Title: Panacea Travel Guide: Best of Panacea, Florida Travel 2026 | Expedia.co.uk [Hotels in Panacea](https://expedia.co.uk/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Holiday Rentals in Panacea](https://expedia.co.uk/Panacea-Holiday-Rentals.d3000431554.Travel-Guide-HolidayRentals)[Panacea Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panacea.d3000431554.Car-Hire-Guide)[Panacea Holidays](https://expedia.co.uk/Panacea.d3000431554.Holidays-City-Breaks) # Panacea Travel Guide ## Tourist Guide ![Florida, Panacea](https://images.trvl-media.com/place/3000431554/ef7510fd-7401-44b7-8add-0b033672a2ae.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Florida, Panacea](https://images.trvl-media.com/place/3000431554/ef7510fd-7401-44b7-8add-0b033672a2ae.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Sunset at Panacea, Florida, USA.](https://images.trvl-media.com/place/3000431554/6157a67a-7509-4ca1-8e42-ce7509210e67.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Beautiful uncrowned beaches](https://images.trvl-media.com/place/553248635975849030/3897830d-0364-4ff9-a71f-9d53f3b3a805.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Panacea Things to do - Top hotels in Panacea - Top Holiday Rentals in Panacea ![5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch](https://images.trvl-media.com/lodging/75000000/74830000/74824400/74824331/169d337b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch Panacea FL Stay at this beach holiday home in Alligator Point. Enjoy free Wi-Fi, a beach locale and a garden. Popular attractions Bald Point State Park and Mashes Sand ... 9.8/10 Exceptional! (80 reviews) The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again! Reviewed on 19 Dec 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=74824331&PinnedHotelID=74824331&HadPinnedHotel=true®ionId=3000431554) [](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=74824331&PinnedHotelID=74824331&HadPinnedHotel=true®ionId=3000431554) ![7 Bedroom Beach House with POOL!! Gulf Front and Bay Front](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/df15e6fc_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front Alligator Point FL £1,414 9 Feb - 10 Feb includes taxes & fees Stay at this beach holiday home in Alligator Point. Enjoy free Wi-Fi, private pools and a beach locale. Popular attractions Public Beach Access and Alligator ... 10/10 Exceptional! (101 reviews) Our family had a great time. There was plenty of space for everyone to be alone when they needed it, but absolutely plenty of space to come together. Kitchen was fully stocked with all of the pots/pans/utensils needed. The house is right on the water with convenient access. The front yard was perfect ... Reviewed on 10 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=19008298&PinnedHotelID=19008298&HadPinnedHotel=true®ionId=3000431554) ![ Secluded Florida Beach Bungalow FALL SPECIAL 20% OFF!!](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/9dc8cf06_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Secluded Florida Beach Bungalow FALL SPECIAL 20% OFF!! Panacea FL Stay at this holiday home in Alligator Point. Enjoy free Wi-Fi, a garden and laundry facilities. Popular attractions Bald Point State Park and Mashes Sand Beach ... 