Title: South Carolina Pet-Friendly Hotels, United States of America: South Carolina Hotel Guide | Expedia.co.uk [South Carolina Travel Guide](https://expedia.co.uk/South-Carolina.dx242)[South Carolina Hotels](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Holiday Rentals in South Carolina](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations)[South Carolina Flights](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Hire](https://expedia.co.uk/Destinations-In-South-Carolina.d242.Car-Hire-Destinations)[South Carolina Holidays](https://expedia.co.uk/South-Carolina.d242.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Carolina Accommodation: Most Popular Cities to Stay ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/553000/553975-charleston-sc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Charleston [](https://expedia.co.uk/Charleston-Hotels-Pet-Friendly-Hotel.0-0-d179997-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) ![Greenville featuring a bridge, a city and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.co.uk/Greenville-Hotels-Pet-Friendly-Hotel.0-0-d1388-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) ![Spartanburg showing farmland, a house and land animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63879-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Spartanburg [](https://expedia.co.uk/Spartanburg-Hotels-Pet-Friendly-Hotel.0-0-d9787-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina Pet-Friendly Hotels Tonight [3 Feb - 4 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-02-03&endDate=2026-02-04&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Feb - 5 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-02-04&endDate=2026-02-05&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-02-06&endDate=2026-02-08&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=242&startDate=2026-02-13&endDate=2026-02-15&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina pet-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/1c348a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,259 reviews) "I have to say it was all especially the staff very welcoming to us when we came when I came in room is very well clean. I will definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita £69 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/e91d37ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/3665dfba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown [](https://www.expedia.co.uk/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1,001 reviews) "Room was very clean, the staff was great and the location was perfect!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike £109 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,425 reviews) "Always a great stay. Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela £61 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/8b72d0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/d93feb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/fb34eb7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2320000/2311800/2311717/032164c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Walterboro, SC [](https://www.expedia.co.uk/Walterboro-Hotels-Motel-6-Walterboro.h2311717.Hotel-Information) Walterboro 8.2/10 Very good (1,449 reviews) "room was clean,easy access from highway,truck parking,friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald £49 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Walterboro-Hotels-Motel-6-Walterboro.h2311717.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/8f9ec695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/6576bf80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area | 32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/4e0c81e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9820000/9816100/9816023/ec472217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Darlington Inn [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Darlington-Inn.h9816023.Hotel-Information) Downtown Myrtle Beach 9.2/10 Wonderful (1,000 reviews) "Very clean and very quiet.A nice little motel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George £58 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Darlington-Inn.h9816023.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Tempur-Pedic beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/861e9f4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/042032ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) Florence 9.4/10 Exceptional (955 reviews) "Room clean, bed good, breakfast good choices, front desk excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mona £110 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/975ff0d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/714de801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/2ac82115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/ab1fd891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Point South [](https://www.expedia.co.uk/Beaufort-Hotels-Best-Western-Point-South.h24264.Hotel-Information) Yemassee 8.2/10 Very good (1,000 reviews) "Incredibly helpful staff, also a great place to stay if you have a pet!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David [](https://www.expedia.co.uk/Beaufort-Hotels-Best-Western-Point-South.h24264.Hotel-Information) ![On the beach](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/b0ea3509.