Title: Panacea Holidays 2025 from $953 | Expedia.co.uk [Panacea Travel Guide](https://expedia.co.uk/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.co.uk/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Holiday Rentals in Panacea](https://expedia.co.uk/Panacea-Holiday-Rentals.d3000431554.Travel-Guide-HolidayRentals)[Panacea Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panacea.d3000431554.Car-Hire-Guide) ![](https://images.trvl-media.com/place/553248635975849030/3897830d-0364-4ff9-a71f-9d53f3b3a805.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Panacea Holidays from £711 ## Book a Hotel + Flight or Car together to unlock savings Photo by Barbara Brogdon - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected #### Your Panacea Holiday When you book a holiday package to Panacea, you can relax and enjoy your getaway knowing that all your travel plans have been worked out ahead of time. Discover the wonders of this city while based in a neighbourhood like Ochlockonee Bay, which is great for nature. Up for some sightseeing? A trip to Panacea isn't complete without visiting [Mashes Sand Beach](https://www.expedia.co.uk/Mashes-Sand-Beach-Panacea.d553248635983994375.Attraction), [Ochlockonee River State Park](https://www.expedia.co.uk/Ochlockonee-River-State-Park-Sopchoppy.d553248621532653556.Attraction) and other popular attractions. Check out Expedia's wide range of travel options and start organising your ideal holiday to Panacea now. ## Top Panacea Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Franklin Inn](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/4470f88b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Franklin Inn £711 per person 23 Oct - 28 Oct found 1 day ago Return direct flight included London (LON) to Tallahassee (TLH) 7.8/10 Good! (434 reviews) Loved the area and people are very friendly. Reviewed on 8 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-23/2025-10-28/?FromAirport=LON&Destination=TLH&NumRoom=1&NumAdult=2&NumChild=0&hotelId=45034076&paandie=true&dealMarker=FKGU2dG1zgA43fWvxC0N6xPxaLqXVN0X3jp4jSEa-VF6FiyaaWvSBxGWLzb0l64C) ![St James Bay Golf & Pickleball Resort](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/bb4da5df_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### St James Bay Golf & Pickleball Resort £828 per person 23 Oct - 28 Oct found 1 day ago Return direct flight included London (LON) to Tallahassee (TLH) 9/10 Wonderful! (354 reviews) Property layout to access their amenities was good. Reviewed on 10 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-23/2025-10-28/?FromAirport=LON&Destination=TLH&NumRoom=1&NumAdult=2&NumChild=0&hotelId=23962755&paandie=true&dealMarker=o08y-cfHdJd2MTCJrObmg_ORuMZSBxVjFStGqzdnbHuBo-Mm1tW55dWdk5GI2sxf) ![The Salty Snapper](https://images.trvl-media.com/lodging/91000000/90240000/90230500/90230408/ae561d27_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Salty Snapper £969 per person 23 Oct - 28 Oct found 1 day ago Return direct flight included London (LON) to Tallahassee (TLH) 7.4/10 Good! (3 reviews) The property was for sale, a lot o things need work, like the dishwasher was missing the wheels on one side of the bottom basket, we had people looking at the roof, the siding, measuring windows, emptying the septic system, all while we were on our vacation Reviewed on 14 Aug 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-23/2025-10-28/?FromAirport=LON&Destination=TLH&NumRoom=1&NumAdult=2&NumChild=0&hotelId=90230408&paandie=true&dealMarker=FKGU2dG1zgA43fWvxC0N6xPxaLqXVN0X3jp4jSEa-VHPgNYgW_pIOHE1rDZ-BgWy) ![The Moorings Hotel and Marina ](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/f34571a2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Moorings Hotel and Marina £823 per person 23 Oct - 28 Oct found 1 day ago Return direct flight included London (LON) to Tallahassee (TLH) 8.4/10 