Title: Holiday Rentals South Carolina Midlands from £122: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [South Carolina Midlands Travel Guide](https://expedia.co.uk/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Flights to South Carolina Midlands](https://expedia.co.uk/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.co.uk/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Carolina-Midlands.d6057938.Car-Hire-Guide)[South Carolina Midlands Holidays](https://expedia.co.uk/South-Carolina-Midlands.d6057938.Holidays-City-Breaks) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/183000/183997-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in South Carolina Midlands ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-10-12&endDate=2025-10-13&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-10-13&endDate=2025-10-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-10-17&endDate=2025-10-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-10-24&endDate=2025-10-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Holiday Rentals in South Carolina Midlands ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/b733a543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/be58ae40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/917b8b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/e9758649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Columbia-Irmo Harbison Irmo 8.6/10 Excellent (314) "This property was a great stay with our fur babies. I love the spacious room and of course being a pet friendly property. " [](https://www.expedia.co.uk/Irmo-Hotels-StayAPT-Suites-Columbia-Irmo-Harbison.h71943321.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/afc287a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/376ea7b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/3b341f15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft 007 Ft. on HGTV | Terrace/patio](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/0841e785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hangar Lofts Hotel Rosewood 8.6/10 Excellent (65) "Property was a very pleasant surprise. Only thing I wish I we had was a secondary safety look on the door. " £122 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Columbia-Hotels-The-Hangar-Lofts-Hotel.h45147909.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/w7294h4496x8y0-e7e0c635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/d6e5ecdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/2b2bb3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/5ac04ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Rock Hill Rock Hill 8.4/10 Very good (186) "This was such an amazing stay ! Very peaceful atmosphere and great employees!" [](https://www.expedia.co.uk/Rock-Hill-Hotels-StayAPT-Suites-Rock-Hill.h71945688.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/2a2ac9f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/a0cb5199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/802a58f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/3b88798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Last Resort at Martins Landing Hollands Landing 9.8/10 Exceptional (30) "This little cabin was perfect! The size was great and the location was really nice! It was in walking distance to the water and 2 great restaurants! " £147 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Prosperity-Hotels-The-Last-Resort-At-Martins-Landing.h79209711.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/d11c2084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/8cdaa2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, video library](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/db2f6213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/d8d48774.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Replica home from Jack Nicholson movie - 'Something's Gotta Give' Chapin 9.8/10 Exceptional (139) "We had a relaxing wonderful time..the owner was very nice and helpful ..always responded promptly." [](https://www.expedia.co.uk/Chapin-Hotels-Replica-Home-From-Jack-Nicholson-Movie-Somethings-Gotta-Give.h24256959.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/87150793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel cot, WiFi](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/8e7a6fa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/6f910332.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/bd8fa2a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 Bdrm Condo w/in 10 min from USC, Downtown Columbia, Ft Jackson, VA hospital Rosewood 9.4/10 Exceptional (46) "It was cozy apartment great for a weekend getaway. My daughter loved the rooms and said the beds were super comfy." [](https://www.expedia.co.uk/Columbia-Hotels-2-Bdrm-Condo-Win-10-Min-From-USC.h100706194.Hotel-Information) ![Beach nearby, sun-loungers, beach towels](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/3fe1338e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/09ba0e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/a1639ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/01ea4499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Exclusive Peninsula Retreat on Lake Murray – Beach, Fire Pit & Stunning Sunsets Chapin 10/10 Exceptional (56) "We had a wonderful time. We definitely recommend this lake house. Absolutely beautiful " [](https://www.expedia.co.uk/Chapin-Hotels-Mind-Blowing-Sunsets-On-A-Gated-Peninsula-Property-With-A-White-Sand-Beach.h76317327.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/w1024h680x0y3-9269f16b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, cookware/dishes/utensils](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/50215f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/b59bdaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, cookware/dishes/utensils](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/eac9cc87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NoMa Green House Columbia 9.8/10 Exceptional (67) "Suited our needs with 3 adults in the party. Quite neighborhood. Lovely front porch.Comfortable beds and large rooms." £188 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Columbia-Hotels-NoMa-Green-House.h91039871.