Title: Hotels in Santee, SC - Best Santee Hotels from £46 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d9953.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d9953.Car-Hire-Guide)[Santee Holidays](https://expedia.co.uk/Santee.d9953.Holidays-City-Breaks) ![Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines](https://images.trvl-media.com/place/9953/712fb946-715a-4a74-8bf7-2c2bbd891023.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santee, SC from £46 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santee Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-01-02&d1=2026-01-02&endDate=2026-01-04&d2=2026-01-04&amenities=POOL) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-01-02&d1=2026-01-02&endDate=2026-01-04&d2=2026-01-04&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-01-02&d1=2026-01-02&endDate=2026-01-04&d2=2026-01-04&lodging=CONDO) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-01-02&d1=2026-01-02&endDate=2026-01-04&d2=2026-01-04&travelerType=family_friendly) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-01-02&d1=2026-01-02&endDate=2026-01-04&d2=2026-01-04&lodging=COTTAGE) ## Check prices for these dates Tonight [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-12-20&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santee hotels ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1001) "Staff very friendly, room super clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karine £100 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/e757bdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/65520f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1002) "Rooms are clean, friendly staff and easy to get off and back on the highway. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £111 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/442e4efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (975) "Was able to walk to convenience store and other dinning alternatives. Safe secure building" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan £86 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (641) "Nice place to stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Tanya £87 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1000) "Nice rooms and very good breakfast items." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £98 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/ddfa8a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1001) "Staff was pleasant and helpful with restaurant information, room clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £85 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1416) "Very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramil £66 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/756c72ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.0/10 Good (678) "The room was very nice. It was newly renovated and I loved the upgrade. The beds were comfortable and warm. We didn’t eat breakfast because we were meeting someone for breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alice £51 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/e9087580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/b105c391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (637) "It's a good stop for the price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martin £58 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/60673add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/3b5b7fa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) Santee 6.4/10 (309) "Last minute arrangements stay was quiet and peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iasia £52 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/315e8dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (440) "The staff was very friendly and helpful. Room was clean and beds were so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy £62 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/ccd798ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/c97df40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (455) "exellent service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mirjana £49 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/23463ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/61b41f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/740d6803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 [](https://www.expedia.co.uk/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) Santee 6.2/10 (542) "The grounds and property were clean and you could tell they take pride in what they're offering." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £60 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 9.0/10 Wonderful (673) "The room was perfect and the staff was friendly and welcoming " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Milton £87 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/8a3bfd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/f127cd7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/ab9e6646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Manning [](https://www.expedia.co.uk/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) Manning 8.4/10 Very good (1001) "Staff is always super friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kirk £99 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/77c6db86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) Orangeburg 8.2/10 Very good (1002) "Enjoyed our stay " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Marie £66 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/0ca73b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e307c591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/fb97cba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning [](https://www.expedia.co.uk/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) Manning 8.6/10 Excellent (1000) "Easy check in and out. Friendly staff, quiet and cozy. Breakfast is average but plenty to choose from. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica £70 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Private kitchen](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/a4a585ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/795ddf27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchenette](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9d898fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/495c8e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.co.uk/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (80) "Room was clean with a beautiful view of the Lake." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melanie [](https://www.expedia.co.uk/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/8f5fb158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11093b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/e6902cd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (633) "Room was clean and the staff were good. Overall I would recommend this hotel!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) George £55 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f8fbcf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/6dc9f9a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/c7fdb599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (697) "The staff was great and the room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juillet £70 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-03&endDate=2026-01-04®ionId=9953&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels) ## Stay near popular Santee attractions ### Santee State Park 4.0/5 (112 reviews) Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6140632) ### Santee Cooper Country Club 3.9/5 (47 reviews) This George Cobb-designed course winds through majestic pines with strategic doglegs and panoramic Lake Marion views. Enjoy the signature closing hole and well-maintained fairways perfect for golfers of all skill levels. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654899) ### Santee National Golf Club 3.8/5 (43 reviews) This championship course blends Lowcountry charm with highland terrain, featuring moss-draped oaks and pristine bunkers. Enjoy diverse play with wide-open front nine and wooded back nine challenges. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654897) ## Learn more about Santee Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites. [See all hotels in Santee](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-03&endDate=2026-01-04&adults=2®ionId=9953) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=899&h=634&p=1&q=high) ## Top Santee Hotel Reviews ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "The hotel was easy to get to and the staff was wonderful. The bed was soooo comfortable. " [](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 10/10 Excellent "Clean , staff very courteous. Pet friendly!clean, friendly, on the beach, dog friendly beach area" [](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Wyndham Vacation Resorts Lake Marion](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8_y.jpg) ### Wyndham Vacation Resorts Lake Marion 10/10 Excellent "Excellent " [](https://expedia.co.uk/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 10/10 Excellent "Was able to walk to convenience store and other dinning alternatives. Safe secure building" [](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "The room was spotless and the bed was very comfortable. We went out for the day, we were surprised that our bed was made and had clean towels. " [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Charming 2 Bedroom Waterfront Lake Marion Condo](https://images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/c68f4c0f_y.jpg) ### Charming 2 Bedroom Waterfront Lake Marion Condo 10/10 Excellent "The host was attentive and responsive, even inviting us to check in earlier. The home was lovely, well-cared for and thoughtfully appointed. The small touches, such as a basket of coffee and filters along with some snacks allowed us to have coffee the next morning despite getting into town when the stores were closed. We will absolutely return to this property and feel comfortable recommending it others. " [](https://expedia.co.uk/Santee-Hotels-Charming-2-Bedroom-Waterfront-Lake-Marion-Condo.h112149977.Hotel-Information) ![Waterfront Condo on Lake Marion](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/fb378afa_y.jpg) ### Waterfront Condo on Lake Marion 10/10 Excellent "We live in Charleston, but wanted to get away for the weekend. This place is absolutely beautiful, we had an amazing time. The decorations are thoughtful and the layout is perfect. We loved that everyone had their own bathroom and that the shared space was very open. The kitchen (gorgeous) is well stocked with everything I needed to be able to cook family meals. The view of the lake was so peaceful and the property has plenty to do. Everyone that works there is so kind and goes above and beyond to make sure your stay is enjoyable. The pool was very clean and well maintained and the events that they hosted each day were impressive. The kids enjoyed the sno cones and movie by the pool. Kelly was very responsive when we had a question - thank you, we will be back! " [](https://expedia.co.uk/Santee-Hotels-Spacious-Condo-On-Beautiful-Lake-Marion.h102018216.Hotel-Information) ![Lake Marion - Majestic Big Water View! ](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/64e8f8c3_y.jpg) ### Lake Marion - Majestic