Very Good! (34 reviews) Quaint hotel on marina with old Florida charm. Room was very clean but also very musty - mildew coming from AC unit was overwhelming. Bed was awful - literally lumpy with loose headboard that sounded like an accordion when you moved at all. We wedged towels to shut it up. Almost left to pay to stay at a second hotel. Reviewed on 6 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-23/2025-10-28/?FromAirport=LON&Destination=TLH&NumRoom=1&NumAdult=2&NumChild=0&hotelId=103241082&paandie=true&dealMarker=o08y-cfHdJd2MTCJrObmg_ORuMZSBxVjFStGqzdnbHuTnp0BlgqLTR7KeIvGP6ML) ![Buccaneer Inn](https://images.trvl-media.com/lodging/20000000/19780000/19770600/19770521/7cfc935e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Buccaneer Inn East End £837 per person 23 Oct - 28 Oct found 1 day ago Return direct flight included London (LON) to Tallahassee (TLH) 8.2/10 Very Good! (913 reviews) Not updated but very close to beach access. We will be back! Reviewed on 1 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-23/2025-10-28/?FromAirport=LON&Destination=TLH&NumRoom=1&NumAdult=2&NumChild=0&hotelId=19770521&paandie=true&dealMarker=FKGU2dG1zgA43fWvxC0N6xPxaLqXVN0X3jp4jSEa-VE2aXT4CJUd0nPXFkpTmodg) ## Panacea Essential Information | Language | English | | --- | --- | | Currency | U.S dollars | | Closest Airport | Tallahassee Intl. Airport (TLH) | | Population | 820 | | Max Temp Winter | 18ºC | | Max Temp Summer | 32ºC | | Top Sights | [Shell Point Beach](https://www.expedia.co.uk/Shell-Point-Beach-Tallahassee.d553248635976197335.Attraction), [Alligator Point Beach](https://www.expedia.co.uk/Alligator-Point-Beach-Panacea.d553248635983992302.Attraction) and [Bald Point State Park](https://www.expedia.co.uk/Bald-Point-State-Park-Panacea.d553248621532654045.Attraction) | ## Top hotels in Panacea ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Panacea Motel 1545 Coastal Hwy, Panacea, FL £98 29 Sept - 30 Sept includes taxes & fees 9/10 Wonderful! (114 reviews) Awesome Little Motel - stay here!! "Amazing place. Bed so comfortable. Stay here !!" Reviewed on 31 Aug 2025 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F09%2F2025&endDate=30%2F09%2F2025&selected=95071987&PinnedHotelID=95071987&HadPinnedHotel=true®ionId=3000431554) ![7 Bedroom Beach House with POOL!! Gulf Front and Bay Front](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/df15e6fc_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front Alligator Point, FL £1,476 16 Sept - 17 Sept includes taxes & fees 9.8/10 Exceptional! (98 reviews) "We had an awesome time. Wonderful well stocked home. We will definitely be back." Reviewed on 27 Jul 2025 [](https://expedia.co.uk/Hotel-Search?startDate=16%2F09%2F2025&endDate=17%2F09%2F2025&selected=19008298&PinnedHotelID=19008298&HadPinnedHotel=true®ionId=3000431554) ![ Secluded Florida Beach Bungalow](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/9dc8cf06_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Secluded Florida Beach Bungalow Panacea, FL 9.8/10 Exceptional! (221 reviews) "The retro/beach themes of the house were cool. The house was very clean and had everything we needed. Loved the screened in porch. Tides affected beach access at the end of the street, but there are other public beach access available." Reviewed on 12 Aug 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=29%2F09%2F2025&endDate=30%2F09%2F2025&selected=48526748&PinnedHotelID=48526748&HadPinnedHotel=true®ionId=3000431554) [](https://expedia.co.uk/Hotel-Search?startDate=29%2F09%2F2025&endDate=30%2F09%2F2025&selected=48526748&PinnedHotelID=48526748&HadPinnedHotel=true®ionId=3000431554) [See all 515 properties in Panacea](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=16%2F09%2F2025&endDate=17%2F09%2F2025®ionId=3000431554) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit ![Bald Point State