Title: Hotels in Santee, SC - Best Santee Hotels from £43 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d9953.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d9953.Car-Hire-Guide)[Santee Holidays](https://expedia.co.uk/Santee.d9953.Holidays-City-Breaks) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santee, SC from £43 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santee Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=PETS) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=CABIN) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=APARTMENT) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=COTTAGE) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&travelerType=family_friendly) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=WATER_PARK) ## Check prices for these dates Tonight [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [5 Nov - 6 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santee hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/828f10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee Santee 9.2/10 Wonderful (583) "Clean, safe and very comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard £95 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1388) "A nice location, plenty of parking, nice that breakfast was included. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alyssa £63 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/ddfa8a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee Santee 8.0/10 Very good (1003) "Good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) omar £90 includes taxes & fees 17 Nov - 18 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/e757bdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/65520f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 Santee 9.6/10 Exceptional (1004) "Very nice hotel, very clean and super friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £102 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1004) "Great stay for a quick weekend getaway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle £102 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/e27bc6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG Santee 8.2/10 Very good (958) "Great hotel w" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth £100 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/756c72ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee Santee 7.0/10 Good (664) "Clean, comfortable, convenient stop on highway " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William Brian £52 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/ccd798ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/c97df40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/10951979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee 6.0/10 (445) "Clean n great owners " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stefan £57 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/dc9ab090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn Santee 8.8/10 Excellent (1002) "The breakfast was good and people helpful and nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £115 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/740d6803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/23463ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 Santee 6.2/10 (538) "The grounds and property were clean and you could tell they take pride in what they're offering." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £59 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/a90b57ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/e9087580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee Santee 6.6/10 (632) "It's a quiet tuck back hotel. Although the front desk lady was extremely rude and tried to over charge me several times. The property manager was very professional." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica £53 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/315e8dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee Santee 6.8/10 (436) "It's a very quiet hotel. My room was very spacious. And the bed was very comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica £63 includes taxes & fees 6 Nov - 7 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/3b5b7fa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/51caeaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee 6.4/10 (309) "It was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £53 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/57735ca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1018) "It was nice and staff was very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £89 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/321b05a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg Orangeburg 7.8/10 Good (1009) "Rooms were clean and comfortable. Can’t speak to the breakfast as we had to leave before it opened, but overall we had a great peaceful sleep. Would definitely recommend staying there. