Title: TOP Hotels with Air Conditioning in Santee, SC for 2025 | Expedia.co.uk [Hotels in Santee](https://expedia.co.uk/Santee-Hotels.d9953.Travel-Guide-Hotels)[Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d9953.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d9953.Car-Hire-Guide)[Santee Holidays](https://expedia.co.uk/Santee.d9953.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/271db9a9db85f6f3488271b71d2f238f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels with Air Conditioning in Santee ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santee Hotels with Air Conditioning Tonight [18 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-10-18&endDate=2025-10-19&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Oct - 20 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-10-19&endDate=2025-10-20&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [31 Oct - 2 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santee Hotels with Air Conditioning ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/828f10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee Santee 9.2/10 Wonderful (566) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon £81 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1370) "Good overall stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Junming £62 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1006) "Great stay for a quick weekend getaway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle £103 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/e757bdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 Santee 9.6/10 Exceptional (1004) "Rooms were nice size and very clean. Staff was so nice and helped us find some local spots to eat. Highly recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £99 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/e27bc6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/442e4efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG Santee 8.2/10 Very good (955) "Great hotel w" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth £98 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/dc9ab090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn Santee 8.8/10 Excellent (1007) "We really enjoyed our stay and will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £98 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/6e319d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/ddfa8a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee Santee 8.0/10 Very good (1003) "The room and Hotel was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory £88 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Smart TV, offices](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/10896652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/79beb629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/431d124d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! Santee 10/10 Exceptional (36) "Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lauren B. £249 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/756c72ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee Santee 7.0/10 Good (663) "Good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £50 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee Santee 6.8/10 (435) "The nicest bathroom on our 12 day trip" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rhonda £62 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=9953&adults=2&amenities=AIR_CONDITIONING&sort=RECOMMENDED&openPlayBack=true) ## Top Santee Hotel Reviews ![Holiday Inn Santee by IHG](//images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 10/10 Excellent "Great hotel w" [](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Best Western Plus Santee Inn](//images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "Good" [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Travelodge by Wyndham Santee](//images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 10/10 Excellent "The counter tops and appliances needed cleaning, they were greasy. Otherwise the room was okay." [](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ## Frequently asked questions ### What are the best hotels with air conditioning in Santee? > Santee offers multiple hotels with air conditioning that have a total average guest review rating of 8.4. [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) is a highly rated option. This 2.5-stars property also comes with a firepit and a swimming pool. Another guest favourite that provides air-conditioned comfort is [Hampton Inn Santee-I-95](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information). A terrace and a swimming pool are among the amenities at this 2.5-stars escape. ### How many hotels with air conditioning are there in Santee? > Santee has 10 hotels with air conditioning. To help you locate a place that's perfect, use our handy filter tool to search for other amenities or perks you need. ### What are the best cheap hotels with air conditioning in Santee? > Hotels with air conditioning start from £50 per night, so your Santee getaway doesn't have to take a bite out of your budget! [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) is a pocket-friendly option that offers loads of amenities, including a firepit and a barbecue grill. [Hampton Inn Santee-I-95](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) is another one of our popular cheap hotels offering AC. Amenities here include a terrace and a swimming pool. If you're in search of something free to visit in Santee, [Santee Outlets](https://www.expedia.co.uk/Santee-Outlets-Santee.d6140634.Attraction) is worth adding to your itinerary. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the top motels with air conditioning in Santee? > Located around 1 mi southeast of the centre of Santee, [Super 8 by Wyndham Santee](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) is a top wallet-friendly motel with air conditioning. Also offering pool sun loungers and front desk services, this is a superb place to spend a getaway with your family or friends.With loads of cultural, retail and dining opportunities to squeeze into your Santee itinerary, it can be hard to know where to start. [Santee State Park](https://www.expedia.co.uk/Santee-State-Park-Santee.d6140632.Vacation-Attraction) and [Santee Cooper Country Club](https://www.expedia.co.uk/Santee-Cooper-Country-Club-Santee.d553248621532654899.Vacation-Attraction) are great places to get going on your sightseeing adventures. ### Are there any family-friendly hotels with air conditioning in Santee? > Settle in at [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information), a 2.5-stars option just a quick drive from downtown. Amenities here include complimentary breakfast, a firepit and in-room AC. Another family-friendly hotel with air conditioning is [Comfort Inn & Suites Santee](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information). Complimentary breakfast and WiFi help make this 2.5-stars escape a hit with guests. After checking in and chilling in your cosy digs, it's time to hit the road and discover the local sights. [Santee State Park](https://www.expedia.co.uk/Santee-State-Park-Santee.d6140632.Attraction) and [Santee Cooper Country Club](https://www.expedia.co.uk/Santee-Cooper-Country-Club-Santee.d553248621532654899.Attraction) are popular family-friendly attractions in Santee. ### Why book your hotel with air conditioning in Santee with Expedia? > Expedia has the best rates around for hotels with air conditioning in Santee. If you have a certain budget, select how much you're happy to spend and the star rating of your hotel. Then use our handy filters to search for air-conditioned retreats with amenities like a hot tub or free WiFi. We'll help you find the perfect place whatever your style of travel or plans. ### How can I find cheap hotels with air conditioning in Santee? > With Expedia's useful filter tool, scoring cheap hotels with air conditioning in Santee is easy. To discover accommodation with AC that are easy on your bank balance, narrow your search by budget and star rating. ### What is there to do in Santee near my hotel with air conditioning? > Once you've unpacked your suitcases, set out and explore the wonderful things Santee has to offer. 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[Hotels with Early Check-in in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Early-Check-In.0-0-d242-thotelwithearlycheckin.Hotel-Filter-Destinations) - [Hotels with Entertainment in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Entertainment.0-0-d242-thotelwithentertainment.Hotel-Filter-Destinations) - [Hotels with Indoor Pools in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotels-With-Indoor-Pools.0-0-d242-tHotelswithIndoorPools.Hotel-Filter-Destinations) - [Hotels with smoking rooms in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotels-With-Smoking-Rooms.0-0-d242-tHotelswithsmokingrooms.Hotel-Filter-Destinations) - [Hotels with Wifi in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotels-With-WiFi.0-0-d242-tHotelswithWiFi.Hotel-Filter-Destinations) - [Winery Hotels in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Winery-Hotels.0-0-d242-tWineryHotels.Hotel-Filter-Destinations) - 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