Los Santos Holidays

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Your Los Santos Holiday

Unlock the door to adventure with a holiday package to Los Santos. Get your journey underway in Guarare, where its festivals will be among the things that make this city stand out. Why not plan your trip to Los Santos around its most well-known cities? Las Escobas del Venado, Pedasi and Las Tablas are all fantastic places to start. Expedia has everything you need when it comes to planning your Los Santos holiday. From hotels and flights, to activities and more, we're here to help you create a travel experience like no other.

Top destinations in Los Santos

FlightsFlightsHotelsHotels

Pedasí

Pedasí
FlightsFlightsHotelsHotels

Punta Mala

Punta Mala

Top Los Santos Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was £977, price is now £799 per person
£799
per person
27 Jul - 31 Jul
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.6/10 Exceptional! (285 reviews)
Excellent hotel, very clean wonderful staff. Good location

Reviewed on 30 Apr 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was £1,281, price is now £906 per person
£906
per person
27 Jul - 31 Jul
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.2/10 Wonderful! (1,009 reviews)
The hotel was very safe and comfortable. Lots of places to eat and shop within walking distance. Easy to get transportation to sightseeing.

Reviewed on 2 May 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was £1,059, price is now £810 per person
£810
per person
27 Jul - 31 Jul
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
Just came back home stayed 4 night and from time I arrive till I left I had a great experience food was really good in there restaurants staff was polite and helpful. And hotel was clean and well maintained room service was done regularly to ensure clean towels and bed sheets. Definitely would recommend and revisit💯💯💯

Reviewed on 1 May 2026

Hilton Panama

Hilton Panama

5 out of 5
Bella Vista
Price was £1,087, price is now £862 per person
£862
per person
27 Jul - 31 Jul
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9/10 Wonderful! (1,007 reviews)
First class hotel in downtown with excellent view from pool and restaurant area on high floor (really pleasant at night). Many dining options and not far from Panama Canal and old city.

Reviewed on 30 Apr 2026

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Price was £1,203, price is now £979 per person
£979
per person
27 Jul - 31 Jul
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
7.6/10 Good! (1,002 reviews)
We loved Dreams. The food and drinks were delicious. The property is beautiful and well maintained. Wish we could have stayed longer.

Reviewed on 22 Apr 2026

Los Santos Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Top Sights
Venao Beach, El Uverito Beach and Playa Las Comadres

Top hotels in Los Santos

Selina River Venao

Selina River Venao

3 out of 5
Belisario Porras Avenue Las Escobas del Venado Provincia de Herrera
Fully refundableReserve now, pay when you stay
The price is £60 per night from 5 May to 6 May
£60
5 May - 6 May
includes taxes & fees
8.2/10 Very Good! (21 reviews)
The room was

Reviewed on 21 Jan 2026

Selina River Venao
Selina Playa Venao - Hostel

Selina Playa Venao - Hostel

3 out of 5
Playa Venao 1 Las Escobas del Venado Los Santos
Fully refundableReserve now, pay when you stay
The price is £79 per night from 4 May to 5 May
£79
4 May - 5 May
includes taxes & fees
Selina Playa Venao - Hostel
Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Playa Venao Las Escobas del Venado Los Santos
Fully refundableReserve now, pay when you stay
The price is £107 per night from 11 May to 12 May
£107
11 May - 12 May
includes taxes & fees
9/10 Wonderful! (157 reviews)
The Villa Marina Hotel is an older property with only nine rooms. Overall the property is nice and well maintained. With the price they can’t invest a great amount in the infrastructure and stay in business. The grass area would benefit from expansion, this would reduce mud; between mud and black ...

