Title: Cheap Flights to Sikeston - Expedia.co.uk ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £351 Cheap Flights to Sikeston [View £351 flight on Wed, 18 Mar 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:LHR,to:STL,departure:18/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:350.65&airProductToken=AQplCjEIzJABEgM5MjEY64kBIKUEKOb2hwMwxfeHAzhLQABYAWoFRUxUMDByCEtKT0lLWEJRCjAIzJABEgM0NDgYpQQg8lwoqfiHAzCL_YcDOEtAAFgBagVFTFQwMHIIS0pPSUtYQlESCggBEAEYASoCTEgYASIECAEQASgCKAMoBDAL) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Sikeston Travel Guide](https://expedia.co.uk/Sikeston.dx6058766)[Hotels in Sikeston](https://expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Sikeston Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sikeston.d6058766.Car-Hire-Guide)[Sikeston Holidays](https://expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) ## Popular airlines to Sikeston - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) - ![Air Canada](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AC.svg) Air Canada [](https://www.expedia.co.uk/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:29/01/2026TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AC"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to Sikeston Prices were available within the past 7 days and start at £351 for one-way flights and £447 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Sat, 7 Mar - Wed, 18 Mar LHR London STL St. Louis £447 Return just found [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:STL,departure:07/03/2026TANYT&leg2=from:STL,to:LHR,departure:18/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:446.55&airProductToken=AQquAQo1CMyQARIEMjQ4NRjriQEgjBUoi_uGAzD5-4YDOEtAAFgBaghFQ09MSUdIVHIIS0RWUUFYQlEKMwjMkAESAzQzNBiMFSCuHCjm_oYDMLmDhwM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUQpACMyQARIENzgyNhiuHCDyXCikhIcDMP2EhwM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUXoKCNWCARIENzgyNgqHAQpBCM-mARIENzc1MBjyXCDEjQEovPuHAzDT_IcDOEtAAFgBaghFQ09MSUdIVHIIS0RWUUFYQlF6CgjVggESBDc3NTAKQgjPpgESBDc3OTQYxI0BIOuJASjE_ocDMPyBiAM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUXoKCNWCARIENzc5NBIKCAIQARgCKgJMSBgBIgQIARABKAIoAygEMAs) ![Brussels Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SN.gif) Wed, 11 Mar - Wed, 25 Mar LHR London STL St. Louis £454 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:STL,departure:11/03/2026TANYT&leg2=from:STL,to:LHR,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:453.25&airProductToken=AQq9AQo2CNOcARIEMjEwNBjriQEgoaQBKJqohwMw26iHAzhLQABYAWoIRUNPTElHSFRyCEtEVlFBWEJRCkEI05wBEgQ4ODAxGKGkASCIGCiPqocDMJeuhwM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUXoKCNWCARIEODgwMQpACNOcARIEOTAxMhiIGCDyXCiPr4cDMK2whwM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUXoKCNWCARIEOTAxMgprCjMIzJABEgM0NDkY8lwgpQQo3syIAzDm0IgDOEtAAFgBaghFQ09MSUdIVHIIS0RWUUFYQlEKNAjMkAESAzkwMhilBCDriQEoxdGIAzCp0ogDOEtAAVgBaghFQ09MSUdIVHIIS0RWUUFYQlESCggCEAEYAioCU04YASIECAEQASgCKAMoBDAL) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, 26 Jan - Tue, 3 Feb LHR London STL St. Louis £460 