Title: Cheap Car Hire in Santee, USA - Expedia.co.uk [Santee Travel Guide](https://expedia.co.uk/Santee.dx9953)[Hotels in Santee](https://expedia.co.uk/Santee-Hotels.d9953.Travel-Guide-Hotels)[Flights to Santee](https://expedia.co.uk/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Holidays](https://expedia.co.uk/Santee.d9953.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/9953/712fb946-715a-4a74-8bf7-2c2bbd891023.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Santee, USA ## Search and Compare from Car Companies in Santee ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Santee \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Santee, South Carolina, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santee,%20South%20Carolina,%20United%20States%20of%20America&dpln=9953&date1=17/02/2026&date2=19/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Santee, South Carolina, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santee,%20South%20Carolina,%20United%20States%20of%20America&dpln=9953&date1=17/02/2026&date2=19/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Santee, South Carolina, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santee,%20South%20Carolina,%20United%20States%20of%20America&dpln=9953&date1=17/02/2026&date2=19/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Santee, South Carolina, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santee,%20South%20Carolina,%20United%20States%20of%20America&dpln=9953&date1=17/02/2026&date2=19/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Santee [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santee,%20South%20Carolina,%20United%20States%20of%20America&dpln=9953&date1=17/02/2026&date2=19/02/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day in Santee? ### What happens if I need to cancel my Santee car reservation? ### What types of cars can I rent in Santee? ### Where can I go on a road trip from Santee? > - You'll find Bank of America Stadium and lots more intriguing attractions in Charlotte. From Santee, it's 120 miles away. > - Your next stop? It has to be Columbia, which is around 50 miles away. University of South Carolina is one local hot spot you shouldn't miss. > - Make your way to Grandfather Mountain to reconnect with nature. Take a picnic to enjoy or just chill out in the fresh air. From Santee, it's approximately 200 miles away. ### How do I find the best car hire deals in Santee with Expedia? ### How old do you have to be to hire a car in Santee? ### What do you need to hire a car in Santee? ### What is the cheapest car hire in Santee? ### Can I hire a car for a month or longer in Santee? ### Where can I find a Santee hire car if I am younger than 25? ### Can I drive in Santee with my current driver's license? > - Age restrictions: You must be at least 25 in many states in order to hire a car, although in some places, the minimum age is 21 years. We recommend checking local regulations, as well as with the company you're hiring from before you travel to understand additional terms and conditions. > - Driving limitations: Read the fine print before you slide behind the wheel so you can avoid unnecessary fees. When hiring a car in the U.S, you usually can't cross country borders into Mexico or Canada, drive on ferries or traverse certain types of rugged terrain with a hire car. Please read the regulations before you book! ### Why should I rent a Santee car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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