Save up to 17% by booking Flight + Hotel.
Search 590,000 properties and 550 airlines worldwide.
It's easy to book and save with flight and accommodation deals via Expedia. When you combine your hotel and flight purchases together into one simple package, you save money. Buy a little extra something in Santee thanks to the extra cash.
By securing a deal, you will save as much as 17%.
Our extensive database not only recommends 400 partner airlines and 321,000 worldwide hotels, but also features great discounts too.
There's no better time to start planning your getaway, with some of the best prices and packages at Expedia.
You may cancel or change almost any reservation and never pay a fee to us.
From Santee, it is roughly 50 miles northwest to Columbia and 60 miles southeast to Charleston.
The area around this destination features a number of wonderful natural areas. Two attractions nearby to Santee are Congaree National Park (30 miles away) and Colleton State Park (30 miles away).
One way to treat yourself in Santee is to open up your wallet at Santee Outlets.
Many people recommend stopping at Santee Cooper Country Club and Santee National Golf Club.
Vance and Elloree are two more places worth visiting while you're in the area. They're 5 miles and 6 miles away, respectively.
When you are ready to venture further afield, pay a visit to a regional hub. Sumter sits 30 miles away and serves up a varied list of attractions, such as Sumpter Gallery of Art, Crystal Lakes Golf Course and Dillion Park. Swan Lake Iris Gardens and Sumter Mall are also great if you're still looking for more.
There are some great calorie-burning outdoor activities in this region for when you want to get up and get active. Get your pulse up with a bit of hiking or zip-lining.
This area provides vacationers with plenty of relaxing pursuits in the great outdoors, such as cycling and picnicking.
Make your way to the water and make a splash with some swimming and rafting, a couple of the popular ways to get all wet here.
When the weather is fine, why not explore the region's gardens?
Time will seem to almost stand still when you wander through the historic mansions of South Carolina Midlands.
In order to truly appreciate the heart and soul of South Carolina Midlands, you're going to need to acquaint yourself with its particular scents and flavors.
Look around for oysters and fish, two renowned local ingredients.
Being here during the 4th of July will give you a good look at Independence Day.
When your departure time is nearing, know that Charleston International Airport is about 50 miles to the southeast.
You may not find an extensive range of hotel deals in Santee, so it would be wise to investigate the current listings and deals on Expedia's hotels page.
Situated in Santee, this hotel is within a 15-minute walk of Santee Cooper Country Club and Santee Outlets. Lake Marion is 2.9 mi (4.6 km) away.
Located in the heart of Santee, this hotel is within 1 mile (2 km) of Santee Cooper Country Club and Santee Outlets. Lake Marion and Santee State Park are also within 6 miles (10 km).
Located in the heart of Santee, this hotel is 0.8 mi (1.3 km) from Santee Outlets and 2.4 mi (3.9 km) from Lake Marion. Santee State Park is 3.4 mi (5.4 km) away.
Situated in a rural location, this hotel is 0.9 mi (1.5 km) from Santee Outlets and within 6 miles (10 km) of Lake Marion and Santee State Park. Foxboro Golf Club and Wyboo Golf Club are also within 25 miles (40 km).
Located in the heart of Santee, this motel is 0.7 mi (1.2 km) from Santee Outlets and 2.5 mi (4 km) from Lake Marion. Santee State Park and Foxboro Golf Club are also within 20 mi (32 km).
Situated in a rural location, this hotel is within 1 mile (2 km) of Santee Cooper Country Club and Santee Outlets. Lake Marion and Santee State Park are also within 6 miles (10 km).
Located in the heart of Santee, this hotel is 0.7 mi (1.1 km) from Santee Outlets and within 6 miles (10 km) of Lake Marion and Santee State Park. Foxboro Golf Club and Wyboo Golf Club are also within 25 miles (40 km).
Situated in St. George, this motel is within 12 miles (20 km) of Jennie J McMahan Library, St. George United Methodist Church and St. George Country Club. Santee Outlets and Lake Marion are also within 20 miles (32 km).