Title: South Carolina Gay-Friendly Hotels, United States of America: South Carolina Hotel Guide | Expedia.co.uk [South Carolina Travel Guide](https://expedia.co.uk/South-Carolina.dx242)[South Carolina Hotels](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Holiday Rentals in South Carolina](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations)[South Carolina Flights](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Hire](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Car-Hire-Destinations)[South Carolina Holidays](https://expedia.co.uk/South-Carolina.d242.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Carolina Accommodation: Most Popular Cities to Stay ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/553000/553975-charleston-sc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Charleston [](https://expedia.co.uk/Charleston-Hotels-Gay-Friendly-Hotel.0-0-d179997-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/494000/494078-myrtle-beach.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Myrtle Beach [](https://expedia.co.uk/Myrtle-Beach-Hotels-Gay-Friendly-Hotel.0-0-d601685-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/184000/184006-State-House.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Columbia [](https://expedia.co.uk/Columbia-Hotels-Gay-Friendly-Hotel.0-0-d764-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Greenville featuring a bridge, a city and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.co.uk/Greenville-Hotels-Gay-Friendly-Hotel.0-0-d1388-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/493000/493363-coastal-south-carolina.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### North Myrtle Beach [](https://expedia.co.uk/North-Myrtle-Beach-Hotels-Gay-Friendly-Hotel.0-0-d8929-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![USS Yorktown showing aircraft](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/30000/30538-Uss-Yorktown.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Mount Pleasant [](https://expedia.co.uk/Mount-Pleasant-Hotels-Gay-Friendly-Hotel.0-0-d8675-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Spartanburg showing farmland, a house and land animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63879-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Spartanburg [](https://expedia.co.uk/Spartanburg-Hotels-Gay-Friendly-Hotel.0-0-d9787-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/02bc21c256f396c5f15b8a28c58632c0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### North Charleston [](https://expedia.co.uk/North-Charleston-Hotels-Gay-Friendly-Hotel.0-0-d9156-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina Gay-Friendly Hotels Tonight [14 Jan - 15 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-14&endDate=2026-01-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [15 Jan - 16 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ## Our top choices for South Carolina LGBT-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/8bc9a47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/bd482489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/63d8939c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/9b424641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Charleston Place [](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) Charleston Historic District 9.6/10 Exceptional (1,001 reviews) "Very nice , helpful and friendly staff, great location. Great ambiance for family vacation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nazanin £345 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30®ionId=242&adults=2&travelerType=lgbtq_welcoming&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Gay-Friendly-Hotel.0-0-d242-tGayFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Gay-Friendly-Hotel.0-0-d242-tGayFriendlyHotel.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Great old hotel in the heart of the city. Lots of shopping and restaurants. Valet parking was very handy and Uber was never more than 2 minutes from us. The staff were great and the Swamp Fox restaurant had delicious food and a wonderful server named Sylvie." [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Harborside at Charleston Harbor Resort and Marina](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/0212aa65_y.jpg) ### Harborside at Charleston Harbor Resort and Marina 10/10 Excellent "Very relaxed atmosphere, beautiful grounds, great views, just a great immersion into Charleston life." [](https://expedia.co.uk/Charleston-Hotels-Harborside-At-Charleston-Harbor-Resort-And-Marina.h67652.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Convenient and clean" [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Coral Beach Resort and Suites](https://images.trvl-media.com/lodging/1000000/40000/37100/37007/92701cca_y.jpg) ### Coral Beach Resort and Suites 10/10 Excellent "Nice place to stay. Quite a ways from the boardwalk but otherwise enjoyable!" [](https://expedia.co.uk/Myrtle-Beach-Hotels-Coral-Beach-Resort-Hotel-Suites.h37007.Hotel-Information) ![Holiday Inn Express Hilton Head Island by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3_y.jpg) ### Holiday Inn Express Hilton Head Island by IHG 10/10 Excellent "Great customer service beginning at check in" [](https://expedia.co.uk/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![Hyatt Place Charleston/Historic District](https://images.trvl-media.com/lodging/11000000/10520000/10519900/10519812/b130f925_y.jpg) ### Hyatt Place Charleston/Historic District 10/10 Excellent "Staff were friendly. I did make a note at checkout the 2nd floor where I was staying when you got off the elevator you were hit with a smell of mold like maybe they shampooed the carpets with a dirty solution…it was terrible and went the entire hallway. We had a fire alarm pulled at 2:00 am and they evacuated the entire hotel. That was a bit rough. " [](https://expedia.co.uk/Charleston-Hotels-Hyatt-Place-CharlestonHistoric-District.h10519812.Hotel-Information) ![Planters Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/c138e1de_y.jpg) ### Planters Inn 10/10 Excellent "Hotel very charming. Dinner was spectacular both in terms of menu, service and ambiance. Highly recommend " [](https://expedia.co.uk/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Nice clean hotel. It was convenient to have complimentary Nespresso coffee and fruits on each floor. The room service was taking care about the bed and the rest of the room every day. The location is very convenient." [](https://expedia.co.uk/Charleston-Hotels-Emeline.h8890.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/bde1e3a3_y.jpg) ### La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy 10/10 Excellent "Great location, very clean and customer service was excellent ⭐️⭐️⭐️⭐️⭐️" [](https://expedia.co.uk/Myrtle-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Myrtle-Beach-N-Kings-Hwy.h6849.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Arsenal Hill Hotels ](https://www.expedia.co.uk/Arsenal-Hill-Columbia-Hotels.0-n6346756-0.Travel-Guide-Filter-Hotels) - [Spa Hotels in Blythewood ](https://www.expedia.co.uk/Blythewood-Hotels-Spa-Hotels.0-0-d180657-tSpaHotels.Travel-Guide-Filter-Hotels) - [Cayce Hotels ](https://www.expedia.co.uk/Cayce-Hotels.d55624.Travel-Guide-Hotels) - 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