Title: Southeast Missouri Travel Guide: Best of Southeast Missouri, Missouri Travel 2026 | Expedia.co.uk [Hotels in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Holiday Rentals in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Holiday-Rentals.d6058763.Travel-Guide-HolidayRentals)[Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks) # Southeast Missouri Travel Guide ## Tourist Guide ![150th anniversary of the historic French fort. ](https://images.trvl-media.com/place/148078/1ef720df-0786-4e45-8a4f-890d982b757b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Incredible views and incredible hike all close to our current home... what's not to love? Regardless this beauty is worth the drive. #bestof5 #Missouri #stateparks #colorful #blue Read more about this experience here: https://pagesoftravel.org/2016/05/20/johnson-shut-ins-state-park/](https://images.trvl-media.com/place/553248635976433620/2bf32d3d-8aa9-45f2-93ad-bdc1b65fa0d7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Another spectacular sight at the Johnson Shut-Ins. #GoPro #bestof5 #blue #colorful #PagesofTravel #wanderlust #water](https://images.trvl-media.com/place/227/1c8bd772-78a9-4887-8af5-50e1d0f27748.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Breathtaking view at the dam by the road and some small trails for walking as well!](https://images.trvl-media.com/place/635033036780072960/d91a319c-d0dc-4302-9360-97af4b36e4b3.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The hike is well worth this view at the top of Inspiration Point.](https://images.trvl-media.com/place/820/f194d2c0-30cb-4042-92da-43d24696c201.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Southeast Missouri Things to do ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX_SPRING_PROMO_6058763) - Top hotels in Southeast Missouri - Top Holiday Rentals in Southeast Missouri ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel Cape Girardeau Conference Center 3351 Percy Drive Cape Girardeau MO Fully refundableReserve now, pay when you stay £85 19 Mar - 20 Mar includes taxes & fees Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ... 9.6/10 Exceptional! (1,003 reviews) Very nice Reviewed on 14 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F03%2F2026&endDate=20%2F03%2F2026&selected=17269948&PinnedHotelID=17269948&HadPinnedHotel=true®ionId=6058763) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Riverview 777 Main St Cape Girardeau MO £73 26 Mar - 27 Mar includes taxes & fees Stay at this business-friendly hotel in Cape Girardeau. Enjoy free Wi-Fi, free parking and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and ... 9.4/10 Exceptional! (526 reviews) Lovely property. I don’t gamble, but if you do, it’s clearly convenient to the casino. Comfortable bed, very clean room, lovely staff Reviewed on 8 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=26%2F03%2F2026&endDate=27%2F03%2F2026&selected=105081384&PinnedHotelID=105081384&HadPinnedHotel=true®ionId=6058763) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Cape Girardeau 3303 Campster Drive Cape Girardeau MO £77 22 Mar - 23 Mar includes taxes & fees Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean ... 9.4/10 Exceptional! (1,000 reviews) Easy parking. Very clean room. Accommodating. Nice and helpful staff. Reviewed on 11 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F03%2F2026&endDate=23%2F03%2F2026&selected=40831&PinnedHotelID=40831&HadPinnedHotel=true®ionId=6058763) [See all 621 properties in Southeast Missouri](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=16%2F03%2F2026&endDate=17%2F03%2F2026®ionId=6058763) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/d4a93b47_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy 7555 State Hwy Y French Village MO Stay at this cabin in French Village. Enjoy free parking, patios and climate control. 9.8/10 Exceptional! (56 reviews) Absolutely amazing time as always. Staff is beyond great. Always ready to help and never in the way Reviewed on 2 Mar 2026 [](https://expedia.co.uk/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information) ![St Francis River: The Blue Yurt and Hot Tub](https://images.trvl-media.com/lodging/104000000/103280000/103277100/103277006/152bb922_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### St Francis River: The Blue Yurt and Hot Tub Fredericktown MO Stay at this cabin in Fredericktown. Enjoy air conditioning. 8.8/10 Excellent! (20 reviews) Everything was easy to understand to find the place I wanted. Host is 5 stars Reviewed on 2 Jan 2026 [](https://expedia.co.uk/Fredericktown-Hotels-St-Francis-River-The-Blue-Yurt-And-Hot-Tub.h103277006.Hotel-Information) ![Johnson's Shut-ins State Park](https://images.trvl-media.com/lodging/113000000/112020000/112017900/112017805/7a5cb69e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Johnson's Shut-ins State Park 148 Taum Sauk Trail Middle Brook MO Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ... 