Title: The 10 Best 5 Star Hotels in Panama City - 2025 Updated Prices | Expedia.co.uk [Panama City Travel Guide](https://expedia.co.uk/Panama-City.dx2897)[Hotels in Panama City](https://expedia.co.uk/Panama-City-Hotels.d2897.Travel-Guide-Hotels)[Holiday Rentals in Panama City](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals)[Flights to Panama City](https://expedia.co.uk/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.co.uk/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Panama City Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-City.d2897.Car-Hire-Guide)[Panama City Holidays](https://expedia.co.uk/Panama-City.d2897.Holidays-City-Breaks) ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Panama City, Panamá Province - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama City 5 Star Hotels Tonight [27 Nov - 28 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2025-11-27&endDate=2025-11-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Nov - 29 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2025-11-28&endDate=2025-11-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2025-11-28&endDate=2025-11-30&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=2897&startDate=2025-12-05&endDate=2025-12-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama City 5 Star Hotels ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/ec5ee8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/bc4b23d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama Bella Vista 9.0/10 Wonderful (4592) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) yohosy £95 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; French cuisine ](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/246e2668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/a7b599bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/361a474e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama Bella Vista 9.0/10 Wonderful (1004) "Very beautiful room was spotless, and staff was very good with customer service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony £143 includes taxes & fees 6 Dec - 7 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/557ce8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse I, Suite, 1 King, Partial City view | Living room | LCD TV, iPod dock](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/c594bc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Supreme Suite, 1 King, Partial City view, Corner room | In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/d1c75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama Bella Vista 9.0/10 Wonderful (1005) "Clean room, great views, great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £153 includes taxes & fees 6 Dec - 7 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/11d7a719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/22b0bcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama San Francisco 9.0/10 Wonderful (1009) "Spotless, friendly and great food. Great pools a restaurants. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David £176 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/fae422a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite 1 King Oceant Front | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/4debbd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ba99cac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/edb97b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City Casco Viejo 9.8/10 Exceptional (542) "Great hotel and location " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Russell £320 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/ae99e466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/8590a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama Bella Vista 8.8/10 Excellent (1003) "Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Salvador £155 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![3 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/d8a24106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/731f1fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e679a1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama Veracruz 8.0/10 Very good (1006) "Staff very friendly, clean room, amazing food&drinks" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley Ethel £138 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![40-inch Smart TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d8dfdd09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/136ac6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9cd155ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9320a181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Panama City Hotel Bella Vista 8.8/10 Excellent (92) "Great location and amazing staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aziz £91 includes taxes & fees 6 Dec - 7 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Classic, 1 King Bed, Non-Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/b594ef85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1007) "great stay when in PTY" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernando £150 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c77947e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (633) "Beautiful property. Excellent lunch, fish tacos were amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc £187 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/22e383ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/90613175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/b225554a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá San Francisco 8.4/10 Very good (1001) "Great stay! Very safe!