Title: Hotels in Panacea, FL - Best Panacea Hotels from £58 - Fully Refundable Options - Expedia.co.uk [Panacea Travel Guide](https://expedia.co.uk/Panacea.dx3000431554)[Holiday Rentals in Panacea](https://expedia.co.uk/Panacea-Holiday-Rentals.d3000431554.Travel-Guide-HolidayRentals)[Panacea Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panacea.d3000431554.Car-Hire-Guide)[Panacea Holidays](https://expedia.co.uk/Panacea.d3000431554.Holidays-City-Breaks) ![Beautiful sunsets](https://images.trvl-media.com/place/3000431554/0e4e63ac-d470-468e-97e9-e5b3587cec19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Barbara Brogdon ![](https://images.trvl-media.com/place/3000431554/0e4e63ac-d470-468e-97e9-e5b3587cec19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Panacea Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=PETS) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=POOL) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=OCEAN_VIEW) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&travelerType=family_friendly) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&lodging=APARTMENT) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&lodging=CONDO) ## Check prices for these dates Tonight [17 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [18 Jan - 19 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panacea hotels ![Comfort Studio | Terrace/patio](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/7ddc9d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Private kitchen | Mini-fridge, microwave, coffee/tea maker, freezer](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/df64fc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Private kitchen | Mini-fridge, microwave, coffee/tea maker, freezer](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/b404a7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Panacea Motel [](https://www.expedia.co.uk/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) Panacea 9.0/10 Wonderful (142 reviews) "The room was clean. the ac was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elliot [](https://www.expedia.co.uk/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/3e99d756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/83d33573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/6939039a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/5b60f16d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Wakulla Springs [](https://www.expedia.co.uk/Tallahassee-Hotels-The-Lodge-At-Wakulla-Springs.h5411745.Hotel-Information) Crawfordville 9.4/10 Exceptional (1,002 reviews) "Clean, very friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariah [](https://www.expedia.co.uk/Tallahassee-Hotels-The-Lodge-At-Wakulla-Springs.h5411745.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/a22e2ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/6048f183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/d1920fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/551331a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Old Carrabelle Hotel [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Old-Carrabelle-Hotel.h121767092.Hotel-Information) Carrabelle 9.0/10 Wonderful (2 reviews) "Clean room, older property but had old Florida charm." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deirdre £58 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Old-Carrabelle-Hotel.h121767092.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/a52a90f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/9ff25f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/ab700b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/25adabe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Wakulla Inn & Suites [](https://www.expedia.co.uk/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) Crawfordville 8.8/10 Excellent (950 reviews) "Great hotel. Very good customer service and very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) claudina £93 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/c81957b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/d2e66c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/a2c8b110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/9928e089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Franklin Inn [](https://www.expedia.co.uk/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) Carrabelle 7.8/10 Good (456 reviews) "JJ was great great location clean room comfortable bed and good value. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal £66 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/93dee934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4b7008a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/aabba374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4f65d9b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wildwood Inn [](https://www.expedia.co.uk/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information) Crawfordville 8.6/10 Excellent (1,001 reviews) "Enjoyed our stay and would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey £94 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/9a81e303.