Title: Panama Casino Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Casino-Hotel.0-0-d2897-tCasinoHotel.Travel-Guide-Filter-Hotels) ![Adobe](https://images.trvl-media.com/place/6023445/756687f1-f5d2-4c5e-80bf-e3d7aa95a03c.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Casino-Hotel.0-0-d6023445-tCasinoHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Casino Hotels Tonight [10 Feb - 11 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-10&endDate=2026-02-11&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-11&endDate=2026-02-12&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-13&endDate=2026-02-15&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-20&endDate=2026-02-22&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama hotels with a casino ![Casino](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/446f07ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/c1888432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/9750e503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/67ba0beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waymore Hotel Spa and Casino [](https://www.expedia.co.uk/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information) Bella Vista 6.2/10 (1,000 reviews) "It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldo [](https://www.expedia.co.uk/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Partial Ocean View | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/2c21fbc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,006 reviews) "Beautiful hotel, great service. Breakfast buffet is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara £232 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/da360084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Bella Vista 8.8/10 Excellent (1,008 reviews) "Resteraunts, location, rooms all very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanne £128 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/d8f830ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/7dd77106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; sushi ](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/32027b12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Ocean View | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/2f26d3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Decapolis Hotel Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) San Francisco 8.6/10 Excellent (1,548 reviews) "Nice comfortable hotel and very friendly staff." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) norah £91 includes taxes & fees 28 Feb - 1 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/dcfb3e61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/7368cd10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/ca08becf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) San Francisco 8.4/10 Very good (1,001 reviews) "Great stay! Very safe!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARVIN [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/4235e7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9e56ccf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/a2139207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; pool views ](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/5ca43e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Panama City Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) Bella Vista 8.8/10 Excellent (147 reviews) "Very good hotel, well located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrés £102 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/8794e486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Bella Vista 8.8/10 Excellent (1,007 reviews) "Huge hotel wit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katya £169 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/03c93438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/a1ed65f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Studio, 1 King Bed with Sofa bed, Balcony | Balcony](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/6c8d5508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/31671e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Casino Central Park Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Y-Casino-Central-Park-Panama.h4624380.Hotel-Information) Bethania 7.6/10 Good (435 reviews) "Great service, clean, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EDGAR £52 includes taxes & fees 19 Feb - 20 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Y-Casino-Central-Park-Panama.h4624380.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/dc6a5657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/700fef33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/88cca748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) Tocumen 8.6/10 Excellent (1,863 reviews) "Very nice staff and confortable stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARIA £101 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![On the beach, white sand, free beach cabanas, sun-loungers](https://images.trvl-media.com/lodging/1000000/980000/976000/975964/ba50eb15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![9 restaurants, breakfast, lunch, dinner served; seafood ](https://images.trvl-media.com/lodging/1000000/980000/976000/975964/61f60128.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976000/975964/db902bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![9 restaurants, breakfast, lunch, dinner served; seafood ](https://images.trvl-media.com/lodging/1000000/980000/976000/975964/4a08ec2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Decameron Panama, A Trademark All Inclusive Resort [](https://www.expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information) Rio Hato 7.2/10 Good (1,006 reviews) "Great hotel great hospitality " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Marie-Christine £158 includes taxes & fees 12 Mar - 13 Mar [](https://www.expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-25&endDate=2026-02-26®ionId=142&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Casino-Hotel.0-0-d142-tCasinoHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Casino-Hotel.0-0-d142-tCasinoHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Room was always clean. Staff was courteous it was also close proximity to Multiplaza mall which was great. Breakfast was ok. " [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Everything was great, the food, room amenities and location " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Gran Evenia Bijao & Convention Center](https://images.trvl-media.com/lodging/73000000/72100000/72094600/72094557/bafae9a3_y.jpg) ### Gran Evenia Bijao & Convention Center 10/10 Excellent "Staff very helpful and kind. Food very nice as well rooms and amenities." [](https://expedia.co.uk/Rio-Hato-Hotels-Bijao-Beach-Resort.h72094557.Hotel-Information) ![Hotel Ojos del Rio](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/4e16d91f_y.jpg) ### Hotel Ojos del Rio 10/10 Excellent "The staff, the food and the room and all. " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Staff was great, rooms were ok and clean. Breakfast was good, coffee fresh and hot at anytime so overall excellent stay. Did advertise an airport shuttle which was not available, but taxis @ 30 were available. " [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "we got a nice upgrade. room was great. " [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![ Grand Decameron Panama, A Trademark All Inclusive Resort](https://images.trvl-media.com/lodging/1000000/980000/976000/975964/0a66855c_y.jpg) ### Grand Decameron Panama, A Trademark All Inclusive Resort 10/10 Excellent "Habitación amplia y limpia con excelente balcón. Alimentos abundantes y agradables, bebidas alcohólicas, entretenimiento, show, playa. Excelente. Muy buena alternativa, lo recomiendo " [](https://expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The room was clean, staff were nice, service was excellent! Definitely recommend " [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Yes the room was very clean and spotless " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information)