Title: South Carolina Spa Hotels, United States of America: South Carolina Hotel Guide | Expedia.co.uk [South Carolina Travel Guide](https://expedia.co.uk/South-Carolina.dx242)[South Carolina Hotels](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Holiday Rentals in South Carolina](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations)[South Carolina Flights](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Hire](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Car-Hire-Destinations)[South Carolina Holidays](https://expedia.co.uk/South-Carolina.d242.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Spa Hotels in South Carolina - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Carolina Accommodation: Most Popular Cities to Stay ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/553000/553975-charleston-sc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Charleston [](https://expedia.co.uk/Charleston-Hotels-Spa-Hotels.0-0-d179997-tSpaHotels.Travel-Guide-Filter-Hotels) ![Greenville featuring a bridge, a city and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.co.uk/Greenville-Hotels-Spa-Hotels.0-0-d1388-tSpaHotels.Travel-Guide-Filter-Hotels) ![USS Yorktown showing aircraft](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/30000/30538-Uss-Yorktown.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Mount Pleasant [](https://expedia.co.uk/Mount-Pleasant-Hotels-Spa-Hotels.0-0-d8675-tSpaHotels.Travel-Guide-Filter-Hotels) ![Spartanburg showing farmland, a house and land animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63879-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Spartanburg [](https://expedia.co.uk/Spartanburg-Hotels-Spa-Hotels.0-0-d9787-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina Spa Hotels Tonight [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-23&endDate=2025-12-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-24&endDate=2025-12-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina hotels with a spa ![Couples treatment room(s), sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1110000/1105600/1105531/5ef82707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Bedroom (Montage Residence 1002) | Living area | Smart TV, DVD player](https://images.trvl-media.com/lodging/2000000/1110000/1105600/1105531/7357d132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/2000000/1110000/1105600/1105531/b62b7a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/2000000/1110000/1105600/1105531/b88d099f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montage Palmetto Bluff [](https://www.expedia.co.uk/Hilton-Head-Hotels-Montage-Palmetto-Bluff.h1105531.Hotel-Information) Palmetto Bluff 9.6/10 Exceptional (255) "Beautiful resort with much to do! Accommodations are beautiful and Excellent hospitality too." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine £354 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Hilton-Head-Hotels-Montage-Palmetto-Bluff.h1105531.Hotel-Information) ![Gift shop](https://images.trvl-media.com/lodging/23000000/22650000/22649900/22649862/7f333e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, lobby lounge, rooftop bar, Champagne bar](https://images.trvl-media.com/lodging/23000000/22650000/22649900/22649862/2b9bceba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/23000000/22650000/22649900/22649862/c2a62a2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, lobby lounge, rooftop bar, Champagne bar](https://images.trvl-media.com/lodging/23000000/22650000/22649900/22649862/e609c5f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bennett [](https://www.expedia.co.uk/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information) Charleston Historic District 9.6/10 Exceptional (980) "Absolutely loved the stay. We’ve stayed a few other times in the past and it never disappoints! If you want a luxury hotel right on King street you can’t do better! We will continue to come back. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald £327 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information) ![Couples treatment room(s), sauna, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/5eb9b6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/63d8939c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/8bc9a47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/9b424641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Charleston Place [](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) Charleston Historic District 9.6/10 Exceptional (1007) "Staff was great, room perfect and we had a lovely time in Charleston!😊" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janis £344 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/1000000/920000/913700/913618/1700c952.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/920000/913700/913618/cbc44c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Oceanfront (Brighton) | Living area | 50-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/920000/913700/913618/w3840h2556x0y0-3ac111ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 3 Bedrooms, Oceanfront (Margate) | View from room](https://images.trvl-media.com/lodging/1000000/920000/913700/913618/11bd4e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kingston Plantation Condos [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Kingston-Plantation-Condos.h913618.Hotel-Information) Myrtle Beach 7.8/10 Good (1004) "The resort is awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolyn £82 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Kingston-Plantation-Condos.h913618.Hotel-Information) ![Indoor pool, outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/1000000/994500/994467/59e256cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/994500/994467/4b6de3bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch TV with satellite channels, ping pong, books](https://images.trvl-media.com/lodging/1000000/1000000/994500/994467/472b7897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/1000000/994500/994467/96ac0035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott's OceanWatch at Grande Dunes [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Marriotts-OceanWatch-At-Grande-Dunes.h994467.Hotel-Information) Myrtle Beach 9.4/10 Exceptional (473) "kitchen, washer dryer, many pools, close to beach, clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daian £110 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Marriotts-OceanWatch-At-Grande-Dunes.h994467.