Compare and book 5 Star hotels in Rome Historic Centre, Rome

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Rome Historic Centre 5 Star Hotels

This weekend
Next weekend

Our top choices for Rome Historic Centre 5-star hotels

Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1,001 reviews)
"Amazing location in the heart of the old city and the warmest most helpful staff ever!"
United States
David
The price is £416
includes taxes & fees
27 Apr - 28 Apr
Hotel Raphaël – Relais & Châteaux

The Westin Excelsior, Rome

The Westin Excelsior, Rome
5.0 star property
Rome City Centre
8.2 out of 10, Very good, (759 reviews)
"Superb"
United States
jorge alberto
The price is £447
includes taxes & fees
27 Apr - 28 Apr
The Westin Excelsior, Rome

InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (180 reviews)
"Extraordinary location, place and quality, the room spaces and the food amazing, great for family and business"
United States
Jose Javier
The price is £607
includes taxes & fees
30 Apr - 1 May
InterContinental Rome Ambasciatori Palace by IHG

NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,000 reviews)
"Beautiful hotel, great location"
Canada
Owen
The price is £457
includes taxes & fees
21 May - 22 May
NH Collection Roma Palazzo Cinquecento

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean rooms, close to everything, in a good safe area. Breakfast was one of the best highlights of the stay."
United States
Morgan
The price is £608
includes taxes & fees
26 Apr - 27 Apr
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (533 reviews)
"Excellent location. Friendly staff and very clean rooms!!"
United States
Nelia
The price is £556
includes taxes & fees
27 Apr - 28 Apr
Baglioni Hotel Regina - The Leading Hotels of the World

W Rome

W Rome
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (212 reviews)
"We only stayed one night here before heading to the airport. The room was good, slept well and the staff very attentive. They had our taxi to the airport booked and ready the following morning."
United States
ALUN HUW
The price is £628
includes taxes & fees
27 Apr - 28 Apr
W Rome

Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (175 reviews)
"Clean, the rooftop bar is great, and the staff is very friendly and accommodating. "
United States
Summer
The price is £438
includes taxes & fees
29 Apr - 30 Apr
Radisson Collection Hotel, Roma Antica

Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (983 reviews)
"Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. "
Sweden
Daniel
The price is £490
includes taxes & fees
30 Apr - 1 May
Sofitel Rome Villa Borghese

Grand Hotel Palace Rome

Grand Hotel Palace Rome
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,001 reviews)
"The staff was amazing! Great location"
United States
Martha
The price is £223
includes taxes & fees
27 Apr - 28 Apr
Grand Hotel Palace Rome

Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World
5.0 star property
Rome City Centre
10.0 out of 10, Exceptional, (126 reviews)
"Super nice hotel, great location and very friendly staff and manager. "
United States
Ewing
The price is £544
includes taxes & fees
4 May - 5 May
Palazzo Roma - The Leading Hotels of the World

Hotel d'Inghilterra Roma - Starhotels Collezione

Hotel d'Inghilterra Roma - Starhotels Collezione
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (91 reviews)
"nice hotel"
United States
Andrei Dumitru
The price is £668
includes taxes & fees
26 Apr - 27 Apr
Hotel d'Inghilterra Roma - Starhotels Collezione

Six Senses Rome

Six Senses Rome
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (67 reviews)
"Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure."
United Kingdom
Benjamin
The price is £1,416
includes taxes & fees
7 May - 8 May
Six Senses Rome

Nobu Hotel Roma

Nobu Hotel Roma
5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (23 reviews)
"Lovely hotel, very clean and quiet room, friendly staff, good location."
United States
Denise
The price is £642
includes taxes & fees
28 Apr - 29 Apr
Nobu Hotel Roma

art’otel Rome Piazza Sallustio

art’otel Rome Piazza Sallustio
5.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (62 reviews)
"Fabulous hotel. Little bit of a hike to the core but worth it."
Canada
David Joseph
The price is £385
includes taxes & fees
26 Apr - 27 Apr
art’otel Rome Piazza Sallustio

The Rome EDITION

The Rome EDITION
5.0 star property
Rome City Centre
8.6 out of 10, Excellent, (40 reviews)
"10/10 stay absolutely gorgeous hotel, great staff and handy location. "
United Kingdom
Katherine Haidee
The price is £674
includes taxes & fees
28 Apr - 29 Apr
The Rome EDITION

Umiltà 36 - Preferred Hotels & Resorts

Umiltà 36 - Preferred Hotels & Resorts
5.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (151 reviews)
"Great location, decor lovely, friendly and helpful staff"
United States
CRAIG
The price is £753
includes taxes & fees
6 May - 7 May
Umiltà 36 - Preferred Hotels & Resorts

Aleph Rome Hotel Curio Collection by Hilton

Aleph Rome Hotel Curio Collection by Hilton
5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (480 reviews)
"Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. "
United States
Erika
The price is £450
includes taxes & fees
27 Apr - 28 Apr
Aleph Rome Hotel Curio Collection by Hilton

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (947 reviews)
"Excellent services"
United Kingdom
Jane
The price is £564
includes taxes & fees
26 Apr - 27 Apr
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (655 reviews)
"Great hotel with the best view "
United States
ghalib
The price is £468
includes taxes & fees
28 Apr - 29 Apr
Palazzo Manfredi – Small Luxury Hotels of the World
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Rome Historic Centre.
Still don't see what you're looking for?
See all properties in Rome Historic Centre.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Rome Historic Centre

Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites.

Top Rome Historic Centre Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Rome Historic Centre?
Based on reviews by our customers, Roma Luxus Hotel is one of the leading retreats for a luxurious escape in the Rome neighbourhood of Rome Historic Centre. Want more 5-star hotels around the area? NH Collection Roma Fori Imperiali and Corso 281 Luxury Suites Roma will meet your upscale desires.
How much does it cost to stay in a 5-star hotel in Rome Historic Centre?
How much you pay for a 5-star hotel in Rome Historic Centre depends on factors like when you plan to go and the length of your break. A top tip for bagging an awesome deal? Use our pricing filters to check out the available options for your selected dates.

  • Search for the lowest price per night from £233

What makes a hotel 5 stars in Rome Historic Centre?
From high-end restaurants and 24-hour fitness centres to swimming pools and dreamy bedding, the 5-star experience in Rome Historic Centre is all about comfort and luxury. But it calls for more than just upscale amenities to get a 5-star rating. Stays also have to offer remarkable guest-focused services like in-room beauty treatments, on-site laundry and dry cleaning and concierge services.

Explore a world of travel with Expedia