Title: Sikeston Travel Guide: Best of Sikeston, Missouri Travel 2026 | Expedia.co.uk [Hotels in Sikeston](https://expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Holiday Rentals in Sikeston](https://expedia.co.uk/Sikeston-Holiday-Rentals.d6058766.Travel-Guide-HolidayRentals)[Sikeston Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sikeston.d6058766.Car-Hire-Guide)[Sikeston Holidays](https://expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) # Sikeston Travel Guide ## Tourist Guide ![Photo by Ryan Coleman](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Ryan Coleman](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg) ## Visit Sikeston Things to do - Top hotels in Sikeston - Top Holiday Rentals in Sikeston ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO £80 28 Dec - 29 Dec includes taxes & fees Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ... 8.8/10 Excellent! (442 reviews) Yes Reviewed on 10 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=25178175&PinnedHotelID=25178175&HadPinnedHotel=true®ionId=6058766) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO £77 17 Dec - 18 Dec includes taxes & fees Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 9.4/10 Exceptional! (1,003 reviews) Clean room and spacious Reviewed on 8 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F12%2F2025&endDate=18%2F12%2F2025&selected=24210&PinnedHotelID=24210&HadPinnedHotel=true®ionId=6058766) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 100 Matthews Lane Sikeston MO £47 14 Dec - 15 Dec includes taxes & fees Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ... 8.4/10 Very Good! (716 reviews) Travel friendly accommodations at a good price. Facility was clean and functional as a halfway stopping point on the way home after Thanksgiving. Pet friendly option is a big plus for us. Recommended! Reviewed on 30 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=14%2F12%2F2025&endDate=15%2F12%2F2025&selected=34745&PinnedHotelID=34745&HadPinnedHotel=true®ionId=6058766) [See all 285 properties in Sikeston](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=14%2F12%2F2025&endDate=15%2F12%2F2025®ionId=6058766) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![On the Shawnee Wine Trail](https://images.trvl-media.com/lodging/38000000/37860000/37859700/37859643/2ab3c3a0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### On the Shawnee Wine Trail Carbondale IL Stay at this cabin in Carbondale. Enjoy patios, cable/satellite TV service and an in-room coffee maker. Popular attractions Cave Hollow Trailhead and Von Jakob ... 9.8/10 Exceptional! (229 reviews) The place was great, we really enjoyed our time here. It was exactly what we wanted. It was very clean and cozy and the fireplace definitely warms the place up! We appreciated the secluded and quiet atmosphere and the proximity to wineries and the Shawnee Forest. The biggest issue that makes us not ... Reviewed on 26 Nov 2025 [](https://expedia.co.uk/Carbondale-Hotels-On-The-Shawnee-Wine-Trail.h37859643.Hotel-Information) ![Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery ](https://images.trvl-media.com/lodging/75000000/74270000/74269700/74269659/47c539a2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery Cobden IL Stay at this cabin in Anna. Enjoy patios, an in-room coffee maker and in-room fireplaces. Popular attractions StarView Vineyards and King Neptune Memorial are ... 9.8/10 Exceptional! (150 reviews) Perfect little getaway! Thanks!! Reviewed on 29 Oct 2025 [](https://expedia.co.uk/Anna-Hotels-Brand-New-Cabin-In-The-Woods-With-Hot-Tub-12-Mile-From-Starview-Winery.h74269659.Hotel-Information) ![Exquisite views of Shawnee National Forest seen from a private, covered hot tub.](https://images.trvl-media.com/lodging/90000000/89650000/89641100/89641032/81921ef6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Exquisite views of Shawnee National Forest seen from a private, covered hot tub. Cobden IL Stay at this cabin in Cobden. Enjoy free Wi-Fi, a garden and patios. Popular attractions Peachbarn Winery and Von Jakob Winery & Brewery are located nearby. 9.8/10 Exceptional! (41 reviews) View from the cabin was indeed exquisite!! A very comfy quiet and private cabin for us and our baby. Well equipped and cozy rooms, kitchen, bathrooms. Fabulous hot tub! 15 minutes to Giant City State Park. We recommend Giant City Nature Trail & Rocky Bluff Trail easy and beautiful. Reviewed on 14 Nov 2025 [](https://expedia.co.uk/Cobden-Hotels-Exquisite-Views-Of-Shawnee-National-Forest-Seen-From-A-Private.h89641032.Hotel-Information) [See all properties in Sikeston](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6058766&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Sikeston hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2025-12-13&endDate=2025-12-14)[13 Dec - 14 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2025-12-13&endDate=2025-12-14) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2025-12-14&endDate=2025-12-15)[14 Dec - 15 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2025-12-14&endDate=2025-12-15) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025)[19 Dec - 21 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025) ### Popular places to visit #### City of Miner Convention Center Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savour the top-notch restaurants. [](https://expedia.co.uk/City-Of-Miner-Convention-Center-Sikeston.d818566100963352576.Attraction) #### Central Park Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this relaxing area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Central-Park-Sikeston.d6305608.Attraction) #### Sikeston Depot Museum You can spend time studying the exhibits at Sikeston Depot Museum during your travels in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants. 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