Title: Panama Spa Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing a beach, landscape views and tropical scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25691-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Spa Hotels in Panama ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Spa-Hotels.0-0-d2897-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on Panama Spa Hotels Tonight [19 Sept - 20 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-19&endDate=2025-09-20&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-20&endDate=2025-09-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-19&endDate=2025-09-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Spa Hotels ![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/827121a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View | City view](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/cc5e4adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, City View | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/b2066790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott Bella Vista 8.8/10 Excellent (988) "2nd stay at Sortis Hotel in Panama. Never disappoints. Breakfast Buffett incredible and staff pleasant and attentive! Will stay there again!" £122 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/da7a9306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG Tocumen 8.4/10 Very good (2232) "Great hotel near the airport " £99 includes taxes & fees 27 Sept - 28 Sept [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Couples treatment room(s), steam room, Turkish bath/hammam](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ff18df89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (608) "Staff was lovely - especially front desk, door staff, cleaning team and room service. Only critique is that service was very slow in the restaurant both times but otherwise a lovely visit. " £169 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/38485558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/e3f1253f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel Panama City 9.0/10 Wonderful (1004) "Had an amazing stay with my family " £103 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/b594ef85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1008) "We had an amazing time, great hotel and great breakfast. " £149 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/7a936012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Supreme Suite, 1 King, Partial City view, Corner room | In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/d1c75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/557ce8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama Bella Vista 9.0/10 Wonderful (1005) "Great hotel " £156 includes taxes & fees 3 Oct - 4 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Couples treatment room(s), Turkish bath/hammam, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, Superior Room, Breakfast Included | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/c5fb33f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6 AM to 8 PM, pool loungers](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/b883cd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino Barrio Sur 8.2/10 Very good (784) "Always a great choice for stay!" £71 includes taxes & fees 4 Oct - 5 Oct [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/743a753a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/be6fe9a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/03089f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/f19135cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City Casco Viejo 9.8/10 Exceptional (509) "Great stay" £237 includes taxes & fees 1 Oct - 2 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/57cdf539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/19f9d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/25adc131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama San Francisco 8.6/10 Excellent (950) "Great staff and beautiful hotel. Will definitely stay again!" £109 includes taxes & fees 26 Sept - 27 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/8590a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/ae99e466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama Bella Vista 8.8/10 Excellent (1003) "Great property You don’t go wrong Amenities are great Location is perfect area safe and walkable rooms are nice large clean modern " £179 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05®ionId=142&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Decapolis Hotel Panama City](//images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Nice staff...recognoze my loyalty to hotel. I was upgraded to a suite." [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Really nice hotel With very good breakfast options " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Novotel Panama City](//images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Staff was great!" [](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Marriott Panama Hotel](//images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Great staff. Great morning buffet and friendly overall people. " [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities " [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "I had to spend the night in Panama to continue my trip to South America. Is very convenient I think is the closest hotel to the airport, the shuttle service is a plus. The rides go every hour sharp. Staff is great, food is amazing as well panameño chicken soup was delicious after a long trip I recover all the energy. They are very close to the freeway so I don’t think there are any walking distance shopping around but you can go anywhere with a taxi, is safe and rides are not expensive. " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "I arrived with low expectations after reading several reviews, but I was pleasantly surprised by my experience at this resort. The customer service truly stood out. Carlo, the bell attendant, provided excellent assistance, and Edwin, the bartender, delivered consistently outstanding service. He crafted my Old Fashioned perfectly every time, demonstrating both skill and pride in his work. The dining options were very good overall. The seafood and Italian restaurants were both excellent and highly recommended. The poolside restaurant offered attentive service, though the food quality did not match the other venues. Additionally, despite netting around the restaurant, birds often made their way inside, which was distracting and unappealing. The accommodations are comfortable but dated. The furniture showed noticeable wear and stains, and the mini refrigerator was in need of replacement. A deeper cleaning would also enhance the overall guest experience. Despite these issues, I was still able to enjoy my room. Guests should also be aware that the resort is located approximately one hour from the airport. In summary, while there are areas that could be improved, I had an enjoyable stay and would gladly return in the future." [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "This was an awesome trip! The hotel was well worth the $$. The people were nice and the area was great! I will be back!!!" [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "The staff were great! Very prompt! Any needs they were right there to attend! " [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information)