Title: Hotels in Santee, SC - Best Santee Hotels from £45 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d9953.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d9953.Car-Hire-Guide)[Santee Holidays](https://expedia.co.uk/Santee.d9953.Holidays-City-Breaks) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santee Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-02-17&d1=2026-02-17&endDate=2026-02-19&d2=2026-02-19&amenities=PETS) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-02-17&d1=2026-02-17&endDate=2026-02-19&d2=2026-02-19&amenities=POOL) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-02-17&d1=2026-02-17&endDate=2026-02-19&d2=2026-02-19&lodging=CABIN) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-02-17&d1=2026-02-17&endDate=2026-02-19&d2=2026-02-19&lodging=COTTAGE) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-02-17&d1=2026-02-17&endDate=2026-02-19&d2=2026-02-19&travelerType=family_friendly) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-02-17&d1=2026-02-17&endDate=2026-02-19&d2=2026-02-19&lodging=CONDO) ## Check prices for these dates Tonight [3 Feb - 4 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-02-03&endDate=2026-02-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Feb - 5 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santee hotels ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,005 reviews) "Our room was super clean, breakfast was good. And the hotel was nice and quiet." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) john £98 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5ef3d5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (998 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie £96 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,000 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia £100 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,418 reviews) "Always a great stay. Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela £61 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.0/10 Good (694 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B £50 includes taxes & fees 24 Feb - 25 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,000 reviews) "Nice rooms and very good breakfast items." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £96 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (711 reviews) "Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £88 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,003 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale £79 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/dc3438b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (441 reviews) "The staff was very friendly and helpful. Room was clean and beds were so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy £61 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/070e1043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/5b49de0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (642 reviews) "A good option if traveling with pets. The hotel is clean and well maintained but dated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £53 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/0af71c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/51caeaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) Santee 6.4/10 (310 reviews) "Last minute arrangements stay was quiet and peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iasia £52 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/e77a8624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/50891687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (471 reviews) "Clean room but needs an exhaust fan in the bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leesa £48 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/daa776a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/2def81ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 [](https://www.expedia.co.uk/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) Santee 6.4/10 (549 reviews) "The grounds and property were clean and you could tell they take pride in what they're offering." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £65 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/27faffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e4316a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/9246a04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning [](https://www.expedia.co.uk/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) Manning 8.6/10 Excellent (1,002 reviews) "The room was very clean, the staff were very nice and the breakfast was ok. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha £72 includes taxes & fees 5 Feb - 6 Feb [](https://www.expedia.co.uk/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/27b2c420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11ccce69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (652 reviews) "Breakfast was an overstatement!