Sikeston Travel Guide

Tourist Guide

Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri
Pre-teen girl walking through corn maze during fall
Columns and Dogwood Trees. Columns from an old church surrounded by colorful dog wood trees in full bloom
Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is £94 per night from 12 May to 13 May
£94
12 May - 13 May
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,007 reviews)
Clean room, everyone helpful and pleasant.

Reviewed on 27 Apr 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is £88 per night from 17 May to 18 May
£88
17 May - 18 May
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (551 reviews)
Burn outsin parking lot at 2 in morning. No excuses

Reviewed on 26 Apr 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is £67 per night from 20 May to 21 May
£67
20 May - 21 May
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,000 reviews)
Bathroom had pee stains around the toilet. On their add they use a picture of a large beautiful room where you check in. Not This motel is old and run down.

Reviewed on 22 Apr 2026

Best Western Plus Sikeston I-55
See all 300 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
New cabin in the woods with private hot tub

New cabin in the woods with private hot tub

Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffee maker and air conditioning. Popular attractions StarView Vineyards and King Neptune Memorial are ...
10/10 Exceptional! (145 reviews)
Cabin was nice and secluded, I didn’t realize there was no WiFi, but we figured it out. Everything else was wonderful!

Reviewed on 8 Apr 2026

New cabin in the woods with private hot tub
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
Stay at this cabin in Alexander County. Enjoy an in-room coffee maker and air conditioning.
Peaceful secluded cabin located near Horseshoe Lake
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna IL
Stay at this cabin in Anna. Enjoy a garden, patios and cable/satellite TV service. Our guests praise the helpful staff and the property condition in their reviews. ...
10/10 Exceptional! (409 reviews)
Everything we needed for a relaxing long weekend. Clean and in a quiet area.

Reviewed on 14 Apr 2026

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
See all properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions

Sikeston Depot Museum

3.8/5 (57 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
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