Title: TOP Adults Only Resorts & Hotels in Cape Girardeau, MO for 2026 | Expedia.co.uk [Hotels in Cape Girardeau](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)[Holiday Rentals in Cape Girardeau](https://expedia.co.uk/Cape-Girardeau-Holiday-Rentals.d820.Travel-Guide-HolidayRentals)[Flights to Cape Girardeau](https://expedia.co.uk/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights)[Cape Girardeau Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau.d820.Car-Hire-Guide)[Cape Girardeau Holidays](https://expedia.co.uk/Cape-Girardeau.d820.Holidays-City-Breaks) ![Beautiful city by the Mississippi River](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Alice Burghart ![](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cape Girardeau Adults Only Resorts & Hotels Tonight [23 Feb - 24 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [24 Feb - 25 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-02-24&endDate=2026-02-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) No exact matches found, but these alternatives could be just right ## Recommended hotels in Cape Girardeau ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jackpot Suite | Living area | LED TV, Netflix, Hulu, first-run films](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (511 reviews) "The room was clean and I was able to check in a bit early." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara £74 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1,008 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly £84 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (111 reviews) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas £82 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (159 reviews) "Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard £78 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/0c802aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/60c56f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/860b4de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/5f66921b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Secluded Getaway Cabin within minutes of amenities [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Charming-Getaway-Cabin.h75891457.Hotel-Information) Cape girardeau 10/10 Exceptional (18 reviews) "We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy M. £214 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Charming-Getaway-Cabin.h75891457.Hotel-Information) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/dba6fd48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible (Tub) | Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/86c003aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/fe0d924e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,005 reviews) "The staff were all very friendly. The room was clean and the beds were nice. Bathroom was very clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fred £60 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible (Sofa Sleeper, Tub, 2 Rooms) | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/0f190cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,007 reviews) "Awesome stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breckin £75 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fd5c34e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/7794c781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a236a8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) Cape Girardeau 10/10 Exceptional (19 reviews) "My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim £118 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature) | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/182edc95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,004 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex £76 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/3867ac72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) Cape Girardeau 8.4/10 Very good (50 reviews) "Cozy and perfect for a couple. Great communication with the host" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth G. £78 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11®ionId=820&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_820) ## Find out more about Cape Girardeau ### Discover top Cape Girardeau attractions Cape Girardeau, Missouri, offers a delightful blend of culture, history, and outdoor adventure perfect for discerning travellers. Start your exploration at the Cape Riverfront, where you can stroll along the scenic riverwalk, enjoy local art installations, and soak in stunning views of the Mississippi River. Just a short distance away, the Cape Girardeau Conservation Nature Center invites families to connect with nature through interactive exhibits and beautiful trails, making it a fantastic spot for both children and adults to enjoy the great outdoors. For history enthusiasts, the Southeast Missouri Museum showcases the region's rich heritage with engaging displays and collections that are sure to captivate visitors. Don't miss the opportunity to experience the vibrant arts scene at the Arts Council of Southeast Missouri, which frequently hosts exhibits and events featuring local artists. Finally, for a dose of family fun, the Discovery Playhouse offers an