Title: Holiday Rentals Cape Girardeau from £84: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk

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![Aerial Photo of Cape Girardeau, Missouri, USA](https://images.trvl-media.com/place/820/34f5c59a-7e57-4244-94c6-c657830fc4ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[17 Jul - 19 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=820&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Cape Girardeau holiday rentals

![Interior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/0c802aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/0622af9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/860b4de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/60c56f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Secluded Getaway Cabin within minutes of amenities 

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Charming-Getaway-Cabin.h75891457.Hotel-Information)

Cape girardeau

10/10

Exceptional

(18 reviews)

"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy M.

£229

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Charming-Getaway-Cabin.h75891457.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/f432dafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/564d6e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/0e13dd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serenity South -- Gardens, River-Views, and Refreshing Space

[](https://www.expedia.co.uk/Sikeston-Hotels-Serenity-South-Gardens.h38940154.Hotel-Information)

Cape Girardeau

10/10

Exceptional

(152 reviews)

"Wonderful location! WonderfulStay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alison C.

£186

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Sikeston-Hotels-Serenity-South-Gardens.h38940154.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/469a5901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/6a739ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/a97a55c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/211494f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information)

Cape Girardeau

8.8/10

Excellent

(39 reviews)

"Will definitely book again! Great location, comfortable stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Pynktoria !.

£165

includes taxes & fees

30 Mar - 31 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information)

![TV, fireplace](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868642/2c8cc497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868642/8932b23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868642/673b3050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868642/bb974ed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gorgeous 1856 Log Cabin, Completely Renovated

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Gorgeous-1856-Log-Cabin.h112868642.Hotel-Information)

Jackson

10/10

Exceptional

(3 reviews)

"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chandler G.

£230

includes taxes & fees

1 Apr - 2 Apr

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Gorgeous-1856-Log-Cabin.h112868642.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/1c1368ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/0b3aaea0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/f4fbd89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/c5155680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Twisted Sassafras Treehouse 

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information)

Cape Girardeau

10/10

Exceptional

(32 reviews)

"Beautiful space indoors and out, can’t wait to come back when the weather allows more time for the outdoor amenities! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jordan R.

£227

includes taxes & fees

31 Mar - 1 Apr

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/3867ac72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Little Blue Cottage on Spanish

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

Cape Girardeau

8.2/10

Very good

(53 reviews)

"Cozy and perfect for a couple. Great communication with the host"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth G.

£84

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/w1440h810x0y3-bf19009e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video games, table football](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/a7fa16a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Games room](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/f1c736a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video games, table football](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/62582c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(8 reviews)

"Nice place, great times"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jace W.

£324

includes taxes & fees

30 Mar - 31 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information)

![1 bedroom, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868647/add99418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868647/94d9c4c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868647/b0435fb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868647/1862bab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Cottage, Rusted Route Farms

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Cottage.h112868647.Hotel-Information)

Jackson

10/10

Exceptional

(2 reviews)

"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Renee C.

£149

includes taxes & fees

30 Mar - 31 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Cottage.h112868647.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557550/68e05443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557550/b03fe6cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557550/a4370343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557550/b4eaf9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Modern 2BR Apt w Electric Fireplace By KeenStays

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Modern-2BR-Apt-W-Electric-Fireplace-By-KeenStays.h127557550.Hotel-Information)

Cape Girardeau

£156

includes taxes & fees

31 Mar - 1 Apr

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Modern-2BR-Apt-W-Electric-Fireplace-By-KeenStays.h127557550.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557548/e671b9f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557548/d5841e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557548/ae9b919f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557548/ada31fc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fresh & Cozy Retreat w/ King Bed · By KeenStays

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fresh-Cozy-Retreat-W-King-Bed-By-KeenStays.h127557548.Hotel-Information)

Cape Girardeau

£128

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fresh-Cozy-Retreat-W-King-Bed-By-KeenStays.h127557548.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557541/c4e4597e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557541/7f0c9c8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557541/112546bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/128000000/127560000/127557600/127557541/470e2ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Luxe-2KBR-Apt-W-Electric-Fireplace-By-KeenStays.h127557541.Hotel-Information)

Cape Girardeau

£157

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Luxe-2KBR-Apt-W-Electric-Fireplace-By-KeenStays.h127557541.Hotel-Information)

![Smart TV, fireplace, ping pong](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/9fd80641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/f8d3886b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/f5019574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/6b0091f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury 4BR Log Cabin Near SIU & Wine Trail

[](https://www.expedia.co.uk/Makanda-Hotels-Luxury-Log-Cabin-Near-SIU.h89781354.Hotel-Information)

Makanda

10/10

Exceptional

(47 reviews)

"Our group had a great time reuniting and visiting old haunts "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Keith P.