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicki £61 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/d4b79aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) Orangeburg 8.2/10 Very good (1,000 reviews) "Enjoyed our stay " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Marie £58 includes taxes & fees 5 Feb - 6 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Deluxe Room, 1 King Bed, Non Smoking | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/120000/119200/119159/62fd9b11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/120000/119200/119159/2643428b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119200/119159/a9426d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/120000/119200/119159/e00356a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Manning [](https://www.expedia.co.uk/Sumter-Hotels-Baymont-By-Wyndham-Manning.h119159.Hotel-Information) Manning 6.8/10 (1,000 reviews) "Clean. Good value. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom £65 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Sumter-Hotels-Baymont-By-Wyndham-Manning.h119159.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a9d1fec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/71b46ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a0deabe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (718 reviews) "Overall a great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy £68 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/2e89db8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/ee5c02dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/37c1c14e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) Orangeburg 8.6/10 Excellent (801 reviews) "Accommodations were great. The staff is very courteous. Overall I enjoyed my stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Calvin £93 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/3ffa2f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 8.8/10 Excellent (695 reviews) "Nice roomy clean rooms, staff were great, indoor heated pool was nice accomadation for this time of year for the kids. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £85 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=9953&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels) ## Stay near popular Santee attractions ### Santee State Park 4.0/5 (112 reviews) Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6140632) ### Santee Cooper Country Club 3.9/5 (47 reviews) This George Cobb-designed course winds through majestic pines with strategic doglegs and panoramic Lake Marion views. Enjoy the signature closing hole and well-maintained fairways perfect for golfers of all skill levels. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654899) ### Santee National Golf Club 3.8/5 (43 reviews) This championship course blends Lowcountry charm with highland terrain, featuring moss-draped oaks and pristine bunkers. Enjoy diverse play with wide-open front nine and wooded back nine challenges. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654897) ## Learn more about Santee Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites. [See all hotels in Santee](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19&adults=2®ionId=9953) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=899&h=634&p=1&q=high) ## Top Santee Hotel Reviews ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Everything was great " [](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 10/10 Excellent "Clean and friendly " [](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "Friendly staff, updated hotel, safe area. Clean and modern rooms." [](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "Some recent updates are much appreciated. Staff is always very nice. The grounds and the room are very clean." [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Wyndham Vacation Resorts Lake Marion](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8_y.jpg) ### Wyndham Vacation Resorts Lake Marion 10/10 Excellent "The room was spacious and very clean. The front desk person was friendly and they did try to sell my fiance some things, but he wasn't interested. Once we kindly said no they understood and wasn't being pushy which we greatly appreciated. My family and I will stay here each time. My fiance and I dropped my niece off to college which is about 30 min away. She was able to have her own room and bathroom in addition to us. It was very safe and comfortable around the resort." [](https://expedia.co.uk/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 10/10 Excellent "Staff in the restaurant Dinner shift were excellent. " [](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Charming 2 Bedroom Waterfront Lake Marion Condo](https://images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/c68f4c0f_y.jpg) ### Charming 2 Bedroom Waterfront Lake Marion Condo 10/10 Excellent "The host was attentive and responsive, even inviting us to check in earlier. The home was lovely, well-cared for and thoughtfully appointed. The small