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Check availability on Southeast Missouri 3 Star Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Southeast Missouri 3-star hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Darnetta
£85
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

2. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Tim
£82
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Sikeston, MO
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.
A hotel room with two beds, a nightstand, a lamp, and a chair.

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
£66
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.
Pool
A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

4. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Nathan
£72
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Poplar Bluff by IHG
A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.
An indoor swimming pool with multiple lanes, surrounded by seating areas and tables.
Two grey armchairs with green cushions, a small side table with a white lamp, and wall-mounted sconces.
A hotel room with a brick wall, two beds, a desk with a TV, and a patterned carpet.

5. Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
Hayti
United States
Cynthia
£84
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Hayti Caruthersville
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
£86
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a reception desk, seating area, and large windows.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.
An indoor swimming pool with a clear view of the outside through large windows.

7. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
£80
includes taxes & fees
29 Oct - 30 Oct
Drury Inn & Suites Poplar Bluff
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A restaurant with a brick wall, a flat-screen TV, and a bar area.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

8. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Debra S
£64
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Jackson MO
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A spacious living room with a sofa set, a coffee table, and a dining area.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A lobby with seating areas, a reception desk, and a bar.

9. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
£107
includes taxes & fees
23 Oct - 24 Oct
Courtyard by Marriott Cape Girardeau Downtown
A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.
A modern hotel room with a large bed, a desk, a TV, and a balcony with a view.
A modern bathroom with a glass shower enclosure, a vanity with a mirror, and a towel rack.
A modern hotel room with a kitchen area, a dining space, and a living area with a view.

10. Century Casino & Hotel Caruthersville

Century Casino & Hotel Caruthersville
Caruthersville
United States
Jessica
£104
includes taxes & fees
13 Oct - 14 Oct
Century Casino & Hotel Caruthersville
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.
A corner market with a refrigerated display case and a pantry area.

11. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Nancy
£83
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites by Marriott Poplar Bluff
A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.
A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.
A swimming pool with lounge chairs and a view of the night sky.
A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.

12. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Festus
United States
Debra S
£73
includes taxes & fees
14 Oct - 15 Oct
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

13. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
£77
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Cape Girardeau
A hotel room with a large bed, a desk with a lamp, a television, and a bathroom visible in the background.
A multi-story hotel with a brick facade and large windows, featuring a parking lot in front.
A restaurant with multiple tables and chairs, a counter with a coffee machine, and framed pictures on the walls.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a potted plant.

14. Baymont by Wyndham Festus

Baymont by Wyndham Festus
Festus
United States
Gretchen
£53
additional charges may apply
1 Nov - 2 Nov
Baymont by Wyndham Festus
A red wooden mill with a small bridge over a flowing river, surrounded by lush greenery.
A dining area with a round table and chairs, large windows with curtains, and a whiteboard on the wall.
A row of yellow buildings with white railings and a covered front porch.
A playground with a slide, climbing structures, and a small shelter.

15. Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
Mountain View
United States
Joanne
£81
includes taxes & fees
13 Oct - 14 Oct
Honeysuckle Inn - Mountain View
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

16. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
£87
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites by Marriott Sikeston
A bedroom with a bed, a desk, and a chair. There is a window with curtains, a radiator, and a wall-mounted shelf with a towel.
A group of people sitting at picnic tables outdoors, surrounded by trees and a fenced area.
A playground with slides and swings, a mailbox, and a caution sign.
A swimming pool with a green deck and white lounge chairs. There are buildings in the background with a 'No Driving' sign.

17. Current River Inn

Current River Inn
Van Buren
United States
Doreen
£89
includes taxes & fees
13 Oct - 14 Oct
Current River Inn
Property amenity
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

18. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Rubin
£87
includes taxes & fees
18 Oct - 19 Oct
TownePlace Suites by Marriott Sikeston
A living room with a blue wall, a fireplace, a sofa, and a chair.
A bar area with stools and a counter where a bartender is serving drinks.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

19. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
Miranda
£86
includes taxes & fees
13 Oct - 14 Oct
EC Reed's Mercantile and Hotel
A bedroom with a bed, bedside table, and wall-mounted light fixtures.
A dining area with a wooden table, chairs, and a vase with flowers. There is a refrigerator and a microwave in the kitchen area.
A cozy living room with a sofa, armchairs, a coffee table, and a lamp. There are wall art pieces and a mirror.
A wooden cabin with a balcony, a small attached room, and a clear sky in the background.

20. Johnson's Shut-ins State Park

Johnson's Shut-ins State Park
Middle Brook
United States
Aleksandr
Johnson's Shut-ins State Park
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Southeast Missouri.
The Riverview

The Riverview

777 Main St Cape Girardeau MO
£86
14 Oct - 15 Oct
includes taxes & fees
The Riverview
Urban Lofts

Urban Lofts

104 North Jackson Street Perryville MO
Get ratesUrban Lofts
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Room was clean, staff was courteous and helpful. Breakfast was good, nice spread."
Darnetta 1-night trip
Posted 5 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Awesome place will be staying in more of them"
Tim 1-night trip
Posted 9 hours ago
Drury Inn & Suites Sikeston, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent
"Nice clean large room, basic breakfest, plenty of parking"
Sherrie 1-night trip
Posted 15 hours ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Find out more about Southeast Missouri

Frequently asked questions

What are the best 3-star hotels in Southeast Missouri?
If you're staying in Cape Girardeau for your Southeast Missouri holiday, you'll find some cosy 3-star hotels. Many Expedia travellers book Courtyard by Marriott Cape Girardeau Downtown. Around 0.4 mi west of the downtown area, it features a terrace and a cafe. Another highly rated escape is Drury Plaza Hotel Cape Girardeau Conference Centre. Book a room here and enjoy access to a swimming pool and high-speed internet services, and be approximately 5 mi west of the centre.
How much does it cost to stay in a 3-star hotel in Southeast Missouri?
Use Expedia's sort and search filters to land an affordable 3-star hotel for your Southeast Missouri break. Just set your maximum rate with our pricing tool. You can also pick your amenities, preferred neighbourhood and lots more.
  • Search for the lowest price per night right now from £86
What is the difference between a 4-star and 3-star hotel in Southeast Missouri?
Relaxation is effortless in 3-star hotels in Southeast Missouri. In addition to pleasant surroundings, these more affordable stays come with a wealth of amenities like WiFi, coffee maker and on-site gym. A 4-star hotel offers a more sophisticated experience with upscale features such as an on-site spa centre, outdoor or indoor pool and more spacious rooms. Regardless of your desired hotel category or budget, we have the ideal match for you.

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