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Check availability on Southeast Missouri 2 Star Hotels

Tonight
5 Oct - 6 Oct
Tomorrow
6 Oct - 7 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Southeast Missouri 2-star hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Elizabeth
£61
includes taxes & fees
11 Oct - 12 Oct
Pear Tree Inn Cape Girardeau West
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.
A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.

2. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United Kingdom
Mark
£47
includes taxes & fees
1 Nov - 2 Nov
Baymont Inn and Suites by Wyndham Farmington, MO
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.
A hotel room with a living area, kitchenette, and a desk with a computer and chair.
A hotel lobby with a seating area, a reception desk, and a dining area.

3. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
United States
Michelle
£63
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn Festus - St Louis South
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.
Lobby
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

4. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
David
£57
includes taxes & fees
1 Nov - 2 Nov
Days Inn and Suites by Wyndham Sikeston
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.
Pool
Snack bar
Exterior

5. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Rhonda
£77
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Poplar Bluff
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

6. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
£67
includes taxes & fees
6 Oct - 7 Oct
Motel 6 Poplar Bluff, MO
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

7. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
William
£49
includes taxes & fees
14 Oct - 15 Oct
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A hotel lobby with a seating area, a reception desk, and a bar.
A kitchen counter with a coffee machine, a kettle, and storage boxes.
A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

8. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Lisa
£87
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Perryville by IHG
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

9. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
£87
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.
A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.

10. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
United States
Steven
£91
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

11. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Shelley
£72
includes taxes & fees
11 Oct - 12 Oct
Best Western Plus Sikeston I-55
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

12. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
Stephanie
£95
includes taxes & fees
14 Oct - 15 Oct
Crown Pointe Lodge, BW Signature Collection
A hotel room with two beds, a TV, a desk, and a wardrobe.
A reception desk with a sign reading "The FARMSTEAD," a vending machine with snacks, and a water cooler.
A living room with a large flat-screen TV, two beige sofas, a coffee table, and a wooden side table.
A spacious lobby with a reception desk, a chandelier, and a large window.

13. The Farmstead Hotel

The Farmstead Hotel
Caruthersville
United States
Alex
£82
includes taxes & fees
6 Oct - 7 Oct
The Farmstead Hotel
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel room with a bed, a TV, a desk, and a chair.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

14. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
£77
includes taxes & fees
11 Oct - 12 Oct
Candlewood Suites Cape Girardeau by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

15. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
John
£91
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn Sikeston
A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.
A hotel room with a bed, a desk, a chair, a couch, and a TV.
An indoor swimming pool with a 3 FT depth marker, surrounded by white walls and a ceiling with recessed lighting.
A reception area with a green marble counter, framed certificates on the wall, and a clock.

16. Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
Bonne Terre
United States
Elizabeth
£54
includes taxes & fees
11 Oct - 12 Oct
Super 8 by Wyndham Bonne Terre
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
A hotel with a covered entrance, multiple windows, and a yellow facade.
A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.
A hotel room with a bed, a sofa, a small table, and a painting on the wall.

17. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
£63
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn Poplar Bluff North
A modern retail area with a display of local items and snacks.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

18. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
£77
includes taxes & fees
11 Oct - 12 Oct
Tru By Hilton Cape Girardeau
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.
A modern kitchen with granite countertops, wooden chairs, and a dining table. There are various food items and a sign indicating hot beverages.

19. Quality Inn Farmington

Quality Inn Farmington
Farmington
United States
Tracy
£50
includes taxes & fees
25 Oct - 26 Oct
Quality Inn Farmington
A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.
A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.

20. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
United States
Marisa
£51
includes taxes & fees
11 Oct - 12 Oct
Super 8 by Wyndham Farmington
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
£85
11 Oct - 12 Oct
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
£82
11 Oct - 12 Oct
includes taxes & fees
Drury Inn & Suites Sikeston, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD Jackson MO
£66
1 Nov - 2 Nov
includes taxes & fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"The stay here gets better every time."
cynthia 1-night trip
Posted 2 days ago
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"Great place"
BRANDY 1-night trip
Posted 2 days ago
Super 8 by Wyndham Sikeston/Miner Area
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"Terrific base accommodation. Clean, efficient. I use this place whenever I’m in the area. I’m"
Herman 1-night trip
Posted 4 days ago
Motel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"This was a very good value. It has been the best hotel I've stayed at in awhile."
David 1-night trip
Posted 2 weeks ago
Days Inn and Suites by Wyndham Sikeston

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