9.8/10 Exceptional! (227 reviews) We had a wonderful stay at the Spotted Grouper. The cottage is quiet and peaceful, and the sunsets over the Gulf of Mexico were beautiful. We enjoyed walking on the beach, collecting shells, and really appreciated how close to nature the area is — including an unexpected bear sighting!We stayed in ... Reviewed on 23 Dec 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=48526748&PinnedHotelID=48526748&HadPinnedHotel=true®ionId=3000431554) [](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=48526748&PinnedHotelID=48526748&HadPinnedHotel=true®ionId=3000431554) [See all 505 properties in Panacea](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=31%2F01%2F2026&endDate=01%2F02%2F2026®ionId=3000431554) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +](https://images.trvl-media.com/lodging/108000000/107290000/107284100/107284077/5342dafe_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes + Alligator Point FL Stay at this beach holiday home in Alligator Point. Enjoy free Wi-Fi, a beach locale and a sauna. Popular attractions Bald Point State Park and Mashes Sand Beach ... 10/10 Exceptional! (63 reviews) What a wonderful way to spend a few days. Great listing, well equipped with everything you could possibly need for fun time at the beach. Each day begins with a sunrise right over the water. Even in the winter, this home is well equipped for a great time. I especially enjoyed the stars and spending ... Reviewed on 20 Jan 2026 [](https://expedia.co.uk/Panacea-Hotels-Private-Beachfront-W-Golf-Cart.h107284077.Hotel-Information) ![5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch](https://images.trvl-media.com/lodging/75000000/74830000/74824400/74824331/169d337b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch Panacea FL Stay at this beach holiday home in Alligator Point. Enjoy free Wi-Fi, a beach locale and a garden. Popular attractions Bald Point State Park and Mashes Sand ... 9.8/10 Exceptional! (80 reviews) The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again! Reviewed on 19 Dec 2025 [](https://expedia.co.uk/Panacea-Hotels-New-SEAcluded-Paradise-Updated-Steps-To-The-Beach-Oceanfront-Fish.h74824331.Hotel-Information) ![Hideaway Beach Cottage on waterfront with amazing views.](https://images.trvl-media.com/lodging/89000000/89000000/88994400/88994349/3f6eb453_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hideaway Beach Cottage on waterfront with amazing views. Panacea FL Stay at this beach cottage in Panacea. Enjoy free Wi-Fi, a beach locale and a garden. Popular attractions Bayside Marina and Silver Lake are located nearby. 9.8/10 Exceptional! (60 reviews) What a wonderful gem of a place! Fabulous location and so peaceful and beautiful directly on the water! We had a wonderful fire in the outdoor fire pit and the house had everything we needed for our stay. The hosts kept in touch and were easy to communicate with. Great stay. I’d definitely return ... Reviewed on 15 Dec 2025 [](https://expedia.co.uk/Panacea-Hotels-Hideaway-Beach-Cottage-On-Waterfront-With-Amazing-Views.h88994349.Hotel-Information) [See all properties in Panacea](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000431554&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Panacea hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431554&startDate=2026-01-30&endDate=2026-01-31)[30 Jan - 31 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431554&startDate=2026-01-30&endDate=2026-01-31) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431554&startDate=2026-01-31&endDate=2026-02-01)[31 Jan - 1 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431554&startDate=2026-01-31&endDate=2026-02-01) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431554&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026)[30 Jan - 1 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431554&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026) ### Popular places to visit #### Alligator Point Beach Why not spend a lazy afternoon at Alligator Point Beach during your trip to Alligator Point? [](https://expedia.co.uk/Alligator-Point-Beach-Panacea.d553248635983992302.Attraction) #### Bald Point State Park You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this