Panama showing a beach, landscape views and tropical scenes

Search Luxury Hotels in Panama

Change your mind

Book hotels with free cancellation

Treat yourself

Save instantly and earn perks with One Key

Learn about One Key

Be picky

Search almost a million properties worldwide

Panama Accommodation: Most Popular Cities to Stay

Check availability on Panama Luxury Hotels

Tonight

Tomorrow

Next weekend

In two weeks

Top Panama Luxury Hotels

4 outdoor pools, free pool cabanas, pool umbrellas

"Always an exceptional stay. "

includes taxes & fees

16 Aug - 17 Aug

Couples treatment room(s), sauna, steam room, body treatments

"This was a amazing property extremely clean very hospitable"

includes taxes & fees

2 Sept - 3 Sept

"Lovely stay "

includes taxes & fees

16 Aug - 17 Aug

"Beautiful property and friendly staff!"

includes taxes & fees

18 Aug - 19 Aug

"2nd stay at Sortis Hotel in Panama. Never disappoints. Breakfast Buffett incredible and staff pleasant and attentive! Will stay there again!"

includes taxes & fees

10 Aug - 11 Aug

"The hotel was well maintained. The surrounding area has lots to offer in terms of food, entertainment and outdoor activities "

includes taxes & fees

23 Aug - 24 Aug

"This is THE place to stay in Panama City... it's location, friendly accommodating staff, and the amenities are fantastic. The rooms were wonderful, clean and bright. We tried Tauro (steakhouse) and the Bazaar - they were both delicious and the service excellent. We literally partied like rock stars at their rooftop restaurant, and at the wonderful outdoor infinity pool as well. We will definitely be returning! "