Los Santos Holidays

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Your Los Santos Holiday

Unlock the door to adventure with a holiday package to Los Santos. Get your journey underway in Guarare, where its festivals will be among the things that make this city stand out. Why not plan your trip to Los Santos around its most well-known cities? Las Escobas del Venado, Pedasi and Las Tablas are all fantastic places to start. Expedia has everything you need when it comes to planning your Los Santos holiday. From hotels and flights, to activities and more, we're here to help you create a travel experience like no other.

Top destinations in Los Santos

A wide sandy beach with gentle waves, a cloudy sky, and sparse vegetation along the shore.

Pedasí

Pedasí
Colorful thatched-roof huts, a swimming pool, and a tropical landscape.

Punta Mala

Punta Mala

Top Los Santos Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá

Hotel Casa Panamá

Casco Viejo
£470
per person
11 Nov - 14 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
7.6/10 Good! (746 reviews)
Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance.

Reviewed on 16 Sept 2026

Sheraton Grand Panama

Sheraton Grand Panama

San Francisco
£604
per person
11 Nov - 14 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
8.6/10 Excellent! (1,000 reviews)
Hotel Dann Carlton Panamá

Hotel Dann Carlton Panamá

Bella Vista
£511
per person
11 Nov - 14 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9/10 Wonderful! (459 reviews)
Ubicación muy buena, olores a antiguo

Reviewed on 15 Sept 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
£1,352
per person
2 Dec - 11 Dec
found 11 hours ago
Return direct flight included
Edinburgh (EDI) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
£1,334
per person
2 Dec - 11 Dec
found 11 hours ago
Return direct flight included
Edinburgh (EDI) to Panama City (PTY)
8.4/10 Very good! (1,693 reviews)

Los Santos Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Top Sights
Venao Beach, El Uverito Beach and Playa Las Comadres

Top hotels in Los Santos

Villa Marina Hotel

Villa Marina Hotel

Playa Venao Las Escobas del Venado Los Santos
Fully refundableReserve now, pay when you stay
£121
17 Sept - 18 Sept
includes taxes & fees
9.2/10 Wonderful! (177 reviews)
"Revisión de la lámpara de la recámara principal (hace corto circuito). Reparación de elementos flojos en los baños. Suministro adicional de toallas en los baños."

Reviewed on 13 Sept 2026

Villa Marina Hotel
Selina Playa Venao - Hostel

Selina Playa Venao - Hostel

Playa Venao 1 Las Escobas del Venado Los Santos
Fully refundableReserve now, pay when you stay
£55
17 Sept - 18 Sept
includes taxes & fees
7.8/10 Good! (109 reviews)
"Buen hotel , con buen ambiente."

Reviewed on 28 Aug 2026

Selina Playa Venao - Hostel
Playa Venao Hotel Resort

Playa Venao Hotel Resort

Playa Venao Las Escobas del Venado Los Santos
Fully refundableReserve now, pay when you stay
£122
17 Sept - 18 Sept
includes taxes & fees
9/10 Wonderful! (148 reviews)
"Other than we happened to be there when the septic system needed to be drained... it was a wonderful place to be."