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Martina £74 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/5fe5c871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/208c4454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg Orangeburg 8.0/10 Very good (529) "I was satisfied with staff service and facilities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gwendolyn £83 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/a66aad1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/816f12dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e85d0e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George St. George 7.6/10 Good (1007) "Very pleasant stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annie £55 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/e1b5940b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/8a3bfd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/ab9e6646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Manning Manning 8.4/10 Very good (990) "Clean Easy room access, spacious couch and comfortable king bed combination room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika £101 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/97d6098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/5e401dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/a152b78a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/159dba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Orangeburg Orangeburg 7.8/10 Good (372) "Friendly, helpful staff. Room is very nice, clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori £71 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e307c591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/b76457c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/0ca73b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning Manning 8.6/10 Excellent (1006) "Parking ok, breakfast ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ada £80 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=9953&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels) ## Stay near popular Santee attractions [](https://www.expedia.co.uk/Santee-State-Park-Hotels.0-l6140632-0.Travel-Guide-Filter-Hotels) ### Santee State Park 4.0/5 (112 reviews) You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6140632) [](https://www.expedia.co.uk/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) ### Santee Cooper Country Club 3.9/5 (47 reviews) Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654899) [](https://www.expedia.co.uk/Santee-National-Golf-Club-Hotels.0-l553248621532654897-0.Travel-Guide-Filter-Hotels) ### Santee National Golf Club 3.8/5 (43 reviews) Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654897) [](https://www.expedia.co.uk/Santee-Town-Hall-Hotels.0-l911209496341475328-0.Travel-Guide-Filter-Hotels) ### Santee Town Hall Santee Town Hall is just one of the places to see in Santee, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911209496341475328) ## Learn more about Santee Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites. [See all hotels in Santee](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&adults=2®ionId=9953) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=899&h=634&p=1&q=high) ## Top Santee Hotel Reviews ![Hampton Inn Santee-I-95](//images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Breakfast looked excellent " [](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Best Western Plus Santee Inn](//images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "Room was nice and friendly staff!" [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Holiday Inn Santee by IHG](//images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 10/10 Excellent "Great hotel w" [](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Travelodge by Wyndham Santee](//images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 10/10 Excellent "The counter tops and appliances needed cleaning, they were greasy. Otherwise the room was okay." [](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Charming 2 Bedroom Waterfront Lake Marion Condo](//images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/c68f4c0f_y.jpg) ### Charming 2 Bedroom Waterfront Lake Marion Condo 10/10 Excellent "Fantastic location on the lake and access to the pool as well. Home was clean and had everything we needed for our stay. Amazing communication with the owner. Will stay again." [](https://expedia.co.uk/Santee-Hotels-Charming-2-Bedroom-Waterfront-Lake-Marion-Condo.h112149977.Hotel-Information) ![Lake Marion - Majestic Big Water View! ](//images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/64e8f8c3_y.jpg) ### Lake Marion - Majestic Big Water View! 10/10 Excellent "Pool and lakeside very relaxing" [](https://expedia.co.uk/Santee-Hotels-Lake-Marion-Majestic-Big-Water-View.h104211609.Hotel-Information) ![Sunsets on Lake Marion](//images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/c4bbcdf8_y.jpg) ### Sunsets on Lake Marion 10/10 Excellent "We enjoyed staying at this beautiful condo. It was very spacious. We only had a couple complaints. The fridge didnt get very cold. The neighbor that was next to us his dog barked all night. There was also a man that was harassing us throughout the stay also talking to me 12 year old while she was outside. He seemed to be drunk but lives there. The condo its self was perfect! My family had a great 4th of July staying here. " [](https://expedia.co.uk/Santee-Hotels-Sunsets-On-Lake-Marion.h107294387.Hotel-Information) ![Wyndham Vacation Resorts Lake Marion](//images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8_y.jpg) ### Wyndham Vacation Resorts Lake Marion 10/10 Excellent "Friendly staff. Excellent accomodations. Peaceful and beautiful vacation." [](https://expedia.co.uk/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information) ## More cheap stays in Santee ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street, Santee, SC £63 5 Nov - 6 Nov includes taxes & fees 7.8/10 Good! (1,381 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St., Santee, SC £95 16 Nov - 17 Nov includes taxes & fees 9/10 Wonderful! (581 reviews) [](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Orangeburg 739 Citadel Road, Orangeburg, SC £89 25 Nov - 26 Nov includes taxes & fees 9/10 Wonderful! (1,010 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Baymont by Wyndham Orangeburg