Title: Holiday Rentals Panama from £81: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Tourist arriving beautiful beach with crystal clear turquoise water.](https://images.trvl-media.com/place/142/8856f331-62a4-460d-af0a-8c4dbaebf5cc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) ## Our top choices for Panama holiday rentals ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Premium bedding, in-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f6eaf73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (162) "Everything was great, helpful staff, great room , clean, excellent service!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory Walter £91 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/edba2188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/568d88f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | View from room](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/5cdc54c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (218) "The view was amazing and the place was great could stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yonnette [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Standard Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/0a056e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/b2adfd51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/20a4e482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/f71ce331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) Bella Vista 8.8/10 Excellent (483) "The buffet bar and great customer service. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayhiuska [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen | Fridge, microwave, oven, electric kettle](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.2/10 Wonderful (54) "Great stay, would recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/faee5c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/f0ebed1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Clementinas [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) Casco Viejo 9.4/10 Exceptional (171) "The front desk receptionist was extremely helpful! The room was clean and comfortable! We would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) april £127 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Superior Double Room | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c337dae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/5b01afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (King) | Private kitchen | Full-sized fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6bdd4504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Isabela Suites [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) Casco Viejo 10/10 Exceptional (171) "Wonderful charming property in the heart of the historic district. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/f7211254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Apartment | Balcony view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2d6249fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Apartment | Beach/ocean view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/a7c64715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.2/10 Very good (49) "Nice view & very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Latricia £132 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment (3G) | Balcony](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/b4a2ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Dining room](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/e16a4424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/dc7a8e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/f5328136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cuadra by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) El Chorrillo 9.2/10 Wonderful (44) "Love the property. You are right at the start of the nice part of casco viejo but the blocks around it are rough and ugly. The police are very prominent so it's safe but be on alert" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos £110 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/b51e58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/a3d62646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/48e220ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/7a081d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.4/10 Good (155) "Clean room good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gideon [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Honeymoon Studio, Hot Tub, Valley View | Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/f1920aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Studio Suite, 1 Queen Bed, Kitchenette, Garden Area | In-room dining](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/w4030h2268x0y0-0bf2c10e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/c5c10649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Studio, Hot Tub, Valley View | Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/b46898c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Alejandro [](https://www.expedia.co.uk/Boquete-Hotels-Villa-Alejandro.h46550459.Hotel-Information) Boquete 8.8/10 Excellent (130) "Priced right, easy walk to town, safe, quiet & overall great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.co.uk/Boquete-Hotels-Villa-Alejandro.h46550459.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09H) | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/e1902a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11B) | Balcony](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/w2996h2000x4y0-ef85e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (10D) | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/96b85842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) San Francisco 9.2/10 Wonderful (56) "Clean and walkable location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamera £138 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) ![Design Suite, 1 King Bed, Mountain View | Premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/903374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite | Private kitchenette | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/29a7e7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/19d8b56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f86e54de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro [](https://www.expedia.co.uk/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) Boquete 9.4/10 Exceptional (91) "Nice stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos [](https://www.expedia.co.uk/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/576f28cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/8679b43b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/26ebabc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![SUITE ALBANY | Pillow-top beds, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/e250353b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ESHEL SUITES PANAMA [](https://www.expedia.co.uk/Panama-City-Hotels-ESHEL-SUITES-PANAMA.h100639469.Hotel-Information) San Francisco 10/10 Exceptional (5) "Loved the property and the location, it was clean , nice and I really enjoyed my stay there" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aron [](https://www.expedia.co.uk/Panama-City-Hotels-ESHEL-SUITES-PANAMA.h100639469.Hotel-Information) ![Luxury Apartment | View from room](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/cdf7fcb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/179c218f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/e6079dcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/d206b5b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surfside Beachfront Suites by Playa Caracol Resorts [](https://www.expedia.co.uk/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) Punta Chame 7.4/10 Good (28) "Great, clean condo overlooking the pool and ocean. We didn't cook our meals, but used the restaurant on site. Staff was friendly and professional. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Timothy £201 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/155ac5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (8B) | Private kitchen | Fridge, microwave, oven, toaster](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b8e57e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4f5c676f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.8/10 Good (27) "I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shamia [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Outdoor pool, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/b3283f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | 65-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a2b1fb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/00770912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panama & Arts Tower [](https://www.expedia.co.uk/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) Bella Vista 9.4/10 Exceptional (49) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANGEL [](https://www.expedia.co.uk/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) ![Club Cabin | Living area](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/ceaebfc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cookware/dishes/utensils, kitchen islands](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/ecd071fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/8ba1e0a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/af8b7fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabañas Naturaleza [](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Cabanas-Naturaleza.h89420538.Hotel-Information) Bocas del Toro 9.4/10 Exceptional (12) "Awesome place" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Renata [](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Cabanas-Naturaleza.h89420538.Hotel-Information) ![Apartment (CM3) | Living room | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/70782ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (CM5) | Living room | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/67865bff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM2) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/8b966ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM4) | Balcony view](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/e80a24a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Mallet by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) Casco Viejo 9.8/10 Exceptional (25) " It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Navyatha [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Apartment (CC4B) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1A) | Premium bedding, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d5409722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/f49b7db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Dining room](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d8108baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) Casco Viejo 8.2/10 Very good (20) "Great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jad £126 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Deluxe Apartment | Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Dining room](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97ac72d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/af0ed434.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) Casco Viejo 7.4/10 Good (40) "The nightlife around there was incredible" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix £81 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Holiday-Rental-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Holiday-Rental-Destinations) ## Top Panama Hotel Reviews ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "S" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/11d7a719_y.jpg) ### JW Marriott Panama 10/10 Excellent "Just wonderful hotel" [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Yes to both" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "What an amazing experience! From the staff to the overall hospitality! Surprised my mom with this trip for her bday and it surpassed my expectations. I will def be returning! " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "Excellent good service good people good everything love it" [](https://expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "It was a very nice stay. The room is nice, organized and clean with a great view of the city. The blankets are a little too warm and we wished for a lighter blankets. Breakfast buffet was very good with many food choices and best custom eggs cooked tailored to our demands. Uber to Casco Viejo was cheap. Uber to PTY airport was $17\. Views from the hotel are beautiful. Pool was the best, clean, lots of lights, cozy and just what we needed to swim after long day of sightseing Panama canal, boat tour to Monkey Islands, long walk along Cinta Costera and dinner with friends on the 5th floor of Golden tower." [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Everything! View breakfast friendliness" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Muito bom" [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "First time stay was nice . " [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ## Find out more about Panama **Everything you need to know about** **Panama** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panama holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. **Panama holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Panama holiday rentals we have selected for you start as low as £81 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Panama rentals** At Expedia, we put the best Panama holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Popular Panama Cities - All accommodation types in Panama - [Panama City Holiday Rentals ](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) - [Bocas del Toro Holiday Rentals ](https://expedia.co.uk/Bocas-Del-Toro-Holiday-Rentals.d6023445.Travel-Guide-HolidayRentals) - [David Holiday Rentals ](https://expedia.co.uk/David-Holiday-Rentals.d500195.Travel-Guide-HolidayRentals) - [Playa Coronado Holiday Rentals ](https://expedia.co.uk/Playa-Coronado-Holiday-Rentals.d6053187.Travel-Guide-HolidayRentals) - [Las Tablas Holiday Rentals ](https://expedia.co.uk/Las-Tablas-Holiday-Rentals.d6347532.Travel-Guide-HolidayRentals) - [Alto Boquete Holiday Rentals ](https://expedia.co.uk/Alto-Boquete-Holiday-Rentals.d6245664.Travel-Guide-HolidayRentals) - [Apartments in Panama ](https://expedia.co.uk/Panama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) - [Holiday Homes in Panama ](https://expedia.co.uk/Panama-Private-Holiday-Homes.d142-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Condo Rentals in Panama ](https://expedia.co.uk/Panama-Condos.d142-aaCondos.Travel-Guide-Accommodation) - [B&B in Panama ](https://expedia.co.uk/Panama-Bed-And-Breakfasts.d142-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Villas in Panama ](https://expedia.co.uk/Panama-Villas.d142-aaVillas.Travel-Guide-Accommodation) - [Cabin Rentals in Panama ](https://expedia.co.uk/Panama-Cabins.d142-aaCabins.Travel-Guide-Accommodation) - [Hostels in Panama ](https://expedia.co.uk/Panama-Hostels.d142-aaHostels.Travel-Guide-Accommodation) - [Serviced Apartments in Panama ](https://expedia.co.uk/Panama-Apart-Hotels.d142-aaApartHotels.Travel-Guide-Accommodation) - [Lodges in Panama ](https://expedia.co.uk/Panama-Lodges.d142-aaLodges.Travel-Guide-Accommodation) - [Guest Houses in Panama ](https://expedia.co.uk/Panama-Guest-Houses.d142-aaGuestHouses.Travel-Guide-Accommodation) - [Houseboats in Panama ](https://expedia.co.uk/Panama-Houseboats.d142-aaHouseboats.Travel-Guide-Accommodation) - [Resorts in Panama ](https://expedia.co.uk/Panama-Hotel-Resorts.d142-aaHotelResorts.Travel-Guide-Accommodation) - [Cottages in Panama ](https://expedia.co.uk/Panama-Cottages.d142-aaCottages.Travel-Guide-Accommodation) - [Chalets in Panama ](https://expedia.co.uk/Panama-Chalets.d142-aaChalets.Travel-Guide-Accommodation) - [Farmstay in Panama ](https://expedia.co.uk/Panama-Agritourism.d142-aaAgritourism.Travel-Guide-Accommodation) - [Inns in Panama ](https://expedia.co.uk/Panama-Inns.d142-aaInns.Travel-Guide-Accommodation) - [Caravan Parks in Panama ](https://expedia.co.uk/Panama-Caravan-Parks.d142-aaCaravanParks.Travel-Guide-Accommodation) - [Condo Resorts in Panama ](https://expedia.co.uk/Panama-Condominium-Resorts.d142-aaCondominiumResorts.Travel-Guide-Accommodation) - [Treehouses in Panama ](https://expedia.co.uk/Panama-Treehouses.d142-aaTreehouses.Travel-Guide-Accommodation) - 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