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/4b62d37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/396bbda9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/2000000/1930000/1925300/1925221/3e01206f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vancouver Motel [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Vancouver-Motel.h1925221.Hotel-Information) Myrtle Beach 8.2/10 Very good (1,003 reviews) "Very relaxing stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy £34 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Myrtle-Beach-Hotels-Vancouver-Motel.h1925221.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11ccce69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11093b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (651 reviews) "Breakfast was an overstatement!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicki £61 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Deluxe Family Room) | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/9ce36c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f732d5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/867e6dd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Florence 8.0/10 Very good (1,672 reviews) "Clean rooms, friendly staff, great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna £82 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-17&endDate=2026-02-18®ionId=242&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Pet-Friendly-Hotel.0-0-d242-tPetFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-Pet-Friendly-Hotel.0-0-d242-tPetFriendlyHotel.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![Hilton Grand Vacations Club Ocean Enclave Myrtle Beach](https://images.trvl-media.com/lodging/34000000/33220000/33213200/33213151/d233caaf_y.jpg) ### Hilton Grand Vacations Club Ocean Enclave Myrtle Beach 10/10 Excellent "The room was excellent! If I had to critique anything it would be the water pressure inside the shower it was pretty low. But, other than that 10/10\. " [](https://expedia.co.uk/Myrtle-Beach-Hotels-Ocean-Enclave-By-Hilton-Grand-Vacations.h33213151.Hotel-Information) ![Omni Hilton Head Oceanfront Resort](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/c13a70d7_y.jpg) ### Omni Hilton Head Oceanfront Resort 10/10 Excellent "Room was clean quiet and large. The staff was very courteous. Would stay again. " [](https://expedia.co.uk/Hilton-Head-Hotels-Omni-Hilton-Head-Oceanfront-Resort.h14690.Hotel-Information) ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Lovely hotel in a great location. Friendly, helpful staff and lots of thoughtful touches." [](https://expedia.co.uk/Charleston-Hotels-Emeline.h8890.Hotel-Information) ![Sonesta Resort Hilton Head Island](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/220ad345_y.jpg) ### Sonesta Resort Hilton Head Island 10/10 Excellent "Updated since last time I was there , upgraded my stay which was nice . Few people as was off season which was very nice " [](https://expedia.co.uk/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) ![Anderson Ocean Club and Spa by Oceana Resorts](https://images.trvl-media.com/lodging/2000000/1780000/1773500/1773482/c3e5f34d_y.jpg) ### Anderson Ocean Club and Spa by Oceana Resorts 10/10 Excellent "Clean rooms, full equipped and quite." [](https://expedia.co.uk/Myrtle-Beach-Hotels-Anderson-Ocean-Club-And-Spa-By-Oceana-Resorts.h1773482.Hotel-Information) ![Sands Ocean Club Resort](https://images.trvl-media.com/lodging/1000000/30000/22600/22518/ec0e33cc_y.jpg) ### Sands Ocean Club Resort 10/10 Excellent "Room was very clean. Staff quick and positive." [](https://expedia.co.uk/Myrtle-Beach-Hotels-Sands-Ocean-Club-Resort.h22518.Hotel-Information) ![The Beach Club at Charleston Harbor Resort and Marina](https://images.trvl-media.com/lodging/14000000/13200000/13199200/13199113/c2fc6e8d_y.jpg) ### The Beach Club at Charleston Harbor Resort and Marina 10/10 Excellent "Room was excellent, except for cold shower. I have never stayed in any resort or hotel where the shower would not get warm no matter how long you left it on. Otherwise , room was very nice. " [](https://expedia.co.uk/Charleston-Hotels-The-Beach-Club-At-Charleston-Harbor-Resort-And-Marina.h13199113.Hotel-Information) ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Great location. Beautiful, clean, spacious room. Charming and comfortable lobby. We will be back. " [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy](https://images.trvl-media.com/lodging/1000000/10000/6900/6849/bde1e3a3_y.jpg) ### La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy 10/10 Excellent "Great check in. Very quiet. Clean room " [](https://expedia.co.uk/Myrtle-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Myrtle-Beach-N-Kings-Hwy.h6849.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Arsenal Hill Hotels ](https://www.expedia.co.uk/Arsenal-Hill-Columbia-Hotels.0-n6346756-0.Travel-Guide-Filter-Hotels) - [Spa Hotels in Blythewood ](https://www.expedia.co.uk/Blythewood-Hotels-Spa-Hotels.0-0-d180657-tSpaHotels.Travel-Guide-Filter-Hotels) - [Cayce Hotels ](https://www.expedia.co.uk/Cayce-Hotels.d55624.Travel-Guide-Hotels) - [Adults Only Resorts & in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Adults-Only-Resorts.0-0-d764-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Budget-Hotels.0-0-d764-tBudgetHotels.Travel-Guide-Filter-Hotels) - 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