North](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Orangeburg North 3583 Saint Matthews Rd, Orangeburg, SC £43 16 Nov - 17 Nov includes taxes & fees 6/10 (1,004 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy, Santee, SC £102 4 Dec - 5 Dec includes taxes & fees 9.8/10 Exceptional! (1,003 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Spark by Hilton Orangeburg 731 Citadel Road, Orangeburg, SC £74 13 Nov - 14 Nov includes taxes & fees 7.6/10 Good! (1,002 reviews) [](https://expedia.co.uk/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ## Find out more about Santee ### Top reasons to visit Santee - **Outdoor Activities:** Santee is a haven for outdoor enthusiasts, offering stunning scenery in national and state parks, ideal for hiking and picnicking. - **Golf Courses:** Enjoy a round of golf at local courses, surrounded by beautiful landscapes and a relaxed atmosphere. - **Relaxing Lakes:** Nearby lakes and sandy beaches provide perfect spots for leisure and romantic getaways. - **Southern Hospitality:** Experience the warm, welcoming atmosphere and friendly locals that characterise Santee. - **Varied Accommodation:** Choose from a range of hotels and motels, catering to different traveller needs and preferences. ### Find great hotels in Santee Explore a variety of hotel accommodation options in Santee, South Carolina, ideal for every traveller. From welcoming motels to well-appointed hotels, you'll find the perfect fit for your needs, whether you're seeking pet-friendly amenities, a business-focused environment, or an LGBTQIA-friendly atmosphere. Discover the best Santee hotels that offer comfort and convenience for your memorable stay in this charming town. - **[Best Western Plus Santee Inn:](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)** Nestled in the heart of Santee, the Best Western Plus Santee Inn caters to business travellers seeking a practical yet comfortable stay. This hotel offers a range of facilities, including a fully-equipped Business Centre and versatile Meeting Rooms ideal for conferences. Notably, it welcomes pets, ensuring your furry companions can accompany you on your travels. With amenities such as a dedicated Dog Exercise Area and a pet-friendly policy for dogs and cats, this hotel strikes a balance between professional needs and family-friendly accommodation. - **[Hampton Inn Santee-I-95:](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)** The Hampton Inn Santee-I-95 prides itself on being an inclusive retreat for all guests, including those with pets. This hotel boasts a warm and welcoming atmosphere, with a commitment to LGBTQIA+ travellers. It features a variety of amenities designed for comfort and convenience, including complimentary breakfast and a fitness centre. The pet policy allows for dogs and cats, with a variable fee, making it an ideal stop for pet owners looking for a friendly environment. Enjoy a pleasant stay that feels like home while exploring Santee. - **[Travelodge by Wyndham Santee:](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)** The Travelodge by Wyndham Santee is a straightforward and budget-friendly option for those travelling with pets. Situated conveniently in Santee, this hotel provides essential amenities for a comfortable stay, including free Wi-Fi and parking. The pet-friendly policy allows you to bring your dogs along, ensuring a hassle-free experience for pet owners. With its emphasis on affordability and convenience, the Travelodge is perfect for families and travellers seeking a relaxed atmosphere without compromising on comfort. ### Where to stay near Santee Santee, South Carolina, offers a delightful blend of outdoor activities and Southern hospitality. Explore the scenic lakes and sandy beaches nearby, perfect for a romantic getaway or family excursion. Discover the friendly atmosphere and budget-friendly attractions that define this charming city. From its picturesque surroundings to local excursions, Santee promises a memorable vacation experience for every traveller. - **[Summerton:](https://www.expedia.co.uk/Summerton-Hotels.d163488.Travel-Guide-Hotels)** Situated 6.8km from Santee, Summerton is a charming city that beckons visitors with its picturesque outdoor scenery and romantic ambiance. Though traveller arrivals fluctuate throughout the year, the peak seasons in March to April and July draw those eager to explore its recreational areas and well-maintained golf courses. The local attractions, including serene lakes and the nearby national state park, offer ample opportunities for relaxation and adventure, making Summerton an appealing destination for nature lovers and couples alike. - **[Vance:](https://www.expedia.co.uk/Vance-Hotels.d3000456153.Travel-Guide-Hotels)** A mere 3.1km from Santee, Vance is a delightful city known for its highly seasonal influx of visitors. The bustling periods in March to April and July invite outdoor enthusiasts to experience the stunning landscapes and recreational opportunities available. With a focus on golfing and exploration, Vance’s proximity to beautiful lakes and national parks, including scenic islands, makes it a perfect spot for those seeking a romantic getaway or an invigorating outdoor experience. Expect a warm welcome and an abundance of activities during your visit! - **[Elloree:](https://www.expedia.co.uk/Elloree-Hotels.d3000455923.Travel-Guide-Hotels)** Located 3.7km from Santee, Elloree is a quaint city that offers a blend of outdoor beauty and romantic settings. Although visitor numbers are fairly steady throughout the year, peak seasons in March, July, and September provide an ideal backdrop for travellers seeking adventure. Explore the local recreational areas, golf courses, and the captivating natural surroundings, including