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/56893853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/d9f603fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/4a367a68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/d02f516e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Romantic bungalow on Lake Murray w/cold plunge/hot tub/sauna, gym & dock gazebo Lexington 10/10 Exceptional (12) "Took the Mrs fishing for a weekend away. Kent was very professional and made all accommodations perfect. Would definitely recommend and look forward to coming back. " [](https://www.expedia.co.uk/Lexington-Hotels-Romantic-Bungalow-On-Lake-Murray-Wcold-Plungehot-Tubsauna.h112562606.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103650000/103645300/103645220/e62938f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103650000/103645300/103645220/c590a240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103650000/103645300/103645220/w1190h802x0y0-ae8ac4cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103650000/103645300/103645220/w1192h808x0y5-23b83bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 3 Bedroom Townhome West Columbia 9.2/10 Wonderful (11) "We enjoyed our stay! Easy to navigate to and from restaurants and I-26! Very safe feeling little neighborhood too!" [](https://www.expedia.co.uk/West-Columbia-Hotels-Cozy-Townhome.h103645220.Hotel-Information) ![TV, fireplace, DVD player, table football](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/da60aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, table football](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/55278e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/c06e2569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/360b0a95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful 4 bedroom Lakehouse on a deep water cove on Lake Greenwood. Greenwood 10/10 Exceptional (191) "Loved this house! Owners were super responsive ! Would definitely recommend !" [](https://www.expedia.co.uk/Greenwood-Hotels-Beautiful-4-Bedroom-Lakehouse-On-A-Deep-Water-Cove-On-Lake-Greenwood.h22537351.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/17d2f4e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/3622349b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/d97d64ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Vacation Resorts Lake Marion Santee 9.2/10 Wonderful (20) "Friendly staff. Excellent accomodations. Peaceful and beautiful vacation." [](https://www.expedia.co.uk/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/109000000/108480000/108475900/108475851/9ca22f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108480000/108475900/108475851/3fb8a374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/109000000/108480000/108475900/108475851/3e745e7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/109000000/108480000/108475900/108475851/fd14fd8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quintessential 2-bedroom bungalow in the heart of Shandon in Columbia, SC. Downtown Columbia 10/10 Exceptional (34) "Cozy, clean, cute, beautiful property, comfy beds, excellent AC, and comfortable beds, the owners have thought of every amenity you might need! " [](https://www.expedia.co.uk/Columbia-Hotels-Quintessential-2-Bedroom-Bungalow-In-The-Heart-Of-Shandon-In-Columbia.h108475851.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/54575a7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/2ab091e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/bb62c643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/00fad188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quant Downtown Columbia Apartment Downtown Columbia 10/10 Exceptional (2) "Nice stay in center of five points close yo everything " £184 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/Columbia-Hotels-Quant-Downtown-Columbia-Apartment.h103458981.Hotel-Information) ![Smart TV, offices](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/339c1207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/79beb629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/10896652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! Santee 10/10 Exceptional (36) "Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! " £245 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/b1fcd805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/845b6468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/1c0b7271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/7ecb4f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam! Lexington 9.8/10 Exceptional (134) "Great stay, every thing was easy, clean and as advertised! We would stay here again!" £280 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Columbia-Hotels-Lake-Murray-Paradise-Lake-Front-Upstairs-Home-W-Peninsula-Lake-Views.h26925650.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/84000000/83260000/83256600/83256529/b5bbad4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83260000/83256600/83256529/c3f4c891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/84000000/83260000/83256600/83256529/df7cfe08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/84000000/83260000/83256600/83256529/e32159d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home away from home Rock Hill 9.8/10 Exceptional (104) "Stay was wonderful we really enjoy it. " [](https://www.expedia.co.uk/Rock-Hill-Hotels-Home-Away-From-Home.h83256529.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/67000000/66790000/66785000/66784919/54555414.