Big Water View! 10/10 Excellent "Pool and lakeside very relaxing" [](https://expedia.co.uk/Santee-Hotels-Lake-Marion-Majestic-Big-Water-View.h104211609.Hotel-Information) ## More cheap stays in Santee ![Baymont by Wyndham Orangeburg North](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Orangeburg North 3583 Saint Matthews Rd Orangeburg SC £46 25 Dec - 26 Dec includes taxes & fees 6/10 (1,002 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Super 8 by Wyndham, Orangeburg](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham, Orangeburg 3608 Saint Matthews Rd Orangeburg SC £48 21 Dec - 22 Dec includes taxes & fees 6.8/10 (894 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC £66 21 Dec - 22 Dec includes taxes & fees 7.8/10 Good! (1,415 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn by Marriott Orangeburg 663 Citadel Road Orangeburg SC £70 28 Dec - 29 Dec includes taxes & fees 8.2/10 Very Good! (696 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC £87 4 Jan - 5 Jan 2026 includes taxes & fees 9/10 Wonderful! (639 reviews) [](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Orangeburg 739 Citadel Road Orangeburg SC £88 4 Jan - 5 Jan 2026 includes taxes & fees 9/10 Wonderful! (1,003 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ## Find out more about Santee ### Top reasons to visit Santee - **Outdoor Activities:** Santee is a haven for outdoor enthusiasts, offering stunning scenery in national and state parks, ideal for hiking and picnicking. - **Golf Courses:** Enjoy a round of golf at local courses, surrounded by beautiful landscapes and a relaxed atmosphere. - **Relaxing Lakes:** Nearby lakes and sandy beaches provide perfect spots for leisure and romantic getaways. - **Southern Hospitality:** Experience the warm, welcoming atmosphere and friendly locals that characterise Santee. - **Varied Accommodation:** Choose from a range of hotels and motels, catering to different traveller needs and preferences. ### Find great hotels in Santee Explore a variety of hotel accommodation options in Santee, South Carolina, ideal for every traveller. From welcoming motels to well-appointed hotels, you'll find the perfect fit for your needs, whether you're seeking pet-friendly amenities, a business-focused environment, or an LGBTQIA-friendly atmosphere. Discover the best Santee hotels that offer comfort and convenience for your memorable stay in this charming town. - **[Best Western Plus Santee Inn: ](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)** Nestled in the heart of Santee, the Best Western Plus Santee Inn caters to business travellers seeking a practical yet comfortable stay. This hotel offers a range of facilities, including a fully-equipped Business Centre and versatile Meeting Rooms ideal for conferences. Notably, it welcomes pets, ensuring your furry companions can accompany you on your travels. With amenities such as a dedicated Dog Exercise Area and a pet-friendly policy for dogs and cats, this hotel strikes a balance between professional needs and family-friendly accommodation. - **[Hampton Inn Santee-I-95: ](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)** The Hampton Inn Santee-I-95 prides itself on being an inclusive retreat for all guests, including those with pets. This hotel boasts a warm and welcoming atmosphere, with a commitment to LGBTQIA+ travellers. It features a variety of amenities designed for comfort and convenience, including complimentary breakfast and a fitness centre. The pet policy allows for dogs and cats, with a variable fee, making it an ideal stop for pet owners looking for a friendly environment. Enjoy a pleasant stay that feels like home while exploring Santee. - **[Travelodge by Wyndham Santee: ](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)** The Travelodge by Wyndham Santee is a straightforward and budget-friendly option for those travelling with pets. Situated conveniently in Santee, this hotel provides essential amenities for a comfortable stay, including free Wi-Fi and parking. The pet-friendly policy allows you to bring your dogs along, ensuring a hassle-free experience for pet owners. With its emphasis on affordability and convenience, the Travelodge is perfect for families and travellers seeking a relaxed atmosphere without compromising on comfort. ### Where to stay near Santee Santee, South Carolina, offers a delightful blend of outdoor activities and Southern hospitality. Explore the scenic lakes and sandy beaches nearby, perfect for a romantic getaway or family excursion. Discover the friendly atmosphere and budget-friendly attractions that define this charming city. From its picturesque surroundings to local excursions, Santee promises a memorable vacation experience for every traveller. - **[Summerton: ](https://www.expedia.co.uk/Summerton-Hotels.d163488.Travel-Guide-Hotels)** Situated 6.8km from Santee, Summerton is a charming city that beckons visitors with its picturesque outdoor scenery and romantic ambiance. Though traveller arrivals fluctuate throughout the year, the peak seasons in March to April and July draw those eager to explore its recreational areas and well-maintained golf courses. The local attractions, including serene lakes and the nearby national state park, offer ample opportunities for relaxation and adventure, making Summerton an appealing destination for nature lovers and couples alike. - **[Vance: ](https://www.expedia.co.uk/Vance-Hotels.d3000456153.Travel-Guide-Hotels)** A mere 3.1km from Santee, Vance is a delightful city known for its highly seasonal influx of visitors. The bustling periods in March to April and July invite outdoor enthusiasts to experience the stunning landscapes and recreational opportunities available. With a focus on golfing and