A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City Safari Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Panama City hotels with on-site safari

A view from a balcony with a cityscape in the background, featuring tall buildings and a body of water.

1. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,235 reviews)
"Nice place close to everything."
United States
Rene
The price is £103
includes taxes & fees
30 Nov - 1 Dec
Plaza Paitilla Inn Hotel
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

2. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (495 reviews)
"Enjoyed our stay"
United States
Mariah
The price is £188
includes taxes & fees
1 Nov - 2 Nov
Hyatt Regency Panama City
A multi-story building with balconies, large windows, and a clear blue sky.

3. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (206 reviews)
"Great food and location"
United States
James
The price is £125
includes taxes & fees
2 Nov - 3 Nov
Las Clementinas
A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.

4. Gran Evenia Panama

Gran Evenia Panama
4.5 star property
Bella Vista
9.2 out of 10, Wonderful, (254 reviews)
"Had a wonderful stay, close walking food area and not too far from the mall"
United States
Johneil
The price is £82
includes taxes & fees
1 Nov - 2 Nov
Gran Evenia Panama
A hotel entrance with a covered walkway, large windows, and a well-maintained garden area.

5. Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (600 reviews)
"Hotel is maintained and managed well, close to many restaurants and transportation."
United States
Michael
The price is £33
includes taxes & fees
2 Nov - 3 Nov
Hotel Milan
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

6. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,000 reviews)
"was good"
United States
Juliet
The price is £174
includes taxes & fees
13 Nov - 14 Nov
Bristol Panama, a Registry Collection Hotel
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

7. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (6,145 reviews)
"Great clean hotel! Very nice location"
Canada
Sean
The price is £116
includes taxes & fees
23 Nov - 24 Nov
Hotel Riu Plaza Panama
A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

8. Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista
9.4 out of 10, Exceptional, (28 reviews)
"Everything was great!! Would definitely book again on my next trip to Panamá"
United States
Sheena
The price is £112
includes taxes & fees
1 Nov - 2 Nov
Yoo Apartamento
A hotel room with two beds, a large window with curtains, and abstract wall art.

9. TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"I love the tryp i was well taken care of and thank you expedia for my voucher ."
United States
Bert
The price is £73
includes taxes & fees
15 Nov - 16 Nov
TRYP by Wyndham Panamá Centro
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

10. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is £112
includes taxes & fees
31 Oct - 1 Nov
La Résidence Panamá
A rooftop pool with sun loungers and a city skyline in the background.

11. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,220 reviews)
"Breakfast, Cafe, was just perfect location"
United States
Bruno
The price is £112
includes taxes & fees
31 Oct - 1 Nov
Waymore Hotel Spa & Casino
A high-rise building with a rooftop pool area, surrounded by other buildings.

12. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
"Had an amazing trip, the staff were amazing!!!"
United States
Naomi
The price is £206
includes taxes & fees
13 Nov - 14 Nov
W Panama
A hotel entrance with a glass door, a chandelier, and a wall of greenery.

13. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,039 reviews)
"Good breakfast and staff"
United States
Travis
The price is £66
includes taxes & fees
1 Nov - 2 Nov
Riande Urban Hotel
A modern hotel pool area with lounge chairs and a clear view of the ocean.

14. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
"Perfect location close to the financial district, local markets, and great restaurants."
United States
Simon
The price is £216
includes taxes & fees
20 Nov - 21 Nov
Hilton Panama
A hotel room with a large bed, a desk, a chair, a sofa, and a view of the cityscape.

15. Hotel Mio Panama

Hotel Mio Panama
3.0 star property
Bella Vista
8.8 out of 10, Excellent, (283 reviews)
"Great place and great location"
United States
Nfamory
The price is £49
includes taxes & fees
5 Nov - 6 Nov
Hotel Mio Panama
A spacious lobby with a chandelier, seating area, and a large mirror.

16. Hotel Coral Suites

Hotel Coral Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,002 reviews)
"Great hotel."
Canada
peter
The price is £59
includes taxes & fees
30 Nov - 1 Dec
Hotel Coral Suites
A rooftop garden with potted plants and a cityscape view.

17. Toscana Inn

Toscana Inn
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (790 reviews)
"Wonderful staff,great hotel,perfect location"
Canada
Dalton
The price is £50
includes taxes & fees
31 Oct - 1 Nov
Toscana Inn
A rooftop swimming pool with a view of high-rise buildings, a wooden deck, and a seating area with chairs and a table.

18. Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1,000 reviews)
"Good and very comfortable place to stay and close to everything"
United States
Douglas R Ng
The price is £74
includes taxes & fees
28 Nov - 29 Nov
Holiday Inn Panama Distrito Financiero by IHG
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

19. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"The room was very nice, the bar staff and front desk staff were very helpful."
United States
Oscar
The price is £234
includes taxes & fees
7 Nov - 8 Nov
Waldorf Astoria Panama
A modern building with a glass facade, a curved structure, and a flat roof.

20. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,727 reviews)
"Food was limited, but I enjoyed our stay ..3"
United States
Mechalia
The price is £72
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

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