Title: Panama Luxury Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing a beach, landscape views and tropical scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25691-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Luxury Hotels in Panama ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Luxury-Hotel.0-0-d2897-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Luxury-Hotel.0-0-d6023445-tLuxuryHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Luxury Hotels Tonight [19 Sept - 20 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-19&endDate=2025-09-20&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-20&endDate=2025-09-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-19&endDate=2025-09-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-09-26&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Luxury Hotels ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/9a4bbb88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/22b0bcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama San Francisco 8.8/10 Excellent (1009) "The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities " £185 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/b594ef85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1008) "We had an amazing time, great hotel and great breakfast. " £140 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/cf22e531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/361a474e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/a7b599bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama Bella Vista 9.0/10 Wonderful (1003) "Great hotel for my recent stay in Panam " £181 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/19e6fda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/06af8af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/a693f2cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### American Trade Hotel Casco Viejo 9.4/10 Exceptional (560) "Lovely hotel, great dining, wonderful staff!" £204 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/7fb69592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View | City view](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/cc5e4adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, City View | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/b2066790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott Bella Vista 8.8/10 Excellent (988) "2nd stay at Sortis Hotel in Panama. Never disappoints. Breakfast Buffett incredible and staff pleasant and attentive! Will stay there again!" £121 includes taxes & fees 20 Sept - 21 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/ae99e466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/8590a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama Bella Vista 8.8/10 Excellent (1002) "Great property You don’t go wrong Amenities are great Location is perfect area safe and walkable rooms are nice large clean modern " £179 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/b225554a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/90613175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/22e383ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá San Francisco 8.4/10 Very good (1000) "This is THE place to stay in Panama City... it's location, friendly accommodating staff, and the amenities are fantastic. The rooms were wonderful, clean and bright. We tried Tauro (steakhouse) and the Bazaar - they were both delicious and the service excellent. We literally partied like rock stars at their rooftop restaurant, and at the wonderful outdoor infinity pool as well. We will definitely be returning! " [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/6bf7a38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a76722fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a7b09037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Garden Area](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a69675a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manrey Boutique Hotel Panama City 7.6/10 Good (255) [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) ![12 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/11d8f39d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/4ed0c63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 4 Bedrooms, Non Smoking, Resort View | 1 bedroom, Frette Italian sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/232137bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9ca640da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection El Chiru 9.2/10 Wonderful (661) "Spectacular hotel right in front of the beach. Extremely friendly staff. Plenty of restaurant options with top notch food. I definitely recommend it!" £127 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/d548be4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/65bd07b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | Terrace/patio](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/44769fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Americas Golden Tower Panama San Francisco 9.0/10 Wonderful (1017) "Second time staying in this wonderful hotel, and definitely we’ll stay again when back to Panama." £117 includes taxes & fees 20 Sept - 21 Sept [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04®ionId=142&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Luxury-Hotel.0-0-d142-tLuxuryHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Luxury-Hotel.0-0-d142-tLuxuryHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Next to airport and shuttle runs hourly" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "Waymore hotel is excellent " [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Great location" [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![The Executive Hotel](//images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Staff was great! I really enjoyed my stay this time. They have stepped up their game. Breakfast was good " [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Decapolis Hotel Panama City](//images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Good " [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Wonderful stay. The staff was first class and made me feel at home as a solo traveler. I got a great deal on my reservation, staying during the work week, and the value was fantastic. A great all inclusive experience. Gracias!" [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Plaza Paitilla Inn Hotel](//images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Love it" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Studio Coliving](//images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/e86f18bd_y.jpg) ### Studio Coliving 10/10 Excellent "Overall a nice place." [](https://expedia.co.uk/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) ![AC Hotel by Marriott Panama City](//images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/d365d94c_y.jpg) ### AC Hotel by Marriott Panama City 10/10 Excellent "AC Hotel is always a great stay for the money" [](https://expedia.co.uk/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information)