Title: South Carolina Boutique Hotels, United States of America: South Carolina Hotel Guide | Expedia.co.uk [South Carolina Travel Guide](https://expedia.co.uk/South-Carolina.dx242)[South Carolina Hotels](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Holiday Rentals in South Carolina](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations)[South Carolina Flights](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Hire](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Car-Hire-Destinations)[South Carolina Holidays](https://expedia.co.uk/South-Carolina.d242.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Carolina Accommodation: Most Popular Cities to Stay ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/553000/553975-charleston-sc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Charleston [](https://expedia.co.uk/Charleston-Hotels-Boutique-Hotel.0-0-d179997-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/494000/494078-myrtle-beach.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Myrtle Beach [](https://expedia.co.uk/Myrtle-Beach-Hotels-Boutique-Hotel.0-0-d601685-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ![Greenville featuring a bridge, a city and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.co.uk/Greenville-Hotels-Boutique-Hotel.0-0-d1388-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina Boutique Hotels Tonight [15 Jan - 16 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-15&endDate=2026-01-16&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [16 Jan - 17 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-16&endDate=2026-01-17&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina boutique hotels ![Restaurant](https://images.trvl-media.com/lodging/4000000/3300000/3296100/3296061/82a1bce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/4000000/3300000/3296100/3296061/81919ab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Bedroom Residence | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/4000000/3300000/3296100/3296061/909477ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom Residence | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/4000000/3300000/3296100/3296061/d4ff327b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Restoration [](https://www.expedia.co.uk/Charleston-Hotels-The-Restoration.h3296061.Hotel-Information) Charleston Historic District 9.6/10 Exceptional (1,002 reviews) "Wonderful stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suzanne £206 includes taxes & fees 22 Jan - 23 Jan [](https://www.expedia.co.uk/Charleston-Hotels-The-Restoration.h3296061.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/180000/172500/172457/479591d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/180000/172500/172457/59c66cc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/172500/172457/0cd9d6c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/180000/172500/172457/f7ab29bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Vendue [](https://www.expedia.co.uk/Charleston-Hotels-The-Vendue.h172457.Hotel-Information) Charleston Historic District 9.4/10 Exceptional (816 reviews) "Great staff, very clean rooms, near everything!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan £173 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Charleston-Hotels-The-Vendue.h172457.Hotel-Information) ![Gym](https://images.trvl-media.com/lodging/1000000/870000/869100/869045/6b5dd826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and lunch served, American cuisine](https://images.trvl-media.com/lodging/1000000/870000/869100/869045/76eb48ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869100/869045/5dc6f53d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/870000/869100/869045/698fca9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Loft Hotel [](https://www.expedia.co.uk/Beaufort-Hotels-City-Loft-Hotel.h869045.Hotel-Information) Historic District 9.4/10 Exceptional (762 reviews) "Staff was fantastic and room was spotless." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £110 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Beaufort-Hotels-City-Loft-Hotel.h869045.Hotel-Information) ![Café](https://images.trvl-media.com/lodging/18000000/17570000/17565600/17565555/fc3c99f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/18000000/17570000/17565600/17565555/51b1d809.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/18000000/17570000/17565600/17565555/d2ead0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/18000000/17570000/17565600/17565555/4570769f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 86 Cannon Charleston - Adults Only [](https://www.expedia.co.uk/Charleston-Hotels-86-Cannon-Historic-Inn-Adults-Only.h17565555.Hotel-Information) Downtown Charleston 10/10 Exceptional (72 reviews) "The perfect place to stay if your visiting Charleston " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £341 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Charleston-Hotels-86-Cannon-Historic-Inn-Adults-Only.h17565555.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/3000000/2170000/2169500/2169413/896a75c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/3000000/2170000/2169500/2169413/267c98cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2170000/2169500/2169413/1e06a61a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bay Street Three Bedroom Flat | Balcony](https://images.trvl-media.com/lodging/3000000/2170000/2169500/2169413/e0257b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beaufort Inn [](https://www.expedia.co.uk/Beaufort-Hotels-Beaufort-Inn.h2169413.Hotel-Information) Downtown Beaufort 9.0/10 Wonderful (1,000 reviews) "Nice, accommodating, beautiful decor, convenient, great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine £111 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/Beaufort-Hotels-Beaufort-Inn.h2169413.Hotel-Information) ![Anson Suite | Frette Italian sheets, premium bedding, Tempur-Pedic beds, in-room safe](https://images.trvl-media.com/lodging/6000000/5500000/5494400/5494363/08275705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/6000000/5500000/5494400/5494363/5fd5ff07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/6000000/5500000/5494400/5494363/ef5b1058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Three Bedroom Residence | Private kitchen | Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/6000000/5500000/5494400/5494363/2e9a74a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Zero George Street [](https://www.expedia.co.uk/Charleston-Hotels-Zero-George-Street.h5494363.Hotel-Information) Charleston Historic District 9.8/10 Exceptional (358 reviews) "A delightful stay in a delightful setting. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tommy £232 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Charleston-Hotels-Zero-George-Street.h5494363.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/46d9f65f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/e646e077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/698f2fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/af54d760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Planters Inn [](https://www.expedia.co.uk/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) Charleston Historic District 9.6/10 Exceptional (1,007 reviews) "It was a perfect stay. Great Location and room was incredible!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russell £187 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/920000/910100/910028/eade1e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/910100/910028/d9089ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/920000/910100/910028/3443731d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/920000/910100/910028/29072961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Market Pavilion Hotel [](https://www.expedia.co.uk/Charleston-Hotels-Market-Pavilion-Hotel.h910028.Hotel-Information) Charleston Historic District 9.4/10 Exceptional (1,013 reviews) "Gorgeous and wonderful staff and location. I will stay over and over again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda [](https://www.expedia.co.uk/Charleston-Hotels-Market-Pavilion-Hotel.h910028.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/b8d82b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (31 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £225 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42874/7a3da7fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/42900/42874/7f6af5ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42900/42874/41b54174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Room 11) | Premium bedding, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/50000/42900/42874/f93a1057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rhett House Inn [](https://www.expedia.co.uk/Beaufort-Hotels-Rhett-House-Inn.h42874.Hotel-Information) Downtown Beaufort 9.2/10 Wonderful (645 reviews) "The service was great! the blueberry pancakes were the best I've ever had!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia [](https://www.expedia.co.uk/Beaufort-Hotels-Rhett-House-Inn.h42874.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30®ionId=242&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Boutique-Hotel.0-0-d242-tBoutiqueHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Boutique-Hotel.0-0-d242-tBoutiqueHotel.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Beautiful spot with tons of unique details " [](https://expedia.co.uk/Charleston-Hotels-Emeline.h8890.Hotel-Information) ![Hilton Grand Vacations Club Ocean Enclave Myrtle Beach](https://images.trvl-media.com/lodging/34000000/33220000/33213200/33213151/d233caaf_y.jpg) ### Hilton Grand Vacations Club Ocean Enclave Myrtle Beach 10/10 Excellent "Very clean and peaceful " [](https://expedia.co.uk/Myrtle-Beach-Hotels-Ocean-Enclave-By-Hilton-Grand-Vacations.h33213151.Hotel-Information) ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Great old hotel in the heart of the city. Lots of shopping and restaurants. Valet parking was very handy and Uber was never more than 2 minutes from us. The staff were great and the Swamp Fox restaurant had delicious food and a wonderful server named Sylvie." [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Harborside at Charleston Harbor Resort and Marina](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/0212aa65_y.jpg) ### Harborside at Charleston Harbor Resort and Marina 10/10 Excellent "Very relaxed atmosphere, beautiful grounds, great views, just a great immersion into Charleston life." [](https://expedia.co.uk/Charleston-Hotels-Harborside-At-Charleston-Harbor-Resort-And-Marina.h67652.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Convenient and clean" [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Coral Beach Resort and Suites](https://images.trvl-media.com/lodging/1000000/40000/37100/37007/92701cca_y.jpg) ### Coral Beach Resort and Suites 10/10 Excellent "Nice place to stay. Quite a ways from the boardwalk but otherwise enjoyable!" [](https://expedia.co.uk/Myrtle-Beach-Hotels-Coral-Beach-Resort-Hotel-Suites.h37007.Hotel-Information) ![Holiday Inn Express Hilton Head Island by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3_y.jpg) ### Holiday Inn Express Hilton Head Island by IHG 10/10 Excellent "Great customer service beginning at check in" [](https://expedia.co.uk/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![Hyatt Place Charleston/Historic District](https://images.trvl-media.com/lodging/11000000/10520000/10519900/10519812/b130f925_y.jpg) ### Hyatt Place Charleston/Historic District 10/10 Excellent "Staff were friendly. I did make a note at checkout the 2nd floor where I was staying when you got off the elevator you were hit with a smell of mold like maybe they shampooed the carpets with a dirty solution…it was terrible and went the entire hallway. We had a fire alarm pulled at 2:00 am and they evacuated the entire hotel. That was a bit rough. " [](https://expedia.co.uk/Charleston-Hotels-Hyatt-Place-CharlestonHistoric-District.h10519812.Hotel-Information) ![Planters Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/c138e1de_y.jpg) ### Planters Inn 10/10 Excellent "Hotel very charming. Dinner was spectacular both in terms of menu, service and ambiance. Highly recommend " [](https://expedia.co.uk/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Arsenal Hill Hotels ](https://www.expedia.co.uk/Arsenal-Hill-Columbia-Hotels.0-n6346756-0.Travel-Guide-Filter-Hotels) - [Spa Hotels in Blythewood ](https://www.expedia.co.uk/Blythewood-Hotels-Spa-Hotels.0-0-d180657-tSpaHotels.Travel-Guide-Filter-Hotels) - [Cayce Hotels ](https://www.expedia.co.uk/Cayce-Hotels.d55624.Travel-Guide-Hotels) - [Adults Only Resorts & in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Adults-Only-Resorts.0-0-d764-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Budget-Hotels.0-0-d764-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Gay-Friendly-Hotel.0-0-d764-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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