relaxing area or seek out the fishing spots. [](https://expedia.co.uk/Bald-Point-State-Park-Panacea.d553248621532654045.Attraction) #### Mashes Sand Beach Why not spend a lazy afternoon at Mashes Sand Beach during your trip to Panacea? Amble around this relaxing area's beaches or seek out the fishing spots. [](https://expedia.co.uk/Mashes-Sand-Beach-Panacea.d553248635983994375.Attraction) #### Wilson Beach Why not spend a lazy afternoon at Wilson Beach during your trip to Panacea? Amble around this relaxing area's beaches or seek out the fishing spots. [](https://expedia.co.uk/Wilson-Beach-Panacea.d874556768565592064.Attraction) #### Panacea Springs After visiting Panacea Springs, make a plan to see the other sights and activities in Panacea. Amble around this relaxing area's beaches or seek out the fishing spots. [](https://expedia.co.uk/Panacea-Springs-Panacea.d874557096537096192.Attraction) #### Public Beach Access Explore the great outdoors at Public Beach Access, a lovely green space in Alligator Point. [](https://expedia.co.uk/Public-Beach-Access-Panacea.d874557052127805440.Attraction) ## Cities near Panacea ![Crooked River Lighthouse Carrabelle Florida on the Forgotten Gulf Coast Panhandle 09.15.2025](https://images.trvl-media.com/place/86458/38e8e6d4-e190-45ec-aa99-cf5cb950c527.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Carrabelle ![The St. Marks Lighthouse is the second oldest lighthouse in Florida. It was originally built in 1828 and has gone through many reconstruction period including being renovated in 2018. While it is a main attraction, the refuge itself is renown for major bird migrations and for seeing alligators. ](https://images.trvl-media.com/place/183090/96b74c83-d167-4c80-a207-8d739fa7562c.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Crawfordville ![What an amazing place to watch the sunrise. #localgem](https://images.trvl-media.com/place/6355340/439d98d2-c423-4772-bf92-7dc8617b2a28.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Sopchoppy ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [Alligator Point Hotels ](https://www.expedia.co.uk/Alligator-Point-Hotels.d553248635975849030.Travel-Guide-Hotels) - [Carrabelle Hotels ](https://www.expedia.co.uk/Carrabelle-Hotels.d86458.Travel-Guide-Hotels) - [Crawfordville Hotels ](https://www.expedia.co.uk/Crawfordville-Hotels.d183090.Travel-Guide-Hotels) - [Caravan Parks in Dog Island ](https://www.expedia.co.uk/Dog-Island-Caravan-Parks.d553248633992414405-aaCaravanParks.Travel-Guide-Accommodation) - 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[St. Marks Hotels ](https://www.expedia.co.uk/St-Marks-Hotels.d6348000.Travel-Guide-Hotels) - [Hotels near Tallahassee Intl. ](https://www.expedia.co.uk/Tallahassee-Intl-Airport-Hotels.0-aTLH-0.Travel-Guide-Filter-Hotels) - [Wakulla Beach Hotels ](https://www.expedia.co.uk/Wakulla-Beach-Hotels.d553248635975849044.Travel-Guide-Hotels) - [Wakulla Springs Hotels ](https://www.expedia.co.uk/Wakulla-Springs-Hotels.d553248635077778744.Travel-Guide-Hotels) - [Hotels near Wakulla Springs State Park ](https://www.expedia.co.uk/Wakulla-Springs-State-Park-Hotels.0-l6089879-0.Travel-Guide-Filter-Hotels) - [Flights to Carrabelle ](https://www.expedia.co.uk/Cheap-Flights-To-Carrabelle.d86458.Travel-Guide-Flights) - [Flights to Dog Island ](https://www.expedia.co.uk/Cheap-Flights-To-Dog-Island.d553248633992414405.Travel-Guide-Flights) - [Flights from Tallahassee Intl. ](https://www.expedia.co.uk/lp/airports/tlh/flights-from-tallahassee-intl-airport) - [Delta Atlanta (ATL) to Tallahassee (TLH) flights ](https://www.expedia.co.uk/lp/flight-routes/delta-from-hartsfield-jackson-atlanta-intl-to-tallahassee-intl/dl/atl/tlh) - 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[Visit