Title: Panama Spa Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing a beach, landscape views and tropical scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25691-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Spa Hotels in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Spa-Hotels.0-0-d2897-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on Panama Spa Hotels Tonight [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-04&endDate=2025-11-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [5 Nov - 6 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-05&endDate=2025-11-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Spa Hotels ![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/827121a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View | City view](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/cc5e4adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, City View | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/b2066790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/7fb69592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott Bella Vista 8.8/10 Excellent (1006) "The staff is amazing especially the bellman Samuel, very helpful very knowledgeable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynderia £133 includes taxes & fees 22 Nov - 23 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/da7a9306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG Tocumen 8.4/10 Very good (2294) "Great location near airport updated hotel " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joe £102 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Couples treatment room(s), steam room, Turkish bath/hammam](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ff18df89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (622) "great service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gianluca £171 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/e3f1253f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/38485558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel Panama City 9.0/10 Wonderful (1011) "The staff is hospitable and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) BIBI FARANAZ £112 includes taxes & fees 7 Nov - 8 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Classic, 1 King Bed, Non-Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1020) "Highly recommended for business trips. Very good breakfast with quality food. Nice boutique hotel vibe in the city." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Lu-Ting £157 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/7a936012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/557ce8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Supreme Suite, 1 King, Partial City view, Corner room | In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/d1c75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama Bella Vista 9.0/10 Wonderful (1002) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasmine A £150 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Couples treatment room(s), Turkish bath/hammam, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6 AM to 8 PM, pool loungers](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/b883cd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, Superior Room, Breakfast Included | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/c5fb33f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino Barrio Sur 8.2/10 Very good (800) "Everything was great good service and everything clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zulema £73 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/353bb85d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/fae422a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/edb97b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite 1 King Oceant Front | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/4debbd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City Casco Viejo 9.8/10 Exceptional (524) "My favorite hotel in Panama love the view and the colonial interior decoration" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Franck £260 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/57cdf539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/19f9d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/1f8c9ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama San Francisco 8.6/10 Excellent (972) "Centrally located and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio £112 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/8590a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama Bella Vista 8.8/10 Excellent (1005) "Great property You don’t go wrong Amenities are great Location is perfect area safe and walkable rooms are nice large clean modern " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suzanne £176 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=142&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Novotel Panama City](//images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "We had a great stay and excellent service. Staff was friendly all round, room was clean and fresh, breakfast was really good. highly recommended. Thank you, hope to see you soon. " [](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Everything went smoothly. Room was more than i expected" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Great choices of Latin and European food options." [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Room was excellent" [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![W Panama](//images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "Yes " [](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Hotel architecture location and friendliness’s of staff" [](https://expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Studio Coliving](//images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/e86f18bd_y.jpg) ### Studio Coliving 10/10 Excellent "Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here" [](https://expedia.co.uk/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Yea bar was well stocked " [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Sheraton Grand Panama](//images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Clean room and helpful staff. " [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)