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:STL,departure:26/01/2026TANYT&leg2=from:STL,to:LHR,departure:03/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:459.65&airProductToken=AQq9AQpBCNWCARIEOTc1NxjriQEguTwo1buDAzC5vIMDOEtAAFgBaghFQ09CQVNJQ3IIS0RWUUtYQlF6CgjMsAESBDk3NTcKQQjVggESBDk3NDgYuTwgxI0BKM-9gwMw-sGDAzhLQAFYAWoIRUNPQkFTSUNyCEtEVlFLWEJRegoIzLABEgQ5NzQ4CjUI1YIBEgQzNDY4GMSNASDyXCjRwoMDMIfEgwM4S0ABWAFqCEVDT0JBU0lDcghLRFZRS1hCUQqtAQo0CNWCARIENDQ1NBjyXCCIGCjkmIQDMOeZhAM4S0AAWAFqCEVDT0JBU0lDcghLRFZRS1hCUQoyCNWCARICNTIYiBgguTwowZqEAzCwnoQDOEtAAVgBaghFQ09CQVNJQ3IIS0RWUUtYQlEKQQjVggESBDk3NTgYuTwg64kBKMufhAMww6CEAzhLQAFYAWoIRUNPQkFTSUNyCEtEVlFLWEJRegoIzLABEgQ5NzU4EgoIARABGAEqAlVBGAEiBAgBEAEoAigDKAQwAQ) ![Austrian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/OS.gif) Tue, 8 Sept - Fri, 18 Sept LHR London STL St. Louis £462 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:STL,departure:08/09/2026TANYT&leg2=from:STL,to:LHR,departure:18/09/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:461.65&airProductToken=AQqsAQo0CM-mARIDMzQwGOuJASCVIijMm5cDMM6clwM4S0AAWAFqCEVDT0xJR0hUcghLRFZRQVhCUQoyCM-mARICNDUYlSIgrhwonp2XAzDsoZcDOEtAAVgBaghFQ09MSUdIVHIIS0RWUUFYQlEKQAjPpgESBDc3MzUYrhwg8lwo06KXAzCmo5cDOEtAAVgBaghFQ09MSUdIVHIIS0RWUUFYQlF6CgjVggESBDc3MzUKawozCMyQARIDNDQ5GPJcIKUEKK6TmAMwxZeYAzhLQABYAWoIRUNPTElHSFRyCEtEVlFBWEJRCjQIzJABEgM5MTQYpQQg64kBKMibmAMwrJyYAzhLQAFYAWoIRUNPTElHSFRyCEtEVlFBWEJREgoIAhABGAIqAk9TGAEiBAgBEAEoAigDKAQwCw) ![Swiss International Air Lines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LX.gif) Tue, 3 Mar - Mon, 9 Mar LGW London STL St. Louis £465 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LGW,to:STL,departure:03/03/2026TANYT&leg2=from:STL,to:LGW,departure:09/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:464.98&airProductToken=AQqwAQo0CMywARIDNDMzGMuxASC5PCjg04YDMMnUhgM4S0AAWAFqCEVDT0xJR0hUcghLRFZRS1hCUQpBCMywARIENDY0MBi5PCCYzgEohNyGAzCW4IYDOEtAAVgBaghFQ09MSUdIVHIIS0RWUUtYQlF6CgjBhgESBDQ2NDAKNQjBhgESBDg5NjkYmM4BIPJcKLTqhgMwyeuGAzhLQAFYAWoIRUNPTElHSFRyCEtEVlFLWEJRCpoBCjIIwYYBEgQ4OTcwGPJcIJjOASixmIcDMKqZhwM4S0AAWAFqBUJBU0lDcghLRFZRS1hCUQoxCMGGARIDODgwGJjOASC5PCi1mocDMJWehwM4S0ABWAFqBUJBU0lDcghLRFZRS1hCUQoxCMywARIDNDMyGLk8IMuxASiloYcDMI6ihwM4S0ABWAFqBUJBU0lDcghLRFZRS1hCURIKCAEQARgBKgJBQxgBIgQIARABKAIoAygEMAE) ## Find the cheapest month to fly from Columbus (CMH) to St. Louis (STL) ### October is typically the cheapest month to fly From £104 - £339 per traveller. ## Expedia flights to Sikeston Searching for cheap flights to Sikeston? No travel company presents more choices than Expedia if you're looking to compare flights to Sikeston. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Missouri. Expedia provides the cheapest flights to many destinations in Missouri and you may find even greater savings if you combine your flight with a hotel stay in Sikeston. Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast. Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Sikeston for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Sikeston flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price. ## Frequently asked questions ### What is the name of Sikeston's airport? ### What airport is best to fly into Sikeston? ### How many airlines fly to Sikeston? ### Which airlines fly to Sikeston? ### How many nonstop flights are there to Sikeston? ### Where are the most popular flights to Sikeston departing from? ### How long is the flight to Sikeston Airport? ### How to book the cheapest flight to Sikeston? ### Do you have any tips for my flight to Sikeston? > - The secret to having an amazing flight experience is to pack ahead. Start with the essentials: passport, boarding pass, cash and important medications. Next, bring items that'll help keep you occupied, like some electronic gadgets or a thrilling novel. You'll