Park](https://mediaim.expedia.com/destination/1/a26f5e12f28d6a9b90f0a1284fcb27fc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Bald Point State Park You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this family-friendly area or seek out the fishing spots. [](https://expedia.co.uk/Bald-Point-State-Park-Panacea.d553248621532654045.Attraction) ## More trip options - Nearby Cities - Expedia's Latest Trends - [Orlando Holidays](https://expedia.co.uk/Orlando.d178294.Holidays-City-Breaks) - [Miami Holidays](https://expedia.co.uk/Miami.d178286.Holidays-City-Breaks) - [Fort Lauderdale Holidays](https://expedia.co.uk/Fort-Lauderdale.d601750.Holidays-City-Breaks) - [Tampa Holidays](https://expedia.co.uk/Tampa.d602996.Holidays-City-Breaks) - [Jacksonville Holidays](https://expedia.co.uk/Jacksonville.d602997.Holidays-City-Breaks) - [St. Petersburg - Clearwater Holidays](https://expedia.co.uk/St-Petersburg-Clearwater.d178310.Holidays-City-Breaks) ### Expedia's Latest Trends Hotels - [Key West Accommodation](https://expedia.co.uk/Key-West-Hotels.d1187.Travel-Guide-Hotels) - [Sanibel Accommodation](https://expedia.co.uk/Sanibel-Hotels.d9791.Travel-Guide-Hotels) - [Sarasota Accommodation](https://expedia.co.uk/Sarasota-Hotels.d602719.Travel-Guide-Hotels) - [Cocoa Beach Accommodation](https://expedia.co.uk/Cocoa-Beach-Hotels.d6549.Travel-Guide-Hotels) - [Daytona Beach Accommodation](https://expedia.co.uk/Daytona-Beach-Hotels.d6023995.Travel-Guide-Hotels) - [Destin Accommodation](https://expedia.co.uk/Destin-Hotels.d6906.Travel-Guide-Hotels) - [Naples Accommodation](https://expedia.co.uk/Naples-Hotels.d602724.Travel-Guide-Hotels) - [Key Largo Accommodation](https://expedia.co.uk/Key-Largo-Hotels.d8369.Travel-Guide-Hotels) Flights - [Flights to TPA](https://expedia.co.uk/Cheap-Flights-To-Sarasota.d602719.Travel-Guide-Flights) - [Flights to MLB](https://expedia.co.uk/Cheap-Flights-To-Christmas.d6154232.Travel-Guide-Flights) - [Flights to DAB](https://expedia.co.uk/Cheap-Flights-To-Melbourne.d2342.Travel-Guide-Flights) - [Flights to TLH](https://expedia.co.uk/Cheap-Flights-To-Tallahassee.d6048214.Travel-Guide-Flights) - [Flights to FMY](https://expedia.co.uk/Cheap-Flights-To-Fort-Myers.d602729.Travel-Guide-Flights) - [Flights to ORL](https://expedia.co.uk/Cheap-Flights-To-Davenport.d6301.Travel-Guide-Flights) - [Flights to DAB](https://expedia.co.uk/Cheap-Flights-To-Cape-Canaveral.d6484.Travel-Guide-Flights) - [Flights to PNS](https://expedia.co.uk/Cheap-Flights-To-Pensacola.d6023331.Travel-Guide-Flights) - [Flights to ORL](https://expedia.co.uk/Cheap-Flights-To-Sanford.d9845.Travel-Guide-Flights) - [Flights to PBI](https://expedia.co.uk/Cheap-Flights-To-Palm-Beach.d9061.Travel-Guide-Flights) - [Flights to DAB](https://expedia.co.uk/Cheap-Flights-To-Daytona-Beach.d6023995.Travel-Guide-Flights) - [Flights to EYW](https://expedia.co.uk/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights) Cars - [Car rental in Key West](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Key-West.d1187.Car-Hire-Guide) Activities - [Things to do in Winter Garden](https://expedia.co.uk/Things-To-Do-In-Winter-Garden.d7898.Travel-Guide-Activities) - [Things to do in Holiday](https://expedia.co.uk/Things-To-Do-In-Holiday.d10343.Travel-Guide-Activities) Packages - [Trips to Naples](https://expedia.co.uk/Naples.d602724.Holidays-City-Breaks) - [Trips to Panama City Beach](https://expedia.co.uk/Panama-City-Beach.d8021.Holidays-City-Breaks) - [Trips to Siesta Key](https://expedia.co.uk/Siesta-Key.d6881.Holidays-City-Breaks) - [Trips to Heathrow](https://expedia.co.uk/Heathrow.d11967.Holidays-City-Breaks) - [Trips to Key West](https://expedia.co.uk/Key-West.d1187.Holidays-City-Breaks) General - [Visit Tallahassee](https://expedia.co.uk/Tallahassee.dx6048214) - [Visit Boca Raton](https://expedia.co.uk/Boca-Raton.dx6317) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)