Title: Panama Luxury Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy # Search Luxury Hotels in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Luxury-Hotel.0-0-d2897-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Luxury-Hotel.0-0-d6023445-tLuxuryHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Luxury Hotels Tonight [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-12-20&endDate=2025-12-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [21 Dec - 22 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-12-21&endDate=2025-12-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Panama luxury hotels ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Partial Ocean View | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/2c21fbc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1002) "Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarran £243 includes taxes & fees 10 Jan - 11 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/79b76059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) Bella Vista 9.4/10 Exceptional (1000) "Great staff, super accommodating. Best place to stay in Panama!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sebastian £165 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/bd4cfae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/4a63a156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/fdcdd1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) Bella Vista 9.0/10 Wonderful (1002) "I loved everything about my stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £181 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/89b00dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/32c9362e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/af7444f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### American Trade Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) Casco Viejo 9.4/10 Exceptional (607) "Excellent service and great rooms on a beautiful and historical building" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Manuel £283 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/f6840e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Bella Vista 8.8/10 Excellent (1001) "Everything was clean and the staff was very cooperative." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deangelo £131 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/03b3b6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Bella Vista 8.8/10 Excellent (1001) "Nice room! Clean. Nice balcony, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassandra £173 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/449ce738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/7368cd10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/ca08becf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) San Francisco 8.4/10 Very good (1000) "Great stay! Very safe!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARVIN [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/6bf7a38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a76722fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a7b09037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Garden Area](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a69675a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manrey Boutique Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) Panama City 7.6/10 Good (255) "Hotel was closed when we arrived. Had not told us about the closure so we had to scramble to find another hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) ![12 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/11d8f39d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 4 Bedrooms, Resort View | Frette Italian sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/232137bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/60de636a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/23a76ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection [](https://www.expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) El Chiru 9.2/10 Wonderful (685) "Great place for a short stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeffrey £190 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/cd74829c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/e8a459e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/bfbd00a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Americas Golden Tower Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) San Francisco 9.0/10 Wonderful (1002) "I loved my stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenniffer Gonzalez De La £105 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05®ionId=142&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Luxury-Hotel.0-0-d142-tLuxuryHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Luxury-Hotel.0-0-d142-tLuxuryHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Good" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Clean room… amazing staff, breakfast was delicious our favorite hotel always " [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Amazing " [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "S" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Just wonderful hotel" [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Amazing breakfast the 1st day, ok breakfast the 2nd day. Concierge was amazing. Loved the hotel and it's smell. Absolutely recommend! Teenage kids loved it too!" [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Yes to both" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Great hotel and staff!" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Divino" [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)