engaging, hands-on environment for younger children to explore and learn. When it comes to accommodation, consider staying near the bustling downtown area, where charming hotels provide convenient access to these attractions, ensuring a relaxing base from which to explore. Many hotels in this area boast modern amenities and attentive service, creating an inviting atmosphere for families seeking both comfort and value. ## Top Cape Girardeau Hotel Reviews ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Allenville Hotels ](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Arnold ](https://www.expedia.co.uk/Arnold-Hotels-Gay-Friendly-Hotel.0-0-d177608-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Arnold ](https://www.expedia.co.uk/Arnold-Hotels-Hotels-With-Pool.0-0-d177608-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Spa Hotels in Arnold ](https://www.expedia.co.uk/Arnold-Hotels-Spa-Hotels.0-0-d177608-tSpaHotels.Travel-Guide-Filter-Hotels) - [Benton Hotels ](https://www.expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bernie Hotels ](https://www.expedia.co.uk/Bernie-Hotels.d3000349284.Travel-Guide-Hotels) - [Bertrand Hotels ](https://www.expedia.co.uk/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels ](https://www.expedia.co.uk/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomfield Hotels ](https://www.expedia.co.uk/Bloomfield-Hotels.d6351829.Travel-Guide-Hotels) - [Canalou Hotels ](https://www.expedia.co.uk/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Catron Hotels ](https://www.expedia.co.uk/Catron-Hotels.d3000349317.Travel-Guide-Hotels) - [Charleston Hotels ](https://www.expedia.co.uk/Charleston-Hotels.d7182.Travel-Guide-Hotels) - [Dexter Hotels ](https://www.expedia.co.uk/Dexter-Hotels.d55097.Travel-Guide-Hotels) - [Boutique Hotels in Downtown St. Louis ](https://www.expedia.co.uk/Downtown-St-Louis-St-Louis-Hotels-Boutique-Hotel.0-n800136-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Downtown St. Louis ](https://www.expedia.co.uk/Downtown-St-Louis-St-Louis-Hotels-Historic-Hotel.0-n800136-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Downtown St. Louis ](https://www.expedia.co.uk/Downtown-St-Louis-St-Louis-Hotels-Hotels-With-Indoor-Pools.0-n800136-0-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [East Prairie Hotels ](https://www.expedia.co.uk/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels) - [Wedding Hotels in Fenton ](https://www.expedia.co.uk/Fenton-Hotels-Wedding-Hotel.0-0-d7150-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Fredericktown Hotels ](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels) - [Friedheim Hotels ](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Glen Allen Hotels ](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Hayti ](https://www.expedia.co.uk/Hayti-Hotels-Gay-Friendly-Hotel.0-0-d6058765-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Jackson Hotels ](https://www.expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Junction City Hotels ](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Lemay ](https://www.expedia.co.uk/Lemay-Hotels-Gay-Friendly-Hotel.0-0-d3000008297-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Lesterville ](https://www.expedia.co.uk/Lesterville-Hotels-Gay-Friendly-Hotel.0-0-d3000445174-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Marble Hill Hotels ](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Marquand Hotels ](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels) - [Hotels with Restaurant in Marston ](https://www.expedia.co.uk/Marston-Hotels-Hotel-With-Restaurant.0-0-d55824-thotelwithrestaurant.Travel-Guide-Filter-Hotels) - [Miner Hotels ](https://www.expedia.co.uk/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Morehouse Hotels ](https://www.expedia.co.uk/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [New Madrid Hotels ](https://www.expedia.co.uk/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) - [Oran Hotels ](https://www.expedia.co.uk/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Perryville Hotels ](https://www.expedia.co.uk/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Poplar Bluff ](https://www.expedia.co.uk/Poplar-Bluff-Hotels-Gay-Friendly-Hotel.0-0-d9449-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Sedgewickville Hotels ](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Sikeston ](https://www.expedia.co.uk/Sikeston-Hotels-Gay-Friendly-Hotel.0-0-d6058766-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Sikeston ](https://www.expedia.co.uk/Sikeston-Hotels-Hotels-With-Indoor-Pools.0-0-d6058766-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Sikeston Hotels ](https://www.expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Resorts in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotel-Resorts.d6058763-aaHotelResorts.Travel-Guide-Accommodation) - [Golf Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Golf-Hotels.0-0-d6058763-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotel-With-Connecting-Rooms.0-0-d6058763-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotels-With-Smoking-Rooms.0-0-d6058763-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-La-Quinta-Inn-Suites.0-0-d6058763--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Luxury-Hotel.0-0-d6058763-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Pet-Friendly-Hotel.0-0-d6058763-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Romantic-Hotel.0-0-d6058763-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Spa-Hotels.0-0-d6058763-tSpaHotels.