Title: South Carolina Lakeside Hotels, United States of America: South Carolina Hotel Guide | Expedia.co.uk [South Carolina Travel Guide](https://expedia.co.uk/South-Carolina.dx242)[South Carolina Hotels](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Holiday Rentals in South Carolina](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations)[South Carolina Flights](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Hire](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Car-Hire-Destinations)[South Carolina Holidays](https://expedia.co.uk/South-Carolina.d242.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Carolina Accommodation: Most Popular Cities to Stay ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/184000/184006-State-House.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Columbia [](https://expedia.co.uk/Columbia-Hotels-Lakeside-Hotel.0-0-d764-tlakesidehotel.Travel-Guide-Filter-Hotels) ![Greenville featuring a bridge, a city and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.co.uk/Greenville-Hotels-Lakeside-Hotel.0-0-d1388-tlakesidehotel.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina Lakeside Hotels Tonight [25 Jan - 26 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-25&endDate=2026-01-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Jan - 27 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-26&endDate=2026-01-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina hotels on the lake ![Exterior](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/3f86955d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/01db0d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/5c2ecfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/930bce4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax on the shore of Lake Hartwell in our Fair Play retreat [](https://www.expedia.co.uk/Anderson-Hotels-Charming-Secluded.h18765211.Hotel-Information) Fair Play 9.8/10 Exceptional (236 reviews) "The property was lovely and accurate to what the hosts described. We would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lawren C. [](https://www.expedia.co.uk/Anderson-Hotels-Charming-Secluded.h18765211.Hotel-Information) ![Smart TV, fireplace, DVD player, toys](https://images.trvl-media.com/lodging/19000000/18770000/18760800/18760760/568a27a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18770000/18760800/18760760/77429f2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18770000/18760800/18760760/c51e5ab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18770000/18760800/18760760/072dca79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks [](https://www.expedia.co.uk/Seneca-Hotels-Anchors-Down-Lakeside-Retreat-15-Min-To-Clemson-Dock.h18760760.Hotel-Information) Seneca 10/10 Exceptional (236 reviews) "Lovely property- we had a great visit! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda G. [](https://www.expedia.co.uk/Seneca-Hotels-Anchors-Down-Lakeside-Retreat-15-Min-To-Clemson-Dock.h18760760.Hotel-Information) ![Golf](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/63d829f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/0aec11f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn [](https://www.expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Clemson 9.6/10 Exceptional (965 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindi £121 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/42900/42875/74f13525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42875/b555e7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42900/42875/543a46ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Refrigerator & Microwave, Lake View | Living area | Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/1000000/50000/42900/42875/75fa3af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Columbia I-26/Harbison Blvd. [](https://www.expedia.co.uk/Columbia-Hotels-Hampton-Inn-Columbia-I-26Harbison-Blvd.h42875.Hotel-Information) St. Andrews 9.0/10 Wonderful (1,002 reviews) "The room was very clean, the continental breakfast was great. We only stayed one night but the staff was very nice and welcoming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yolanda £80 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Hampton-Inn-Columbia-I-26Harbison-Blvd.h42875.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6480000/6471600/6471565/fd13802f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6480000/6471600/6471565/aef3f74a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6480000/6471600/6471565/78f783c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6480000/6471600/6471565/7737c481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charleston Kiawah Island/Andell Inn [](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Kiawah-IslandAndell-Inn.h6471565.Hotel-Information) Kiawah Island 9.6/10 Exceptional (523 reviews) "Great hotel and close to everything" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £258 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Kiawah-IslandAndell-Inn.h6471565.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18770000/18767300/18767280/476dfa77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18770000/18767300/18767280/ed65a95d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18770000/18767300/18767280/61ea178b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/19000000/18770000/18767300/18767280/051b7909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scenic Carolina Waterfront Rentals - Arco [](https://www.expedia.co.uk/North-Charleston-Hotels-Scenic-Carolina-Waterfront-Rentals-Arco.h18767280.Hotel-Information) Charleston 9.4/10 Exceptional (84 reviews) "We really enjoyed the house. We will be back. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mauricio o. [](https://www.expedia.co.uk/North-Charleston-Hotels-Scenic-Carolina-Waterfront-Rentals-Arco.h18767280.