Title: 10 TOP Things to Do in Southeast Missouri September 2025 | Expedia.co.uk [Southeast Missouri Travel Guide](https://expedia.co.uk/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks) # What to do in Southeast Missouri, MO ## Activities, attractions and tours ## Visit Southeast Missouri Types of activities [Southeast Missouri travel guide](https://expedia.co.uk/Southeast-Missouri.dx6058763) ![Southeast Missouri](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Southeast Missouri](https://mediaim.expedia.com/destination/9/6c450e001334a84543e95019353aad53.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Southeast Missouri](https://mediaim.expedia.com/destination/9/a89308cd6725fa917758c794dd86c33d.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Photo by Jessica Richter](https://mediaim.expedia.com/destination/2/4ddf292149c3402549f16eb8c5528744.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Jessica Richter](https://mediaim.expedia.com/destination/2/4ddf292149c3402549f16eb8c5528744.jpg) ![Photo by Jessica Richter](https://mediaim.expedia.com/destination/2/71071bca60cf5af304b1d202a4f54f4d.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Jessica Richter](https://mediaim.expedia.com/destination/2/71071bca60cf5af304b1d202a4f54f4d.jpg) ## Southeast Missouri Attractions Let Expedia help you to experience the best that Southeast Missouri has to offer! If you’re planning a trip to Southeast Missouri, we can provide you with a list of the top sightseeing attractions, as well as helping you to find unmissable activities. Whether you’re travelling to Southeast Missouri with your family, planning a romantic trip with your loved one, or visiting on business, we’ll make it easy to plan an unforgettable holiday that checks all the boxes. #### Places of interest in Southeast Missouri Southeast Missouri is crammed with must-see places to visit and things to do. We can help you decide where to stay in Southeast Missouri, and make it a breeze to explore Southeast Missouri and the surrounding areas with our guides on where to go, what to see and when to see it. No matter how long your stay, it’s easy to find places of interest in Southeast Missouri to make sure that you enjoy your holiday to the fullest and don’t miss a thing. Leave the local knowledge to us and leave the hassle behind. If you’re planning a visit to Southeast Missouri, why not check out our handy guides to places of interest in the area? You can browse lists of things to do, learn about the most popular attractions, and get help with planning the details of your trip. Expedia makes it easy for you to check out all the top sights in Southeast Missouri. #### Southeast Missouri attractions Southeast Missouri has something for everyone, so whether you’re planning to get active on a summer holiday, put a spring in your step with a romantic rendezvous, or pamper yourself with a leisurely winter trip, you’ll find plenty of attractions in Southeast Missouri to keep you entertained. Expedia makes it easy to book your flight, hotel and rental car in advance, making for hassle-free travel and freeing you up to explore the sights of Southeast Missouri. Looking for things to do in Southeast Missouri can be time-consuming, but we can take the hassle out of planning your holiday. Whether you’re looking to get active in the great outdoors, sample the cuisine of Southeast Missouri or catch up with the vibrant local culture, our guides to Southeast Missouri attractions ensure that you’ll have a successful trip, whatever the season. Happy trails! * * * Explore thousands of activities with **free cancellation and no added fees**. Design your experience with airport transfers, excursions, day tours & more. Get an insider's look in what to book before you travel. * * * ## Recommended things to do in Southeast Missouri | Number of things to do | 32 | | --- | --- | | Cheapest thing to do on Expedia | [City centre St. Louis Smartphone Guided Audio Walking Tour App](https://expedia.co.uk/things-to-do/city-centre-st-louis-smartphone-guided-audio-walking-tour-app.a49595158.activity-details): £6 | | Top 5 things to do | - [St Louis: City Museum General Admission Ticket](https://expedia.co.uk/things-to-do/st-louis-city-museum-general-admission-ticket.a44567307.activity-details) - [St. Louis Narrated Trolley Tour](https://expedia.co.uk/things-to-do/90-minutes-st-louis-narrated-trolley-tour.a45948444.activity-details) - [St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour](https://expedia.co.uk/things-to-do/st-louis-gateway-ghouls-and-hauntings-walking-tour.a47668485.activity-details) - [St. Louis: Museum of Illusions Entry Ticket](https://expedia.co.uk/things-to-do/st-louis-museum-of-illusions-entry-ticket.a50485241.activity-details) - [Private Gastronomy Tour (BBQ Joints & Breweries) in St. Louis](https://expedia.co.uk/things-to-do/private-gastronomy-tour-bbq-joints-breweries-in-st-louis.a46594451.activity-details) | | Half-day tours | - [St. Louis Narrated Trolley