Sikeston Travel Guide

Tourist Guide

A tree with sunlight filtering through its leaves, creating a warm glow.
A person walking through a cornfield.
A building with three tall chimneys, surrounded by blooming trees with pink and white flowers.
A sign for Lambert's, a place of worship.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is £81 per night from 1 Nov to 2 Nov
£81
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is £57 per night from 1 Nov to 2 Nov
£57
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is £81 per night from 22 Nov to 23 Nov
£81
22 Nov - 23 Nov
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (649 reviews)
"Great hotel, clean spacious room, good breakfast choice"

Reviewed on 22 Oct 2026

Hampton Inn Sikeston
See all 318 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna IL
Stay at this cabin in Anna. Enjoy a garden, patios and cable/satellite TV service. Our guests praise the helpful staff and the property condition in their reviews. ...
10/10 Exceptional! (431 reviews)
"Very nice and clean"

Reviewed on 14 Oct 2026

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

Makanda IL
Stay at this golf cabin in Makanda. Enjoy free Wi-Fi, a garden and patios. Popular attractions Stone Creek Golf Club and Resort and Makanda Boardwalk are located ...
9.8/10 Exceptional! (78 reviews)
"Absolutely flawless from beginning to end I will definitely be returning"

Reviewed on 5 Oct 2026

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

Cape Girardeau MO
Stay at this holiday home in Cape Girardeau. Enjoy free Wi-Fi, laundry facilities and an in-room coffee maker. Popular attractions Show Me Center and Century ...
9.8/10 Exceptional! (38 reviews)
"We had a wonderful experience. Our host took good care of us, was responsive and pleasant. It's a beautiful home. Seems like a wonderful neighborhood. Close to some great food and the college. Would stay again."

Reviewed on 18 Oct 2026

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
See all properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions

Sikeston Depot Museum

7.6/10 (57 reviews)
You can spend time studying the exhibits at Sikeston Depot Museum during your travels in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Other places like Sikeston

Explore a world of travel with Expedia