Beginning of main content

5 Star Hotels in Panama City, Panama

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Panama City Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Panama City 5 Star Hotels

See all 154 Hotels in Panama City
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

Km 6 Road to Veracruz, Panama City
5.0 out of 5.0
4.2 out of 5 (128 reviews)
Wonderful Ocean ViewsA society wedding during our stay was like a free fashion show!
  8 Jul 2017

£126

£126
Trump Ocean Club International Hotel and Tower Panama

Trump Ocean Club International Hotel and Tower Panama

Calle Punta Colon, Punta Pacifica, Panama City
5.0 out of 5.0
4.3 out of 5 (386 reviews)
Pretty good hotel in Panama CityI always stay at the Trump when visiting Panama City on business. The Hotel location is great with easy access to main roads and some pretty good malls. Room size is very good and they are nice if you have to stay in to do a little work. Design is modern and different from your typical hotel. Staff ...
  19 Jul 2017

£116

£116
Bristol Panama

Bristol Panama

Avenida Aquilino de La Guardia, Panama City
5.0 out of 5.0
4.5 out of 5 (153 reviews)
Great hotel and staff..Great hotel and staff. Walking distance to everything we needed. I would definitely stay again.
  14 Jul 2017

£97

£97
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street, Panama City
5.0 out of 5.0
4.5 out of 5 (150 reviews)
Excellent location, awesome staff, great bed!A true surprise and one most worthy of the Waldorf Astoria brand name.
  9 Jul 2017

£119

£119
Map

Pocket Guide: 5 Star Hotels in Panama City

Search for hotels in Panama City on Expedia.co.uk. You can easily find your hotels in Panama City using one of the methods below:

  • View our selection of featured hotels in Panama City
  • Use the map to find hotels in the Panama City neighborhood you prefer
  • Use the filters to see hotels in a specific area of Panama City, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Panama City
  • Enter your travel dates to view the best deals on hotels in Panama City - while they last

Recently booked Panama City hotels

Trump Ocean Club International Hotel and Tower Panama
5.0 out of 5.0
Last booking: 27 minutes ago