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/b57f7efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch TV with cable channels](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/9652fe44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/d6fe4fb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Bay Golf & Pickleball Resort [](https://www.expedia.co.uk/Carrabelle-Hotels-St-James-Bay-Golf-Club.h23962755.Hotel-Information) Carrabelle 9.0/10 Wonderful (374 reviews) "Great staff! Lisa helped us with some issues the morning after check in, and the rest of our stay was pleasant. St. James Bay is always a nice place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca £98 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Carrabelle-Hotels-St-James-Bay-Golf-Club.h23962755.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/049ab2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/b073fdcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/b5016fe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Games room](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/413778f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Moorings Hotel and Marina [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) Carrabelle 8.4/10 Very good (39 reviews) "Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl £112 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01®ionId=3000431554&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels.d3000431554.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels.d3000431554.Travel-Guide-Hotels) ## Stay near popular Panacea attractions ### Alligator Point Beach 3.5/5 (2 reviews) Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635983992302) ### Bald Point State Park 4.6/5 (9 reviews) Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654045) ### Mashes Sand Beach Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635983994375) ### Wilson Beach Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874556768565592064) ### Panacea Springs Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874557096537096192) ### Public Beach Access Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874557052127805440) ### Woolley Park After visiting Woolley Park, make a plan to see the other sights and activities in Panacea. Amble around this relaxing area's beaches or seek out the fishing spots. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874556793735602176) ### Panacea Park After visiting Panacea Park, make a plan to see the other sights and activities in Panacea. Stroll along this relaxing area's beaches or simply enjoy its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874557102014853120) ## Learn more about Panacea Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails. [See all hotels in Panacea](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01&adults=2®ionId=3000431554) ![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=267&h=399&p=1&q=high) ## Top Panacea Hotel Reviews ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg) ### The Panacea Motel 10/10 Excellent "This was by far one of my most peaceful getaways, i book mini getaways very often due to the stress and nature of my job , Panacea motel was by far exceptional ! check in was super easy and they allow you to have a peace of mind by giving you space! everything was completed and i was in and out without even having to check in or out , They give you the space and resources to be self sufficient during your stay without need of any help, will definitely be booking again !!" [](https://expedia.co.uk/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay](https://images.trvl-media.com/lodging/107000000/106380000/106377800/106377762/82e3e83b_y.jpg) ### Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay 10/10 Excellent "Vert nice house, very clean and confortable , perfect for relax and fish on the dock, amazing fish, really nice host....ty nancy " [](https://expedia.co.uk/Panacea-Hotels-Waterfront-Home-200-Ft-Pier1st-Floor.h106377762.Hotel-Information) ![Best deal at Alligator Point](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/f2e6bb56_y.jpg) ### Best deal at Alligator Point 10/10 Excellent "Stay was great!" [](https://expedia.co.uk/Panacea-Hotels-Best-Deal-At-Alligator-Point.h33486730.Hotel-Information) ![BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.](https://images.trvl-media.com/lodging/23000000/22630000/22621300/22621298/2547a122_y.jpg) ### BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks. 10/10 Excellent "If you’re searching for the ideal Old Florida beach house, where time slows down and life moves at a different pace, this is it. We had a wonderful stay with our family of 4 and our dog (didn’t use 3 of the bedrooms, the house was bigger than expected). I used to come to alligator point as a child and haven’t been back in years, wanted to show my kids and husband this peaceful area of the forgotten coast. The house was wonderful and reminded me of the cottage my family had as a child, wooden beams and walls, beautiful old Florida style you don’t see much anymore. I loved the sunken sitting area and of course the beautiful beach views and also a long dock on the bay side. The kids enjoyed the pickleball courts and fishing beach and bay. Robin the host was great. Hope to come back again. " [](https://expedia.co.uk/Panacea-Hotels-BEACH-FRONT-To-BAY-With-Boatdock.h22621298.Hotel-Information) ![NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/eedfea7d_y.jpg) ### NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! 