Title: South Carolina Pet-Friendly Hotels, United States of America: South Carolina Hotel Guide | Expedia.co.uk [South Carolina Travel Guide](https://expedia.co.uk/South-Carolina.dx242)[South Carolina Hotels](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Holiday Rentals in South Carolina](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations)[South Carolina Flights](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Hire](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Car-Hire-Destinations)[South Carolina Holidays](https://expedia.co.uk/South-Carolina.d242.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Pet-Friendly Hotels in South Carolina - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Carolina Accommodation: Most Popular Cities to Stay ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/553000/553975-charleston-sc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Charleston [](https://expedia.co.uk/Charleston-Hotels-Pet-Friendly-Hotel.0-0-d179997-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) ![Greenville featuring a bridge, a city and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.co.uk/Greenville-Hotels-Pet-Friendly-Hotel.0-0-d1388-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) ![Spartanburg showing farmland, a house and land animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63879-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Spartanburg [](https://expedia.co.uk/Spartanburg-Hotels-Pet-Friendly-Hotel.0-0-d9787-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina Pet-Friendly Hotels Tonight [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-19&endDate=2025-12-20&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-20&endDate=2025-12-21&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina pet-friendly hotels ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/258371f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/024086db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1252) "Newly remodeled rooms. Very clean. Very friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa £65 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/5e9a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown [](https://www.expedia.co.uk/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Greenville Downtown 9.0/10 Wonderful (1003) "Always a great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £107 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1416) "Very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramil £66 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/5762bff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/5d01eb22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/18d38dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/770a2abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Walterboro, SC [](https://www.expedia.co.uk/Walterboro-Hotels-Motel-6-Walterboro.h2311717.Hotel-Information) Walterboro 8.2/10 Very good (1416) "Room was spotless and the staff was excellent. Would love to stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina £47 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Walterboro-Hotels-Motel-6-Walterboro.h2311717.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/8f9ec695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Balcony, Ocean View | Private kitchen | Microwave, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/7ead828c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen | Microwave, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/f27a633a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/023eb012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Darlington Inn [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Darlington-Inn.h9816023.Hotel-Information) Downtown Myrtle Beach 9.2/10 Wonderful (1001) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £60 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Darlington-Inn.h9816023.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/5abcf1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/bf29fa04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) Florence 9.4/10 Exceptional (927) "Friendly staff, great breakfast, beautiful ammenities!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandi £105 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/16951e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/714de801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/581a55d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/e98971cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Point South [](https://www.expedia.co.uk/Beaufort-Hotels-Best-Western-Point-South.h24264.Hotel-Information) Yemassee 8.0/10 Very good (1001) "the room was very clean. nice quiet place to sleep. the grounds were well maintained. great bargain for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonia £68 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Beaufort-Hotels-Best-Western-Point-South.h24264.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/114dbfdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/396bbda9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/efbb37db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/15c4ab94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vancouver Motel [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Vancouver-Motel.h1925221.Hotel-Information) Myrtle Beach 8.2/10 Very good (1001) "The beach was AMAZING " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet £35 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Vancouver-Motel.h1925221.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/e6902cd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11093b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (633) "Room was clean and the staff were good. Overall I would recommend this hotel!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) George £55 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/c105915a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/824b9567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/38be55ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Florence 8.0/10 Very good (1671) "Th room was nice comfortable breakfast was good and the people were very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George £75 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=242&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Pet-Friendly-Hotel.0-0-d242-tPetFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Pet-Friendly-Hotel.0-0-d242-tPetFriendlyHotel.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![Hyatt Place Charleston/Historic District](https://images.trvl-media.com/lodging/11000000/10520000/10519900/10519812/b130f925_y.jpg) ### Hyatt Place Charleston/Historic District 10/10 Excellent "Very friendly staff and good overall but towells too small and lack of parking a real problem " [](https://expedia.co.uk/Charleston-Hotels-Hyatt-Place-CharlestonHistoric-District.h10519812.Hotel-Information) ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Excellent property! Great location and the restaurant is fantastic. " [](https://expedia.co.uk/Charleston-Hotels-Emeline.h8890.Hotel-Information) ![Dunes Village Resort](https://images.trvl-media.com/lodging/1000000/990000/983000/982925/a147d3c1_y.jpg) ### Dunes Village Resort 10/10 Excellent "Good " [](https://expedia.co.uk/Myrtle-Beach-Hotels-Dunes-Village-Resort.h982925.Hotel-Information) ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Check in was seamless and the rooms were beautiful. Showers had great pressure and the staff was very professional and helpful" [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Hilton Grand Vacations Club Ocean Enclave Myrtle Beach](https://images.trvl-media.com/lodging/34000000/33220000/33213200/33213151/d233caaf_y.jpg) ### Hilton Grand Vacations Club Ocean Enclave Myrtle Beach 10/10 Excellent "Staff and amenities." [](https://expedia.co.uk/Myrtle-Beach-Hotels-Ocean-Enclave-By-Hilton-Grand-Vacations.h33213151.Hotel-Information) ![Anderson Ocean Club and Spa by Oceana Resorts](https://images.trvl-media.com/lodging/2000000/1780000/1773500/1773482/c3e5f34d_y.jpg) ### Anderson Ocean Club and Spa by Oceana Resorts 10/10 Excellent "Room was clean and staff was great." [](https://expedia.co.uk/Myrtle-Beach-Hotels-Anderson-Ocean-Club-And-Spa-By-Oceana-Resorts.h1773482.Hotel-Information) ![The Ryder Hotel](https://images.trvl-media.com/lodging/1000000/10000/4600/4544/722c7929_y.jpg) ### The Ryder Hotel 10/10 Excellent "Great design " [](https://expedia.co.uk/Charleston-Hotels-The-Ryder-Hotel.h4544.Hotel-Information) ![Homewood Suites by Hilton Myrtle Beach Oceanfront](https://images.trvl-media.com/lodging/24000000/23500000/23491200/23491112/7c222716_y.jpg) ### Homewood Suites by Hilton Myrtle Beach Oceanfront 10/10 Excellent "Stayed one night. Comfortable bed and room. Food was ok, drinks good. Great stay. " [](https://expedia.co.uk/Myrtle-Beach-Hotels-South-Bay-Inn-And-Suites.h23491112.Hotel-Information) ![Sands Ocean Club Resort](https://images.trvl-media.com/lodging/1000000/30000/22600/22518/ec0e33cc_y.jpg) ### Sands Ocean Club Resort 10/10 Excellent "The room had a wonderful view of the beach. The staff were all outstanding and the total experience was incredible." 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