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARVIN [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/9750e503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/67ba0beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/e6ea2c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/9a094222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waymore Hotel Spa and Casino Bella Vista 6.2/10 (1001) "It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldo [](https://www.expedia.co.uk/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Panama-City-Hotels.s50-0-d2897.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Panama-City-Hotels.s50-0-d2897.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City. ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Crowne Plaza Panama Airport by IHG Ave. Domingo Diaz Tocumen Panama £98 23 Dec - 24 Dec includes taxes & fees 8.4/10 Very Good! (2,298 reviews) [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Megapolis Hotel Panamá Avenida Balboa Panama City £107 19 Dec - 20 Dec includes taxes & fees 8.4/10 Very Good! (1,224 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Las Americas Golden Tower Panama Av. Balboa con Calle 53 Panama City Panama £95 14 Dec - 15 Dec includes taxes & fees 8.8/10 Excellent! (1,023 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) Still don't see what you're looking for? [See all properties in Panama City.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F11%2F2025&endDate=29%2F11%2F2025®ionId=2897&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F11%2F2025&endDate=29%2F11%2F2025®ionId=2897&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F11%2F2025&endDate=29%2F11%2F2025®ionId=2897&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F11%2F2025&endDate=29%2F11%2F2025®ionId=2897&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F11%2F2025&endDate=29%2F11%2F2025®ionId=2897&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F11%2F2025&endDate=29%2F11%2F2025®ionId=2897&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Panama City The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch. [See all hotels in Panama City](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-11&endDate=2025-12-12&adults=2®ionId=2897) ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=900&h=336&p=1&q=high) ## Top Panama City Hotel Reviews ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The room was very clean, we found the staff very polite and accommodating. The breakfast buffet was excellent. Great selection of drinks, also. Great experience in general! " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Fabulous stay!" [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Great service and attention" [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "The staff was exceptional, the suite I got was everything plus more of what I expected! 10/10, highly recommend! Loved the panoramic views!" [](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ## Find out more about Panama City ## Frequently asked questions ### What are the best 5-star hotels in Panama City? > According to Expedia guest reviews, [Bristol Panama, a Registry Collection Hotel](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information), [W Panama](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) and [Waldorf Astoria Panama](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) are among the top 5-star hotels in Panama City. Providing top-quality amenities and unmatchable service, you'll enjoy a luxurious and memorable stay. ### How much does it cost to stay in a 5-star hotel in Panama City? > How much you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a luxurious getaway. > > > > - Search for the lowest price per night from £95 ### What makes a hotel 5 stars in Panama City? > From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Panama City is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer remarkable guest-centric services like in-room beauty treatments, on-site laundry and dry cleaning and room service any time day or night. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - [Hotels near Albrook Shopping Mall](https://www.expedia.co.uk/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Hotels near Ancon Hill](https://www.expedia.co.uk/Ancon-Hill-Hotels.0-l6286129-0.Travel-Guide-Filter-Hotels) - [Barrio Chino Hotels](https://www.expedia.co.uk/Barrio-Chino-Panama-City-Hotels.0-n714749931894550528-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Bella Vista](https://www.expedia.co.uk/Bella-Vista-Panama-City-Hotels-Gay-Friendly-Hotel.0-n3000663485-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Service in Bella Vista](https://www.expedia.co.uk/Bella-Vista-Panama-City-Hotels-Hotel-With-Laundry-Service.0-n3000663485-0-thotelwithlaundryservice.Travel-Guide-Filter-Hotels) - [Bella Vista Hotels](https://www.expedia.co.uk/Bella-Vista-Panama-City-Hotels.0-n3000663485-0.Travel-Guide-Filter-Hotels) - [Calidonia Hotels](https://www.expedia.co.uk/Calidonia-Panama-City-Hotels.0-n3000663488-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Campo