Search Adults Only Resorts & Hotels in Southeast Missouri

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Adults Only Resorts & Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Southeast Missouri

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,020 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
United States
William
The price is £64
includes taxes & fees
21 Jun - 22 Jun
Drury Inn & Suites Jackson MO

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (78 reviews)
"The Experience was amazing and we enjoyed the views and the firepit!"
United States
Kenzia
The price is £106
includes taxes & fees
23 Jun - 24 Jun
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Deerfield Inn & Suites Steele Near Blytheville I 55

Deerfield Inn & Suites Steele Near Blytheville I 55
2.5 star property
Steele
The price is £42
includes taxes & fees
18 Jun - 19 Jun
Deerfield Inn & Suites Steele Near Blytheville I 55

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (201 reviews)
"The room was clean, the staff was extremely helpful with our check in!"
United States
Travis
The price is £78
includes taxes & fees
5 Jul - 6 Jul
Fairfield Inn & Suites by Marriott Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (135 reviews)
"This is a clean, quiet, well designed hotel."
United States
Kendra
The price is £76
includes taxes & fees
1 Jul - 2 Jul
Tru By Hilton Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,000 reviews)
"Wonderful room and food offerings were extra thoughtful."
United States
Jonna
The price is £84
includes taxes & fees
12 Jul - 13 Jul
Drury Plaza Hotel Cape Girardeau Conference Center

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (99 reviews)
"It was a very neat experience! Highly recommend you stop here and get away from big chain hotels for a night. The staff were super friendly and the restaurant/store was so nostalgic!"
United States
DANIELLE
The price is £76
includes taxes & fees
19 Jun - 20 Jun
EC Reed's Mercantile and Hotel

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (875 reviews)
"Nice quiet overnight stay."
United States
Tammy
The price is £81
includes taxes & fees
13 Jul - 14 Jul
Hampton Inn Poplar Bluff

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (594 reviews)
"Beautiful new hotel didn’t disappoint! Rey comfortable beds. Great breakfast and attentive staff keeping things filed for the best guest experience. I would definitely stop there again on my next trip through Perryville!"
United States
Cheryl
The price is £86
includes taxes & fees
25 Jun - 26 Jun
Holiday Inn Express & Suites Perryville by IHG

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,017 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
United States
Stephanie
The price is £81
includes taxes & fees
28 Jun - 29 Jun
Drury Inn & Suites Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southeast Missouri Hotel Reviews

Frequently asked questions

How can I find cheap adults-only hotels in Southeast Missouri?
Expedia is here to help you locate cheap adults-only hotels in Southeast Missouri. Simply try out our convenient filter tool to select amenities, star rating and budget to refine your search results and lock in the best stay in just a few keystrokes.
From what age can you stay in an adult-only hotel in Southeast Missouri?
Many adult-only resorts and hotels in Southeast Missouri require guests to be 16, 18 or 21 years old. Age restrictions can vary across properties, so always check the rules. Ready for an exciting holiday just for grown-ups? Whether you're two people or 20, celebrating a birthday, honeymoon or wedding, Expedia has the perfect adult-only hotel or resort to suit your needs.
Are all adult-only resorts all-inclusive in Southeast Missouri?
If you're pining for a hassle-free getaway, an adult-only all-inclusive resort serves up some serious R&R. To see what's available in Southeast Missouri, enter your dates of travel and then click on the "all-inclusive" filter. Keep an eye out for stays marked as "adults only." Click on the properties you'd like to view to find out what you can expect for your money. The rate normally covers the room, food and drinks, on-site activities and entertainment.
Why book your adults-only hotel in Southeast Missouri with Expedia?
With affordable prices and an excellent selection of properties in Southeast Missouri, Expedia is your one-stop travel site for an adults-only escape. Stick to the budget and opt for a cosy motel, or spoil your darling to a romantic couples retreat in a luxury hotel.
When is the best time to stay at an adult-only all-inclusive resort in Southeast Missouri?
The best time to stay at an adult-only all-inclusive resort or hotel in Southeast Missouri depends on a few factors, starting with the weather. Also consider whether you prefer to experience the energy of peak season, when demand for flights and hotels is high, or the low season, when things are a bit less hectic. Weigh up your style and travel budget before locking in your dream adult-only getaway that offers the whole nine yards!
Can I cancel or change my adult-only resort booking?
You can cancel or change your booking, but check the fine print in your itinerary or make your way to Expedia's Trips portal to figure out what rules apply. Whether you'll be charged a fee depends on the type of adult-only hotel or resort booking you made. Haven't locked in your Southeast Missouri break yet? Search for adult-only hotels that allow a full refund — for when life gets in the way!

Explore a world of travel with Expedia