept

[](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/f46408d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/a5281c8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/49c875c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Hayti Caruthersville

Hayti

9.4/10

Exceptional

(1002)

"Nice place for a over night stay would recamend."

£78

includes taxes & fees

28 Sept - 29 Sept

[](https://www.expedia.co.uk/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information)

![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/720261dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/77434452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/6d872386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/2d71c942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

9.4/10

Exceptional

(683)

"Great place to stay!"

£124

includes taxes & fees

5 Oct - 6 Oct

[](https://www.expedia.co.uk/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/705e1bff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/fc42ec39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Non Smoking | 6 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/4d9ecdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn Festus - St Louis South

Festus

8.0/10

Very good

(876)

"The stay and food "

£66

includes taxes & fees

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1011)

"Very nice hotel and nice staff "

£74

includes taxes & fees

2 Oct - 3 Oct

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1003)

"Nice place. Good price "

£58

includes taxes & fees

18 Sept - 19 Sept

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub) | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

Sikeston

9.4/10

Exceptional

(1004)

"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"

£76

includes taxes & fees

28 Sept - 29 Sept

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s play area – outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/0c1d1e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/db5aadc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Echo Bluff State Park

Eminence

9.4/10

Exceptional

(208)

"Beautiful location…excellent service and facilities / grounds were clean and well kept."

£129

includes taxes & fees

16 Oct - 17 Oct

[](https://www.expedia.co.uk/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information)

![Standard Room, 1 King Bed | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/2cf60fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/04ce172c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/b3da6b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/05c7ee11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Potosi

Potosi

7.0/10

Good

(367)

"The room was very good for the price."

£42

includes taxes & fees

18 Sept - 19 Sept

[](https://www.expedia.co.uk/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/e9e97147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/e66aa4eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/a1c40704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

8.0/10

Very good

(852)

"I enjoyed my stay. The rooms were clean and the staff was friendly. "

£78

includes taxes & fees

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-01&endDate=2025-10-02&regionId=6058763&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:26 Sept - 28 Sept

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/14339969.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Tiny Houses of French Village

French Village

10/10Exceptional (3 reviews)

9% off

£418

for 2 nights, 1 home

£209 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=83516509&adults=2)

![BBQ/picnic Area](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/708e4b63.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Current River Inn

Van Buren

8.2/10Very good (154 reviews)

15% off

£138

for 2 nights, 1 room

£69 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=47039515&adults=2)

![Deluxe Double Room | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

VIP Access

### EC Reed's Mercantile and Hotel

Marble Hill

9.6/10Exceptional (77 reviews)

25% off

£154

for 2 nights, 1 room

£77 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=74660768&adults=2)

![Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Rockwood Inn

Cape Girardeau

10/10Exceptional (16 reviews)

15% off

£280

for 2 nights, 1 room

£140 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=105486893&adults=2)

![Standard Double Room, 2 Queen Beds, Transfer Shower | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/690c1aa2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Century Casino & Hotel Caruthersville

Caruthersville

8.2/10Very good (66 reviews)

13% off

£227

for 2 nights, 1 room

£113 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=111402094&adults=2)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/13000000/12590000/12582100/12582009/57db158c.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Shepherd Mountain Inn

Ironton

9.2/10Wonderful (296 reviews)

10% off

£197

for 2 nights, 1 room

£99 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=12582009&adults=2)

![Children’s play area – outdoor](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/e8909449.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Honeysuckle Inn - Mountain View

Mountain View

8.6/10Excellent (310 reviews)

15% off

£201

for 2 nights, 1 room

£100 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=42093410&adults=2)

![Shared kitchen](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/66a0aee5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Arcadia Academy

Arcadia

9.8/10Exceptional (8 reviews)

14% off

£186

for 2 nights, 1 room

£93 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=112360980&adults=2)

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Farmstead Hotel

Caruthersville

8.8/10Excellent (410 reviews)

13% off

£171

for 2 nights, 1 room

£85 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=89303450&adults=2)

![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

8.0/10Very good (1,010 reviews)

15% off

£121

for 2 nights, 1 room

£60 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=16153&adults=2)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10Excellent (618 reviews)

20% off

£164

for 2 nights, 1 room

£82 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=53348099&adults=2)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Comfort Inn Festus - St Louis South

