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Our top choices for Santo Domingo hotels

Casa Loma

Casa Loma
3.0 star property
Pedasí
8.0 out of 10, Very good, (51 reviews)
"Friendly breakfast staff"
Canada
Gordon J
The price is £45
includes taxes & fees
17 Apr - 18 Apr
Casa Loma

Pedasi Sport Club

Pedasi Sport Club
3.0 star property
Pedasí
8.2 out of 10, Very good, (56 reviews)
"Good place to stop. Everything is with in walking distance. "
United States
Robin
The price is £58
includes taxes & fees
18 Apr - 19 Apr
Pedasi Sport Club

Hotel Presidente

Hotel Presidente
3.5 star property
Las Tablas
9.0 out of 10, Wonderful, (124 reviews)
"We have returned each time we come to visit the area as the staff are professional, friendly, and helpful. Highly recommend!"
United States
Melissa
The price is £65
includes taxes & fees
20 Apr - 21 Apr
Hotel Presidente

La Placita - Apartamentos

La Placita - Apartamentos
2.0 star property
Las Tablas
9.0 out of 10, Wonderful, (2 reviews)
"I never had contact until i was leaving. Which was perfect, because during my stay i never needed anything nor had reason to complain."
United States
Jeffrey
The price is £80
includes taxes & fees
19 Apr - 20 Apr
La Placita - Apartamentos

Hotel Faranda Guayacanes, a member of Radisson Individuals

Hotel Faranda Guayacanes, a member of Radisson Individuals
3.0 star property
Chitre
8.0 out of 10, Very good, (319 reviews)
"The room was spotless and the staff were wonderful. I will stay at the hotel again. "
United States
Gordon
The price is £62
includes taxes & fees
19 Apr - 20 Apr
Hotel Faranda Guayacanes, a member of Radisson Individuals

Casa Magna Panama

Casa Magna Panama
1.0 star property
Las Tablas
9.6 out of 10, Exceptional, (5 reviews)
"The place exceed my expectations. Definitely, I will return and I recommend it."
United States
Rosmery I
The price is £58
includes taxes & fees
24 Apr - 25 Apr
Casa Magna Panama

Hostel Villas De Zianit

Hostel Villas De Zianit
2.0 star property
Guarare
10.0 out of 10, Exceptional, (2 reviews)
"I had a great stay yesterday at their home. They treated me like a relative gave me a free meal and answered all my questions. Your accommodations were excellent and I would definitely go back. High recommendations for sure way friendly couple!"
United States
Dennis
The price is £37
includes taxes & fees
17 Apr - 18 Apr
Hostel Villas De Zianit

Hostal Casa de Quincha

Hostal Casa de Quincha
1.0 star property
Las Tablas
The price is £34
includes taxes & fees
17 Apr - 18 Apr
Hostal Casa de Quincha
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Santo Domingo?
The best area to stay in Santo Domingo, Los Santos, Panama, is the Colonial Zone (Zona Colonial).

The Colonial Zone is the historic heart of the city, a UNESCO World Heritage site known for its well-preserved Spanish historic architecture, cobblestone streets, and charming plazas. It's a highly walkable district, with many of the city's most important landmarks, such as the Alcázar de Colón and the Catedral Primada de América, situated within a few blocks of each other. Calle El Conde is a pedestrian street that runs through the centre, offering shops, restaurants, and street performers.

Couples will find the Colonial Zone particularly appealing for its romantic ambiance. You can enjoy strolls through historic squares like Parque Colón, dine at restaurants with outdoor seating, and discover hidden courtyards. Many boutique hotels are housed in renovated historic buildings, offering a unique and intimate stay.

For solo travellers, the Colonial Zone offers a convenient and engaging base. Its central location means easy access to public transport for exploring other parts of the city, and there are numerous cafes and bars to relax in.
When is the best time to go to Santo Domingo?
The best time to visit Santo Domingo, Los Santos, Panama, is during the dry season, which runs from December to April.

This period offers consistently sunny weather with lower humidity and very little rain, making it ideal for exploring the town and enjoying the nearby beaches. You'll find it comfortable for walking around and experiencing local life without the interruption of daily downpours.

For those looking to experience local culture and festivities, February is a particularly good month to visit, as it hosts the traditional Las Tablas Carnival. This lively event showcases vibrant parades and celebrations, offering a unique insight into Panamanian traditions. However, be aware that accommodation prices might be higher and availability lower during this popular festival.

If you prefer a quieter experience and don't mind occasional rain showers, the shoulder months of May and November can also be a good option. The landscape is lush, and you might find better deals on flights and hotels.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santo Domingo.
How can I save on a Santo Domingo hotel booking with Expedia?
Members always get our best prices. Find our best Santo Domingo hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Santo Domingo hotel?
Prices for hotels in Santo Domingo often vary, but you can find a great deal from £34 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.