Tour](https://expedia.co.uk/things-to-do/90-minutes-st-louis-narrated-trolley-tour.a45948444.activity-details) - [St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour](https://expedia.co.uk/things-to-do/st-louis-gateway-ghouls-and-hauntings-walking-tour.a47668485.activity-details) - [Lemp Haunted Area Walking Tour](https://expedia.co.uk/things-to-do/lemp-haunted-area-walking-tour.a1357747.activity-details) - [St. Louis Ghosts: Gateway Ghouls and Hauntings](https://expedia.co.uk/things-to-do/st-louis-night-time-dark-history-tour.a5257552.activity-details) - [The Haunted Lemp Brewery Bottle Works Tour](https://expedia.co.uk/things-to-do/the-haunted-lemp-brewery-bottle-works-tour.a47252948.activity-details) | | With kids | - [St Louis: City Museum General Admission Ticket](https://expedia.co.uk/things-to-do/st-louis-city-museum-general-admission-ticket.a44567307.activity-details) - [St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour](https://expedia.co.uk/things-to-do/st-louis-gateway-ghouls-and-hauntings-walking-tour.a47668485.activity-details) - [St. Louis: Museum of Illusions Entry Ticket](https://expedia.co.uk/things-to-do/st-louis-museum-of-illusions-entry-ticket.a50485241.activity-details) - [Lemp Haunted Area Walking Tour](https://expedia.co.uk/things-to-do/lemp-haunted-area-walking-tour.a1357747.activity-details) - [The Haunted Lemp Brewery Bottle Works Tour](https://expedia.co.uk/things-to-do/the-haunted-lemp-brewery-bottle-works-tour.a47252948.activity-details) | ## What to do in Southeast Missouri * * * ### Popular places to visit ![Elephant Rocks State Park](https://mediaim.expedia.com/destination/2/86e50eabc9d5592586815e7688be64ef.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Elephant Rocks State Park You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks. [](https://expedia.co.uk/Elephant-Rocks-State-Park-Ironton.d553248621532648464.Attraction) ![Rocky Falls](https://mediaim.expedia.com/destination/2/f2325d7f040c776e314b23ad9fbdb813.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rocky Falls Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting. [](https://expedia.co.uk/Rocky-Falls-Winona.d553248621532648456.Attraction) ![Lake Wappapello](https://mediaim.expedia.com/destination/2/a6135d9f1717ada26d9944dd5bb40459.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lake Wappapello Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants. [](https://expedia.co.uk/Lake-Wappapello-Wappapello.d553248621532648460.Attraction) #### Southeast Missouri State University Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Attraction) #### Century Casino Caruthersville Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants. [](https://expedia.co.uk/Lady-Luck-Casino-Caruthersville.d553248621532655201.Attraction) #### Current River State Park Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront. [](https://expedia.co.uk/Current-River-State-Park-Salem.d553248621532648450.Attraction) #### Alley Spring & Mill Learn about the local history of Eminence with a stop at Alley Spring & Mill. While you're in the area, stroll along the riverfront. [](https://expedia.co.uk/Alley-Spring-Mill-Eminence.d553248622784732024.Attraction) #### Clearwater Lake Commune with nature and explore the great outdoors at Clearwater Lake during your travels in Piedmont. [](https://expedia.co.uk/Clearwater-Lake-Piedmont.d553248635976197419.Attraction) #### Isle Casino Cape Girardeau Why not roll the dice with a visit to Isle Casino Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Attraction) * * * Looking for fun things to do nearby? Check [things to do near me](https://www.expedia.co.uk/things-to-do-near-me) to find and book the best things to do, fun activities, and top attractions wherever you happen to be. * * * ## Day trip destinations from Southeast Missouri ![Poplar Bluff](https://mediaim.expedia.com/destination/9/6c450e001334a84543e95019353aad53.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Poplar Bluff [](https://expedia.co.uk/Poplar-Bluff.dx9449) ![Photo by Summer Williams](https://mediaim.expedia.com/destination/2/f2491779cf462fb153bab34fde97528f.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Fredericktown [](https://expedia.co.uk/Fredericktown.dx55114) ![Photo by Alice Burghart](https://mediaim.expedia.com/destination/2/05bd52cb345646b3367dd8ecf4f9fbc5.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Bonne Terre [](https://expedia.co.uk/Bonne-Terre.dx55598) ![Potosi](https://mediaim.expedia.com/destination/1/289e2bbc5a7419969a643da96ef0071d.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Potosi [](https://expedia.co.uk/Potosi.dx181478) ![Photo by Karissa Krull](https://mediaim.expedia.com/destination/2/dcb48422dadbf0e83947b689e7b66af1.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Farmington [](https://expedia.co.uk/Farmington.dx6058764) ![Photo by Ryan Coleman](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Sikeston [](https://expedia.co.uk/Sikeston.dx6058766) ## Explore a world of travel with Expedia - 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