Festus

8.0/10Very good (876 reviews)

15% off

£159

for 2 nights, 1 room

£79 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=40138&adults=2)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)

### Accommodation near Southeast Missouri attractions

[](https://expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels)

#### Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

[See properties](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621554122994)

[](https://expedia.co.uk/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels)

#### Century Casino Caruthersville

Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532655201)

## Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

[See all hotels in Southeast Missouri](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-01&endDate=2025-10-02&adults=2&regionId=6058763)

![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=899&h=541&p=1&q=high)

## Top Southeast Missouri Hotel Reviews

![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Very busy from September 12 to September 14 with one working elevator. Great food. Comfortable room. The bathroom could have used an exhaust fan. Steam and heat from the shower didn't affect the room temperature very much. Sofa bed matress was thin. My son didn’t complain about it though. Shower got hot quick, but you cannot adjust the shower pressure."

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Motel 6 Poplar Bluff, MO](//images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg)

### Motel 6 Poplar Bluff, MO

10/10 Excellent

"Fantastic staff, cleaning crew and it was a wonderful experience."

[](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![The Farmstead Hotel](//images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg)

### The Farmstead Hotel

10/10 Excellent

"Newly renovated, very spacious and clean hotel."

[](https://expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg)

### Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent

"Very helpful staff and comfirtable room"

[](https://expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"First time staying here. I will definitely be back!"

[](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Always a good place. The Drury’s brands are always my choice. "

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

10/10 Excellent

"The service was top notch! There was several separate large groups staying at the hotel, and the staff went the extra mile and moved up breakfast since most people were leaving at 7am. Room and Beds were comfy and clean. Plenty of hot water. Kids enjoyed the amenities of dinner, breakfast (great), and pool. The Bavarian theme actually was super cute. A lot of hotels are going for modern and sleek ( which to me translates to sterile ( which I totally get translates to clean) but that motif comes off cold. It’s refreshing to see a good mix of the past and present. "

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"Spacious room "

[](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg)

### La Quinta Inn & Suites by Wyndham Festus - St. Louis South

10/10 Excellent

"nice staff, good room"

[](https://expedia.co.uk/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information)

## More cheap stays in Southeast Missouri

![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### The Riverview

777 Main St, Cape Girardeau, MO

£94

21 Sept - 22 Sept

includes taxes & fees

9.2/10 Wonderful! (416 reviews)

[](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St, Farmington, MO

£45

5 Oct - 6 Oct

includes taxes & fees

8/10 Very Good! (1,009 reviews)

[](https://expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### The Farmstead Hotel

778 E 3rd St, Caruthersville, MO

£96

16 Oct - 17 Oct

includes taxes & fees

8.6/10 Excellent! (410 reviews)

[](https://expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Poplar Bluff, MO

4101 Highway 67 N, Poplar Bluff, MO

£61

18 Sept - 19 Sept

includes taxes & fees

7.8/10 Good! (1,007 reviews)

[](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau, MO

£58

18 Sept - 19 Sept

includes taxes & fees

8.8/10 Excellent! (1,001 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy, Cape Girardeau, MO

£58

21 Sept - 22 Sept

includes taxes & fees

9/10 Wonderful! (1,004 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

## Hotels in Southeast Missouri with star rating

![4 Star Hotels](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae_w.jpg)

4 Star Hotels

1 properties

[](https://expedia.co.uk/4Star-Southeast-Missouri-Hotels.s40-0-d6058763.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_w.jpg)

3 Star Hotels

52 properties

[](https://expedia.co.uk/3Star-Southeast-Missouri-Hotels.s30-0-d6058763.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_w.jpg)

2 Star Hotels

130 properties

[](https://expedia.co.uk/2Star-Southeast-Missouri-Hotels.s20-0-d6058763.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Southeast Missouri hotel for you.

### How can I save on a Southeast Missouri hotel booking with Expedia?

> Members always get our best prices. Find our best Southeast Missouri hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Southeast Missouri hotel?