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66790000/66785000/66784919/f3a86c30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/67000000/66790000/66785000/66784919/b96e0315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66790000/66785000/66784919/c8d01aa4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carriage House Villa and gardens in downtown historic Lexington SC Lexington 9.8/10 Exceptional (28) "Everything was great" [](https://www.expedia.co.uk/Lexington-Hotels-Carriage-House-Villa-And-Gardens-In-Downtown-Historic-Lexington-SC.h66784919.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/b7da2b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/683c7a80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/c87ec78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/4b7cb62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy Manning 9.8/10 Exceptional (90) "Perfect for a big family. Loved the house and the location. Beautiful lake. A very happy stay. " [](https://www.expedia.co.uk/Manning-Hotels-The-Big-Red-House.h89325563.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/c4bbcdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/73a3c768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/4d4ed2d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/c417e2ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunsets on Lake Marion Santee 9.4/10 Exceptional (13) "Great place to stay. " [](https://www.expedia.co.uk/Santee-Hotels-Sunsets-On-Lake-Marion.h107294387.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6057938&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Holiday-Rentals.d6057938.Travel-Guide-HolidayRentals)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Holiday-Rentals.d6057938.Travel-Guide-HolidayRentals) ## Top South Carolina Midlands Hotel Reviews ![Comfort Inn & Suites](//images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites 10/10 Excellent "Just great " [](https://expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](//images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "Room was clean and it was perfect for a nights sleep while traveling. " [](https://expedia.co.uk/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "It is a good clean place to sleep. Staff is nice" [](https://expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Tru By Hilton Columbia Downtown](//images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "My Wife and I enjoyed our stay at Tru by Hilton Columbia Downtown. We booked from Saturday to Monday and the hotel was fully booked. The price was very reasonable compared to the value you receive. Comfortable feel and modern property. The staff is extremely friendly. We had the pleasure of checking in with Lillie at the reception desk. The general manager sent me a message prior to our check in date, which I appreciated. We received messages from the Hotel staff asking how everything was going throughout our stay. The room was immaculate, the only thing I should have requested was a bigger comforter for the bed, lol. The proximity to Colonial life arena is a big reason why we choose this hotel. We took an uber to the arena Saturday night and it was only $10, the evening was beautiful and we decided to walk back to the hotel after the Maxwell concert. It was about a 20 minute leisurely walk. My Wife and I felt safe walking back, we were amongst a crowd of concert goers at first which fizzled down and then we realized we were amongst a bunch of USC students out enjoying their Saturday night. lol! Great night in Columbia and looking forward to our next stay at Tru Downtown Columbia. Close to different shops and restaurants, close to the Zoo and Botanical garden. Officially designated our Hotel of choice when we’re in town. Thank you!!" [](https://expedia.co.uk/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Marriott Columbia](//images.trvl-media.com/lodging/1000000/20000/17400/17353/4bcf0c43_y.jpg) ### Marriott Columbia 10/10 Excellent "I enjoy your everything " [](https://expedia.co.uk/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information) ![Graduate by Hilton Columbia SC](//images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Nice" [](https://expedia.co.uk/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](//images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Excellent 👍👍" [](https://expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia at Harbison, SC](//images.trvl-media.com/lodging/4000000/3540000/3531500/3531475/df25b656_y.jpg) ### Country Inn & Suites by Radisson, Columbia at Harbison, SC 10/10 Excellent "Great!" [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h3531475.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, SC](//images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "The unique part are the front staff i forgot they names the lady and the gentleman very nice and professional the best" [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ## Find out more about South Carolina Midlands **Everything you need to know about** **South Carolina Midlands** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the South Carolina Midlands holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South Carolina Midlands holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **South Carolina Midlands holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in South Carolina Midlands. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A South Carolina Midlands holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of South Carolina Midlands holiday rentals we have selected for you start as low as £122 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on South Carolina Midlands rentals** At Expedia, we put the best South Carolina Midlands holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top South Carolina Midlands rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South Carolina Midlands holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South Carolina Midlands. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in South Carolina Midlands ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - 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