
Find Cheap Hotels in Southeast Missouri, MO
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Check availability on Southeast Missouri Cheap Hotels
Our top choices for Southeast Missouri cheap hotels

1. Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff
2. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
3. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
4. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff
5. The Riverview
The Riverview
6. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
7. Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter
8. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
9. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
10. Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
12. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
13. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
14. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
15. Shepherd Mountain Inn
Shepherd Mountain Inn
16. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
17. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG
18. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
19. Fort Davidson Hotel
Fort Davidson Hotel
20. Hampton Inn & Suites By Hilton Festus
Hampton Inn & Suites By Hilton FestusFind out more about Southeast Missouri
How to get cheap hotels in Southeast Missouri?
✅ The length of stay in Southeast Missouri often varies depending on the nature of the trip, but many travellers opt to stay for several days or up to a week to take in Southeast Missouri's notable landmarks and points of interest.
✅ If you're looking for cheap hotels in Southeast Missouri in 2026, book your hotel well in advance. Reserving your stay at least a few weeks or months ahead of time can help you take advantage of amazing rates on cheap hotels in Southeast Missouri, and if your plans change you can find many options of hotels with free cancelation.
✅ To find affordable hotels in Southeast Missouri on Expedia, start by entering your travel dates and the number of individuals in your group. Once you've provided this information, you can refine your search results by filtering for budget hotels in Southeast Missouri.
✅ Use the filtering tools offered by Expedia to refine your search results by location, price limits, amenities such as breakfast included, and other factors that matter to you. This will help you quickly locate the ideal budget-friendly hotel that fits your specific requirements.
✅ If you're looking to save money on a cheap hotel in Southeast Missouri, the ideal time to go is usually during the off-season in Southeast Missouri. On Expedia, you can find hotels from £46*.
✅ Southeast Missouri offers numerous budget-friendly attractions and activities for travellers, such as art and exhibits at free museums and galleries or exploring Southeast Missouri on foot.
✅ One of the best ways to find cheap hotels in Southeast Missouri is to search Expedia for properties that provide family-friendly accommodations and features such as activities and complimentary meals, and then sort these by price.
*Prices and availability are subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Super 8 by Wyndham Sikeston/Miner Area
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- Rustic River Cabin Getaway
- B&B in Black
- Bloomsdale Suite at Baetje Farms
- Adults Only Resorts & in Cape Girardeau
- “Brickyard”
- The Riverview
- Tru By Hilton Cape Girardeau
- Doe Run Hotels
- Current River Cottage
- Doniphan Hotels
- Ellington Hotels
- Hogan’s Hideout Bonnie Manor
- Crown Pointe Lodge
- High Hope Tree House #1 @Spring Lake Ranch
- ❤️ THE MAGIC TIPI RETREAT
- Farmington Hotels
- Fredericktown Hotels
- Postcard Cabins St Francois
- Glen Allen Hotels
- Hotels near Johnson's Shut-ins State Park
- Junction City Hotels
- Black River Motel and Restaurant
- Gay-Friendly Hotels in Lesterville
- Wilderness Lodge
- Lithium Hotels
- Middle Brook Hotels
- New Offenburg Hotels
- Urban Lofts
- Dancing Under Red Skies Tree House @Spring Lake
- Potosi Hotels
- Dexter Inn
- Drury Plaza Hotel Cape Girardeau Conference Center
- Fairfield Inn & Suites by Marriott Sikeston
- Hampton Inn Sikeston
- The cabin in Eden
- Towneplace Suites by Marriott Sikeston
- Travel Inn & Suites
- Sikeston Hotels
- Hotels with Connecting Rooms in Southeast Missouri
- Pet-Friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Hotels near Southeast Missouri State University
- Peaceful 4BR ranch w/ hot tub
- Silo Farm Haus
- 1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi
- Winona Hotels
- Flights to Bonne Terre
- Flights to Cape Girardeau
- Flights to Desloge
- Flights to Park Hills
- Flights to Wappapello
- Flights from Cape Girardeau Municipal
- Flights from Ste Genevieve
- Flights from Black
- Flights from Lesterville
- Flights from Dexter
- Flights from Viburnum
- Flights from Bonne Terre
- Flights from Arcadia
- Flights from London (LHR) to Cape Girardeau (CGI)


























