lakes and national parks. Whether you’re planning a peaceful retreat or an active holiday, Elloree promises an unforgettable experience in the heart of South Carolina. ### Things to do in and around Santee Santee, South Carolina, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy a range of activities including exploring recreational areas and playing a round of golf at the local golf courses. The charming scenery provides a perfect backdrop for relaxation and adventure, making Santee a delightful spot for a vacation. **Shopping** In Santee, visit the Santee Outlets for a variety of shops in a lively atmosphere. If you're up for a drive, check out Pocalla Crossing Shopping Center, 16.8km away, for more shopping options, or Bee City, located 18.6km from Santee, for unique gifts. **Recreation** Enjoy a round of golf at Santee Cooper Country Club, where you can relish the outdoors amidst lush greens. For a tranquil escape, visit Santee National Wildlife Refuge, offering serene nature trails and wildlife observation. Alternatively, unwind at Patriots Sports Plex, featuring various recreational activities for relaxation. **Adventure** Santee State Park offers stunning views and a wealth of outdoor activities, including hiking trails along Lake Marion, fishing, and birdwatching. For a thrilling time, venture to the Santee National Wildlife Refuge, where you can explore diverse wildlife and scenic landscapes perfect for photography and nature walks. **Nightlife** Santee boasts a laid-back nightlife with charming venues like the Lake Marion Golf Club, where you can enjoy a relaxed evening with friends over drinks. The local bars often feature live music, creating a vibrant atmosphere perfect for unwinding after a day of exploring. ### Booking tips and Expedia advantages for Santee When visiting Santee, South Carolina, there are several ways to save money. Enjoy free activities like exploring Taw Caw Creek and take advantage of the free entry to public areas. For transport, consider using a bike or an affordable bus service. The cheapest months to visit are December to February, with Mondays often offering the best hotel rates. Use Expedia to compare prices, find great deals, and book packages that combine flights, hotels, and activities for additional savings. Look for eco-certified hotels to save while supporting sustainability. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to set your budget, choose your desired location, and much more. You can organise your results to display prices from lowest to highest, allowing you to find the most affordable hotels first. Additionally, you have the option to refine your search by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking. - **Consider bundling your trip:** You can potentially save money by combining your hotel reservation in Santee with your flights and activities through an Expedia package. ### Find the best attractions in and around Santee Santee, South Carolina, is perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitors can enjoy the stunning scenery at nearby national and state parks, as well as relaxing at local lakes and islands. With a variety of attractions catering to outdoor activities, beach relaxation, and cultural experiences, Santee promises a delightful vacation for all types of travellers. - **Santee State Park:** Immerse yourself in the natural beauty of Santee State Park, where outdoor enthusiasts can enjoy hiking, fishing, and camping amidst scenic landscapes and tranquil vibes. The park offers a perfect escape for adventure seekers and nature lovers alike. - **Santee Town Hall:** Visit Santee Town Hall to appreciate its architectural charm and learn about the local governance. This hub of community activity provides insight into the town’s business and civic life, making it a unique spot for understanding Santee’s culture. - **Taw Caw Creek:** Located 5.6km from Santee, Taw Caw Creek is a picturesque lake, ideal for romantic outings and serene picnics. Enjoy the stunning views, sandy beaches, and outdoor activities that make it a perfect retreat for couples and families. ### Best time to go to Santee The best time to visit Santee is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 47.3°F (8.5°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 51.4°F (10.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 56.8°F (13.8°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | April | 64.4°F (18.0°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | May | 72.0°F (22.2°C) | Light Rain | Mostly Sunny | Average | Average | | June | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 79.9°F (26.6°C) | Light Rain | Mostly Sunny | Average | Average | | September | 75.4°F (24.1°C) | Light Rain | Mostly Sunny | Average | Average | | October | 66.4°F (19.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 56.1°F (13.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | December | 51.3°F (10.7°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Santee When planning your visit to Santee, South Carolina, you can fly into two major airports. Charleston International Airport ([CHS](https://www.expedia.co.uk/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is situated 30.4km away, with excellent hotel options like [The Charleston Place](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information), [Hotel Bennett](https://www.expedia.co.uk/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), and [The Dewberry Charleston](https://www.expedia.co.uk/Charleston-Hotels-The-Dewberry-Charleston.h12880056.Hotel-Information), all offering transportation services to the airport. Alternatively, Columbia Metropolitan Airport ([CAE](https://www.expedia.co.uk/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels)) is also 30.4km from Santee, featuring hotels such as [Graduate by Hilton Columbia SC](https://www.expedia.co.uk/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information), [Doubletree by Hilton Columbia](https://www.expedia.co.uk/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information), and [Marriott Columbia](https://www.expedia.co.uk/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information), all conveniently located for easy access to the airport. Both airports provide a range of services to ensure a smooth start to your holiday. ## Frequently asked questions ### What are the best hotels in Santee that travellers recommend? > [Holiday Inn Santee by IHG](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) stands out as a top choice for travellers, earning a review score of 8.2. This hotel combines comfort with convenience, making it a great option for groups and solo travellers. With spacious rooms and attentive service, guests feel right at home. The hotel features a ballroom for events and room service, ensuring that all your needs are met without hassle. ### What are the best family hotels in Santee? > [Holiday Inn Santee by IHG](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) stands out as an excellent family-friendly option in Santee, South Carolina, with an excellent traveller review rating of 8.2. This hotel offers spacious rooms that include cribs and connecting rooms, making it easy for families to stay close together while enjoying their own space. Find more [child-friendly accommodations in Santee](https://www.expedia.co.uk/Santee-Hotels-Family-Friendly-Hotel.0-0-d9953-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels). ### What are the top pet-friendly hotels in Santee? > [Holiday Inn Santee by IHG](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) is a fantastic option for pet-friendly travellers seeking a blend of comfort and convenience. This hotel welcomes small pets, ensuring that your furry friends can join in on the adventure. Guests appreciate the inviting indoor pool, great for a refreshing dip after a day of exploring, and the nearby golf course offers a delightful opportunity for those looking to tee off amidst beautiful scenery. See more [pet-friendly hotels in Santee](https://www.expedia.co.uk/Santee-Hotels-Pet-Friendly-Hotel.0-0-d9953-tPetFriendlyHotel.Travel-Guide-Filter-Hotels). ### What are the best budget hotels in Santee? > For budget-conscious travellers seeking comfort and convenience in Santee, the Fairfield Inn & Suites by Marriott Santee stands out with an impressive guest review rating of 9.8. This hotel offers a delightful array of amenities, including complimentary breakfast options and free WiFi, ensuring a straightforward stay. Families will appreciate the outdoor pool, accessible fitness centre, and the availability of cribs and highchairs, making it a welcoming environment for kids. > > > > Another excellent choice is the [Hampton Inn Santee-I-95](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information), rated 9.6 by guests. This property also features an outdoor seasonal pool and offers free breakfast, creating the great start to a day of adventure. With spacious rooms equipped with cribs and rollaway beds, families can comfortably settle in without worry. > > > > Couples looking for a cozy retreat may also enjoy the [Best Western Plus Santee Inn](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information), which, while slightly lower on the review scale at 8.8, boasts a charming atmosphere with an indoor hot tub and kitchen facilities for added convenience. > > > > Each of these hotels provides a friendly and accommodating experience, allowing travellers to focus on their adventures while enjoying quality service without stretching their budget. View all [budget hotels in Santee](https://www.expedia.co.uk/santee-hotels-budget-hotels.0-0-d9953-tbudgethotels.travel-guide-filter-hotels). ### When is the best time to go to Santee? > The most popular time to visit Santee is April, when the weather begins to warm up, creating a delightful atmosphere for outdoor adventures. Temperatures typically range from 15 to 24 Celsius, making it superb for enjoying the beautiful parks and scenic landscapes that the area has to offer. > > > > Santee experiences its peak season from March to May, attracting a steady flow of tourists eager to partake in various activities. The mild climate during this period is particularly inviting for hiking, biking, and even fishing in the nearby lakes. With the lush greenery in full bloom, it's an excellent time to explore the natural beauty surrounding the area. > > > > For families and couples alike, April is an especially appealing month. The community often hosts local events and festivals that provide a wonderful opportunity to engage with residents and immerse yourself in the local culture. You can enjoy picnics in the park, stroll along the trails, or take part in outdoor sports, all while basking in the pleasant sun. > > > > If you're looking for a more budget-friendly option, consider visiting in November. While the weather may be cooler, it offers a unique perspective on Santee's charm, and you can often find lower accommodation rates during this time. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santee. ### How can I save on a Santee hotel booking with Expedia? > Members always get our best prices. Find our best Santee hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Santee hotel? > Prices for hotels in Santee often vary, but you can find a great deal from £43 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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