10/10 Exceptional! (1 review) These newer cabins are clean and have everything you need. Highly recommend! Reviewed on 5 Nov 2025 [](https://expedia.co.uk/Johnsons-Shut-Ins-State-Park.h112017805.Hotel-Information) [See all properties in Southeast Missouri](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6058763&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Southeast Missouri hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058763&startDate=2026-03-15&endDate=2026-03-16)[15 Mar - 16 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058763&startDate=2026-03-15&endDate=2026-03-16) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058763&startDate=2026-03-16&endDate=2026-03-17)[16 Mar - 17 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058763&startDate=2026-03-16&endDate=2026-03-17) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058763&startDate=20%2F03%2F2026&endDate=22%2F03%2F2026)[20 Mar - 22 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058763&startDate=20%2F03%2F2026&endDate=22%2F03%2F2026) ### Popular places to visit ![An old granite quarry that has filled with water. An beautiful spring hike around the lake got me this picture ](https://images.trvl-media.com/place/6058764/eb509a9d-6c8b-419e-867d-f4e51d5a7c33.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Elephant Rocks State Park You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks. [](https://expedia.co.uk/Elephant-Rocks-State-Park-Ironton.d553248621532648464.Attraction) ![Panorama of Academic Hall, Southeast Missouri State University ](https://images.trvl-media.com/place/553248621554122994/3bc9a5e0-c92b-4ca4-b94a-564376156913.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Southeast Missouri State University Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Attraction) ![Sunrise from the duck blind. ](https://images.trvl-media.com/place/183505/9493e565-66da-46c4-8222-30a8f5da22bb.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lake Wappapello Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants. [](https://expedia.co.uk/Lake-Wappapello-Wappapello.d553248621532648460.Attraction) ![Ozark Grist Mill](https://images.trvl-media.com/place/553248621532648450/5d510200-2188-41b5-a4e9-3dcff0b33b66.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Current River State Park Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront. [](https://expedia.co.uk/Current-River-State-Park-Salem.d553248621532648450.Attraction) ![A long exposure shot of Pickle Creek in Hawn State Park, Ste. Genevieve, Missouri](https://images.trvl-media.com/place/553248621532648475/0af6dfe5-967d-4b19-bf3b-af556468c9d3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Hawn State Park You can take time to visit Hawn State Park during your travels to Ste Genevieve. Discover the area's cafes or seek out the golf courses. [](https://expedia.co.uk/Hawn-State-Park-Ste-Genevieve.d553248621532648475.Attraction) ![Chubb Hollow Trail Overlook the Current River at Big Spring Ozark National Scenic Waterway Van Buren Missouri ](https://images.trvl-media.com/place/553248621532648457/ce3d4d6d-7dbc-46ba-9c32-f264369a1dca.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Big Spring Enjoy an outing to Big Spring during your stay in Van Buren. Wander the forests and riverfront while you're in the area. [](https://expedia.co.uk/Big-Spring-Van-Buren.d553248621532648457.Attraction) ### Things to do ![Pythian Castle](https://mediaim.expedia.com/localexpert/1103662/13a649a1-69d5-408d-8ac8-b0d187677e2a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Night Ghost Tour of Pythian Castle in Springfield Missouri £15 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/night-ghost-tour-of-pythian-castle-in-springfield-missouri.a1103662.activity-details) [See all activities in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) ## Cities near Southeast Missouri ![Majestic Clouds over Lake Wappapello Redman Creek Recreational Area The sun peaks out of some storm clouds over Lake Wappapello, creating some ](https://images.trvl-media.com/place/9449/4db2a43a-820e-400d-b69a-c971f0210624.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Poplar Bluff ![Castor River Shut-Ins Fredericktown Missouri Ozarks](https://images.trvl-media.com/place/55114/91abb0ab-7f41-436b-8c30-7968c3ac1879.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Fredericktown ![Coonville Creek St. Francois State Park 8920 US Highway 67, Bonne Terre, MO ](https://images.trvl-media.com/place/55598/7bea18c1-3b89-40ea-b0de-05793014c9f8.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Bonne Terre ![Girl in yellow dress stands on dock facing foggy lake in morning](https://images.trvl-media.com/place/181478/2fdaf33a-ed0a-496d-88f9-e1d6e30ff744.