touches, such as a basket of coffee and filters along with some snacks allowed us to have coffee the next morning despite getting into town when the stores were closed. We will absolutely return to this property and feel comfortable recommending it others. " [](https://expedia.co.uk/Santee-Hotels-Charming-2-Bedroom-Waterfront-Lake-Marion-Condo.h112149977.Hotel-Information) ## More cheap stays in Santee ![Baymont by Wyndham Orangeburg North](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Orangeburg North 3583 Saint Matthews Rd Orangeburg SC £45 11 Feb - 12 Feb includes taxes & fees 5.8/10 (1,001 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Super 8 by Wyndham, Orangeburg](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham, Orangeburg 3608 Saint Matthews Rd Orangeburg SC £47 1 Mar - 2 Mar includes taxes & fees 6.8/10 (913 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC £61 8 Feb - 9 Feb includes taxes & fees 7.8/10 Good! (1,419 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn by Marriott Orangeburg 663 Citadel Road Orangeburg SC £68 15 Feb - 16 Feb includes taxes & fees 8.2/10 Very Good! (714 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC £88 23 Feb - 24 Feb includes taxes & fees 9.2/10 Wonderful! (707 reviews) [](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Orangeburg 739 Citadel Road Orangeburg SC £93 5 Mar - 6 Mar includes taxes & fees 9/10 Wonderful! (1,004 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ## Find out more about Santee ### Top reasons to visit Santee - **Outdoor Activities:** Santee is a haven for outdoor enthusiasts, offering stunning scenery in national and state parks, ideal for hiking and picnicking. - **Golf Courses:** Enjoy a round of golf at local courses, surrounded by beautiful landscapes and a relaxed atmosphere. - **Relaxing Lakes:** Nearby lakes and sandy beaches provide perfect spots for leisure and romantic getaways. - **Southern Hospitality:** Experience the warm, welcoming atmosphere and friendly locals that characterise Santee. - **Varied Accommodation:** Choose from a range of hotels and motels, catering to different traveller needs and preferences. ### Find great hotels in Santee Explore a variety of hotel accommodation options in Santee, South Carolina, ideal for every traveller. From welcoming motels to well-appointed hotels, you'll find the perfect fit for your needs, whether you're seeking pet-friendly amenities, a business-focused environment, or an LGBTQIA-friendly atmosphere. Discover the best Santee hotels that offer comfort and convenience for your memorable stay in this charming town. - **[Best Western Plus Santee Inn: ](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)** Nestled in the heart of Santee, the Best Western Plus Santee Inn caters to business travellers seeking a practical yet comfortable stay. This hotel offers a range of facilities, including a fully-equipped Business Centre and versatile Meeting Rooms ideal for conferences. Notably, it welcomes pets, ensuring your furry companions can accompany you on your travels. With amenities such as a dedicated Dog Exercise Area and a pet-friendly policy for dogs and cats, this hotel strikes a balance between professional needs and family-friendly accommodation. - **[Hampton Inn Santee-I-95: ](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)** The Hampton Inn Santee-I-95 prides itself on being an inclusive retreat for all guests, including those with pets. This hotel boasts a warm and welcoming atmosphere, with a commitment to LGBTQIA+ travellers. It features a variety of amenities designed for comfort and convenience, including complimentary breakfast and a fitness centre. The pet policy allows for dogs and cats, with a variable fee, making it an ideal stop for pet owners looking for a friendly environment. Enjoy a pleasant stay that feels like home while exploring Santee. - **[Travelodge by Wyndham Santee: ](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)** The Travelodge by Wyndham Santee is a straightforward and budget-friendly option for those travelling with pets. Situated conveniently in Santee, this hotel provides essential amenities for a comfortable stay, including free Wi-Fi and parking. The pet-friendly policy allows you to bring your dogs along, ensuring a hassle-free experience for pet owners. With its emphasis on affordability and convenience, the Travelodge is perfect for families and travellers seeking a relaxed atmosphere without compromising on comfort. ### Where to stay near Santee Santee, South Carolina, offers a delightful blend of outdoor activities and Southern hospitality. Explore the scenic lakes and sandy beaches nearby, perfect for a romantic getaway or family excursion. Discover the friendly atmosphere and budget-friendly attractions that define this charming city. From its picturesque surroundings to local excursions, Santee promises a memorable vacation experience for every traveller. - **[Summerton: ](https://www.expedia.co.uk/Summerton-Hotels.d163488.Travel-Guide-Hotels)** Situated 6.8km from Santee, Summerton is a charming city that beckons visitors with its picturesque outdoor scenery and romantic ambiance. Though traveller arrivals fluctuate throughout the year, the peak seasons in March to April and July draw those eager to explore its recreational areas and well-maintained golf courses. The local attractions, including serene lakes and the nearby national state park, offer ample opportunities for relaxation and adventure, making Summerton an appealing destination for nature lovers and couples alike. - **[Vance: ](https://www.expedia.co.uk/Vance-Hotels.d3000456153.Travel-Guide-Hotels)** A mere 3.1km from Santee, Vance is a delightful city known for its highly seasonal influx of visitors. The bustling periods in March to April and July invite outdoor enthusiasts to experience the stunning landscapes and recreational opportunities available. With a focus on golfing and exploration, Vance’s proximity to beautiful lakes and national parks, including scenic islands, makes it a perfect spot for those seeking a romantic getaway or an invigorating outdoor experience. Expect a warm welcome and an abundance of activities during your visit! - **[Elloree: ](https://www.expedia.co.uk/Elloree-Hotels.d3000455923.Travel-Guide-Hotels)** Located 3.7km from Santee, Elloree is a quaint city that offers a blend of outdoor beauty and romantic settings. Although visitor numbers are fairly steady throughout the year, peak seasons in March, July, and September provide an ideal backdrop for travellers seeking adventure. Explore the local recreational areas, golf courses, and the captivating natural surroundings, including lakes and national parks. Whether you’re planning a peaceful retreat or an active holiday, Elloree promises an unforgettable experience in the heart of South Carolina. ### Things to do in and around Santee Santee, South Carolina, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy a range of activities including exploring recreational areas and playing a round of golf at the local golf courses. The charming scenery provides a perfect backdrop for relaxation and adventure, making Santee a delightful spot for a vacation. **Shopping** In Santee, visit the Santee Outlets for a variety of shops in a lively atmosphere. If you're up for a drive, check out Pocalla Crossing Shopping Center, 16.8km away, for more shopping options, or Bee City, located 18.6km from Santee, for unique gifts. **Recreation** Enjoy a round of golf at Santee Cooper Country Club, where you can relish the outdoors amidst lush greens. For a tranquil escape, visit Santee National Wildlife Refuge, offering serene nature trails and wildlife observation. Alternatively, unwind at Patriots Sports Plex, featuring various recreational activities for relaxation. **Adventure** Santee State Park offers stunning views and a wealth of outdoor activities, including hiking trails along Lake Marion, fishing, and birdwatching. For a thrilling time, venture to the Santee National Wildlife Refuge, where you can explore diverse wildlife and scenic landscapes perfect for photography and nature walks. **Nightlife** Santee boasts a laid-back nightlife with charming venues like the Lake Marion Golf Club, where you can enjoy a relaxed evening with friends over drinks. The local bars often feature live music, creating a vibrant atmosphere perfect for unwinding after a day of exploring. ### Booking tips and Expedia advantages for Santee When visiting Santee, South Carolina, there are several ways to save money. Enjoy free activities like exploring Taw Caw Creek and take advantage of the free entry to public areas. For transport, consider using a bike or an affordable bus service. The cheapest months to visit are December to February, with Mondays often offering the best hotel rates. Use Expedia to compare prices, find great deals, and book packages that combine flights, hotels, and activities for additional savings. Look for eco-certified hotels to save while supporting sustainability. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to set your budget, choose your desired location, and much more. You can organise your results to display prices from lowest to highest, allowing you to find the most affordable hotels first. Additionally, you have the option to refine your search by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking. - **Consider bundling your trip:** You can potentially save money by combining your hotel reservation in Santee with your flights and activities through an Expedia package. ### Find the best attractions in and around Santee Santee, South Carolina, is perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitors can enjoy the stunning scenery at nearby national and state parks, as well as relaxing at local lakes and islands. With a variety of attractions catering to outdoor activities, beach relaxation, and cultural experiences, Santee promises a delightful vacation for all types of travellers. - **Santee