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Top Cities to Visit in Panama

Panama City
Cheap round-trip flights to Panama
Prices were available within the past 7 days and start at £407 for one-way flights and £583 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Trending flights to Panama
These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

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Get ready to fly to Panama
Prepare your luggage and book your flights to Panama with Expedia. We offer a seamless flight booking experience, with a wide range of Panama plane tickets to choose from. If you need help finding some of the best deals for cheap flights to Panama in 2025, we are always available to assist you. Book your flights to Panama today and let the adventure begin!
Find the best tickets to Panama
To find some of the best tickets to Panama in 2025, use Expedia's powerful search engine to compare dates and the different departure and arrival airports for your trip. Whether you're after direct flights to Panama or last-minute flights to Panama, you can filter and sort your search results, making it easy to find the ideal flight to Panama.
Airlines fly to Panama
There are 20 different airlines that fly to Panama including some of the most trusted names in the business. To book flights to Panama with your favourite airline, take a look at Expedia's flight listings and try out different dates to find some of the best Panama plane tickets.
Find the cheapest flights to Panama
By booking early you may find some of the best deals for Panama flights from the UK, including Panama direct flights. You can usually find affordable and cheap flights to Panama, whether one-way from £407 or round-trip from £583, with Expedia if you book your trip far enough in advance.
Find the best airports for cheap flights to Panama
Try searching for different Panama airports with Expedia to find some of the cheapest flights to Panama. Flights from London (LGW) to Panama City (PTY) usually have the lowest price from £407.
Why book your flights to Panama with Expedia
Expedia offers great deals on Panama air fares from £407 to cater to every budget. Not only is Expedia one of the top platforms to book flights to Panama from the UK, it is also your one-stop shop for booking hotels, car rentals, and more.
*Prices and availability are subject to change. Additional terms apply.
Travel information
Travel information
Airlines serving | Air Europa, Iberia, avianca, KLM, Air France, Swiss International Air Lines, United, British Airways |
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Roundtrip price | from £583 |
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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Top Panama Hotels
- Hotel Riu Plaza Panama
- Crowne Plaza Panama Airport by IHG
- Dreams Playa Bonita Panama - All Inclusive
- Riande Urban Hotel
- JW Marriott Panama
- The Westin Playa Bonita Panama
- Grand Decameron Panama, A Trademark All Inclusive Resort
- Sheraton Grand Panama
- Principe Hotel and Suites
- Plaza Paitilla Inn Hotel
- Marriott Panama Hotel
- W Panama
- Hotel Riu Playa Blanca - All Inclusive
- The Executive Hotel
- Megapolis Hotel Panamá
- Novotel Panama City
- Decapolis Hotel Panama City
- TRYP by Wyndham Panamá Centro
- Hotel Ojos del Rio