Alegre](https://www.expedia.co.uk/Campo-Alegre-Panama-City-Hotels-Gay-Friendly-Hotel.0-n553248635976397615-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Campo Alegre Hotels](https://www.expedia.co.uk/Campo-Alegre-Panama-City-Hotels.0-n553248635976397615-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Boutique-Hotel.0-n6285189-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Hilton-Hotels.0-n6285189-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Historic-Hotel.0-n6285189-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Wedding-Hotel.0-n6285189-0-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Casco Viejo Hotels](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Cinta Costera](https://www.expedia.co.uk/Cinta-Costera-Hotels.0-l6245970-0.Travel-Guide-Filter-Hotels) - [Curundu Hotels](https://www.expedia.co.uk/Curundu-Panama-City-Hotels.0-n553248623199107736-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Hotels in Panamá Province](https://www.expedia.co.uk/Destinations-In-Panama-Province-All-Inclusive-Hotel.0-0-d6246281-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Gay-Friendly Hotels in Panamá Province](https://www.expedia.co.uk/Destinations-In-Panama-Province-Gay-Friendly-Hotel.0-0-d6246281-tGayFriendlyHotel.Hotel-Filter-Destinations) - [Panamá Province Hotels](https://www.expedia.co.uk/Destinations-In-Panama-Province.d6246281.Hotel-Destinations) - [El Cangrejo Hotels](https://www.expedia.co.uk/El-Cangrejo-Panama-City-Hotels.0-n6285972-0.Travel-Guide-Filter-Hotels) - [Hotels near Estación Lotería](https://www.expedia.co.uk/Estacion-Loteria-Hotels.d553248635125946139.Travel-Guide-Hotels) - [Marbella Hotels](https://www.expedia.co.uk/Marbella-Panama-City-Hotels.0-n3000663483-0.Travel-Guide-Filter-Hotels) - [Hotels near Marcos A. Gelabert Intl.](https://www.expedia.co.uk/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels) - [Hotels near Multicentro Panama](https://www.expedia.co.uk/Multicentro-Panama-Hotels.0-l6158230-0.Travel-Guide-Filter-Hotels) - [Obarrio Hotels](https://www.expedia.co.uk/Obarrio-Panama-City-Hotels.0-n3000663487-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Punta Pacifica](https://www.expedia.co.uk/Punta-Pacifica-Panama-City-Hotels-Gay-Friendly-Hotel.0-n3000663482-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Punta Pacifica Hotels](https://www.expedia.co.uk/Punta-Pacifica-Panama-City-Hotels.0-n3000663482-0.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Punta Paitilla](https://www.expedia.co.uk/Punta-Paitilla-Panama-City-Hotels-Pet-Friendly-Hotel.0-n6285983-0-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Punta Paitilla Hotels](https://www.expedia.co.uk/Punta-Paitilla-Panama-City-Hotels.0-n6285983-0.Travel-Guide-Filter-Hotels) - [San Felipe Hotels](https://www.expedia.co.uk/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels) - [San Francisco Hotels](https://www.expedia.co.uk/San-Francisco-Panama-City-Hotels.0-n553248623199112076-0.Travel-Guide-Filter-Hotels) - [Santa Ana Hotels](https://www.expedia.co.uk/Santa-Ana-Panama-City-Hotels.0-n553248623199107606-0.Travel-Guide-Filter-Hotels) - [Hotels near Vía Argentina](https://www.expedia.co.uk/Via-Argentina-Hotels.d553248635998074175.Travel-Guide-Hotels) - [Flights to Marcos A. Gelabert Intl.](https://www.expedia.co.uk/Cheap-Flights-To-Marcos-A-Gelabert-Intl.d4407632.Travel-Guide-Flights) - [Flights from Marcos A. Gelabert Intl.](https://www.expedia.co.uk/lp/airports/pac/flights-from-marcos-a-gelabert-intl-airport) - [Hahn Air Technologies Bocas del Toro (BOC) to Panama City (PAC) flights](https://www.expedia.co.uk/lp/flight-routes/hahn-air-technologies-from-bocas-del-toro-intl-to-marcos-a-gelabert-intl/x1/boc/pac) - [Flights from Bilbao (BIO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bio/pac/bilbao-to-panama-city) - [Flights from Bocas del Toro (BOC) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/boc/pac/bocas-del-toro-to-panama-city) - [Flights from Baltimore (BWI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bwi/pac/baltimore-to-panama-city) - [Flights from Belize City (BZE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bze/pac/belize-city-to-panama-city) - [Flights from Columbia (CAE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cae/pac/columbia-to-panama-city) - [Flights from Waco Kungo (CEO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ceo/pac/waco-kungo-to-panama-city) - [Flights from Changuinola (CHX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/chx/pac/changuinola-to-panama-city) - [Flights from Chi Mei (CMJ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cmj/pac/chi-mei-to-panama-city) - [Flights from Cartagena (CTG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ctg/pac/cartagena-to-panama-city) - [Flights from David (DAV) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dav/pac/david-to-panama-city) - [Flights from Delhi (DEL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/del/pac/delhi-to-panama-city) - [Flights from Durban (DUR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dur/pac/durban-to-panama-city) - [Flights from Dubai (DXB) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dxb/pac/dubai-to-panama-city) - [Flights from La Fortuna (FON) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fon/pac/la-fortuna-to-panama-city) - [Flights