also want to bring your chargers, a comfy neck pillow and a pair of headphones. Finally, be sure to toss in toiletries like a toothbrush, deodorant and a fresh change of clothes. > > > Do not pack the following items in your hand luggage: > > > - While the list of restricted items can differ between airlines, the general rule to follow is avoid carrying anything flammable, sharp or explosive. This includes things like screwdrivers, blades, spray paint and flares. Sporting equipment like baseball bats, and objects that could harm other people, such as firearms and ammunition, won't be allowed on board either. > > > What to wear on a flight: > > > - Your aim here is to feel as comfortable as possible. Pick shoes that are easy to pull on and off, dress in loose, breathable clothing and don't forget to bring a pullover in case you get cold in the cabin. > - Most travellers are aware of deep vein thrombosis (DVT), a blood clot condition caused by long periods of sitting. To minimize your risk on board, stay hydrated, consider wearing compression tights or socks and keep your feet and legs moving. ### How to get through airport security fast when flying to Sikeston? > - First things first. Your ID and travel documents will need to be presented to airport security. Keep them within easy reach to avoid fumbling around for them. > - Next up, both you and your hand luggage must be X-rayed. To make the process quick and painless, take off anything that is likely to set the alarm off. Items like your coat, belt and headphones will be required to go through the machine. > - For just a few minutes, you'll have to unplug from technology. Your phone, tablet and any other electronic gadgets will need to be sent through the scanner. > - Any liquids or gels, such as toothpaste or perfume, that you want to take on board need to be in containers no greater than 3.4 ounces (100 millilitres). Also, everything must fit inside a quart-size (one litre), clear zip-close bag. > - It's also likely that you'll be required to take your shoes off to be X-rayed, so wearing slip-on sneakers is always a wise idea. > - Sharp items are prohibited in the cabin. They'll be confiscated at security, so pack them in your checked suitcase. __Flights to Sikeston information__ | Destination airport | Lambert-St. Louis Intl. | | ----------------------------- | ----------------------- | | Destination airport IATA code | STL | | Destination city name | St. Louis | | Return price | £447 | ## Trending flights to Sikeston Prices were available within the past 7 days and start at £351 for one-way flights and £447 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Sat, 7 Mar - Wed, 18 Mar LHR London STL St. Louis £447 Return just found [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:STL,departure:07/03/2026TANYT&leg2=from:STL,to:LHR,departure:18/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:446.55&airProductToken=AQquAQo1CMyQARIEMjQ4NRjriQEgjBUoi_uGAzD5-4YDOEtAAFgBaghFQ09MSUdIVHIIS0RWUUFYQlEKMwjMkAESAzQzNBiMFSCuHCjm_oYDMLmDhwM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUQpACMyQARIENzgyNhiuHCDyXCikhIcDMP2EhwM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUXoKCNWCARIENzgyNgqHAQpBCM-mARIENzc1MBjyXCDEjQEovPuHAzDT_IcDOEtAAFgBaghFQ09MSUdIVHIIS0RWUUFYQlF6CgjVggESBDc3NTAKQgjPpgESBDc3OTQYxI0BIOuJASjE_ocDMPyBiAM4S0ABWAFqCEVDT0xJR0hUcghLRFZRQVhCUXoKCNWCARIENzc5NBIKCAIQARgCKgJMSBgBIgQIARABKAIoAygEMAs) \*Available to Expedia members.