Title: Los Santos Casino Hotels, Panama: Los Santos Hotel Guide | Expedia.co.uk [Los Santos Travel Guide](https://expedia.co.uk/Los-Santos.dx6246240)[Los Santos Hotels](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Hotel-Destinations)[Holiday Rentals in Los Santos](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Holiday-Rental-Destinations)[Los Santos Flights](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Flight-Destinations)[Los Santos Car Hire](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Car-Hire-Destinations)[Los Santos Holidays](https://expedia.co.uk/Los-Santos.d6246240.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/9/06f60e4c93e3996e5ea4a5b09f97584c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Casino Hotels in Los Santos ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Los Santos Casino Hotels Tonight [2 Oct - 3 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-10-02&endDate=2025-10-03&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Oct - 4 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-10-03&endDate=2025-10-04&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Los Santos Casino Hotels ![Aerial view](https://images.trvl-media.com/lodging/7000000/6420000/6410300/6410225/04716fd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/7000000/6420000/6410300/6410225/00e517f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Bedroom | Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/7000000/6420000/6410300/6410225/949eb32e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/7000000/6420000/6410300/6410225/9b8359c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Venao Hotel Resort Las Escobas del Venado 9.0/10 Wonderful (141) "Was very nice location and our room was great " £111 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Las-Escobas-Del-Venado-Hotels-Playa-Venao-Hotel-Resort.h6410225.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17®ionId=6246240&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Casino-Hotel.0-0-d6246240-tCasinoHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Casino-Hotel.0-0-d6246240-tCasinoHotel.Hotel-Filter-Destinations) ## Top Los Santos Hotel Reviews ![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](//images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/11d8f39d_y.jpg) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection 10/10 Excellent "Excellent all around" [](https://expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](//images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "Good" [](https://expedia.co.uk/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ![Hotel Presidente](//images.trvl-media.com/lodging/16000000/15620000/15615000/15614946/8b2929d2_y.jpg) ### Hotel Presidente 10/10 Excellent "Outstanding hotel!!! Excellent service!!! Great food!!!" [](https://expedia.co.uk/Las-Tablas-Hotels-Hotel-Presidente.h15614946.Hotel-Information) ![Playa Blanca Beach Resort - All Inclusive](//images.trvl-media.com/lodging/1000000/970000/967200/967117/39c2572a_y.jpg) ### Playa Blanca Beach Resort - All Inclusive 10/10 Excellent "Safe áreas , excelente customer services,recreation team super good ,the común áreas and pools needs paint " [](https://expedia.co.uk/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information) ![Hotel Posada Destiladeros](//images.trvl-media.com/lodging/12000000/11840000/11838000/11837980/0e32d678_y.jpg) ### Hotel Posada Destiladeros 10/10 Excellent "The sea view was amazing and it had easy access to the beach. The breakfast was lovely. The hosts are very helpful. The restaurant evening meal was wonderful, we had fresh fish and shrimp. A good selection of drinks was also available. A short drive from Pedasi. We also saw a yellow caracara at breakfast as well as a black vulture." [](https://expedia.co.uk/Punta-Mala-Hotels-Hotel-Posada-Destiladeros.h11837980.Hotel-Information) ![Hotel Cubitá Boutique Resort & Spa](//images.trvl-media.com/lodging/10000000/9680000/9675400/9675316/9ea589c5_y.jpg) ### Hotel Cubitá Boutique Resort & Spa 10/10 Excellent "Staff was lovely. Will be back