10/10 Excellent "Location is perfect! Woke up to a beautiful sunrise every morning. " [](https://expedia.co.uk/Panacea-Hotels-Spacious-4BR45BA-Bald-Point-Beach-Home-Perfect-For-Families-Groups.h118717563.Hotel-Information) ![Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +](https://images.trvl-media.com/lodging/108000000/107290000/107284100/107284077/5342dafe_y.jpg) ### Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes + 10/10 Excellent "Great place!! Owner was super communicative. Loved the golf cart and beach. We will def be back! Thank you!" [](https://expedia.co.uk/Panacea-Hotels-Private-Beachfront-W-Golf-Cart.h107284077.Hotel-Information) ![ Secluded Florida Beach Bungalow FALL SPECIAL 20% OFF!!](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/9dc8cf06_y.jpg) ### Secluded Florida Beach Bungalow FALL SPECIAL 20% OFF!! 10/10 Excellent "We had a wonderful stay at the Spotted Grouper. The cottage is quiet and peaceful, and the sunsets over the Gulf of Mexico were beautiful. We enjoyed walking on the beach, collecting shells, and really appreciated how close to nature the area is — including an unexpected bear sighting!We stayed in December, which was a great time to visit: cool and chilly mornings and evenings, with sunny, comfortably warm days. I traveled from Annapolis with my mom, and the trip was especially meaningful because we were visiting my son, who stayed with us. The space was perfect for spending time together and cooking meals as a family.The hostess was great — gracious and accommodating to our needs. The cottage was clean and inviting. We would absolutely stay here again and will definitely return when we’re in town visiting my son." [](https://expedia.co.uk/Panacea-Hotels-The-Spotted-Grouper-Old-Florida-Beach-Bungalow.h48526748.Hotel-Information) ![Hideaway Beach Cottage on waterfront with amazing views.](https://images.trvl-media.com/lodging/89000000/89000000/88994400/88994349/3f6eb453_y.jpg) ### Hideaway Beach Cottage on waterfront with amazing views. 10/10 Excellent "What a wonderful gem of a place! Fabulous location and so peaceful and beautiful directly on the water! We had a wonderful fire in the outdoor fire pit and the house had everything we needed for our stay. The hosts kept in touch and were easy to communicate with. Great stay. I’d definitely return for a longer stay!!!" [](https://expedia.co.uk/Panacea-Hotels-Hideaway-Beach-Cottage-On-Waterfront-With-Amazing-Views.h88994349.Hotel-Information) ![Seven bedroom family home on gulf to bay lot](https://images.trvl-media.com/lodging/54000000/53020000/53012800/53012796/00ffe1ac_y.jpg) ### Seven bedroom family home on gulf to bay lot 10/10 Excellent "Yes yes we had a great day" [](https://expedia.co.uk/Panacea-Hotels-Seven-Bedroom-Family-Home-On-Gulf-To-Bay-Lot.h53012796.Hotel-Information) ## More cheap stays in Panacea ![Franklin Inn](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/4470f88b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Franklin Inn 1589 US-98 Carrabelle FL £66 18 Jan - 19 Jan includes taxes & fees 7.8/10 Good! (456 reviews) [](https://expedia.co.uk/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) ![Best Western Wakulla Inn & Suites](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/9ff25f41_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Wakulla Inn & Suites 3292 Coastal Hwy 98 Crawfordville FL £93 2 Feb - 3 Feb includes taxes & fees 8.6/10 Excellent! (948 reviews) [](https://expedia.co.uk/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) ![The Moorings Hotel and Marina ](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/f34571a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Moorings Hotel and Marina 1000 Hwy 98 Carrabelle FL £112 20 Jan - 21 Jan includes taxes & fees 8.4/10 Very Good! (39 reviews) [](https://expedia.co.uk/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) ![Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!](https://images.trvl-media.com/lodging/122000000/121250000/121245500/121245426/1c35e8cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets! Crawfordville FL £262 25 Jan - 26 Jan includes taxes & fees 10/10 Exceptional! (4 reviews) [](https://expedia.co.uk/Crawfordville-Hotels-Shell-Point-Canal-Front-Home-Come-Enjoy-A-Carefree-Comfortable-Stay-In-Paradise.h121245426.Hotel-Information) ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Panacea Motel 1545 Coastal Hwy Panacea FL [Get rates](https://expedia.co.uk/Hotel-Search?startDate=31%2F01%2F2026&endDate=01%2F02%2F2026&selected=95071987&PinnedHotelID=95071987&HadPinnedHotel=true®ionId=3000431554) 9/10 Wonderful! (141 reviews) [](https://expedia.co.uk/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Pet friendly Kayak with the manatees](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/dad3a8f0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pet friendly Kayak with the manatees Crawfordville FL [Get rates](https://expedia.co.uk/Hotel-Search?startDate=31%2F01%2F2026&endDate=01%2F02%2F2026&selected=108408667&PinnedHotelID=108408667&HadPinnedHotel=true®ionId=3000431554) 9.8/10 Exceptional! (47 reviews) [](https://expedia.co.uk/Crawfordville-Hotels-Charming-3-Bedroom-House-With-AC-And-WiFi-In-Crawfordville.h108408667.Hotel-Information) ## Find out more about Panacea ### Top reasons to visit Panacea - **Stunning Beaches:** Panacea boasts beautiful, serene beaches perfect for relaxation