£395

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Makanda-Hotels-Luxury-Log-Cabin-Near-SIU.h89781354.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/09707f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/c221a56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/3f7db1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming cottage overlooking Lake Acre

[](https://www.expedia.co.uk/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information)

Dongola

10/10

Exceptional

(102 reviews)

"Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

carlton h.

£213

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/d22aee4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/b0f0a7b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/ded6701c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/2c1a0ed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rest, Relax and Renew. Our log cabin experience awaits your arrival. 

[](https://www.expedia.co.uk/Anna-Hotels-Rest.h31189922.Hotel-Information)

Anna

10/10

Exceptional

(407 reviews)

"Great location. Cozy cabin. Would stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jeffrey s

£152

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Anna-Hotels-Rest.h31189922.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/d70c82b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/73a1d2fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/1959f5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Rested Duck Mallard Room

[](https://www.expedia.co.uk/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information)

Olive Branch

9.4/10

Exceptional

(29 reviews)

"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

mike b.

£108

includes taxes & fees

30 Mar - 31 Mar

[](https://www.expedia.co.uk/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/3d5ec048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/60d7d429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/48434221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/853dbdda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

[](https://www.expedia.co.uk/Makanda-Hotels-3-Minutes-To-Giant-City-6-Minutes-To-SIU-4-Minutes-To-Shawnee-Winetrail.h88869111.Hotel-Information)

Makanda

9.8/10

Exceptional

(63 reviews)

"Stephen very friendly and accomadations excellent!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Walter H.

£146

includes taxes & fees

30 Mar - 31 Mar

[](https://www.expedia.co.uk/Makanda-Hotels-3-Minutes-To-Giant-City-6-Minutes-To-SIU-4-Minutes-To-Shawnee-Winetrail.h88869111.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/89000000/88930000/88928400/88928399/f8286145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/89000000/88930000/88928400/88928399/8a8ad86a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/89000000/88930000/88928400/88928399/4f18c4a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88930000/88928400/88928399/63184534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

[](https://www.expedia.co.uk/Makanda-Hotels-Winetrail-Cabin-SIU.h88928399.Hotel-Information)

Makanda

9.6/10

Exceptional

(44 reviews)

"Host was very welcoming and kind. All amenities included covered everything anyone would need. The cabin was spacious, clean and welcoming. Our little dog loved it too. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara M.

£170

includes taxes & fees

30 Mar - 31 Mar

[](https://www.expedia.co.uk/Makanda-Hotels-Winetrail-Cabin-SIU.h88928399.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/81000000/80800000/80794200/80794106/w691h683x160y0-35462827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/81000000/80800000/80794200/80794106/w693h683x174y0-32d2f409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/81000000/80800000/80794200/80794106/w675h683x175y0-bccaa29a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/81000000/80800000/80794200/80794106/w675h683x175y0-e472cb80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Relax in the country at Countryside Villas! - Villa A

[](https://www.expedia.co.uk/Jackson-Hotels-Relax-In-The-Country-At-Countryside-Villas.h80794106.Hotel-Information)

Jackson

10/10

Exceptional

(33 reviews)

"Great place to stay, felt like home away from home. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brittany

£137

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Jackson-Hotels-Relax-In-The-Country-At-Countryside-Villas.h80794106.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/05ba3853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/95950b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/05da8d7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/d3b8d0f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Contemporary Glamping with Native American Appeal

[](https://www.expedia.co.uk/Anna-Hotels-Contemporary-Glamping-With-Native-American-Appeal.h27145221.Hotel-Information)

Anna

9.8/10

Exceptional

(158 reviews)

"Every Th I was perfect close to the shopping we wanted to and such quiet area "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christina S.