soon. " [](https://expedia.co.uk/La-Arena-Hotels-Hotel-Cubita.h9675316.Hotel-Information) ![Hotel Punta Franca](//images.trvl-media.com/lodging/12000000/11300000/11295600/11295531/w750h558x0y0-43779190_y.jpg) ### Hotel Punta Franca 10/10 Excellent "The place is on top of a hill which gives you an spectacular ocean view. In the morning you can hear birds and the amazing sound of the ocean waves below. It is a place to enjoy nature, views, tranquility, the beach, sand, just to breathe fresh air. It’s a quiet atmosphere, not a party place. I love this quietness and I will come back soon. The staff is super friendly and welcoming. There is no refrigerator in the room, so i guess we better bring a cooler with ice next time. It’s really an amazing experience in Playa Destiladeros, Pedasi " [](https://expedia.co.uk/Punta-Mala-Hotels-Hotel-Punta-Franca.h11295531.Hotel-Information) ![ Grand Decameron Panama, A Trademark All Inclusive Resort](//images.trvl-media.com/lodging/1000000/980000/976000/975964/0a66855c_y.jpg) ### Grand Decameron Panama, A Trademark All Inclusive Resort 10/10 Excellent "The best option for family trip." [](https://expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information) ![Hotel Faranda Guayacanes, a member of Radisson Individuals](//images.trvl-media.com/lodging/1000000/980000/971000/970914/2fd85024_y.jpg) ### Hotel Faranda Guayacanes, a member of Radisson Individuals 10/10 Excellent "Beautiful grounds, friendly staff, very good restaurant " [](https://expedia.co.uk/Chitre-Hotels-Hotel-Faranda-Guayacanes.h970914.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - [4 Star Hotels in La Palma](https://www.expedia.co.uk/4Star-La-Palma-Hotels.s40-0-d553248634761867191.Travel-Guide-Filter-Hotels) - [Canas Hotels](https://www.expedia.co.uk/Canas-Hotels.d553248623859250109.Travel-Guide-Hotels) - [Guarare Hotels](https://www.expedia.co.uk/Guarare-Hotels.d3000387438.Travel-Guide-Hotels) - [Hotels near Iguana Island National Park](https://www.expedia.co.uk/Iguana-Island-National-Park-Hotels.0-l6286174-0.Travel-Guide-Filter-Hotels) - [Resorts in Isla Canas](https://www.expedia.co.uk/Isla-Canas-Hotel-Resorts.d6286066-aaHotelResorts.Travel-Guide-Accommodation) - [Isla Iguana Hotels](https://www.expedia.co.uk/Isla-Iguana-Hotels.d553248623461873998.Travel-Guide-Hotels) - [La Palma Hotels](https://www.expedia.co.uk/La-Palma-Hotels.d553248634761867191.Travel-Guide-Hotels) - [La Villa de los Santos Hotels](https://www.expedia.co.uk/La-Villa-De-Los-Santos-Hotels.d553248623140686317.Travel-Guide-Hotels) - [Las Escobas del Venado Hotels](https://www.expedia.co.uk/Las-Escobas-Del-Venado-Hotels.d6336814.Travel-Guide-Hotels) - [Las Tablas Hotels](https://www.expedia.co.uk/Las-Tablas-Hotels.d6347532.Travel-Guide-Hotels) - [Ojo de Agua Hotels](https://www.expedia.co.uk/Ojo-De-Agua-Hotels.d553248623859250163.Travel-Guide-Hotels) - [Pedasí Hotels](https://www.expedia.co.uk/Pedasi-Hotels.d6130073.Travel-Guide-Hotels) - [Hotels near Playa El Toro](https://www.expedia.co.uk/Playa-El-Toro-Hotels.0-l6286158-0.Travel-Guide-Filter-Hotels) - [Santo Domingo Hotels](https://www.expedia.co.uk/Santo-Domingo-Hotels.d553248623199120260.Travel-Guide-Hotels) - [Flights to Las Tablas](https://www.expedia.co.uk/Cheap-Flights-To-Las-Tablas.d6347532.Travel-Guide-Flights) - [Flights to Pedasí](https://www.expedia.co.uk/Cheap-Flights-To-Pedasi.d6130073.Travel-Guide-Flights) - [Visit Guarare](https://www.expedia.co.uk/Guarare.dx3000387438) - [Visit Isla Canas](https://www.expedia.co.uk/Isla-Canas.dx6286066) - [Isla Iguana Holidays](https://www.expedia.co.uk/Isla-Iguana.d553248623461873998.Holidays-City-Breaks) - [Visit Las Escobas del Venado](https://www.expedia.co.uk/Las-Escobas-Del-Venado.dx6336814) - [Pedasí Holidays](https://www.expedia.co.uk/Pedasi.d6130073.Holidays-City-Breaks) - [Visit Pedasí](https://www.expedia.co.uk/Pedasi.dx6130073) - [Avis Rental Cars in Isla Canas](https://www.expedia.co.uk/Avis-Car-Rentals-In-Isla-Canas.d6286066-c41.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Isla Canas](https://www.expedia.co.uk/Thai-Cars-Car-Rentals-In-Isla-Canas.d6286066-c1027.Car-Rental-Guide-Suppliers)