and sunbathing. - **Outdoor Adventures:** The area offers ample opportunities for hiking, fishing, and exploring nearby state parks. - **Charming Accommodation:** Enjoy a variety of delightful lodgings, from cosy cottages to pet-friendly hotels. - **Picturesque Islands:** Explore nearby islands that showcase breathtaking natural beauty and wildlife. - **Welcoming Community:** Experience the friendly local culture and community-oriented atmosphere. ### Find great hotels near Panacea In Panacea, Florida, you'll discover a variety of accommodation options, including charming hotels and guesthouses tailored for all types of travellers. Whether you're seeking a pet-friendly retreat, an adventurous getaway, or a golf-themed holiday, Panacea offers lodgings that cater to your desires. With an array of motels and hotels available, you’re sure to find the perfect place to unwind and explore this picturesque coastal destination. - **[Hyatt House Tallahassee Capitol – University: ](https://www.expedia.co.uk/Tallahassee-Hotels-Hyatt-House-Tallahassee-Capitol-Univer.h58811398.Hotel-Information)** This 3-star hotel offers a blend of business sophistication and family-friendly amenities, making it an excellent choice for a variety of travellers. Located 18.0km from Panacea, Hyatt House features dedicated business facilities, including an accessible Business Centre and meeting rooms. Families will appreciate its child-friendly services, such as complimentary cribs and window guards for safety. Pet owners can also enjoy their stay, with certain restrictions in place. The hotel's welcoming atmosphere and emphasis on convenience make it a reliable option for those travelling with children and pets alike. - **[Best Western Wakulla Inn & Suites: ](https://www.expedia.co.uk/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information)** Just 3.7km from Panacea, this hotel is ideal for adventure seekers and business travellers. The Best Western Wakulla Inn & Suites boasts a 24-hour Business Centre and multiple meeting rooms, catering to corporate needs. For those looking for excitement, adventure sports like hiking, sailing, and snorkeling are readily available nearby. The hotel not only provides a comfortable stay but also acts as a gateway to thrilling outdoor experiences, ensuring guests can blend work with pleasure seamlessly. - **[Magnuson Hotel Wildwood Inn: ](https://www.expedia.co.uk/Tallahassee-Hotels-Magnuson-Hotel-Wildwood-Inn.h1532906.Hotel-Information)** Situated 4.3km from Panacea, this 3-star hotel caters to adventure enthusiasts, business travellers, and pet owners alike. With a variety of business amenities, including a Business Centre and meeting rooms, Magnuson Hotel ensures a productive stay. Guests can engage in a range of outdoor activities such as mountain biking, sailing, and boat tours, all within close proximity. The hotel’s pet-friendly policy, combined with its adventurous spirit, makes it an appealing choice for those who wish to explore the area with their furry companions. ### Where to stay in Panacea Panacea, Florida, is a hidden gem perfect for a relaxing beach getaway. Nestled in a stunning location, it offers a serene atmosphere ideal for outdoor enthusiasts and families alike. Explore nearby attractions that showcase friendly people and recreational activities, or unwind in charming cottages that enhance the tranquil vibe. With its scenic beauty and secluded charm, Panacea is an excellent choice for those seeking a peaceful retreat in the heart of Florida. - **[Alligator Point: ](https://www.expedia.co.uk/Alligator-Point-Hotels.d553248635975849030.Travel-Guide-Hotels)** Nestled along the Gulf Coast, Alligator Point is a charming village that offers a serene escape for beach lovers and outdoor enthusiasts. With its peak visitor seasons in March, July, and November, this area is perfect for those seeking sun-soaked adventures and picturesque scenery. The village boasts a variety of recreational areas, resorts, and golf courses, making it an ideal spot for relaxation and leisure. Nearby landmarks include stunning beaches and the natural beauty of national state parks and wetlands, inviting exploration and appreciation of the local ecosystem. - **[Saint Teresa: ](https://www.expedia.co.uk/Saint-Teresa-Hotels.d3000432006.Travel-Guide-Hotels)** This quaint village, located just a stone's throw from Panacea, is known for its inviting beaches and lush outdoor spaces. Saint Teresa experiences moderate seasonal visitor numbers, particularly in March and during the summer months of June and July. Travellers flock here for a delightful mix of recreation and scenery, with ample opportunities for golf and leisurely strolls along the shoreline. The proximity to national state parks and wetlands enhances the area's appeal, offering a diverse range of activities for nature lovers and outdoor adventurers alike. - **[Ochlockonee Bay: ](https://www.expedia.co.uk/Ochlockonee-Bay-Hotels.d553248635975855809.Travel-Guide-Hotels)** A hidden gem in the Panacea region, Ochlockonee Bay captivates visitors with its stunning landscapes and adventurous spirit. With an influx of tourists peaking in March, July, and November, this village is perfect for those seeking outdoor activities and scenic beauty. From recreational areas to golf courses, there's no shortage of ways to enjoy the surrounding