£247

includes taxes & fees

20 Apr - 21 Apr

[](https://www.expedia.co.uk/Anna-Hotels-Contemporary-Glamping-With-Native-American-Appeal.h27145221.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/53db6388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, bed sheets](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/3bc4c831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/52fdc4c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/23c71fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy cabins on beautiful Horseshoe Lake

[](https://www.expedia.co.uk/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information)

Olive Branch

9.8/10

Exceptional

(37 reviews)

"The cabin was great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin G.

£108

includes taxes & fees

29 Mar - 30 Mar

[](https://www.expedia.co.uk/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-11&endDate=2026-04-12&regionId=820&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find holiday rentals that suit your style

Cabins

[](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America&regionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=CABIN)

Private holiday homes

[](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America&regionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America&regionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=APARTMENT)

Cottages

[](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau%2C+Missouri%2C+United+States+of+America&regionId=820&latLong=37.305884%2C-89.518148&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=COTTAGE)

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## Top Cape Girardeau Hotel Reviews

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"My wife and I stay was absolutely lovely. "

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"Easy check in, great view "

[](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"The hot tub was not hot enough but that was not on my list, it was suggested here. My complaint was, for seniors, there should be handrail installed to hold on to for stepping up and into the hot tub and getting out, it's very precarious as it is now. My second suggestion was people are not showering off, particularly kids when they get into the hot tub/pool and there were a huge amount of foam suds from people bodies. Something to remind people they should wash before entering? Maybe the answer could also be twioce a day cleaning of the hot tub?"

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg)

### Candlewood Suites Cape Girardeau by IHG

2/10 Terrible

"Booked reservation online with Expedia and when I get to the candle wood suites they turn me away saying they don't have any rooms available. Very inconvenient "

[](https://expedia.co.uk/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

![“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/1e923d10_y.jpg)

### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

10/10 Excellent

"House is an old relic and awesome. Very clean and very nice. Chip was super friendly and will stay again when I’m the area. "

[](https://expedia.co.uk/Cape-Girardeau-Hotels-Remodeled-1920s-Dutch-Colonial-Revival-In-Downtown-Cape-Girardeau.h76544096.Hotel-Information)

![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Great Staff! "

[](https://expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Serenity South -- Gardens, River-Views, and Refreshing Space](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/f432dafb_y.jpg)

### Serenity South -- Gardens, River-Views, and Refreshing Space

10/10 Excellent

"This is a beautiful, well-maintained historic home in a neat part of town -- walking distance to lots of attractions. The hospitality was off the charts. Every detail was thought out. Bed was comfortable, AC worked great, and wonderful spaces (dining room, living room, porch) to hang out in!"

[](https://expedia.co.uk/Sikeston-Hotels-Serenity-South-Gardens.h38940154.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed_y.jpg)

### Drury Inn & Suites Cape Girardeau

10/10 Excellent

"LOVED EVERYTHING ABOUT THIS PLACE"

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau](https://images.trvl-media.com/lodging/121000000/120670000/120661800/120661701/fa9f5d7f_y.jpg)

### 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

8/10 Good

"perfect for what we needed it for. would recommend this place."

[](https://expedia.co.uk/Cape-Girardeau-Hotels-3-Bedroom-3-Full-Bath-In-Beautiful-Historic-District-Downtown-Cape-Girardeau.h120661701.Hotel-Information)

## Find out more about Cape Girardeau

**Everything you need to know about** **Cape Girardeau** **holiday rentals**

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Cape Girardeau holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cape Girardeau holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Cape Girardeau holiday rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Cape Girardeau. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Cape Girardeau holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Cape Girardeau holiday rentals we have selected for you start as low as £84 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Cape Girardeau rentals**

At Expedia, we put the best Cape Girardeau holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Cape Girardeau rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cape Girardeau holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cape Girardeau. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

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## Frequently asked questions

### Can I find holiday rentals in Cape Girardeau?

### What are some of the best holiday rentals that Cape Girardeau has to offer?

### How many holiday rentals will I find in Cape Girardeau?

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