Title: Panama Luxury Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Luxury-Hotel.0-0-d2897-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Luxury-Hotel.0-0-d6023445-tLuxuryHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Luxury Hotels Tonight [4 Feb - 5 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-04&endDate=2026-02-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [5 Feb - 6 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-05&endDate=2026-02-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Panama luxury hotels ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,006 reviews) "Beautiful hotel, great service. Breakfast buffet is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara £184 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/79b76059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/620cc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) Bella Vista 9.4/10 Exceptional (1,003 reviews) "All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PROBIR MAYUR £168 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/bd4cfae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/1124b3de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/cf22e531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,002 reviews) "Staff was super nice and room was great we also ate on the rooftop and food was great!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Tim £177 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/89b00dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/32c9362e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/3caa6f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### American Trade Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) Casco Viejo 9.4/10 Exceptional (655 reviews) "Perfect location with attentive staff and nice rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Negar £178 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/f6840e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Bella Vista 8.8/10 Excellent (1,004 reviews) "Resteraunts, location, rooms all very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanne £128 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/03b3b6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Bella Vista 8.8/10 Excellent (1,004 reviews) "Huge hotel wit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katya £169 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/449ce738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/ca08becf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/7368cd10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) San Francisco 8.4/10 Very good (1,001 reviews) "Great stay! Very safe!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARVIN [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/6bf7a38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a76722fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a7b09037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Garden Area](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a69675a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manrey Boutique Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) Panama City 7.6/10 Good (255 reviews) "Hotel was closed when we arrived. Had not told us about the closure so we had to scramble to find another hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) ![12 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9ca640da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/60de636a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 4 Bedrooms, Resort View | Frette Italian sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/232137bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection [](https://www.expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) El Chiru 9.2/10 Wonderful (704 reviews) "The property is beautiful and well maintained." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £164 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/e8a459e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/bfbd00a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/cd74829c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Americas Golden Tower Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) San Francisco 9.0/10 Wonderful (1,010 reviews) "excellent room and location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jon £133 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=142&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Luxury-Hotel.0-0-d142-tLuxuryHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Luxury-Hotel.0-0-d142-tLuxuryHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Everything was great@" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Everything was great SPECIALLY breakfast" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Gran Evenia Bijao & Convention Center](https://images.trvl-media.com/lodging/73000000/72100000/72094600/72094557/bafae9a3_y.jpg) ### Gran Evenia Bijao & Convention Center 10/10 Excellent "Great stuff" [](https://expedia.co.uk/Rio-Hato-Hotels-Bijao-Beach-Resort.h72094557.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "excellent room and location" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "Execellen choise for vacations" [](https://expedia.co.uk/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Always great value for the price!" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Simple, clean hotel with a good location and great value for a quick stay in Panama City." [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Nice stuff. Very welcoming and cheerful people. Clean. Closhopping centers " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The location was terrific making it easy to catch an Uber to pretty much anywhere you wanted to go. Pool & fitness area were as expected & the room was comfortable. We were here for 4 nights. Loved that it was attached to the mall." [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)