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University ](https://www.expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Adults-Only-Resorts.0-0-d178309-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Boutique Hotels in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Boutique-Hotel.0-0-d178309-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Budget-Hotels.0-0-d178309-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Family-Friendly-Hotel.0-0-d178309-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Gay-Friendly-Hotel.0-0-d178309-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Waterslides in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Hotels-With-Waterslides.0-0-d178309-tHotelswithWaterslides.Travel-Guide-Filter-Hotels) - [Luxury Hotels in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Luxury-Hotel.0-0-d178309-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Romantic-Hotel.0-0-d178309-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Hotels with Waterpark in St. Louis ](https://www.expedia.co.uk/St-Louis-Hotels-Waterpark-Hotel.0-0-d178309-twaterparkhotel.Travel-Guide-Filter-Hotels) - [St Mary Hotels ](https://www.expedia.co.uk/St-Mary-Hotels.d3000445480.Travel-Guide-Hotels) - [Wappapello Hotels ](https://www.expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels) - [Flights to Dexter ](https://www.expedia.co.uk/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights) - [Flights to Wappapello ](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights) - [Flights from Cape Girardeau Municipal ](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport) - [Flights from Sikeston Memorial Municipal ](https://www.expedia.co.uk/lp/airports/sik/flights-from-sikeston-memorial-municipal-airport) - [Flights from Bernie ](https://www.expedia.co.uk/lp/flights/3000349284/flights-from-bernie) - [Flights from Bertrand ](https://www.expedia.co.uk/lp/flights/3000349285/flights-from-bertrand) - [Flights from East Prairie ](https://www.expedia.co.uk/lp/flights/3000349349/flights-from-east-prairie) - [Flights from Dexter ](https://www.expedia.co.uk/lp/flights/55097/flights-from-dexter) - [Flights from Fredericktown ](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand ](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Altenburg ](https://www.expedia.co.uk/lp/flights/553248634983289075/flights-from-altenburg) - [Flights from Zalma ](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Frohna ](https://www.expedia.co.uk/lp/flights/553248634983521632/flights-from-frohna) - [Flights from Wyatt ](https://www.expedia.co.uk/lp/flights/553248634983534991/flights-from-wyatt) - [Flights from Scott City ](https://www.expedia.co.uk/lp/flights/553248634983544376/flights-from-scott-city) - [Flights from Jackson ](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson) - [Flights from Sikeston ](https://www.expedia.co.uk/lp/flights/6058766/flights-from-sikeston) - [Flights from Atlanta (ATL) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau) - [Flights from Birmingham (BHM) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau) - [Flights from Mumbai (BOM) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/bom/cgi/mumbai-to-cape-girardeau) - [Flights from Sedalia (DMO) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau) - [Flights from Dublin (DUB) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from London (LHR) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau) - [Flights from Lewiston (LWS) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau) - [Flights from Chicago (MDW) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau) - [Flights from Stow (MMN) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau) - [Flights from Pasco (PSC) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau) - [Flights from St. Louis (STL) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Tijuana (TIJ) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau) - [Bernie Holidays ](https://www.expedia.co.uk/Bernie.d3000349284.Holidays-City-Breaks) - [Dexter Holidays ](https://www.expedia.co.uk/Dexter.d55097.Holidays-City-Breaks) - [Visit Fredericktown ](https://www.expedia.co.uk/Fredericktown.dx55114) - [Visit New Madrid ](https://www.expedia.co.uk/New-Madrid.dx3000445315) - [Sikeston Holidays ](https://www.expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) - [Visit Sikeston ](https://www.expedia.co.uk/Sikeston.dx6058766) - [Rental cars Cape Girardeau Municipal airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide) - [Island Car Rentals Rental Cars in Cobalt ](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers) - [Redspot Rental Cars in Oran ](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers) - [Charleston Holiday Rentals ](https://www.expedia.co.uk/Charleston-Holiday-Rentals.d7182.Travel-Guide-HolidayRentals) - [Book Adults Only Resorts & Hotels in Cape Girardeau on Expedia.com ](https://www.expedia.com/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)