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/acf3332d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/89af43a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/72c5c1f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/bde1e3a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Myrtle-Beach-N-Kings-Hwy.h6849.Hotel-Information) Myrtle Beach 8.2/10 Very good (2481) "Yes good stay staff super nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber £53 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Myrtle-Beach-N-Kings-Hwy.h6849.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9990000/9988100/9988009/6b9e38c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9990000/9988100/9988009/0a22ba84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/10000000/9990000/9988100/9988009/5d90b99f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/10000000/9990000/9988100/9988009/d44e39b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Charleston/Historic District [](https://www.expedia.co.uk/Charleston-Hotels-Hyatt-House-CharlestonHistoric-District.h9988009.Hotel-Information) Downtown Charleston 8.6/10 Excellent (1004) "Clean room, close to restaurant and bars, friendly valet parking service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernanda £128 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Charleston-Hotels-Hyatt-House-CharlestonHistoric-District.h9988009.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b840578e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Double Beds, Non Smoking | Living area | 37-inch flat-screen TV with cable channels, TV, pay films](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/f2d60448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Greenville Golf Resort & Conference Center [](https://www.expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Greenville 9.0/10 Wonderful (1030) "Great room, staff and location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neil £80 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Couples treatment room(s), hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/9ca2c42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/0212aa65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/9b68c985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/w495h217x0y6-f026e9f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harborside at Charleston Harbor Resort and Marina [](https://www.expedia.co.uk/Charleston-Hotels-Harborside-At-Charleston-Harbor-Resort-And-Marina.h67652.Hotel-Information) Mount Pleasant 8.6/10 Excellent (2024) "close to things to do, water taxi, hotel shuttle" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) vincent £92 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Charleston-Hotels-Harborside-At-Charleston-Harbor-Resort-And-Marina.h67652.Hotel-Information) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/0d84d9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/4bf90c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (631) "Beautiful location, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £149 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-06&endDate=2026-01-07®ionId=242&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Spa-Hotels.0-0-d242-tSpaHotels.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Spa-Hotels.0-0-d242-tSpaHotels.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Francis Marion hotel is a beautiful hotel in a great location! We had the best breakfast with the happiest and most hospitable server, Sylvie. " [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Hilton Grand Vacations Club Ocean Enclave Myrtle Beach](https://images.trvl-media.com/lodging/34000000/33220000/33213200/33213151/d233caaf_y.jpg) ### Hilton Grand Vacations Club Ocean Enclave Myrtle Beach 10/10 Excellent "Beautiful resort, rooms were comfortable and clean. Great vacation spot." [](https://expedia.co.uk/Myrtle-Beach-Hotels-Ocean-Enclave-By-Hilton-Grand-Vacations.h33213151.Hotel-Information) ![Homewood Suites by Hilton Myrtle Beach Oceanfront](https://images.trvl-media.com/lodging/24000000/23500000/23491200/23491112/7c222716_y.jpg) ### Homewood Suites by Hilton Myrtle Beach Oceanfront 10/10 Excellent "View and breakfast buffet amazing " [](https://expedia.co.uk/Myrtle-Beach-Hotels-South-Bay-Inn-And-Suites.h23491112.Hotel-Information) ![Anderson Ocean Club and Spa by Oceana Resorts](https://images.trvl-media.com/lodging/2000000/1780000/1773500/1773482/c3e5f34d_y.jpg) ### Anderson Ocean Club and Spa by Oceana Resorts 10/10 Excellent "The room was awesome, it was a suite with plenty of room and a good ocean vier. Bed was comfortable, nice big TV, fridge, washer, dryer and kitchenette. Perfectly furnished." [](https://expedia.co.uk/Myrtle-Beach-Hotels-Anderson-Ocean-Club-And-Spa-By-Oceana-Resorts.h1773482.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Awesome and super clean " [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Planters Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/c138e1de_y.jpg) ### Planters Inn 10/10 Excellent "Staff was great, rooms were clean but a little outdated." [](https://expedia.co.uk/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ![Hyatt Place Charleston/Historic District](https://images.trvl-media.com/lodging/11000000/10520000/10519900/10519812/b130f925_y.jpg) ### Hyatt Place Charleston/Historic District 10/10 Excellent "Very friendly staff and good overall but towells too small and lack of parking a real problem " [](https://expedia.co.uk/Charleston-Hotels-Hyatt-Place-CharlestonHistoric-District.h10519812.Hotel-Information) ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Excellent property! Great location and the restaurant is fantastic. " [](https://expedia.co.uk/Charleston-Hotels-Emeline.h8890.Hotel-Information) ![Dunes Village Resort](https://images.trvl-media.com/lodging/1000000/990000/983000/982925/a147d3c1_y.jpg) ### Dunes Village Resort 10/10 Excellent "Good " [](https://expedia.co.uk/Myrtle-Beach-Hotels-Dunes-Village-Resort.h982925.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Arsenal Hill Hotels ](https://www.expedia.co.uk/Arsenal-Hill-Columbia-Hotels.0-n6346756-0.Travel-Guide-Filter-Hotels) - [Spa Hotels in Blythewood ](https://www.expedia.co.uk/Blythewood-Hotels-Spa-Hotels.0-0-d180657-tSpaHotels.Travel-Guide-Filter-Hotels) - [Cayce Hotels ](https://www.expedia.co.uk/Cayce-Hotels.d55624.Travel-Guide-Hotels) - [Adults Only Resorts & in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Adults-Only-Resorts.0-0-d764-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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