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Potosi ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [Allenville Hotels ](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Annapolis Hotels ](https://www.expedia.co.uk/Annapolis-Hotels.d6282465.Travel-Guide-Hotels) - [Arcadia Hotels ](https://www.expedia.co.uk/Arcadia-Hotels.d6346857.Travel-Guide-Hotels) - [Belleview Hotels ](https://www.expedia.co.uk/Belleview-Hotels.d3000444413.Travel-Guide-Hotels) - [Bismarck Hotels ](https://www.expedia.co.uk/Bismarck-Hotels.d553248634983538264.Travel-Guide-Hotels) - [B&B in Black ](https://www.expedia.co.uk/Black-Bed-And-Breakfasts.d3000444470-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Black Hotels ](https://www.expedia.co.uk/Black-Hotels.d3000444470.Travel-Guide-Hotels) - [Bonne Terre Hotels ](https://www.expedia.co.uk/Bonne-Terre-Hotels.d55598.Travel-Guide-Hotels) - [Caledonia Hotels ](https://www.expedia.co.uk/Caledonia-Hotels.d6359344.Travel-Guide-Hotels) - [Centerville Hotels ](https://www.expedia.co.uk/Centerville-Hotels.d553248634983078632.Travel-Guide-Hotels) - [Desloge Hotels ](https://www.expedia.co.uk/Desloge-Hotels.d55671.Travel-Guide-Hotels) - [Doe Run Hotels ](https://www.expedia.co.uk/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels) - [Ellington Hotels ](https://www.expedia.co.uk/Ellington-Hotels.d3000444859.Travel-Guide-Hotels) - [Farmington Hotels ](https://www.expedia.co.uk/Farmington-Hotels.d6058764.Travel-Guide-Hotels) - [Flat River Hotels ](https://www.expedia.co.uk/Flat-River-Hotels.d183474.Travel-Guide-Hotels) - [Fredericktown Hotels ](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels) - [Friedheim Hotels ](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Glen Allen Hotels ](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Ironton Hotels ](https://www.expedia.co.uk/Ironton-Hotels.d6053585.Travel-Guide-Hotels) - [Hotels near Johnson's Shut-ins State Park ](https://www.expedia.co.uk/Johnsons-Shut-Ins-State-Park-Hotels.0-l553248621555612544-0.Travel-Guide-Filter-Hotels) - [Junction City Hotels ](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels) - [Leadwood Hotels ](https://www.expedia.co.uk/Leadwood-Hotels.d3000349432.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Lesterville ](https://www.expedia.co.uk/Lesterville-Hotels-Gay-Friendly-Hotel.0-0-d3000445174-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Lesterville Hotels ](https://www.expedia.co.uk/Lesterville-Hotels.d3000445174.Travel-Guide-Hotels) - [Marble Hill Hotels ](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Marquand Hotels ](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels) - [Middle Brook Hotels ](https://www.expedia.co.uk/Middle-Brook-Hotels.d3000445241.Travel-Guide-Hotels) - [New Offenburg Hotels ](https://www.expedia.co.uk/New-Offenburg-Hotels.d3000349478.Travel-Guide-Hotels) - [Park Hills Hotels ](https://www.expedia.co.uk/Park-Hills-Hotels.d183485.Travel-Guide-Hotels) - [Perryville Hotels ](https://www.expedia.co.uk/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - 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[Flights to Park Hills ](https://www.expedia.co.uk/Cheap-Flights-To-Park-Hills.d183485.Travel-Guide-Flights) - [Flights to Wappapello ](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights) - [Flights from Park Hills ](https://www.expedia.co.uk/lp/flights/183485/flights-from-park-hills) - [Flights from Pilot Knob ](https://www.expedia.co.uk/lp/flights/3000008143/flights-from-pilot-knob) - [Flights from Doe Run ](https://www.expedia.co.uk/lp/flights/3000349343/flights-from-doe-run) - [Flights from Black ](https://www.expedia.co.uk/lp/flights/3000444470/flights-from-black) - [Flights from Lesterville ](https://www.expedia.co.uk/lp/flights/3000445174/flights-from-lesterville) - [Flights from Fredericktown ](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand ](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Zalma ](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Ellsinore ](https://www.expedia.co.uk/lp/flights/553248634983439149/flights-from-ellsinore) - [Flights from Bonne Terre ](https://www.expedia.co.uk/lp/flights/55598/flights-from-bonne-terre) - [Flights from Farmington ](https://www.expedia.co.uk/lp/flights/6058764/flights-from-farmington) - [Flights from Annapolis ](https://www.expedia.co.uk/lp/flights/6282465/flights-from-annapolis) - [Flights from Arcadia ](https://www.expedia.co.uk/lp/flights/6346857/flights-from-arcadia) - [Flights from Poplar Bluff ](https://www.expedia.co.uk/lp/flights/9449/flights-from-poplar-bluff) - [Flights from Los Angeles (LAX) to Poplar Bluff (POF) ](https://www.expedia.co.uk/lp/flights/lax/pof/los-angeles-to-poplar-bluff) - [Flights from Carbondale (MDH) to Poplar Bluff (POF) ](https://www.expedia.co.uk/lp/flights/mdh/pof/carbondale-to-poplar-bluff) - [Flights from Pittsburgh (PIT) to Poplar Bluff (POF) ](https://www.expedia.co.uk/lp/flights/pit/pof/pittsburgh-to-poplar-bluff) - [Flights from San Antonio (SAT) to Poplar Bluff (POF) ](https://www.expedia.co.uk/lp/flights/sat/pof/san-antonio-to-poplar-bluff) - 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