Title: Panama Spa Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Spa-Hotels.0-0-d2897-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on Panama Spa Hotels Tonight [19 Mar - 20 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-03-19&endDate=2026-03-20&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Mar - 21 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-03-20&endDate=2026-03-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-03-20&endDate=2026-03-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-03-27&endDate=2026-03-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama hotels with a spa ![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/9e776b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Bella Vista 8.8/10 Excellent (1,002 reviews) - Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey. £132 includes taxes & fees 28 Mar - 29 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) Tocumen 8.6/10 Excellent (2,492 reviews) £112 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Couples treatment room(s), steam room, Turkish bath/hammam](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (677 reviews) - Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape. £149 includes taxes & fees 10 Apr - 11 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Panama City 9.0/10 Wonderful (1,000 reviews) £134 includes taxes & fees 10 Apr - 11 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) Bella Vista 9.4/10 Exceptional (1,000 reviews) - Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat. £159 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/8f2104c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Urban Suite,1 King, Partial City view | In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,005 reviews) - Revitalise at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting. £212 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Couples treatment room(s), Turkish bath/hammam, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/53f67005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) Barrio Sur 8.2/10 Very good (878 reviews) - Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape. £89 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8d3d5a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/9fe67709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) Casco Viejo 9.8/10 Exceptional (617 reviews) - Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel. £396 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (1,006 reviews) - Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await. £111 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Bella Vista 8.8/10 Excellent (1,000 reviews) - Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate. £162 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-03&endDate=2026-04-04®ionId=142&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Spa-Hotels.0-0-d142-tSpaHotels.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 8/10 Good "The hotel is simple but nice. We stayed in the junior suite which was spacious and clean. The staff was cordial. We would definitely stay there again. " [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Lovely food at their restaurant, clean rooms and perfect location close to airport" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg) ### Ramada Plaza by Wyndham Panama Punta Pacifica 10/10 Excellent "Everything about Ramada was excellent only thing was you could of heard when a toilet flush from neighbors or neighours talking on the outside but other than that it was perfect would definitely stay here again and would also recommend to others. " [](https://expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 2/10 Terrible "Mold in the bathroom " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 6/10 Okay "The room was fine, cleaning staff great. The front desk is a gong show. No one seemed to know what was going on, the staff were not helpful. The pool only had 4 lounge chairs, the cushions were very dirty. The pool was not clean and the pool decking was very dirty. Nothing had been scrubbed up there for some time." [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Fantastic pool. Great food, I'd recommend the fish and chips. Best I've ever had. Great bar. Friendly staff. " [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 2/10 Terrible "I NEVER COULD ENTER! You charged me twice the price plus the hotel charged me again and I never used the room due to the fact that the system in the hotel was broken when we tried to check in. YOU MUST REIMBURSE ME and the hotel too!" [](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "For an older hotel, they keep it up. " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 6/10 Okay "Not what the pictures show. Found a roach in my room. Bathroom dirty. Elevator dirty. Definitely does not match the reviews. Pool area is beautiful. " [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)