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/6e2c44a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/5f39b433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/795b3938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/6959b215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Days-Inn-By-Wyndham-Columbia.h532027.Hotel-Information) St. Andrews 4.2/10 (1,003 reviews) "The sink clogged during the second day." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn £51 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Columbia-Hotels-Days-Inn-By-Wyndham-Columbia.h532027.Hotel-Information) ![Smart TV, DVD player, books, music library](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763932/6c349d16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, sun-loungers, beach towels](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763932/fe703693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763932/49a8d41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763932/f34b8d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EXCEPTIONAL Large and Private Villa in Palmetto Dunes Resort!! 5-Star Reviews!!! [](https://www.expedia.co.uk/Hilton-Head-Hotels-Exceptional-Palmetto-Dunes-Villa-5-Star-Reviews-UV-Light-System-Kills-Viruses.h18763932.Hotel-Information) Mid Island 10/10 Exceptional (273 reviews) "Everything was great. Convenient to beach, pool, restaurants, groceries, golf, practically everything you need or want. Very clean and well equipped.Would stay there again and recommend to friends " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike H. [](https://www.expedia.co.uk/Hilton-Head-Hotels-Exceptional-Palmetto-Dunes-Villa-5-Star-Reviews-UV-Light-System-Kills-Viruses.h18763932.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19170000/19165200/19165103/971fdafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player](https://images.trvl-media.com/lodging/20000000/19170000/19165200/19165103/62d09b84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/20000000/19170000/19165200/19165103/2138cd80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/20000000/19170000/19165200/19165103/20d8cf0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront 3 Bedroom, 2 Bath and Pet Friendly Near Chattooga River and Belle Farm [](https://www.expedia.co.uk/Long-Creek-Hotels-Lakefront-3-Bedroom.h19165103.Hotel-Information) Long Creek 9.8/10 Exceptional (49 reviews) "This was an amazing property and close to all of our weekend activities. Absolutely felt like home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley M. £364 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Long-Creek-Hotels-Lakefront-3-Bedroom.h19165103.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/070e1043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/5b49de0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/9e846421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (642 reviews) "A good option if traveling with pets. The hotel is clean and well maintained but dated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £53 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-08&endDate=2026-02-09®ionId=242&adults=2&location_highlights_explore=on_lake&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Lakeside-Hotel.0-0-d242-tlakesidehotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Lakeside-Hotel.0-0-d242-tlakesidehotel.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![Holiday Inn Express Hilton Head Island by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3_y.jpg) ### Holiday Inn Express Hilton Head Island by IHG 10/10 Excellent "Good deal and clean." [](https://expedia.co.uk/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/bde1e3a3_y.jpg) ### La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy 10/10 Excellent "Nice room, clean and staff was friendly " [](https://expedia.co.uk/Myrtle-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Myrtle-Beach-N-Kings-Hwy.h6849.Hotel-Information) ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Staff were friendly " [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Dunes Village Resort](https://images.trvl-media.com/lodging/1000000/990000/983000/982925/a147d3c1_y.jpg) ### Dunes Village Resort 10/10 Excellent "Nice clean rooms" [](https://expedia.co.uk/Myrtle-Beach-Hotels-Dunes-Village-Resort.h982925.Hotel-Information) ![Sonesta Resort Hilton Head Island](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/220ad345_y.jpg) ### Sonesta Resort Hilton Head Island 10/10 Excellent "Breakfast was great ." [](https://expedia.co.uk/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) ![The Ryder Hotel](https://images.trvl-media.com/lodging/1000000/10000/4600/4544/722c7929_y.jpg) ### The Ryder Hotel 10/10 Excellent "Great location, comfortable beds." [](https://expedia.co.uk/Charleston-Hotels-The-Ryder-Hotel.h4544.Hotel-Information) ![HarbourView Inn](https://images.trvl-media.com/lodging/1000000/110000/106200/106135/1cee711c_y.jpg) ### HarbourView Inn 10/10 Excellent "Everything about the hotel was a great experience for us. The staff was very friendly and helpful. We especially loved the complimentary experiences. That was a very nice touch. Would definitely go back " [](https://expedia.co.uk/Charleston-Hotels-HarbourView-Inn.h106135.Hotel-Information) ![Planters Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/c138e1de_y.jpg) ### Planters Inn 10/10 Excellent "Great Room and Staff" [](https://expedia.co.uk/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ![Hilton Grand Vacations Club Ocean Enclave Myrtle Beach](https://images.trvl-media.com/lodging/34000000/33220000/33213200/33213151/d233caaf_y.jpg) ### Hilton Grand Vacations Club Ocean Enclave Myrtle Beach 10/10 Excellent "Wonderful stay" [](https://expedia.co.uk/Myrtle-Beach-Hotels-Ocean-Enclave-By-Hilton-Grand-Vacations.h33213151.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Arsenal Hill Hotels ](https://www.expedia.co.uk/Arsenal-Hill-Columbia-Hotels.0-n6346756-0.Travel-Guide-Filter-Hotels) - 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