from Frankfurt (FRA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fra/pac/frankfurt-to-panama-city) - [Flights from Ghimbi (GHD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ghd/pac/ghimbi-to-panama-city) - [Flights from Glasgow (GLA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gla/pac/glasgow-to-panama-city) - [Flights from Guatemala City (GUA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gua/pac/guatemala-city-to-panama-city) - [Flights from Guayaquil (GYE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gye/pac/guayaquil-to-panama-city) - [Flights from Hong Kong (HKG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/hkg/pac/hong-kong-to-panama-city) - [Flights from Istanbul (IST) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ist/pac/istanbul-to-panama-city) - [Flights from Jabalpur (JLR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/jlr/pac/jabalpur-to-panama-city) - [Flights from La Paz (LAP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lap/pac/la-paz-to-panama-city) - [Flights from Las Vegas (LAS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/las/pac/las-vegas-to-panama-city) - [Flights from Los Angeles (LAX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lax/pac/los-angeles-to-panama-city) - [Flights from London (LHR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lhr/pac/london-to-panama-city) - [Flights from Liberia (LIR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lir/pac/liberia-to-panama-city) - [Flights from London (LON) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lon/pac/london-to-panama-city) - [Flights from Medellín (MDE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mde/pac/medellin-to-panama-city) - [Flights from Mamfe (MMF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mmf/pac/mamfe-to-panama-city) - [Flights from Nice (NCE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/nce/pac/nice-to-panama-city) - [Flights from Newcastle (NCL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ncl/pac/newcastle-to-panama-city) - [Flights from Panama City (PTY) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pty/pac/panama-city-to-panama-city) - [Flights from San Salvador (SAL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sal/pac/san-salvador-to-panama-city) - [Flights from Santo Domingo (SDQ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sdq/pac/santo-domingo-to-panama-city) - [Flights from San José (SJO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sjo/pac/san-jose-to-panama-city) - [Flights from San Juan (SJU) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sju/pac/san-juan-to-panama-city) - [Flights from Springfield (SPI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/spi/pac/springfield-to-panama-city) - [Flights from Syracuse (SYR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/syr/pac/syracuse-to-panama-city) - [Flights from Trinidad (TAD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tad/pac/trinidad-to-panama-city) - [Flights from Tapachula (TAP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tap/pac/tapachula-to-panama-city) - [Flights from Tampa (TPA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tpa/pac/tampa-to-panama-city) - [Flights from Tulcan (TUA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tua/pac/tulcan-to-panama-city) - [Flights from Uberlandia (UDI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/udi/pac/uberlandia-to-panama-city) - [Flights from Owen Sound (YOS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/yos/pac/owen-sound-to-panama-city) - [Flights from Zürich (ZRH) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/zrh/pac/zurich-to-panama-city) - [Albrook Shopping Mall](https://www.expedia.co.uk/Albrook-Shopping-Mall-Panama-City.d6159851.Attraction) - [Calidonia Holidays](https://www.expedia.co.uk/Calidonia.d3000663488.Holidays-City-Breaks) - [Cinta Costera](https://www.expedia.co.uk/Cinta-Costera-Calidonia.d6245970.Attraction) - [Metropolitan Cathedral of Panama](https://www.expedia.co.uk/Metropolitan-Cathedral-Of-Panama-Casco-Viejo.d6078477.Attraction) - [Metropolitan Nature Park](https://www.expedia.co.uk/Metropolitan-Nature-Park-Panama-City.d6078485.Attraction) - [Pacific Center](https://www.expedia.co.uk/Pacific-Center-San-Francisco.d633625826652135424.Attraction) - [Palacio Bolivar](https://www.expedia.co.uk/Palacio-Bolivar-Casco-Viejo.d553248621562725897.Attraction) - [Visit Bella Vista](https://www.expedia.co.uk/Panama-City-Bella-Vista.dx3000663485) - [Visit Bethania](https://www.expedia.co.uk/Panama-City-Bethania.dx553248623199112069) - [Visit Calidonia](https://www.expedia.co.uk/Panama-City-Calidonia.dx3000663488) - [Visit Campo Alegre](https://www.expedia.co.uk/Panama-City-Campo-Alegre.dx553248635976397615) - [Visit Curundu](https://www.expedia.co.uk/Panama-City-Curundu.dx553248623199107736) - [Visit El Cangrejo](https://www.expedia.co.uk/Panama-City-El-Cangrejo.dx6285972) - [Visit Marbella](https://www.expedia.co.uk/Panama-City-Marbella.dx3000663483) - [Visit Obarrio](https://www.expedia.co.uk/Panama-City-Obarrio.dx3000663487) - [Visit Punta Pacifica](https://www.expedia.co.uk/Panama-City-Punta-Pacifica.dx3000663482) - [Visit Punta Paitilla](https://www.expedia.co.uk/Panama-City-Punta-Paitilla.dx6285983) - [Visit Santa Ana](https://www.expedia.co.uk/Panama-City-Santa-Ana.dx553248623199107606)