State Park:** Immerse yourself in the natural beauty of Santee State Park, where outdoor enthusiasts can enjoy hiking, fishing, and camping amidst scenic landscapes and tranquil vibes. The park offers a perfect escape for adventure seekers and nature lovers alike. - **Santee Town Hall:** Visit Santee Town Hall to appreciate its architectural charm and learn about the local governance. This hub of community activity provides insight into the town’s business and civic life, making it a unique spot for understanding Santee’s culture. - **Taw Caw Creek:** Located 5.6km from Santee, Taw Caw Creek is a picturesque lake, ideal for romantic outings and serene picnics. Enjoy the stunning views, sandy beaches, and outdoor activities that make it a perfect retreat for couples and families. ### Best time to go to Santee The best time to visit Santee is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 47.3°F (8.5°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 51.4°F (10.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 56.8°F (13.8°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | April | 64.4°F (18.0°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | May | 72.0°F (22.2°C) | Light Rain | Mostly Sunny | Average | Average | | June | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 79.9°F (26.6°C) | Light Rain | Mostly Sunny | Average | Average | | September | 75.4°F (24.1°C) | Light Rain | Mostly Sunny | Average | Average | | October | 66.4°F (19.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 56.1°F (13.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | December | 51.3°F (10.7°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Santee When planning your visit to Santee, South Carolina, you can fly into two major airports. Charleston International Airport ([CHS](https://www.expedia.co.uk/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is situated 30.4km away, with excellent hotel options like [The Charleston Place](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information), [Hotel Bennett](https://www.expedia.co.uk/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), and [The Dewberry Charleston](https://www.expedia.co.uk/Charleston-Hotels-The-Dewberry-Charleston.h12880056.Hotel-Information), all offering transportation services to the airport. Alternatively, Columbia Metropolitan Airport ([CAE](https://www.expedia.co.uk/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels)) is also 30.4km from Santee, featuring hotels such as [Graduate by Hilton Columbia SC](https://www.expedia.co.uk/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information), [Doubletree by Hilton Columbia](https://www.expedia.co.uk/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information), and [Marriott Columbia](https://www.expedia.co.uk/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information), all conveniently located for easy access to the airport. Both airports provide a range of services to ensure a smooth start to your holiday. ## Frequently asked questions ### What is the best area to stay in Santee? > This area is the main visitor hub in Santee. You'll find a concentration of accommodation options, restaurants, and shops conveniently located near the interstate exits. It's a practical and straightforward layout, making it easy to navigate. > > > For travellers interested in outdoor activities and nature, this location is ideal. The Santee National Wildlife Refuge, a significant natural landmark, is easily accessible, offering opportunities for birdwatching, hiking, and exploring the local ecosystem. Many hotels in this area cater to guests looking for comfortable stays after a day of outdoor adventures. > > > Golf enthusiasts will also find this area particularly convenient. Several much-loved golf courses are situated within a short drive, making it simple to get to and from the greens. ### What are the best hotels in Santee that travellers recommend? > The 3-star [Holiday Inn Santee by IHG](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information), with an 8.2 rating, offers comfortable and quiet rooms, with guests often praising the friendly and helpful staff. For those interested in golf, the hotel has a golf course nearby and offers golf caddies, carts, and advance notice for golf games. There is also an indoor pool and room service available. > > > The Best Western Plus Santee Inn, rated 8.8, is known for its nice, clean rooms and comfortable beds. Guests frequently mention the delicious free breakfast and good amenities, including a private indoor hot tub and an outdoor pool. The front desk staff are also noted for being very helpful. Santee State Park is approximately 5.2 km away. > > > Another excellent choice is the Comfort Inn & Suites Santee, which has an 8.0 rating. This hotel provides spacious suites, connecting rooms, and free cribs for families. Guests particularly appreciate the hot and good free buffet breakfast. The rooms are consistently described as nice and clean, and the