> Prices for hotels in Southeast Missouri often vary, but you can find a great deal from £45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

## Explore a world of travel with Expedia

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-   [Desloge Hotels](https://www.expedia.co.uk/Desloge-Hotels.d55671.Travel-Guide-Hotels)
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-   [Ellington Hotels](https://www.expedia.co.uk/Ellington-Hotels.d3000444859.Travel-Guide-Hotels)
-   [Farmington Hotels](https://www.expedia.co.uk/Farmington-Hotels.d6058764.Travel-Guide-Hotels)
-   [Flat River Hotels](https://www.expedia.co.uk/Flat-River-Hotels.d183474.Travel-Guide-Hotels)
-   [Fredericktown Hotels](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels)
-   [Friedheim Hotels](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels)
-   [Glen Allen Hotels](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels)
-   [Ironton Hotels](https://www.expedia.co.uk/Ironton-Hotels.d6053585.Travel-Guide-Hotels)
-   [Hotels near Johnson's Shut-ins State Park](https://www.expedia.co.uk/Johnsons-Shut-Ins-State-Park-Hotels.0-l553248621555612544-0.Travel-Guide-Filter-Hotels)
-   [Junction City Hotels](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels)
-   [Leadwood Hotels](https://www.expedia.co.uk/Leadwood-Hotels.d3000349432.Travel-Guide-Hotels)
-   [Gay-Friendly Hotels in Lesterville](https://www.expedia.co.uk/Lesterville-Hotels-Gay-Friendly-Hotel.0-0-d3000445174-tGayFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Lesterville Hotels](https://www.expedia.co.uk/Lesterville-Hotels.d3000445174.Travel-Guide-Hotels)
-   [Marble Hill Hotels](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels)
-   [Marquand Hotels](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels)
-   [Middle Brook Hotels](https://www.expedia.co.uk/Middle-Brook-Hotels.d3000445241.Travel-Guide-Hotels)
-   [Park Hills Hotels](https://www.expedia.co.uk/Park-Hills-Hotels.d183485.Travel-Guide-Hotels)
-   [Piedmont Hotels](https://www.expedia.co.uk/Piedmont-Hotels.d3000445413.Travel-Guide-Hotels)
-   [Pilot Knob Hotels](https://www.expedia.co.uk/Pilot-Knob-Hotels.d3000008143.Travel-Guide-Hotels)
-   [Gay-Friendly Hotels in Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff-Hotels-Gay-Friendly-Hotel.0-0-d9449-tGayFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Sedgewickville Hotels](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels)
-   [Wappapello Hotels](https://www.expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels)
-   [Williamsville Hotels](https://www.expedia.co.uk/Williamsville-Hotels.d553248634983506457.Travel-Guide-Hotels)

-   [Flights to Bonne Terre](https://www.expedia.co.uk/Cheap-Flights-To-Bonne-Terre.d55598.Travel-Guide-Flights)
-   [Flights to Desloge](https://www.expedia.co.uk/Cheap-Flights-To-Desloge.d55671.Travel-Guide-Flights)
-   [Flights to Dexter](https://www.expedia.co.uk/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights)
-   [Flights to Park Hills](https://www.expedia.co.uk/Cheap-Flights-To-Park-Hills.d183485.Travel-Guide-Flights)
-   [Flights to Wappapello](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights)
-   [Flights from Cape Girardeau Municipal](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport)
-   [Flights from Potosi](https://www.expedia.co.uk/lp/flights/181478/flights-from-potosi)
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-   [Flights from Doe Run](https://www.expedia.co.uk/lp/flights/3000349343/flights-from-doe-run)
-   [Flights from Tiff](https://www.expedia.co.uk/lp/flights/3000349564/flights-from-tiff)
-   [Flights from Black](https://www.expedia.co.uk/lp/flights/3000444470/flights-from-black)
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-   [Flights from Ellsinore](https://www.expedia.co.uk/lp/flights/553248634983439149/flights-from-ellsinore)
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-   [Flights from Bonne Terre](https://www.expedia.co.uk/lp/flights/55598/flights-from-bonne-terre)
-   [Flights from Jackson](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson)
-   [Flights from Farmington](https://www.expedia.co.uk/lp/flights/6058764/flights-from-farmington)
-   [Flights from Annapolis](https://www.expedia.co.uk/lp/flights/6282465/flights-from-annapolis)
-   [Flights from Arcadia](https://www.expedia.co.uk/lp/flights/6346857/flights-from-arcadia)
-   [Flights from Poplar Bluff](https://www.expedia.co.uk/lp/flights/9449/flights-from-poplar-bluff)
-   [Flights from Atlanta (ATL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau)
-   [Flights from Birmingham (BHM) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau)
-   [Flights from Sedalia (DMO) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau)
-   [Flights from Dublin (DUB) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau)
-   [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau)
-   [Flights from Los Angeles (LAX) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/lax/pof/los-angeles-to-poplar-bluff)
-   [Flights from London (LHR) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau)
-   [Flights from Lewiston (LWS) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau)
-   [Flights from Carbondale (MDH) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/mdh/pof/carbondale-to-poplar-bluff)
-   [Flights from Chicago (MDW) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau)
-   [Flights from Stow (MMN) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau)
-   [Flights from Pittsburgh (PIT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/pit/pof/pittsburgh-to-poplar-bluff)
-   [Flights from Pasco (PSC) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau)
-   [Flights from San Antonio (SAT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/sat/pof/san-antonio-to-poplar-bluff)
-   [Flights from St. Louis (STL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau)
-   [Flights from Tijuana (TIJ) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau)

