Title: TOP Shopping Hotels in Southeast Missouri, MO for 2026 | Expedia.co.uk [Southeast Missouri Travel Guide](https://expedia.co.uk/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Holiday Rentals in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Holiday-Rentals.d6058763.Travel-Guide-HolidayRentals)[Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks) ![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Bill Dillard ![](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Missouri Shopping Hotels Tonight [18 Jan - 19 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Jan - 20 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Missouri hotels with shopping nearby ![Free daily full breakfast ](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,003 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £61 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Comfort Single Room | Individually decorated, individually furnished, blackout curtains](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/5e06e6ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s play area – outdoor](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/a1c79fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/e6824269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/708e4b63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Current River Inn [](https://www.expedia.co.uk/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) Van Buren 8.2/10 Very good (165 reviews) "So convenient for us since we were paddling the Current River. Loved the old-time charm but with update amenities. Safe and walkable area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glen £74 includes taxes & fees 28 Jan - 29 Jan [](https://www.expedia.co.uk/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/1f2f3f97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/d9c7cec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/f4915375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/8ecfca12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4 [](https://www.expedia.co.uk/Ste-Genevieve-Hotels-Rivertown-Retreat-Historic-Dufour-House-Circa-1800Downtown-District-Sleeps-4.h106052541.Hotel-Information) Ste. Genevieve 10/10 Exceptional (19 reviews) "Great historic property!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rhonda R. £157 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Ste-Genevieve-Hotels-Rivertown-Retreat-Historic-Dufour-House-Circa-1800Downtown-District-Sleeps-4.h106052541.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/5c70b8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/ee42fe11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/a85f19dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/55281df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 82 Acre Hobby Farm with Lincoln Log Cabin [](https://www.expedia.co.uk/De-Soto-Hotels-82-Acre-Hobby-Farm-With-Lincoln-Log-Cabin.h73274691.Hotel-Information) De Soto 10/10 Exceptional (41 reviews) "The cabin was wonderful with many extras like snacks and coffee." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janna B. £202 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/De-Soto-Hotels-82-Acre-Hobby-Farm-With-Lincoln-Log-Cabin.h73274691.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/d1f3492c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/cf2136e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/877e8abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/07fcf4cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington [](https://www.expedia.co.uk/Farmington-Hotels-The-Hideaway-1-Charming-2-Bedroom-House-With-WiFi.h106406059.Hotel-Information) Farmington 10/10 Exceptional (13 reviews) "Great place and very comfortable! Hosts were super attentive when our door code didn’t work and got us sorted out right away. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyser B. £176 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Farmington-Hotels-The-Hideaway-1-Charming-2-Bedroom-House-With-WiFi.h106406059.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/69561cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/33842663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/afc944e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/0705ad53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cute and comfy bedroom with 1 queen bed/private bath [](https://www.expedia.co.uk/Eminence-Hotels-Cute-And-Comfy-1-Bedroom-With-1-Queen-Bedprivate-Bath.h88611645.Hotel-Information) Eminence 9.4/10 Exceptional (23 reviews) "Rebecca has a beautiful property, clean, pretty, and conveniently located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla E. £91 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Eminence-Hotels-Cute-And-Comfy-1-Bedroom-With-1-Queen-Bedprivate-Bath.h88611645.Hotel-Information) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/b5551dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/87e0f8d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/f6efa042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/da6816e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mountain View at Pickle & Perk [](https://www.expedia.co.uk/Ironton-Hotels-Mountain-View-At-Pickle-Perk.h105789927.Hotel-Information) Ironton 10/10 Exceptional (19 reviews) "Very cute place in beautiful area. Easy check-in, clean home, and comfy bed. The coffee shop below was really good with a beautiful patio. Location was perfect to access Elephant Rocks, Johnson Shut-ins, and Taum Sauk Mountain parks. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber S. £146 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Ironton-Hotels-Mountain-View-At-Pickle-Perk.h105789927.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/de7e2348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/0c3489d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/d1a4afba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/eab48480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided [](https://www.expedia.co.uk/Secluded-In-The-Woods.h89701234.Hotel-Information) Greenville 10/10 Exceptional (6 reviews) "Cute, cozy, private getaway that you won't want to leave!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jade G. £192 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Secluded-In-The-Woods.h89701234.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/f432dafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6d0c8b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/0e13dd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/564d6e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space [](https://www.expedia.co.uk/Sikeston-Hotels-Serenity-South-Gardens.h38940154.Hotel-Information) Cape Girardeau 10/10 Exceptional (150 reviews) "Such a great place and location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy H. £184 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Sikeston-Hotels-Serenity-South-Gardens.h38940154.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/a08b65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w830h683x97y0-bd7b87e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w507h683x259y0-84bc4b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w695h683x165y0-d0f50453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "Little Brick House on Main (1865)” [](https://www.expedia.co.uk/Ste-Genevieve-Hotels-Little-Brick-House.h88996203.Hotel-Information) Ste. Genevieve 10/10 Exceptional (64 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lettitia B. £122 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Ste-Genevieve-Hotels-Little-Brick-House.h88996203.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=6058763&adults=2&location_highlights_explore=shopping&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Missouri Hotel Reviews ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Everything was wonderful. It was clean, staff was so friendly and welcoming. Breakfast was very well taken care of, including the night time social hour." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Accommodation " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/720261dc_y.jpg) ### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG 10/10 Excellent "Nice, clean hotel. Would stay again." 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