Panama City Holidays from £1,095

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £335 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your Panama City Holiday

The tropical climate, cosmopolitan vibe and rich history are three of the many reasons why people love this coastal city. Discover this incredible destination as you please with a Panama City holiday package. Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama are just a few of the sights worth exploring during your trip to Panama City. A few quick clicks is all it takes to put together your dream Panama City holiday on Expedia.

Top Panama City Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hyatt Regency Panama City

The Annual Holiday Sale

Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save.

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Things to do in and around Panama City

Panama City is an excellent destination for family, business, or city-themed vacations, offering a variety of activities. Visitors can enjoy vibrant shopping centres and malls, while also exploring exciting Panama tours, jungle trails, and top sights. For the adventurous, a volcano hike provides an exhilarating experience amidst the stunning landscapes of the region.

Shopping

In Panama City, you can enjoy shopping at Albrook Shopping Mall and Pacific Center, both offering a variety of stores and entertainment. For a unique experience, visit Uruguay Street, known for its local businesses. If you're up for a drive, explore more shopping centres outside the city for additional options.

Recreation

At Estadio Rommel Fernandez, immerse yourself in the vibrant sports atmosphere while enjoying various physical activities. The National Theater offers a cultural retreat, perfect for experiencing captivating performances in a romantic setting. For sports enthusiasts, Estadio Nacional Rod Carew provides an energetic environment to engage in recreational events.

Adventure

Embark on the Honeycreeper Ridge Trail, a stunning hike 40.2km from Panama City, where scenic views and adventure await. For a thrilling experience, try Gatun Eco Adventures' zipline ropes course, located 46.7km away, offering exhilarating outdoor fun amidst lush surroundings.

Nightlife

Panama City's nightlife is vibrant and diverse, with venues like the stylish Tantalo Rooftop for stunning views and cocktails. For a lively dance scene, check out Casa Jaguar, while the upscale Barlovento offers a relaxed atmosphere to enjoy local brews and tapas. Exciting nights await.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Panama City

Panama City offers a delightful mix of family-friendly, urban, and business-themed activities, making it an ideal vacation spot. Explore vibrant streets, attend events at conference venues, or unwind in urban parks. The city's attractions provide a rich cultural experience for all travellers. Don't miss the iconic Panama Canal, a must-see highlight that will enhance your visit to this dynamic city.

  • Cinta Costera: This scenic urban park offers a delightful blend of family-friendly activities, outdoor spaces, and vibrant city vibes. Stroll along its picturesque pathways, enjoy stunning views of the Pacific Ocean, and take in the lively atmosphere as locals and tourists alike gather to relax, exercise, and socialise.
  • Metropolitan Cathedral of Panama: A stunning example of colonial architecture, this cathedral showcases Panama's rich cultural heritage. Its intricate design and historical significance make it a must-see for culture enthusiasts, while the serene atmosphere invites quiet reflection and appreciation of its artistic beauty.
  • Panama Canal Railway: This historic rail journey offers a unique insight into Panama's engineering marvel, connecting the Atlantic and Pacific Oceans. Experience breathtaking views of lush landscapes and the canal itself, while learning about its pivotal role in global trade and history.

Best time to go to Panama City

The best time to visit Panama City is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnySlightly HighSlightly High
February79.2°F (26.2°C)No RainMostly SunnyAverageAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowAverage

Tips to save on your trip to Panama City

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Panama City.
  • Consider traveling to Panama City during the low season (September to November) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Panama City Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Max Temp Winter
29ºC
Max Temp Summer
29ºC
Top Sights
Metropolitan Cathedral of Panama, Soberania National Park and Frank Gehry Biodiversity Museum

Top hotels in Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £112 per night from 8 Mar to 9 Mar
£112
8 Mar - 9 Mar
includes taxes & fees
9/10 Wonderful! (5,021 reviews)
Had a great stay-great room and food! Unfortunately gift shop was closed for the duration of my stay

Reviewed on 27 Feb 2026

Hotel Riu Plaza Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £88 per night from 23 Mar to 24 Mar
£88
23 Mar - 24 Mar
includes taxes & fees
7.8/10 Good! (1,002 reviews)
Yes greet staff jefeth in front desk, good food, good pool

Reviewed on 25 Feb 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £109 per night from 8 Mar to 9 Mar
£109
8 Mar - 9 Mar
includes taxes & fees
8.6/10 Excellent! (1,001 reviews)
The staff was courteous and overall very helpful. The spaces were clean. They had easy access to taxis if you needed them and the breakfast buffet, and restaurants were delicious. We did ask for extra water a few times and it was stated it would be brought up and never was. Other than that, the stay ...

Reviewed on 23 Feb 2026

Sheraton Grand Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

What to do in Panama City

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.