Reviewed on 25 Apr 2026

Villa Marina Hotel
See all 371 properties in Los Santos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

Why should I book my Los Santos holiday with Expedia?
Expedia has you covered for all aspects of your next Los Santos holiday. You'll always get the best prices around, but when you bundle your airfares, accommodation and/or hire car into a holiday package, you'll score even bigger savings. Looking to really make the most of your stay? Add some activities and tours to your package. We offer flexible cancellation policies on almost all bookings, so there's no need to stress if your plans change. Head over to our Customer Service Portal link to find out more.
When is the best time of year to holiday in Los Santos?
Los Santos can get busy in January, March and May, so if you want to steer clear of the crowds, visit in June, July and December. To get an idea of the type of weather you can experience, the average daytime temperature in January, the coolest month in Los Santos, is 25ºC. The warmest month here is February, when temperatures average 26ºC.
What are the top hotels for my holiday in Los Santos?
Hotel El Sitio Playa Venao and Hostal Pachamama know how to make their guests feel at home in Las Escobas del Venado. If your itinerary also includes Pedasi, take a look at Hotel Punta Franca and Hotel El Sitio Playa Venao. Both are popular with travellers.
How do I get a cheap holiday to Los Santos?
Find flights that fit your schedule, add a hotel to your booking and watch the savings pile up with a Los Santos holiday. It's that simple! From flights and hotels to activities and hire cars, Expedia is where your cheap getaway begins. And with more than 400 partner airlines and 321,000 properties across the globe to choose from, you'll never be short of choice. Learn more about how you can save money on your next holiday when you book a flight and hotel together with Expedia.
What should I do on my Los Santos holiday?
You'll find plenty of things to put on your itinerary during your holiday in Los Santos. Venao Beach, El Uverito Beach, Playa El Toro and Los Destiladeros Beach are among the leading attractions.
Do I need a visa for my Los Santos holiday?
Official government websites have all the information you need on visa requirements, application procedures and any necessary documentation. Your nationality and the purpose of your visit, whether it be for work or pleasure, will determine if you need a visa for Los Santos. Also be sure that your passport is up to date and has at least six months validity remaining after your planned date of return. Finalise all your travel planning well ahead of time to avoid any last-minute surprises.
What should I wear on my Los Santos holiday?
Think about the types of things you'll be doing during your Los Santos holiday and travel with pieces that you can easily mix and match. For fashion inspiration or even information on dress codes, look up style blogs or social media accounts. It's also wise to monitor the forecast so you can pack appropriately. February is the warmest month in Los Santos, with average temperatures of 26ºC. January is when much of this destination is at its coolest, so get packing to suit daily temperatures of around 25ºC.
What does an Expedia Los Santos holiday include?
Flights, hotels and a cool set of wheels for all your fun road trip adventures. Simply mix and match your favourite bundle and gain access to great discounts. Once you've made your booking, add on a couple of tours and experiences and watch your savings pile up. When it comes to planning your Los Santos break, you're the one in control! Expedia offers a wide range of properties in Los Santos, giving you the flexibility to tailor your escape. Private holiday homes and villas are two of the most in-demand stays for our guests here.
Does Expedia offer Book Now, Pay Later Los Santos holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book an incredible getaway without eating away at your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Klarna offers easy monthly payment plans that suit all types of budgets, so you can have that well-deserved holiday sooner.
  • No-deposit holidays: Clicking on the "book now" button is much easier with this payment plan. With no deposit required for your escape, you can Book Now, Pay Later and start working on your travel itinerary.

Can I choose my airline with a Los Santos Expedia holiday?
Most definitely. Expedia has over 400 airline partners to choose from worldwide. With such a big range of choices, finding the ideal carrier to fly you to Los Santos will be a breeze.

Popular places to visit

Guanico Abajo Beach

If a restful holiday is part of your travel plans, Guanico Abajo Beach might be the perfect place to visit during your trip to Guanico Abajo.

Guanico Abajo Beach

What to do in Los Santos

Playa Venao: Island Snorkeling Tour

Playa Venao: Island Snorkeling Tour

£69
per adult
Playa Venao: Island Snorkeling Tour
See all activities in Los Santos

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.