Title: TOP Smoking Hotels in South Carolina Midlands, SC for 2026 | Expedia.co.uk [South Carolina Midlands Travel Guide](https://expedia.co.uk/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Holiday Rentals in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Holiday-Rentals.d6057938.Travel-Guide-HolidayRentals)[Flights to South Carolina Midlands](https://expedia.co.uk/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.co.uk/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Carolina-Midlands.d6057938.Car-Hire-Guide)[South Carolina Midlands Holidays](https://expedia.co.uk/South-Carolina-Midlands.d6057938.Holidays-City-Breaks) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Hotels with smoking rooms Tonight [2 Feb - 3 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Feb - 4 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-03&endDate=2026-02-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina Midlands hotels with designated smoking areas ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/5cc0357e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2a6d6c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/fcf4fdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Latta by IHG [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) Latta 9.4/10 Exceptional (549 reviews) "Front desk is amazing! Rooms are clean and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £100 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/26a37b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/aa45ff7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/7d3e14d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/21d6ef64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rock Hill [](https://www.expedia.co.uk/Rock-Hill-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rock-Hill.h26598714.Hotel-Information) Rock Hill 9.0/10 Wonderful (1,094 reviews) "Would stay here again, good location. Clean, good room with comfortable bed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) laura £68 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Rock-Hill-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rock-Hill.h26598714.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.co.uk/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) Florence 7.8/10 Good (1,005 reviews) "Front desk staff was great and very friendly! Made for a smooth check-in!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patric £73 includes taxes & fees 3 Feb - 4 Feb [](https://www.expedia.co.uk/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Two double beds non smoking | View from room](https://images.trvl-media.com/lodging/1000000/30000/20400/20339/f82209a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20400/20339/4971f784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20400/20339/00cfcb27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20400/20339/eb42984a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sumter [](https://www.expedia.co.uk/Sumter-Hotels-Hampton-Inn-Sumter.h20339.Hotel-Information) Sumter 8.6/10 Excellent (492 reviews) "Truly enjoy staying here, the staff is extremely friendly and understanding! It is very clean and comfortable! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stefanie £75 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Sumter-Hotels-Hampton-Inn-Sumter.h20339.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/0f2c01c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/7b635fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/502487e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Columbia/Harbison [](https://www.expedia.co.uk/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) Columbia 9.0/10 Wonderful (1,958 reviews) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana £73 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,003 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale £77 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/852cfc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,258 reviews) "I have to say it was all especially the staff very welcoming to us when we came when I came in room is very well clean. I will definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita £69 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/32b6a3bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/e94102a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/21565fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/a1a27db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lexington Expo Hotel by IHG [](https://www.expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia-Lexington.h1823665.Hotel-Information) Lexington 9.2/10 Wonderful (1,001 reviews) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Konrad £100 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia-Lexington.h1823665.Hotel-Information) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/1000000/860000/855800/855715/0c333f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/855800/855715/e0bef5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Laptop workspace, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/860000/855800/855715/d46882bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/860000/855800/855715/b6d5aa2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Aiken South [](https://www.expedia.co.uk/Aiken-Hotels-Americas-Best-Value-Inn-Aiken.h855715.Hotel-Information) Aiken 7.4/10 Good (308 reviews) "All equestrians and future visitors to Aiken should stay away from this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dennis £56 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Aiken-Hotels-Americas-Best-Value-Inn-Aiken.h855715.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/3ffa2f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 8.8/10 Excellent (695 reviews) "Nice roomy clean rooms, staff were great, indoor heated pool was nice accomadation for this time of year for the kids. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £85 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=6057938&adults=2&property_amenities_group_explore=designated_smoking_areas&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Midlands Hotel Reviews ![Baymont by Wyndham Columbia Fort Jackson](https://images.trvl-media.com/lodging/1000000/580000/574500/574461/c68af965_y.jpg) ### Baymont by Wyndham Columbia Fort Jackson 10/10 Excellent "Rooms were nice and the checking was fast and easy. " [](https://expedia.co.uk/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Fort-Jackson.h574461.Hotel-Information) ![Hyatt Place Columbia/Downtown/The Vista](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690567/c2bace01_y.jpg) ### Hyatt Place Columbia/Downtown/The Vista 10/10 Excellent "The staff was very friendly. Loved the bar and food. Great location for Gamecocks basketball games " [](https://expedia.co.uk/Columbia-Hotels-Hyatt-Place-ColumbiaDowntownThe-Vista.h8690567.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Spa Hotels in Blythewood ](https://www.expedia.co.uk/Blythewood-Hotels-Spa-Hotels.0-0-d180657-tSpaHotels.Travel-Guide-Filter-Hotels) - [Blythewood Hotels ](https://www.expedia.co.uk/Blythewood-Hotels.d180657.Travel-Guide-Hotels) - [Adults Only Resorts & in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Adults-Only-Resorts.0-0-d764-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Budget-Hotels.0-0-d764-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Gay-Friendly-Hotel.0-0-d764-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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