Title: Panama Spa Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Spa-Hotels.0-0-d2897-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on Panama Spa Hotels Tonight [2 Feb - 3 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-02&endDate=2026-02-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Feb - 4 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-03&endDate=2026-02-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-06&endDate=2026-02-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-13&endDate=2026-02-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama hotels with a spa ![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/9e776b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Bella Vista 8.8/10 Excellent (1,003 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hugh £128 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) Tocumen 8.6/10 Excellent (2,409 reviews) "Very nice hotel and good restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allen £93 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Couples treatment room(s), steam room, Turkish bath/hammam](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (660 reviews) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £200 includes taxes & fees 28 Feb - 1 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Panama City 9.0/10 Wonderful (1,008 reviews) "friendly staff, clean amenities, convenient location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dumity £129 includes taxes & fees 20 Feb - 21 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/620cc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) Bella Vista 9.4/10 Exceptional (1,003 reviews) "All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PROBIR MAYUR £156 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Urban Suite,1 King, Partial City view | In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,006 reviews) "Second time staying and it was flawless." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony £160 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Couples treatment room(s), Turkish bath/hammam, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) Barrio Sur 8.2/10 Very good (857 reviews) "Nice clean room and the staff was so friendly. Mr Javier was such a great guy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bernard £81 includes taxes & fees 21 Feb - 22 Feb [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8d3d5a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/c28c4592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) Casco Viejo 9.8/10 Exceptional (585 reviews) "Beautiful place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £263 includes taxes & fees 24 Feb - 25 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (1,008 reviews) "Super friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Geoffrey £108 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Bella Vista 8.8/10 Excellent (1,002 reviews) "Huge hotel wit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katya £173 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=142&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "excellent room and location" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Always great value for the price!" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Nice stuff. Very welcoming and cheerful people. Clean. Closhopping centers " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The first room was clean but the window has moisture in between the panel so you can’t see outside. The next day I told the front desk and they rectified it by moving us to a different room with no hustle " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "The room was very comfortable, air-condition worked great. " [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The location was terrific making it easy to catch an Uber to pretty much anywhere you wanted to go. Pool & fitness area were as expected & the room was comfortable. We were here for 4 nights. Loved that it was attached to the mall." [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Room was clean and check in was quick. Literally right next to the airport so it is perfect for a layover " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Room was great, excellent view, clean and spacious." [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "They stay were extremely courteous to us. A little delayed check in but we were able to store our luggage and use their facilities. El Panama is one of my favorite places to stay… so many memories here. " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information)