Reviewed on 23 Aug 2026

Playa Venao Hotel Resort
See all 379 properties in Los Santos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Why should I book my Los Santos holiday with Expedia?
Expedia has you covered for all aspects of your next Los Santos holiday. You'll always get the best prices around, but when you bundle your airfares, accommodation and/or hire car into a holiday package, you'll score even bigger savings. Looking to really make the most of your stay? Add some activities and tours to your package. We offer flexible cancellation policies on almost all bookings, so there's no need to stress if your plans change. Head over to our Customer Service Portal link to find out more.
When is the best time of year to holiday in Los Santos?
Los Santos can get busy in January, March and May, so if you want to steer clear of the crowds, visit in June, July and December. To get an idea of the type of weather you can experience, the average daytime temperature in January, the coolest month in Los Santos, is 25ºC. The warmest month here is February, when temperatures average 26ºC.
What are the top hotels for my holiday in Los Santos?
Hotel El Sitio Playa Venao and Hostal Pachamama know how to make their guests feel at home in Las Escobas del Venado. If your itinerary also includes Pedasi, take a look at Hotel Punta Franca and Hotel El Sitio Playa Venao. Both are popular with travellers.
How do I get a cheap holiday to Los Santos?
Find flights that fit your schedule, add a hotel to your booking and watch the savings pile up with a Los Santos holiday. It's that simple! From flights and hotels to activities and hire cars, Expedia is where your cheap getaway begins. And with more than 400 partner airlines and 321,000 properties across the globe to choose from, you'll never be short of choice. Learn more about how you can save money on your next holiday when you book a flight and hotel together with Expedia.
What should I do on my Los Santos holiday?
You'll find plenty of things to put on your itinerary during your holiday in Los Santos. Venao Beach, El Uverito Beach, Playa El Toro and Los Destiladeros Beach are among the leading attractions.
Do I need a visa for my Los Santos holiday?
Official government websites have all the information you need on visa requirements, application procedures and any necessary documentation. Your nationality and the purpose of your visit, whether it be for work or pleasure, will determine if you need a visa for Los Santos. Also be sure that your passport is up to date and has at least six months validity remaining after your planned date of return. Finalise all your travel planning well ahead of time to avoid any last-minute surprises.
What should I wear on my Los Santos holiday?
Think about the types of things you'll be doing during your Los Santos holiday and travel with pieces that you can easily mix and match. For fashion inspiration or even information on dress codes, look up style blogs or social media accounts. It's also wise to monitor the forecast so you can pack appropriately. February is the warmest month in Los Santos, with average temperatures of 26ºC. January is when much of this destination is at its coolest, so get packing to suit daily temperatures of around 25ºC.
What does an Expedia Los Santos holiday include?
Flights, hotels and a cool set of wheels for all your fun road trip adventures. Simply mix and match your favourite bundle and gain access to great discounts. Once you've made your booking, add on a couple of tours and experiences and watch your savings pile up. When it comes to planning your Los Santos break, you're the one in control! Expedia offers a wide range of properties in Los Santos, giving you the flexibility to tailor your escape. Private holiday homes and villas are two of the most in-demand stays for our guests here.
Does Expedia offer Book Now, Pay Later Los Santos holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book an incredible getaway without eating away at your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your escape. Check out these flexible payment options:
  • Pay monthly holidays: Klarna offers easy monthly payment plans that suit all types of budgets, so you can have that well-deserved holiday sooner.
  • No-deposit holidays: Clicking on the "book now" button is much easier with this payment plan. With no deposit required for your escape, you can Book Now, Pay Later and start working on your travel itinerary.
Can I choose my airline with a Los Santos Expedia holiday?
Most definitely. Expedia has over 400 airline partners to choose from worldwide. With such a big range of choices, finding the ideal carrier to fly you to Los Santos will be a breeze.

Stay near popular Los Santos attractions

A beach with a flock of seagulls on the sand and the ocean in the background.

Playa El Arenal

8.6/10 (55 reviews)
If a restful holiday is part of your travel plans, Playa El Arenal might be the perfect place to visit during your trip to Pedasí.
See properties
Colorful thatched-roof huts, a swimming pool, and a tropical landscape.
Photo by Isa

Los Destiladeros Beach

8.8/10 (45 reviews)
If a restful holiday is part of your travel plans, Los Destiladeros Beach might be the perfect place to visit during your trip to Punta Mala.
See properties

Venao Beach

9.2/10 (137 reviews)
If a restful holiday is part of your travel plans, Venao Beach might be the perfect place to visit during your trip to Las Escobas del Venado. You can seek out the surfing spots while in the area.
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Playa El Toro

7.8/10 (42 reviews)
Why not spend a care-free afternoon at Playa El Toro during your travels in Pedasí?
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El Uverito Beach

8.6/10 (22 reviews)
Why not spend a care-free afternoon at El Uverito Beach during your travels in Las Tablas? Wander the seaside and parks while you're in the area.
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Playa Las Comadres

6.6/10 (12 reviews)
Why not spend a care-free afternoon at Playa Las Comadres during your travels in Las Tablas? Wander the seaside and parks while you're in the area.
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Iguana Island National Park

9.2/10 (48 reviews)
Explore the great outdoors at Iguana Island National Park, a lovely green space in Isla Iguana.
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What to do in Los Santos

Canopy Zipline from Playa Venao

Canopy Zipline from Playa Venao

£48
per adult
Canopy Zipline from Playa Venao
Playa Venao: Island Snorkeling Tour

Playa Venao: Island Snorkeling Tour

£69
per adult
Playa Venao: Island Snorkeling Tour
See all activities in Los Santos

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.