exploration, Vance’s proximity to beautiful lakes and national parks, including scenic islands, makes it a perfect spot for those seeking a romantic getaway or an invigorating outdoor experience. Expect a warm welcome and an abundance of activities during your visit! - **[Elloree: ](https://www.expedia.co.uk/Elloree-Hotels.d3000455923.Travel-Guide-Hotels)** Located 3.7km from Santee, Elloree is a quaint city that offers a blend of outdoor beauty and romantic settings. Although visitor numbers are fairly steady throughout the year, peak seasons in March, July, and September provide an ideal backdrop for travellers seeking adventure. Explore the local recreational areas, golf courses, and the captivating natural surroundings, including lakes and national parks. Whether you’re planning a peaceful retreat or an active holiday, Elloree promises an unforgettable experience in the heart of South Carolina. ### Things to do in and around Santee Santee, South Carolina, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy a range of activities including exploring recreational areas and playing a round of golf at the local golf courses. The charming scenery provides a perfect backdrop for relaxation and adventure, making Santee a delightful spot for a vacation. **Shopping** In Santee, visit the Santee Outlets for a variety of shops in a lively atmosphere. If you're up for a drive, check out Pocalla Crossing Shopping Center, 16.8km away, for more shopping options, or Bee City, located 18.6km from Santee, for unique gifts. **Recreation** Enjoy a round of golf at Santee Cooper Country Club, where you can relish the outdoors amidst lush greens. For a tranquil escape, visit Santee National Wildlife Refuge, offering serene nature trails and wildlife observation. Alternatively, unwind at Patriots Sports Plex, featuring various recreational activities for relaxation. **Adventure** Santee State Park offers stunning views and a wealth of outdoor activities, including hiking trails along Lake Marion, fishing, and birdwatching. For a thrilling time, venture to the Santee National Wildlife Refuge, where you can explore diverse wildlife and scenic landscapes perfect for photography and nature walks. **Nightlife** Santee boasts a laid-back nightlife with charming venues like the Lake Marion Golf Club, where you can enjoy a relaxed evening with friends over drinks. The local bars often feature live music, creating a vibrant atmosphere perfect for unwinding after a day of exploring. ### Booking tips and Expedia advantages for Santee When visiting Santee, South Carolina, there are several ways to save money. Enjoy free activities like exploring Taw Caw Creek and take advantage of the free entry to public areas. For transport, consider using a bike or an affordable bus service. The cheapest months to visit are December to February, with Mondays often offering the best hotel rates. Use Expedia to compare prices, find great deals, and book packages that combine flights, hotels, and activities for additional savings. Look for eco-certified hotels to save while supporting sustainability. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to set your budget, choose your desired location, and much more. You can organise your results to display prices from lowest to highest, allowing you to find the most affordable hotels first. Additionally, you have the option to refine your search by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking. - **Consider bundling your trip:** You can potentially save money by combining your hotel reservation in Santee with your flights and activities through an Expedia package. ### Find the best attractions in and around Santee Santee, South Carolina, is perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitors can enjoy the stunning scenery at nearby national and state parks, as well as relaxing at local lakes and islands. With a variety of attractions catering to outdoor activities, beach relaxation, and cultural experiences, Santee promises a delightful vacation for all types of travellers. - **Santee State Park:** Immerse yourself in the natural beauty of Santee State Park, where outdoor enthusiasts can enjoy hiking, fishing, and camping amidst scenic landscapes and tranquil vibes. The park offers a perfect escape for adventure seekers and nature lovers alike. - **Santee Town Hall:** Visit Santee Town Hall to appreciate its architectural charm and learn about the local governance. This hub of community activity provides insight into the town’s business and civic life, making it a unique spot for understanding Santee’s culture. - **Taw Caw Creek:** Located 5.6km from Santee, Taw Caw Creek is a picturesque lake, ideal for romantic outings and serene picnics. Enjoy the stunning views, sandy beaches, and outdoor activities that make it a perfect retreat for couples and families. ### Best time to go to Santee The best time to visit Santee is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 47.3°F (8.5°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 51.4°F (10.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 56.8°F (13.8°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | April | 64.4°F (18.0°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | May | 72.0°F (22.2°C) | Light Rain | Mostly Sunny | Average | Average | | June | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 79.9°F (26.6°C) | Light Rain | Mostly Sunny | Average | Average | | September | 75.4°F (24.1°C) | Light Rain | Mostly Sunny | Average | Average | | October | 66.4°F (19.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 56.1°F (13.