A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Our top choices for Panama City adults-only hotels

1. Tantalo Hotel

Tantalo Hotel
3.5 star property
Casco Viejo
8.8 out of 10, Excellent, (340 reviews)
"Staff was amazing! Rooms are large with all the amenities you would need! Beautiful art and aesthetic to every room!"
United States
Cynthia
The price is £63
includes taxes & fees
17 Nov - 18 Nov
Tantalo Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panama City

Discover top Panama City attractions

Panama City offers a captivating blend of culture, history, and adventure that will delight any traveller. Start your journey in the vibrant Casco Viejo district, where you can explore charming colonial architecture, savor local cuisine at artisanal eateries, and enjoy breathtaking views of the skyline from the waterfront. For those interested in history, the Panama Canal's visitor area provides a fascinating look at this engineering marvel, complete with informative exhibits and the opportunity to witness ships passing through the locks. Nature lovers will appreciate the nearby Metropolitan Natural Park, a sprawling green oasis perfect for birdwatching and leisurely hikes, all while being just a stone's throw from the urban hustle. Don't miss the Amador Causeway, where you can rent bikes and pedal along the scenic waterfront, taking in stunning views of the city and the Pacific Ocean. Finally, indulge in a shopping spree at local artisan markets where you can find unique crafts and souvenirs, ensuring your trip is filled with memorable treasures. With a variety of luxurious accommodations in these vibrant neighborhoods, you're sure to find a comfortable base from which to explore this dynamic city.

Find the best adults only resorts & hotels in Panama City

For those seeking a tranquil escape in Panama City, these top hotels cater exclusively to adult guests, ensuring a serene and sophisticated atmosphere.

Tantalo Hotel

  • Why it's great for an adults only getaway: The Tantalo Hotel stands out as a premier destination for adult travellers, an excellent review rating of 8.8. This adults-only hotel in the charming Casco Viejo neighbourhood offers a chic atmosphere with a rooftop terrace where guests can unwind and enjoy stunning views of the historic district. The hotel's exclusive guest policy ensures a peaceful retreat for all visitors seeking relaxation and sophistication.
  • Other amenities: Guests will appreciate various conveniences including 24-hour airport shuttle service and valet parking for easy arrivals and departures. The hotel features daily housekeeping, air conditioning for comfort, and a concierge service that can assist with local attractions. With its Art Deco design and premium bedding, Tantalo Hotel promises a stylish and comfortable stay, complemented by onsite shopping options and free bicycles for exploring the vibrant surroundings.
  • Neighborhood: Casco Viejo
  • Nearby attractions: Avenida Balboa - 0.7 km, Metropolitan Cathedral of Panama - 0.4 km, National Theater - 1 km

Top Panama City Hotel Reviews

Frequently asked questions

How much do adults-only hotels in Panama City cost?
The price for adults-only hotels in Panama City may vary due to, among other things, the star rating and amenities included with your stay. Whatever your budget, you'll discover a grown-up getaway where you'll be able to unwind in peace and quiet with Expedia.

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