environment. The nearby beaches and protected wetlands provide excellent opportunities for exploration, making Ochlockonee Bay a must-visit destination for anyone looking to immerse themselves in Florida's natural wonders. ### Things to do in and around Panacea Panacea, Florida, is an idyllic destination for beach lovers and outdoor enthusiasts, offering stunning scenery and a tranquil coastal getaway. Visitors can explore recreational areas, engage in educational activities, and unwind at local resorts. This charming spot is perfect for those seeking relaxation and adventure amidst nature's beauty. **Shopping** In Panacea, you can enjoy local shopping experiences. If you're up for a drive, visit Tallahassee Downtown Market, 18.0km away, for a vibrant public market atmosphere. Also, Governor's Square Mall, 18.0km away, offers entertainment and shopping, while Woodville Commons, 13.7km away, provides a family-friendly shopping area. **Recreation** Woolley Park in Panacea offers a serene environment perfect for relaxation and wellness activities amidst nature. Just 3.7km away, Myron B Hodge City Park provides a tranquil space for rejuvenation, while St. James Bay Golf Club, located 8.1km away, combines sport and outdoor leisure in a picturesque setting. **Adventure** Explore the Tallahassee-St. Marks Historic Railroad State Trail, located 18.0km from Panacea, for a scenic hike surrounded by nature. Alternatively, visit the Tom Brown Tennis Center, 19.3km away, for an exhilarating tennis experience. Don't miss the Tallahassee-Saint Marks Historic Railroad Trail State Park, 16.8km from Panacea, for more outdoor adventures. **Nightlife** Experience the vibrant nightlife at Theatre Tallahassee, located 19.3km from Panacea. Enjoy captivating performances in a venue that exudes culture and romance, perfect for a night out with family or a special someone. Immerse yourself in the local arts scene for a memorable evening. ### Booking tips and Expedia advantages for Panacea To save money on your trip to Panacea, consider visiting during the cheaper months of July and December to January, as hotel prices drop. Booking on a Monday can also yield lower rates compared to Fridays. Use Expedia’s search tool to find budget-friendly accommodations by sorting results from lowest to highest price and applying filters for eco-certified options. Additionally, consider package deals that combine flights, hotels, and activities for extra savings. Explore free activities in the area, and rely on affordable public transport for getting around. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can organise your results to display prices from lowest to highest, allowing you to identify the most affordable hotels first. Additionally, you can refine your options by hotel type; for instance, selecting the “Eco-certified” filter will showcase sustainable and environmentally friendly hotels that are available for booking. - **Consider bundling your trip:** You can potentially save money by combining your Panacea hotel reservation with your flights and activities through an Expedia package deal. ### Find the best attractions in Panacea Panacea, Florida, is a delightful destination ideal for beach lovers and outdoor enthusiasts, offering stunning scenery and various attractions. Visitors can explore local beaches, picturesque islands, and nearby state parks, all perfect for experiencing the natural beauty of the area. Whether you're seeking relaxation or adventure, Panacea provides ample opportunities for an unforgettable holiday filled with seaside charm and outdoor activities. - **Alligator Point Beach:** Enjoy the serene beach vibes at Alligator Point Beach, a hidden gem ideal for relaxation and sunbathing. The soft sands and gentle waves create a perfect seaside escape. - **Bald Point State Park:** Experience adventure at Bald Point State Park, where stunning scenery meets outdoor activities. Explore hiking trails, birdwatching, and picturesque views of the Gulf, perfect for nature enthusiasts. - **USS Mohawk CGC Veterans Memorial Reef:** Discover the cultural significance of the USS Mohawk CGC Veterans Memorial Reef, an underwater attraction that honours veterans and offers a unique diving experience amidst marine life. ### Best time to go to Panacea The best time to visit Panacea is dependant on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 53.6°F (12.0°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 57.6°F (14.2°C) | Light Rain | Mostly Sunny | Average | Average | | March | 62.4°F (16.9°C) | Light Rain | Mostly Sunny | Average | Average | | April | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Moderately High | Average | | May | 74.8°F (23.8°C) | Light Rain | Mostly Sunny | Average | Average | | June | 80.4°F (26.9°C) | Moderate Rain | Mostly Sunny | Moderately High | Average | | July | 81.7°F (27.6°C) | Moderate Rain | Mostly Sunny | Moderately High | Slightly Low | | August | 81.7°F (27.6°C) | Moderate Rain | Mostly Sunny | Average | Slightly High | | September | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Average | Slightly High | | October | 71.1°F (21.7°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly High | | November | 61.9°F (16.6°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | December | 57.6°F (14.2°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | ### The nearest