staff are friendly. Santee State Park is just 4.7 km from the hotel. > > > Finally, the Baymont by Wyndham Santee, with an 8.0 rating, offers nice, clean rooms with comfortable beds, and guests often highlight the great price. A free continental breakfast is provided, and the staff are consistently described as nice and amazing. Santee State Park is approximately 4.8 km away. ### What are the best family hotels in Santee? > The Fairfield Inn & Suites by Marriott Santee, with an outstanding 9.8 rating, is a superb choice for families. Guests consistently highlight the comfortable and clean rooms, the excellent and friendly staff, and the great complimentary breakfast. The hotel also offers a pool, sofa beds, and provides both cribs and highchairs for children, ensuring a comfortable stay for all family members. It is conveniently located just 5.3 km from Santee State Park. > > > Another highly recommended option is the Hampton Inn Santee-I-95, which boasts a 9.6 rating. This hotel is praised for its friendly and helpful staff, comfortable and clean rooms, and delicious complimentary breakfast. Amenities suitable for families include a pool, sofa beds, and free cribs and rollaway beds. It is also situated 5.3 km from Santee State Park. ### What hotels in Santee offer free breakfast? > The 9.8-rated Fairfield Inn & Suites by Marriott Santee provides a free buffet breakfast, and guests often mention the excellent and friendly staff, comfortable and clean rooms, and the great breakfast. Free self-parking and free WiFi are also available. > > > Hampton Inn Santee-I-95, with a 9.6 rating, offers a free breakfast that guests describe as delicious. The staff are frequently praised for being friendly and helpful, and the rooms are noted as comfortable and clean. This hotel also provides free WiFi and free self-parking. > > > Tru By Hilton Santee, rated 9.2, includes a free buffet breakfast. Guests appreciate the nice and clean rooms, as well as the friendly and helpful staff. Free self-parking and free WiFi are among its amenities. > > > The 8.8-rated Best Western Plus Santee Inn offers a complimentary breakfast, with guests specifically highlighting the free continental breakfast as delicious. The rooms are described as nice and clean, and the beds are comfortable. Free self-parking and free WiFi are also provided. > > > Baymont by Wyndham Santee, with an 8.0 rating, also includes a free continental breakfast. Guests frequently mention the nice and clean rooms and the amazing staff. Free self-parking and free WiFi are available. ### What are the top pet-friendly hotels in Santee? > The Fairfield Inn & Suites by Marriott Santee, with an excellent 9.8 rating, is highly praised by guests for its comfortable and clean rooms, great breakfast, and excellent staff. This hotel permits both dogs and cats and provides a dedicated dog exercise area, making it very convenient for pet owners. It is located just 5.3 km from Santee State Park. > > > The 3-star Holiday Inn Santee by IHG, rated 8.2, welcomes both dogs and cats. Guests frequently mention the clean and quiet rooms, friendly and helpful staff, and super comfortable beds. There is also a nice bar on site, and the hotel is 4.7 km from Santee State Park. > > > The Red Roof Inn Santee permits both dogs and cats and is known for its great price. It is conveniently located 4.6 km from Santee State Park. > > > The Best Western Plus Santee Inn, with an 8.8 rating, is another excellent choice for pet owners, permitting both dogs and cats and offering a dog exercise area. Guests appreciate the nice, clean rooms, comfortable beds, and the delicious free continental breakfast. The helpful front desk staff also receives positive mentions. It is 5.2 km from Santee State Park. > > > The Quality Inn & Suites permits both dogs and cats and provides a free full breakfast. Guests often praise its great location, nice rooms, and good amenities. It is situated 4.5 km from Santee State Park. ### What are the best budget hotels in Santee? > The Fairfield Inn & Suites by Marriott Santee, with an impressive 9.8 rating, offers guests a comfortable stay with excellent amenities. Guests frequently praise the friendly and helpful staff, the clean and comfortable rooms, and the great free buffet breakfast. It is conveniently located approximately 5.3 km from Santee State Park. > > > Another good option is the Baymont by Wyndham Santee, which has a rating of 8.0\. This hotel provides a complimentary continental breakfast, free WiFi, and free parking for cars, RVs, buses, and trucks. Its rooms are described as nice and clean, and the staff are often highlighted as amazing. Santee State Park is around 4.8 km away. ### What are the most romantic hotels in Santee for couples? > The Best Western Plus Santee Inn, with an 8.8 rating, offers premium rooms that guests describe as nice and clean. It provides a complimentary continental breakfast, and couples can enjoy the added luxury of a private indoor hot tub. The hotel is conveniently located