Title: Holiday Rentals Panama from £51: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25685-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in Panama ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) ## Top Holiday Rentals in Panama ## Our top choices for Panama holiday rentals ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/4e9d4ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | 1 bedroom, premium bedding, in-room safe, cots/infant beds](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f6eaf73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites Costa del Este 9.2/10 Wonderful (74) "Comfortable & good location" £79 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/edba2188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/568d88f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | View from room](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/5cdc54c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama Bella Vista 7.8/10 Good (158) "Excellent location and the views were amazing" [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Standard Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/0a056e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/b2adfd51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/29d0d0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/f71ce331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites Bella Vista 8.8/10 Excellent (468) "Everything was just perfect will be back soon. " [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/96b85842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11B) | Balcony](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/w2996h2000x4y0-ef85e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09H) | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/e1902a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco by Wynwood House San Francisco 9.4/10 Exceptional (49) "Good comfy rooms" £96 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/b51e58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/48e220ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/a3d62646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/7a081d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar San Francisco 7.6/10 Good (131) "Great view with access to the pool and gym." £123 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen | Fridge, microwave, oven, electric kettle](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Duplex | Living area | Smart TV](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/32dc2d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments Santa Ana 9.4/10 Exceptional (47) "Great stay, would recommend." [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/faee5c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Clementinas Casco Viejo 9.4/10 Exceptional (162) "Great Food , excellent bar.... soft beds and pillows.... five stars will come again !" £95 includes taxes & fees 29 Sept - 30 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/077501d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Apartment | Balcony view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2d6249fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments Bella Vista 7.8/10 Good (34) "Will stay there again " £61 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment (3G) | Balcony](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/b4a2ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/f5328136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/8ac950b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Dining room](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/e16a4424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cuadra by Wynwood House El Chorrillo 9.4/10 Exceptional (38) "Nice place!" £73 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Superior Double Room | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c337dae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/cb84ac89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (King) | Private kitchen | Full-sized fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6bdd4504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/5b01afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Isabela Suites Casco Viejo 10/10 Exceptional (158) "Love this place! Especially for two couples orba family. " [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Apartment (CC4B) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Dining room](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d8108baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/f49b7db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1A) | 2 bedrooms, premium bedding, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d5409722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House Casco Viejo 8.6/10 Excellent (19) "Great place!" £76 includes taxes & fees 22 Sept - 23 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Apartment, 2 Bedrooms (2C) | 1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3a166248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (4B) | Dining room](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/e8a22a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1A) | Private kitchen | Fridge, microwave, oven, toaster](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/56b38ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1B) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/5945d7c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House Casco Viejo 8.4/10 Very good (40) "I always love to stay at Wynwood properties in Panama " £53 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Deluxe Apartment | 1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Private kitchen | Fridge, microwave, toaster, blender](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/7d5fb04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/af0ed434.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Dining room](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97ac72d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House Casco Viejo 7.4/10 Good (34) "Great for dining and night clubs" £53 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/b50fc181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2C) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/f0719162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/8f7fd7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House Casco Viejo 8.4/10 Very good (16) "Great location. At the border of renovated areas but an extremely go deal for this great property. " £80 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Apartment, 2 Bedrooms (CM2) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM4) | Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/9659c91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM1) | Dining room](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/242a1c2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (CM5) | Living area | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/3681eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Mallet by Wynwood House Casco Viejo 9.8/10 Exceptional (23) " It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. " £111 includes taxes & fees 23 Sept - 24 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/576f28cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/cc7cdfb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![SUITE KINGSTON | Living area](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/913700d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![SUITE ALBANY | 1 bedroom, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/e250353b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ESHEL SUITES PANAMA San Francisco 10/10 Exceptional (5) "Loved the property and the location, it was clean , nice and I really enjoyed my stay there" [](https://www.expedia.co.uk/Panama-City-Hotels-ESHEL-SUITES-PANAMA.h100639469.Hotel-Information) ![Outdoor