major airports for your trip to Panacea For your visit to Panacea, Florida, the nearest major airport is Tallahassee International Airport ([TLH](https://www.expedia.co.uk/Tallahassee-Intl-Airport-Hotels.0-aTLH-0.Travel-Guide-Filter-Hotels)), situated 16.2km away. Excellent hotel options near TLH include the 4-star [Hotel Duval](https://www.expedia.co.uk/Tallahassee-Hotels-Hotel-Duval.h9568.Hotel-Information), which is 3.1km from the airport and offers transfers and shuttles, and the 3.5-star Hotel Indigo Tallahassee - Collegetown, located 2.5km away, with accessible transport services. Another good choice is the 3-star [Wyndham Garden Tallahassee Capitol](https://www.expedia.co.uk/Tallahassee-Hotels-Wyndham-Garden-Tallahassee-Capitol.h538597.Hotel-Information), positioned 3.7km from TLH, providing convenient access for travellers. These accommodations ensure a comfortable stay while facilitating easy airport access for your journey. ## Frequently asked questions ### What is the best area to stay in Panacea? > This area is the heart of Panacea, offering direct access to the Gulf of Mexico's tranquil waters. You'll find most of the local seafood restaurants and shops concentrated along US-98, making it very convenient. It's a relaxed, coastal community known for its fishing and natural beauty. > > > Families often find this area ideal due to its proximity to the water-based activities. Many accommodations here offer easy access to fishing charters, boat rentals, and paddleboarding opportunities in the bay. The educational exhibits at the Gulf Specimen Marine Lab are also a short walk away, providing an engaging experience for children and adults alike. > > > Couples looking for a quiet escape will appreciate the peaceful atmosphere and scenic views. The waterfront properties often provide lovely spots to relax and enjoy the sunset over the bay, with several local eateries offering fresh seafood right on the water. ### What are the best hotels in Panacea that travellers recommend? > The Panacea Motel, with a 9.0 rating, offers excellent value and is praised by guests for its comfortable beds and nice towels. It provides free self-parking and early check-in is often available. The motel is conveniently located near local attractions such as Woolley Park, just 1.0 km away, Gulf Specimen Public Aquarium, 1.5 km away, and Panacea Park, which is 1.2 km from the property. ### What are the top pet-friendly hotels in Panacea? > The Panacea Motel, with a very good 9.0 rating, is an excellent choice for travellers with pets as both dogs and cats are permitted. Guests frequently mention the good beds and the nice towels, alongside the good value for the price. The hotel also offers early check-in, which can be very convenient. It is well-located near local attractions such as Woolley Park, just 1.0 km away, Gulf Specimen Public Aquarium, 1.5 km away, and Panacea Park, 1.2 km away. ### What are the best budget hotels in Panacea? > This motel, with a 9.0 rating, is frequently praised by guests for its good value and comfortable beds, with many noting the nice towels provided. It offers free WiFi and complimentary self-parking. Early check-in is also available, which can be very convenient. The Panacea Motel is handily located near local attractions, being only 0.3 km from Panacea Springs, 1.0 km from Woolley Park, and 1.2 km from Panacea Park. ### What are the best hotels in Panacea near Woolley Park? > The Panacea Motel, with a 9.0 rating, is conveniently located just 1.0 km from Woolley Park. Guests often mention the comfortable beds and the good value for money. The motel also offers free WiFi and complimentary self-parking, and early check-in is available. It is also only 1.5 km from the Gulf Specimen Public Aquarum and 1.2 km from Panacea Park. ### When is the best time to go to Panacea? > During these periods, the weather is pleasantly warm, with comfortable temperatures ranging from the low 20s to high 20s Celsius. You'll find fewer crowds compared to the peak summer season, making it ideal for a relaxing and unhurried experience. It's superb for enjoying outdoor activities like kayaking, fishing, or exploring the nature trails without the intense heat and humidity of summer. > > > Travellers looking for a tranquil escape will appreciate the calm waters and the opportunity to spot local wildlife, such as manatees and various bird species. The mild weather makes it a great time for couples to enjoy romantic walks along the coastline or explore the local seafood restaurants. > > > Conversely, while summer (June to August) offers very warm weather for swimming, it also brings higher humidity, more frequent thunderstorms, and larger crowds. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Panacea hotel booking with Expedia? ### How much is the nightly rate at a Panacea hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Alligator Point Hotels ](https://www.expedia.co.uk/Alligator-Point-Hotels.d553248635975849030.Travel-Guide-Hotels) - [Hotels near Bobby Bowden Field at Doak Campbell Stadium ](https://www.expedia.co.uk/Bobby-Bowden-Field-At-Doak-Campbell-Stadium-Hotels.0-l6065205-0.Travel-Guide-Filter-Hotels) - [Capitol Hill Hotels ](https://www.expedia.co.uk/Capitol-Hill-Tallahassee-Hotels.0-n553248635976470747-0.Travel-Guide-Filter-Hotels) - 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