just 0.1 km from Santee Cooper Country Club. > > > Another excellent option is the Waterfront Condo on Lake Marion, which boasts a superb 10.0 rating. This accommodation provides stunning water views and features a fully equipped kitchen, a deck or patio, and access to golf facilities both onsite and nearby. It is situated 1.5 km from Santee Cooper Country Club. ### What are the best hotels in Santee near Santee State Park? > The Fairfield Inn & Suites by Marriott Santee has an outstanding 9.8 rating and is located 5.3 km from Santee State Park. Guests frequently praise the excellent and friendly staff, comfortable and clean rooms, and the great free buffet breakfast. This hotel also offers a pool, sofa beds, and cribs, making it very suitable for families. > > > Another highly-rated option is the Hampton Inn Santee-I-95, with a 9.6 rating, also 5.3 km from Santee State Park. Travellers appreciate the friendly and helpful staff, comfortable and clean rooms, and delicious free breakfast. The hotel provides free WiFi, a pool, and free parking for RVs, buses, or trucks, along with complimentary cribs and rollaway beds. > > > The Tru By Hilton Santee, with a 9.2 rating and located 4.8 km from Santee State Park, is another strong contender. Guests praise the nice and clean rooms, friendly and helpful staff, and excellent free buffet breakfast. Free toiletries and self-parking are also provided. > > > The [Best Western Plus Santee Inn](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information), rated 8.8 and 5.2 km from Santee State Park, offers nice and clean rooms with super comfortable beds. Guests enjoy the free delicious continental breakfast and the helpful front desk. It also features a pool, connecting rooms, and free self-parking. > > > Finally, the 3-star [Holiday Inn Santee by IHG](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information), with an 8.2 rating and 4.7 km from Santee State Park, provides clean and quiet rooms with super comfortable beds. Guests highlight the friendly and helpful staff, and the nice bar. Free cribs, a pool, and free WiFi are available. ### When is the best time to go to Santee? > These seasons offer pleasant weather conditions, with comfortable temperatures and lower humidity, which is ideal for enjoying outdoor activities such as golfing, fishing, and exploring the natural beauty of Lake Marion and the surrounding areas. You'll find it's not too hot for a round of golf, nor too chilly for a boat trip. > > > For those planning a golf trip, these periods are particularly good as the courses are in excellent condition, and the weather allows for extended play without the intense heat of summer. You'll have a more enjoyable and relaxed time on the greens. > > > Families looking for a getaway will also appreciate these times of year. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santee hotel booking with Expedia? ### How much is the nightly rate at a Santee hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [3 Star Hotels in Davis Station ](https://www.expedia.co.uk/3Star-Davis-Station-Hotels.s30-0-d3000455905.Travel-Guide-Filter-Hotels) - [Alcolu Hotels ](https://www.expedia.co.uk/Alcolu-Hotels.d3000422483.Travel-Guide-Hotels) - [Marriott Hotels & Resorts in Bamberg ](https://www.expedia.co.uk/Bamberg-Hotels-Marriott-Hotels-Resorts.0-0-d55570--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Bowman Hotels ](https://www.expedia.co.uk/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Branchville Hotels ](https://www.expedia.co.uk/Branchville-Hotels.d3000455875.Travel-Guide-Hotels) - [Brookdale Hotels ](https://www.expedia.co.uk/Brookdale-Hotels.d553248634999003908.Travel-Guide-Hotels) - [Cameron Hotels ](https://www.expedia.co.uk/Cameron-Hotels.d553248634998916920.Travel-Guide-Hotels) - [Canadys Hotels ](https://www.expedia.co.uk/Canadys-Hotels.d3000455879.Travel-Guide-Hotels) - [Hotels near Congaree National Park ](https://www.expedia.co.uk/Congaree-National-Park-Hotels.0-l6129970-0.Travel-Guide-Filter-Hotels) - [Cordova Hotels ](https://www.expedia.co.uk/Cordova-Hotels.d553248634998610573.Travel-Guide-Hotels) - [Cross Hotels ](https://www.expedia.co.uk/Cross-Hotels.d3000455898.Travel-Guide-Hotels) - [Davis Station Hotels ](https://www.expedia.co.uk/Davis-Station-Hotels.d3000455905.Travel-Guide-Hotels) - [Calhoun County Hotels ](https://www.expedia.co.uk/Destinations-In-Calhoun-County.d553248635976434085.Hotel-Destinations) - [Elloree Hotels ](https://www.expedia.co.uk/Elloree-Hotels.d3000455923.Travel-Guide-Hotels) - [Gadsden Hotels ](https://www.expedia.co.uk/Gadsden-Hotels.d3000455935.Travel-Guide-Hotels) - [Greeleyville Hotels ](https://www.expedia.co.uk/Greeleyville-Hotels.d3000455948.Travel-Guide-Hotels) - [Harleyville Hotels ](https://www.expedia.co.uk/Harleyville-Hotels.d6046883.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://www.expedia.co.uk/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Hotels near I.P. 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