Most Popular Hotels in Sikeston

See all 27 Hotels in Sikeston
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Pear Tree Inn - Sikeston
Pear Tree Inn - Sikeston

2602 E Malone Avenue, Sikeston 63801

2.5 out of 5.0
4.3 out of 5 (327 reviews)

Located in the heart of Sikeston, this hotel is 0.2 mi (0.3 km) from The Book Bug and 3.1 mi (5 km) from Sikeston Depot Museu …

£68
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Sikeston 63801

3.0 out of 5.0
4.7 out of 5 (323 reviews)

Located in the heart of Sikeston, this hotel is 0.2 mi (0.3 km) from The Book Bug and within 6 mi (10 km) of Sikeston Depot …

£90
Comfort Inn And Suites
Comfort Inn And Suites

109 Matthews Ln, Sikeston 63801

2.5 out of 5.0
4.2 out of 5 (40 reviews)

Located in the heart of Sikeston, this hotel is 0.6 mi (0.9 km) from The Book Bug and within 6 mi (10 km) of Sikeston Depot …

£72
Super 8 Charleston MO
Super 8 Charleston MO

310 S Story St, Charleston 63834

2.0 out of 5.0
3.5 out of 5 (103 reviews)

Located in the heart of Charleston, this motel is within 20 mi (32 km) of Fort Defiance, The Book Bug, and Mound City Nationa …

£41
Quality Inn Charleston
Quality Inn Charleston

102 Drake St, Charleston 63834

2.5 out of 5.0
3.8 out of 5 (59 reviews)

Situated in Charleston, this hotel is within 16 mi (25 km) of The Book Bug, Central Park, and Fort Defiance. Sikeston Depot …

£62
Super 8 - Sikeston/Miner Area
Super 8 - Sikeston/Miner Area

2609 E Malone Ave, Sikeston 63801

2.0 out of 5.0
3 out of 5 (172 reviews)

Situated in Sikeston, this hotel is 0.2 mi (0.4 km) from The Book Bug and within 3 mi (5 km) of Sikeston Depot Museum and Boo …

£48
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau

2904 Old Orchard Rd, Jackson 63755

2.5 out of 5.0
4.3 out of 5 (238 reviews)

Located in the heart of Jackson, this hotel is within 3 mi (5 km) of Cape Girardeau Conservation Nature Center, Lazy L Safari …

£59
Americas Best Value Inn & Suites Sikeston
Americas Best Value Inn & Suites Sikeston

220 S Interstate Dr, Sikeston 63801

2.0 out of 5.0
3.7 out of 5 (182 reviews)

This family-friendly Sikeston hotel is located in a rural location, 1 mi (1.6 km) from The Book Bug, and within 6 mi (10 km …

£51
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO

225 Drury Lane, Jackson 63755

3.0 out of 5.0
4.7 out of 5 (221 reviews)

Located in the heart of Jackson, this hotel is within 6 mi (10 km) of Steele Crest Winery, Lazy L Safari Park, and Litz Park. …

£76
Holiday Inn Express & Suites Sikeston Southwest
Holiday Inn Express & Suites Sikeston Southwest

115 Hospitality Dr, Sikeston 63801

2.5 out of 5.0
4.3 out of 5 (44 reviews)

Situated in a rural location, this hotel is 1 mi (1.7 km) from Central Park and 1.4 mi (2.3 km) from Sikeston Depot Museum. …

£97

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