Southeast Missouri Travel Guide
Tourist Guide
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is £83 per night from 3 Nov to 4 Nov
£83
3 Nov - 4 Nov
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,002 reviews)
"Wonderful facility, staff, and hospitality. Ken"
Reviewed on 29 Oct 2026
Hampton Inn Poplar Bluff
2420 Crestwood Dr Poplar Bluff MO
The price is £76 per night from 8 Nov to 9 Nov
£76
8 Nov - 9 Nov
includes taxes & fees
Stay at this hotel in Poplar Bluff. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
9.4/10 Exceptional! (1,003 reviews)
"A great stay; very clean, comfortable and a nice breakfast."
Reviewed on 29 Oct 2026
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
The price is £81 per night from 8 Nov to 9 Nov
£81
8 Nov - 9 Nov
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios and climate control.
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
Stay at this holiday home in Ste Genevieve. Enjoy laundry facilities. Popular attractions Crown Valley Winery and Hawn State Park are located nearby.
10/10 Exceptional! (158 reviews)
"This place is absolutely gorgeous! We really enjoyed our stay. The silo farm haus was serene, clean and comfortable. Thank you for a wonderful stay!"
Reviewed on 19 Sept 2026
Lake Wappapello
8005 Missouri 172 Williamsville MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions Poplar Bluff History Museum and North Main Street Historic District are located ...
9.4/10 Exceptional! (6 reviews)
"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from ..."
Reviewed on 9 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Southeast Missouri hotel availability
Stay near popular Southeast Missouri attractions
Things to do
Night Ghost Tour of Pythian Castle in Springfield Missouri
£15
per adult
96% of travellers recommend
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- Rustic River Cabin Getaway
- B&B in Black
- Bloomsdale Suite at Baetje Farms
- Adults Only Resorts & in Cape Girardeau
- “Brickyard”
- The Riverview
- Tru By Hilton Cape Girardeau
- Doe Run Hotels
- Current River Cottage
- Doniphan Hotels
- Ellington Hotels
- Hogan’s Hideout Bonnie Manor
- Crown Pointe Lodge
- High Hope Tree House #1 @Spring Lake Ranch
- ❤️ THE MAGIC TIPI RETREAT
- Farmington Hotels
- Fredericktown Hotels
- Postcard Cabins St Francois
- Glen Allen Hotels
- Hotels near Johnson's Shut-ins State Park
- Junction City Hotels
- Black River Motel and Restaurant
- Gay-Friendly Hotels in Lesterville
- Wilderness Lodge
- Lithium Hotels
- Middle Brook Hotels
- New Offenburg Hotels
- Urban Lofts
- Dancing Under Red Skies Tree House @Spring Lake
- Potosi Hotels
- Dexter Inn
- Drury Plaza Hotel Cape Girardeau Conference Center
- Fairfield Inn & Suites by Marriott Sikeston
- Hampton Inn Sikeston
- The cabin in Eden
- Towneplace Suites by Marriott Sikeston
- Travel Inn & Suites
- Sikeston Hotels
- Hotels with Connecting Rooms in Southeast Missouri
- Pet-Friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Hotels near Southeast Missouri State University
- Peaceful 4BR ranch w/ hot tub
- Silo Farm Haus
- 1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi
- Winona Hotels
- Flights to Bonne Terre
- Flights to Cape Girardeau
- Flights to Desloge
- Flights to Park Hills
- Flights to Wappapello
- Flights from Cape Girardeau Municipal
- Flights from Ste Genevieve
- Flights from Black
- Flights from Lesterville
- Flights from Dexter
- Flights from Viburnum
- Flights from Bonne Terre
- Flights from Arcadia
- Flights from London (LHR) to Cape Girardeau (CGI)