pool, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | 65-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a2b1fb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/b3283f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/00770912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panama & Arts Tower Bella Vista 9.4/10 Exceptional (37) "The room size and views were fantastic. Fully functional kitchen and dinning area. A "home away from home." " [](https://www.expedia.co.uk/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) ![Honeymoon Studio, Hot Tub, Valley View | 2 bedrooms, Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/f1920aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Studio, Hot Tub, Valley View | 2 bedrooms, Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/b46898c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Studio Suite, 1 Queen Bed, Kitchenette, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/7a6a1a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Studio Suite, 1 Queen Bed, Kitchenette, Garden Area | In-room dining](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/w4030h2268x0y0-0bf2c10e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Alejandro Boquete 8.8/10 Excellent (118) "Priced right, easy walk to town, safe, quiet & overall great stay! " [](https://www.expedia.co.uk/Boquete-Hotels-Villa-Alejandro.h46550459.Hotel-Information) ![Design Suite, 1 King Bed, Mountain View | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/903374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f86e54de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite | Private kitchenette | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/29a7e7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Garden View | Living area | 43-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/a6c217b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro Boquete 9.6/10 Exceptional (76) "Nice stay!" [](https://www.expedia.co.uk/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Apartment (20) | 1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/d5acebbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/bc995ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09) | Private kitchen | Fridge, microwave, stovetop, toaster](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/f1ebeb16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House Santa Ana 7.0/10 Good (14) "Great hotel. Very close to Casco viejo" £51 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04®ionId=142&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Holiday-Rental-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Holiday-Rental-Destinations) ## Top Panama Hotel Reviews ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Next to airport and shuttle runs hourly" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "Waymore hotel is excellent " [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Great location" [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![The Executive Hotel](//images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Staff was great! I really enjoyed my stay this time. They have stepped up their game. Breakfast was good " [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Decapolis Hotel Panama City](//images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Good " [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Wonderful stay. The staff was first class and made me feel at home as a solo traveler. I got a great deal on my reservation, staying during the work week, and the value was fantastic. A great all inclusive experience. Gracias!" [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Plaza Paitilla Inn Hotel](//images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Love it" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Studio Coliving](//images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/e86f18bd_y.jpg) ### Studio Coliving 10/10 Excellent "Overall a nice place." [](https://expedia.co.uk/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) ![AC Hotel by Marriott Panama City](//images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/d365d94c_y.jpg) ### AC Hotel by Marriott Panama City 10/10 Excellent "AC Hotel is always a great stay for the money" [](https://expedia.co.uk/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information) ## Find out more about Panama **Everything you need to know about** **Panama** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panama holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search.  **Panama holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama holiday rentals we have selected for you start as low as £51 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Panama rentals** At Expedia, we put the best Panama holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Popular Panama Cities - All accommodation types in Panama - [Panama City Holiday Rentals](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) - [Bocas del Toro Holiday Rentals](https://expedia.co.uk/Bocas-Del-Toro-Holiday-Rentals.d6023445.Travel-Guide-HolidayRentals) - [David Holiday Rentals](https://expedia.co.uk/David-Holiday-Rentals.d500195.Travel-Guide-HolidayRentals) - [Playa Coronado Holiday Rentals](https://expedia.co.uk/Playa-Coronado-Holiday-Rentals.d6053187.Travel-Guide-HolidayRentals) - [Alto Boquete Holiday Rentals](https://expedia.co.uk/Alto-Boquete-Holiday-Rentals.d6245664.Travel-Guide-HolidayRentals) - [Las Tablas Holiday Rentals](https://expedia.co.uk/Las-Tablas-Holiday-Rentals.d6347532.Travel-Guide-HolidayRentals) - [Apartments in Panama](https://expedia.co.uk/Panama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) - [Holiday Homes in Panama](https://expedia.co.uk/Panama-Private-Holiday-Homes.d142-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Condo Rentals in Panama](https://expedia.co.uk/Panama-Condos.d142-aaCondos.Travel-Guide-Accommodation) - [B&B in Panama](https://expedia.co.uk/Panama-Bed-And-Breakfasts.d142-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Villas in Panama](https://expedia.co.uk/Panama-Villas.d142-aaVillas.Travel-Guide-Accommodation) - [Cabin Rentals in Panama](https://expedia.co.uk/Panama-Cabins.d142-aaCabins.Travel-Guide-Accommodation) - [Hostels in Panama](https://expedia.co.uk/Panama-Hostels.d142-aaHostels.Travel-Guide-Accommodation) - [Serviced Apartments in Panama](https://expedia.co.uk/Panama-Apart-Hotels.d142-aaApartHotels.Travel-Guide-Accommodation) - [Lodges in Panama](https://expedia.co.uk/Panama-Lodges.d142-aaLodges.Travel-Guide-Accommodation) - [Guest Houses in Panama](https://expedia.co.uk/Panama-Guest-Houses.d142-aaGuestHouses.Travel-Guide-Accommodation) - [Houseboats in Panama](https://expedia.co.uk/Panama-Houseboats.d142-aaHouseboats.Travel-Guide-Accommodation) - [Resorts in Panama](https://expedia.co.uk/Panama-Hotel-Resorts.d142-aaHotelResorts.Travel-Guide-Accommodation) - [Cottages in Panama](https://expedia.co.uk/Panama-Cottages.d142-aaCottages.Travel-Guide-Accommodation) - [Chalets in Panama](https://expedia.co.uk/Panama-Chalets.d142-aaChalets.Travel-Guide-Accommodation) - [Farmstay in Panama](https://expedia.co.uk/Panama-Agritourism.d142-aaAgritourism.Travel-Guide-Accommodation) - [Inns in Panama](https://expedia.co.uk/Panama-Inns.d142-aaInns.Travel-Guide-Accommodation) - [Caravan Parks in Panama](https://expedia.co.uk/Panama-Caravan-Parks.d142-aaCaravanParks.Travel-Guide-Accommodation) - [Castles in Panama](https://expedia.co.uk/Panama-Castles.d142-aaCastles.Travel-Guide-Accommodation) - [Condo Resorts in Panama](https://expedia.co.uk/Panama-Condominium-Resorts.d142-aaCondominiumResorts.Travel-Guide-Accommodation) - [Capsule Hotels in Panama](https://expedia.co.uk/Panama-Capsule-Hotels.d142-aaCapsuleHotels.Travel-Guide-Accommodation) ### Expedia's Latest Trends Hotels - 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