Title: Holiday Rentals Panama City from £59: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Panama City Travel Guide](https://expedia.co.uk/Panama-City.dx2897)[Hotels in Panama City](https://expedia.co.uk/Panama-City-Hotels.d2897.Travel-Guide-Hotels)[Flights to Panama City](https://expedia.co.uk/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.co.uk/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Panama City Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-City.d2897.Car-Hire-Guide)[Panama City Holidays](https://expedia.co.uk/Panama-City.d2897.Holidays-City-Breaks) ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [24 Apr - 26 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama City holiday rentals ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/c0384242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1b369fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) 8.8/10 Excellent (509 reviews) "Excellent place, friendly staff, great breakfast and many shops close by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond £75 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (King) | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6f5654fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (Queen) | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/f680e3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Casco Viejo [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) 10/10 Exceptional (179 reviews) "Excellent place to stay in the Casco Viejo " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zoe M [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/7c635746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![15 outdoor pools](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/bee413e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) £58 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Costa del Este [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) 9.4/10 Exceptional (220 reviews) "Really loved this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandra £102 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/9f6bde45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/cf36effb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/b407ee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/046bf4b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco [](https://www.expedia.co.uk/Panama-City-Hotels-Comfortable-2BR-City-Apartment.h123391242.Hotel-Information) £132 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Comfortable-2BR-City-Apartment.h123391242.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/b4d43ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/3d688297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/w3995h2667x0y0-2d9fa044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/0835e528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information) 8.8/10 Excellent (691 reviews) "Enjoyed the stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breneda £110 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information) ![Apartment (14D) | Dining room](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/2a0412bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (14D) | Soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/422dd5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11F) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/3115996f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (5E) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/e5dc9f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) £126 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/765b1a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Casco Viejo [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) 9.4/10 Exceptional (181 reviews) "Fabulous room and wonderful people that work there. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leah £130 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/9f96d68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Amador [](https://www.expedia.co.uk/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) 8.4/10 Very good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto £71 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/03e26607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in Santa Ana [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) 9.0/10 Wonderful (74 reviews) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris £59 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) 8.0/10 Very good (30 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/46eb55a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/3b43323d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/9c70698c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/267d4c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco [](https://www.expedia.co.uk/Panama-City-Hotels-Wanders-Panama-By-Boutique-Apartments.h114580453.Hotel-Information) 10/10 Exceptional (3 reviews) "The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £254 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Wanders-Panama-By-Boutique-Apartments.h114580453.Hotel-Information) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/c0e07415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/375f6530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/4d9b3d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/601ad506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Veracruz [](https://www.expedia.co.uk/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) £112 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) ![Apartment (11G) | Living room | Heated floors](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/dcaddcd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (24D) | Laundry](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/6d2627e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (13J) | Living area | Heated floors](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/w1788h1200x0y0-a490f57d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (17C) | Balcony](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/48b1ae26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-The-Gray-By-Wynwood-House.h111348561.Hotel-Information) [](https://www.expedia.co.uk/Panama-City-Hotels-The-Gray-By-Wynwood-House.h111348561.Hotel-Information) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391241/cdb96e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391241/fea7599f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391241/68f0c531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391241/1e48baf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco [](https://www.expedia.co.uk/Panama-City-Hotels-Urban-2BR-Apt-In-Central-Area.h123391241.Hotel-Information) £141 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Urban-2BR-Apt-In-Central-Area.h123391241.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen | Coffee/tea maker](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/04577a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Casco Viejo [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) 8.8/10 Excellent (22 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette £90 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment (3G) | Living area | 40-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/01dcce3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Private kitchen | Fridge, microwave, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/17bc3100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3K) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/035f9f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/9f5c2914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in El Chorrillo [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) 9.0/10 Wonderful (49 reviews) "Superb customer service. Instant responsiveness. Almost miraculous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter £100 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/7cba0a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/737ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) 7.6/10 Good (256 reviews) "Great location and good amenities for 1st time travellers Pool view is amazing... " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) nikita [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/9e5233d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/9e64cab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms | Street view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/cc8558b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) 7.4/10 Good (170 reviews) "Clean room good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gideon £161 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) 8.2/10 Very good (63 reviews) "Great location, wonderful views, spacious apartment, with comfortable bed and good ac. Amenities in the building are great too." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alan £151 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11®ionId=2897&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=VR_SPRING_PROMO_2897) ## Find holiday rentals that suit your style Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=APARTMENT) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=APART_HOTEL) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=CONDO) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=VACATION_HOME) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=VILLA) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=CABIN) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=HOUSE_BOAT) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-05-25&d1=2026-05-25&endDate=2026-05-28&d2=2026-05-28&lodging=COTTAGE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) ## Top Panama City Hotel Reviews ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "Yes " [](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Everything was perfect" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Aloft Panama](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0_y.jpg) ### Aloft Panama 10/10 Excellent "Amazing like always" [](https://expedia.co.uk/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "The hotel was wonderful. The entire hotel was clean, staff welcoming especially security employee Flash. The breakfast buffet was great and it was so nice that Divney the receptionist remembered our names each day. My overall stay was great and I would highly recommend this hotel to anyone visiting Panama. " [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Really nice and great breakfast" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Staff was great and friendly. Room was clean and loved the view. Was surprised there were no washcloths but that’s probably a cultural thing. I know to bring my own for next time. " [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "No problems at check in, clean room. Plan on utilizing again when we come back " [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "The room was exceptional and tge staff were kind and friendly. I will definitely stay there again." [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Yes nice and clean" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ## Find out more about Panama City **Everything you need to know about** **Panama City** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panama City holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama City holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Panama City holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Panama City. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama City holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Panama City holiday rentals we have selected for you start as low as £59 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Panama City rentals** At Expedia, we put the best Panama City holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Panama City rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama City holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama City. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in Panama City ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) - [Hostels in Panama City ](https://expedia.co.uk/Panama-City-Hostels.d2897-aaHostels.Travel-Guide-Accommodation) - [Serviced Apartments in Panama City ](https://expedia.co.uk/Panama-City-Apart-Hotels.d2897-aaApartHotels.Travel-Guide-Accommodation) - [Lodges in Panama City ](https://expedia.co.uk/Panama-City-Lodges.d2897-aaLodges.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find holiday rentals in Panama City? ### What are some of the best holiday rentals that Panama City has to offer? ### How many holiday rentals are there in Panama City? ### What can I see and do in Panama City? ### What are holiday rentals like in Panama City? ### Expedia's Latest Trends Hotels - [El Cangrejo Hotels](https://expedia.co.uk/El-Cangrejo-Panama-City-Hotels.0-n6285972-0.Travel-Guide-Filter-Hotels) - [Hotels in Miramar](https://expedia.co.uk/Miramar-Hotels.d553248623282266307.Travel-Guide-Hotels) - [Hotels in Bocas del Toro](https://expedia.co.uk/Bocas-Del-Toro-Hotels.d6023445.Travel-Guide-Hotels) - [Casco Viejo Hotels](https://expedia.co.uk/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall](https://expedia.co.uk/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Hotels in Bocas del Toro](https://expedia.co.uk/Bocas-Del-Toro-Hotels-All-Inclusive-Hotel.0-0-d6023445-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Villas Palma de Mallorca](https://expedia.co.uk/Palma-De-Mallorca-Villas.d2829-aaVillas.Travel-Guide-Accommodation) - [Hotels in Nata](https://expedia.co.uk/Nata-Hotels.d553248623451085027.Travel-Guide-Hotels) - [Obarrio Hotels](https://expedia.co.uk/Obarrio-Panama-City-Hotels.0-n3000663487-0.Travel-Guide-Filter-Hotels) - [Hotels in Atalaya](https://expedia.co.uk/Atalaya-Hotels.d3000007476.Travel-Guide-Hotels) Flights - [Cheap Flights from London (LHR) to Boston (BOS)](https://expedia.co.uk/lp/flights/lhr/bos/london-to-boston) - [Cheap Flights to Pedasí](https://expedia.co.uk/Cheap-Flights-To-Pedasi.d6130073.Travel-Guide-Flights) - [Cheap Flights to David](https://expedia.co.uk/Cheap-Flights-To-David.d500195.Travel-Guide-Flights) - [Cheap Flights to Colon](https://expedia.co.uk/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights) - [Cheap Flights to Bocas del Toro](https://expedia.co.uk/Cheap-Flights-To-Bocas-Del-Toro.d6023445.Travel-Guide-Flights) Activities - [Things to do in Colon](https://expedia.co.uk/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities) - [Things to do in Bocas del Toro](https://expedia.co.uk/Things-To-Do-In-Bocas-Del-Toro.d6023445.Travel-Guide-Activities) - [Things to do in Tocumen](https://expedia.co.uk/Things-To-Do-In-Tocumen.d6053184.Travel-Guide-Activities) Packages - [Bocas del Toro Holidays](https://expedia.co.uk/Bocas-Del-Toro.d6023445.Holidays-City-Breaks) - [Albrook Shopping Mall](https://expedia.co.uk/Albrook-Shopping-Mall-Panama-City.d6159851.Attraction) - [China Holidays](https://expedia.co.uk/China.d37.Holidays-City-Breaks) - [Boquete Holidays](https://expedia.co.uk/Boquete.d500194.Holidays-City-Breaks) - [Taboga Holidays](https://expedia.co.uk/Taboga.d6268388.Holidays-City-Breaks) - [David Holidays](https://expedia.co.uk/David.d500195.Holidays-City-Breaks) General - [Visit Boquete](https://expedia.co.uk/Boquete.dx500194) - [Visit El Cangrejo](https://expedia.co.uk/Panama-City-El-Cangrejo.dx6285972) - [Visit Campo Alegre](https://expedia.co.uk/Panama-City-Campo-Alegre.dx553248635976397615) - [Visit Costa del Este](https://expedia.co.uk/Panama-City-Costa-Del-Este.dx3000663480) - [Visit Obarrio](https://expedia.co.uk/Panama-City-Obarrio.dx3000663487) - [Visit Calidonia](https://expedia.co.uk/Panama-City-Calidonia.dx3000663488) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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