Title: Panama Safari Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk

[Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks)

![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by PhotoJoy

# Search Safari Hotels in Panama

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## Panama Accommodation: Most Popular Cities to Stay

![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.co.uk/Panama-City-Hotels-Safari-Hotel.0-0-d2897-tsafarihotel.Travel-Guide-Filter-Hotels)

## Check availability on Panama Safari Hotels

Tonight

[31 Dec - 1 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-12-31&endDate=2026-01-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[1 Jan - 2 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-01&endDate=2026-01-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama hotels with on-site safari

![On the beach, white sand](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006774/1094ce19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Yoga](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006774/w748h563x0y6-2fae7d05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006774/19a1546a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006774/527a916b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Playa Bluff Hotel

[](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Playa-Bluff-Lodge.h16006774.Hotel-Information)

Bocas del Toro

7.8/10

Good

(34)

"Booked and paid for an ocean view room with a balcony but only garden view rooms were available so instead of the waves crashing I heard the property next door doing Los construction all day long …. Other than that the place was great "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wendy

£85

includes taxes & fees

7 Jan - 8 Jan

[](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Playa-Bluff-Lodge.h16006774.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/0d6dbc5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/daf15c9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/be207e74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gamboa Rainforest Reserve

[](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information)

Colon

7.8/10

Good

(674)

"Staff are amazing. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Mary

£99

includes taxes & fees

11 Jan - 12 Jan

[](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Panama Hotel Reviews

![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg)

### Marriott Panama Hotel

10/10 Excellent

"RewriteWonderful hotel with great staff. I particularly want to shout out Karen. What a lovely front desk staff. Very accomodating and she did it with a smile. The location was perfect. Although not in Casco Viejo, it was only like a $4 uber ride away. It is connected to the Albrook mall which has lots of shopping and food. Will definitely stay here again. However pool was small and extremely crowded"

[](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg)

### Crowne Plaza Panama Airport by IHG

10/10 Excellent

"Good"

[](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"Rooms are clean. Staff is great. "

[](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg)

### Megapolis Hotel Panamá

10/10 Excellent

"Check in took over an hour! "

[](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information)

![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg)

### Dreams Playa Bonita Panama - All Inclusive

10/10 Excellent

"Amazing staff - Every person I came in contact with was friendly and helpful. "

[](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"The room was very spacious and modern, surpassed my expectations!"

[](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"The staff were very friendly. The room was cleaned on time. They even gave me a little gift for my birthday, which I was surprised and impressed!"

[](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"nice staff. Huge room. Ice maker would be nice."

[](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg)

### JW Marriott Panama

10/10 Excellent

"All of it Fantastic "

[](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)