-   [Visit Bonne Terre](https://www.expedia.co.uk/Bonne-Terre.dx55598)
-   [Cadet Holidays](https://www.expedia.co.uk/Cadet.d3000349308.Holidays-City-Breaks)
-   [Caledonia Holidays](https://www.expedia.co.uk/Caledonia.d6359344.Holidays-City-Breaks)
-   [Dexter Holidays](https://www.expedia.co.uk/Dexter.d55097.Holidays-City-Breaks)
-   [Visit Farmington](https://www.expedia.co.uk/Farmington.dx6058764)
-   [Fourche Valley Golf Club](https://www.expedia.co.uk/Fourche-Valley-Golf-Club-Potosi.d553248621561876443.Attraction)
-   [Visit Fredericktown](https://www.expedia.co.uk/Fredericktown.dx55114)
-   [Leadwood Holidays](https://www.expedia.co.uk/Leadwood.d3000349432.Holidays-City-Breaks)
-   [Visit Lesterville](https://www.expedia.co.uk/Lesterville.dx3000445174)
-   [Visit Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff.dx9449)
-   [Visit Potosi](https://www.expedia.co.uk/Potosi.dx181478)
-   [Powder Mill Cave Natural Area](https://www.expedia.co.uk/Powder-Mill-Cave-Natural-Area-Ellington.d553248622784732009.Attraction)
-   [Ste Genevieve Holidays](https://www.expedia.co.uk/Ste-Genevieve.d183502.Holidays-City-Breaks)
-   [Van Buren Holidays](https://www.expedia.co.uk/Van-Buren.d183504.Holidays-City-Breaks)

-   [Car hire Black](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Black.d3000444470.Car-Hire-Guide)
-   [Rental cars Cape Girardeau Municipal airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide)
-   [Car hire Ste Genevieve](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Ste-Genevieve.d183502.Car-Hire-Guide)
-   [Car hire Tiff](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Tiff.d3000349564.Car-Hire-Guide)
-   [Hertz Rental Cars in Centerville](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Centerville.d553248634983078632-c40.Car-Rental-Guide-Suppliers)
-   [Island Car Rentals Rental Cars in Cobalt](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers)
-   [Redspot Rental Cars in Oran](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers)
-   [Thrifty Car Rental Rental Cars in Belgrade](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-Belgrade.d553248635975850450-c45.Car-Rental-Guide-Suppliers)

-   [Doe Run Holiday Rentals](https://www.expedia.co.uk/Doe-Run-Holiday-Rentals.d3000349343.Travel-Guide-HolidayRentals)
-   [Lesterville Holiday Rentals](https://www.expedia.co.uk/Lesterville-Holiday-Rentals.d3000445174.Travel-Guide-HolidayRentals)
-   [Pilot Knob Holiday Rentals](https://www.expedia.co.uk/Pilot-Knob-Holiday-Rentals.d3000008143.Travel-Guide-HolidayRentals)

-   [Book Hotels in Southeast Missouri on Expedia.com](https://www.expedia.com/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)

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