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This area of Rome has about 2,300,000 people.
If you want to get stuck straight into the most famed sights, St. Peter's Basilica and Roman Forum should be at the top of your list.
Reconnect with your inner-child at Rainbow MagicLand and Zoomarine. For more family fun, head onwards to the Explora Children's Museum and Hydromania.
From colourful tropical fish to underwater plant life, you can't predict what you might discover at Mediterraneum Aquarium Rome.
The kids can spend countless hours wandering around and looking over the local and exotic animals at the Bioparco di Roma and the Zoo Marine.
There's not many things more delightful than a delicious wine. Try some of the best of this region at Fontana Candida and the Gotto D'Oro-Cantina Sociale di Marino. Looking for one or two more? The La Luna del Casale and the Rutuli Vineyard are also very popular.
From amateur botanists to casual gardeners, everyone is sure to enjoy the floral specimens on display at the Botanical Gardens. The Orto Botanico and the Municipal Rose Garden are also worth a visit.
Pack a picnic basket and take some time out in the quiet, green surroundings of Villa Borghese and the Vatican Gardens. There's also plenty of space for a game or two on the grass at Parco di Villa Glori and Passeggiata del Gianicolo.
Look out over the reflective water, do some bird-watching and check for water-based activities at Lake Albano and Lake Nemi.
Turn off your phone and take a break from the noises of the modern world at Baths of Caracalla and Lupercale. Nature-loving tourists will also enjoy Parco della Caffarella and Parco Archeologico Appia Antica.
The area's exhibition spaces are brimming with interesting stories and quirky facts. Savour the quiet and relaxing atmosphere as you check out the unique collections at the MAXXI - National Museum of the 21st Century and the Museo Napoleonico. You might also want to consider a visit to the Museo degli Strumenti Musicali and the Toy Museum of Zagarolo.
The Museo delle Navi Romani will send you sailing back through the region's nautical history. Brimming with sea tales and marine artifacts, the entire crew is bound to have fun at this one.
It doesn't matter whether you are mad about science or you're just looking for something to do, you'll have a good time exploring the captivating displays at Rome Observatory and INAF Osservatorio Astronomico di Roma.
Some travellers think of natural museums as the domain of children, but the fascinating specimens at the Capitoline Museum and the Museum of Roman Civilization prove that there's more than enough to keep the adults busy too. The Crypta Balbi and the Ara Pacis are also well worth stopping by.
Rome is a frenzy of artistic activity, with galleries and exhibition spaces galore. Revel in the creative atmosphere at the Vatican Museums and the Castel Sant'Angelo. Afterwards, if you still have some energy left in the tank, wind up your afternoon at the National Gallery of Modern Art and the Borghese Gallery.
Go back through time and uncover secrets of the past at the Trajan's Market and the Montemartini Museum. The Central Museum of the Risorgimento and the Historic Museum of the Liberation are also prominent options.
Learn more about this area's past with a visit to Colosseum and the Pantheon, just two of the historical sites here. When it comes to bygone times, the stories are countless. The Spanish Steps and the Arch of Constantine are also great places to stop by.
Soak up the waterway views and architectural delights when you visit Ponte Milvio and Ponte Sisto. Ponte Sant'Angelo and Vittorio Emanuele II Bridge are two more grand structures that you could add to your to-do list.
Walk back through the mists of time and contemplate the military significance of the area. History buffs should impressed by the defensive structures at Santuario Oracolare della Fortuna Primigenia.
When it came to building and furnishing Palazzo Farnese and Palazzo Venezia, you'll see that money wasn't an issue. You may also like to walk through the leafy gardens and hear some stories at Palazzo Barberini and Palazzo Chigi.
Want to go to a place that seems like it's right out of a fairy tale? Make sure you see the area's picturesque castles. Even after all these centuries, Castello di Giulio II, Lunghezza Castle and Castle of Julius II have not lost their imposing atmosphere.
The region's spiritual side is on display at Basilica di Santa Maria Maggiore and Basilica di San Giovanni in Laterano. You could also explore Sistine Chapel and Basilica of St. Paul Outside the Walls.
Before you pack up your suitcase and head home, be sure to stop at a few of Rome's other attractions. The Parco di Roma Golf Club and the Vatican Library are certainly worth a look. Also, think about checking out the National Central Library of Rome and the Tennis Club Parioli if you can squeeze it in.
Italy's capital is an exciting and bustling city that is much-loved by travellers from near and far. With 2808 Rome hotels listed on Expedia's booking guide, finding the perfect place to stay is a breeze.
Top picks include the Rocco Forte Hotel De Russie, at Via del Babuino 9, and J.K. Place Roma, situated at Via di Monte d'Oro, 30. If you discover that those don't match your budget and style, the Villa Spalletti Trivelli or the Manfredi Luxury Apartments are two cheaper options that may be what you're looking for.
St. Peter's Basilica is on the to-do list for almost every visitor to Rome. If you'd prefer to stay close to this highly popular attraction, the Gran Meliá Rome Villa Agrippina -The Leading Hotels of the World and the Aurelia Residence are both good options.
Located in Repubblica, this family-friendly Rome hotel is steps away from Via Nazionale and Teatro dell'Opera di Roma. Colosseum and Trevi Fountain are also within 10 minutes. Repubblica - Opera House Station is only a 3-minute walk and Barberini Station is 8 minutes.
Situated near the airport, this hotel is 2.6 mi (4.3 km) from Necropoli di Porto Isola Sacra and within 6 miles (10 km) of Area Archeologica del Porto di Traiano and House of Love and Psyche. Capitolium and Case a Giardino are also within 6 miles (10 km). Fiumicino Airport Station is 9 minutes by foot.
Situated near the airport, this hotel is within 16 miles (25 km) of Castelfusano, Hydromania and Atlantico. PalaLottomatica and Euroma2 are also within 16 miles (25 km).
Situated on the waterfront, this hotel is within 1 mile (2 km) of House of Love and Psyche, Necropoli di Porto Isola Sacra and Capitolium. Case a Giardino and Grandi Horrea are also within 1 mile (2 km).
Located in Repubblica, this hotel is steps away from Via Nazionale and Teatro dell'Opera di Roma. Colosseum and Trevi Fountain are also within 10 minutes. Repubblica - Opera House Station is only a 4-minute walk and Barberini Station is 9 minutes.
Located in Repubblica, this spa hotel is within a 5-minute walk of Via Nazionale, Trevi Fountain, and Colosseum. Spanish Steps and Teatro dell'Opera di Roma are also within 10 minutes. Repubblica - Opera House Station is only a 5-minute walk and Barberini Station is 8 minutes.
Located in Rome City Centre, this hotel is within a 10-minute walk of Via Nazionale, Colosseum and Teatro dell'Opera di Roma. Trevi Fountain and Basilica di Santa Maria Maggiore are also within 15 minutes. Rome Termini Station is only a 3-minute walk and Laziali Station is 8 minutes.
Located in Vatican, this hotel is within a 15-minute walk of Castel Sant'Angelo, St. Peter's Basilica and Vatican Museums. Spanish Steps and Trevi Fountain are also within 1 mile (2 km). Ottaviano - San Pietro - Musei Vaticani Station is 7 minutes by foot and Lepanto Station is 13 minutes.