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | December | 51.3°F (10.7°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Santee When planning your visit to Santee, South Carolina, you can fly into two major airports. Charleston International Airport ([CHS](https://www.expedia.co.uk/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is situated 30.4km away, with excellent hotel options like [The Charleston Place](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information), [Hotel Bennett](https://www.expedia.co.uk/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), and [The Dewberry Charleston](https://www.expedia.co.uk/Charleston-Hotels-The-Dewberry-Charleston.h12880056.Hotel-Information), all offering transportation services to the airport. Alternatively, Columbia Metropolitan Airport ([CAE](https://www.expedia.co.uk/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels)) is also 30.4km from Santee, featuring hotels such as [Graduate by Hilton Columbia SC](https://www.expedia.co.uk/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information), [Doubletree by Hilton Columbia](https://www.expedia.co.uk/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information), and [Marriott Columbia](https://www.expedia.co.uk/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information), all conveniently located for easy access to the airport. Both airports provide a range of services to ensure a smooth start to your holiday. ## Frequently asked questions ### What are the best hotels in Santee that travellers recommend? ### What are the best family hotels in Santee? ### What are the top pet-friendly hotels in Santee? ### What are the best budget hotels in Santee? > Another excellent choice is the [Hampton Inn Santee-I-95](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information), rated 9.6 by guests. This property also features an outdoor seasonal pool and offers free breakfast, creating the great start to a day of adventure. With spacious rooms equipped with cribs and rollaway beds, families can comfortably settle in without worry. > > > Couples looking for a cozy retreat may also enjoy the [Best Western Plus Santee Inn](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information), which, while slightly lower on the review scale at 8.8, boasts a charming atmosphere with an indoor hot tub and kitchen facilities for added convenience. > > > Each of these hotels provides a friendly and accommodating experience, allowing travellers to focus on their adventures while enjoying quality service without stretching their budget. View all [budget hotels in Santee](https://www.expedia.co.uk/santee-hotels-budget-hotels.0-0-d9953-tbudgethotels.travel-guide-filter-hotels). ### When is the best time to go to Santee? > Santee experiences its peak season from March to May, attracting a steady flow of tourists eager to partake in various activities. The mild climate during this period is particularly inviting for hiking, biking, and even fishing in the nearby lakes. With the lush greenery in full bloom, it's an excellent time to explore the natural beauty surrounding the area. > > > For families and couples alike, April is an especially appealing month. The community often hosts local events and festivals that provide a wonderful opportunity to engage with residents and immerse yourself in the local culture. You can enjoy picnics in the park, stroll along the trails, or take part in outdoor sports, all while basking in the pleasant sun. > > > If you're looking for a more budget-friendly option, consider visiting in November. While the weather may be cooler, it offers a unique perspective on Santee's charm, and you can often find lower accommodation rates during this time. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santee hotel booking with Expedia? ### How much is the nightly rate at a Santee hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [3 Star Hotels in Davis Station ](https://www.expedia.co.uk/3Star-Davis-Station-Hotels.s30-0-d3000455905.Travel-Guide-Filter-Hotels) - [Alcolu Hotels ](https://www.expedia.co.uk/Alcolu-Hotels.d3000422483.Travel-Guide-Hotels) - [Marriott Hotels & Resorts in Bamberg ](https://www.expedia.co.uk/Bamberg-Hotels-Marriott-Hotels-Resorts.0-0-d55570--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Bowman Hotels ](https://www.expedia.co.uk/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Branchville Hotels ](https://www.expedia.co.uk/Branchville-Hotels.d3000455875.Travel-Guide-Hotels) - [Brookdale Hotels ](https://www.expedia.co.uk/Brookdale-Hotels.d553248634999003908.Travel-Guide-Hotels) - [Cameron Hotels ](https://www.expedia.co.uk/Cameron-Hotels.d553248634998916920.Travel-Guide-Hotels) - [Canadys Hotels ](https://www.expedia.co.uk/Canadys-Hotels.d3000455879.Travel-Guide-Hotels) - [Hotels near Congaree National Park ](https://www.expedia.co.uk/Congaree-National-Park-Hotels.0-l6129970-0.Travel-Guide-Filter-Hotels) - [Cordova Hotels ](https://www.expedia.co.uk/Cordova-Hotels.d553248634998610573.Travel-Guide-Hotels) - [Cross Hotels ](https://www.expedia.co.uk/Cross-Hotels.d3000455898.Travel-Guide-Hotels) - [Davis Station Hotels ](https://www.expedia.co.uk/Davis-Station-Hotels.d3000455905.Travel-Guide-Hotels) - [Calhoun County Hotels ](https://www.expedia.co.uk/Destinations-In-Calhoun-County.d553248635976434085.Hotel-Destinations) - [Elloree Hotels ](https://www.expedia.co.uk/Elloree-Hotels.d3000455923.Travel-Guide-Hotels) - [Gadsden Hotels ](https://www.expedia.co.uk/Gadsden-Hotels.d3000455935.Travel-Guide-Hotels) - [Greeleyville Hotels ](https://www.expedia.co.uk/Greeleyville-Hotels.d3000455948.Travel-Guide-Hotels) - [Harleyville Hotels ](https://www.expedia.co.uk/Harleyville-Hotels.d6046883.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://www.expedia.co.uk/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Hotels near I.P. 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