Bristol ](https://www.expedia.co.uk/Bristol.dx553248625390928739) - [Visit Callaway ](https://www.expedia.co.uk/Callaway.dx3000430875) - [Visit Cape San Blas ](https://www.expedia.co.uk/Cape-San-Blas.dx3000383251) - [Carrabelle Holidays ](https://www.expedia.co.uk/Carrabelle.d86458.Holidays-City-Breaks) - [Visit Carrabelle ](https://www.expedia.co.uk/Carrabelle.dx86458) - [Visit Central West Coast Florida ](https://www.expedia.co.uk/Central-West-Coast-Florida.dx6048187) - [Visit Chiefland ](https://www.expedia.co.uk/Chiefland.dx6094701) - [Visit Chipley ](https://www.expedia.co.uk/Chipley.dx7433) - [Visit Crawfordville ](https://www.expedia.co.uk/Crawfordville.dx183090) - [Dog Island Holidays ](https://www.expedia.co.uk/Dog-Island.d553248633992414405.Holidays-City-Breaks) - [Visit Dog Island ](https://www.expedia.co.uk/Dog-Island.dx553248633992414405) - [Visit Florida Panhandle ](https://www.expedia.co.uk/Florida-Panhandle.dx6048212) - [Visit Gulf Resort Beach ](https://www.expedia.co.uk/Gulf-Resort-Beach.dx553248635976196079) - [Visit Horseshoe Beach ](https://www.expedia.co.uk/Horseshoe-Beach.dx6352156) - [Visit Jasper ](https://www.expedia.co.uk/Jasper.dx8028) - [Visit Lynn Haven ](https://www.expedia.co.uk/Lynn-Haven.dx6047224) - [Visit Marianna ](https://www.expedia.co.uk/Marianna.dx10646) - [Visit Mexico Beach ](https://www.expedia.co.uk/Mexico-Beach.dx132781) - [Visit Biltmore Beach ](https://www.expedia.co.uk/Panama-City-Beach-Biltmore-Beach.dx553248635976471384) - [Visit Rosemary Beach ](https://www.expedia.co.uk/Panama-City-Beach-Rosemary-Beach.dx6139932) - [Visit Panama City Beach ](https://www.expedia.co.uk/Panama-City-Beach.dx8021) - [Visit Pinetta ](https://www.expedia.co.uk/Pinetta.dx553248635974901121) - [Visit Shell Island ](https://www.expedia.co.uk/Shell-Island.dx6312110) - [Visit Shell Island ](https://www.expedia.co.uk/Shell-Island.dx810255962224594944) - [Visit Sopchoppy ](https://www.expedia.co.uk/Sopchoppy.dx6355340) - [Visit St. George Island State Park ](https://www.expedia.co.uk/St-George-Island-State-Park.dx6294780) - [Visit St. George Island ](https://www.expedia.co.uk/St-George-Island.dx602549) - [St. Marks Holidays ](https://www.expedia.co.uk/St-Marks.d6348000.Holidays-City-Breaks) - [Visit Capitol Hill ](https://www.expedia.co.uk/Tallahassee-Capitol-Hill.dx553248635976470747) - [Visit Lafayette Park ](https://www.expedia.co.uk/Tallahassee-Lafayette-Park.dx641416512941260800) - [Visit Lake Bradford -Cascade Lake ](https://www.expedia.co.uk/Tallahassee-Lake-Bradford-Cascade-Lake.dx553248635976481335) - [Visit Tallahassee ](https://www.expedia.co.uk/Tallahassee.dx6048214) - [Visit White Springs ](https://www.expedia.co.uk/White-Springs.dx183127) - [Car hire in Avis Islamic College Street ](https://www.expedia.co.uk/Avis-at-Islamic-College-Street-Amman-JOR.v86458.Car-Rental-Guide-Location) - [Rental cars Tallahassee Intl. airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Tallahassee-Intl.d4738132.Car-Hire-Guide) - [Firefly Cyprus Rental Cars in Dog Island ](https://www.expedia.co.uk/Firefly-Cyprus-Car-Rentals-In-Dog-Island.d553248633992414405-c1108.Car-Rental-Guide-Suppliers) - [Fox Rental Cars Rental Cars in Dog Island ](https://www.expedia.co.uk/Fox-Rental-Cars-Car-Rentals-In-Dog-Island.d553248633992414405-c19.Car-Rental-Guide-Suppliers) - [Kk Leisure Rental Cars in Dog Island ](https://www.expedia.co.uk/KK-Leisure-Car-Rentals-In-Dog-Island.d553248633992414405-c1133.Car-Rental-Guide-Suppliers) - [Mex Rent A Car Rental Cars in Dog Island ](https://www.expedia.co.uk/Mex-Rent-A-Car-Car-Rentals-In-Dog-Island.d553248633992414405-c1084.Car-Rental-Guide-Suppliers) - [Midway Car Rental Rental Cars in Dog Island ](https://www.expedia.co.uk/Midway-Car-Rental-Car-Rentals-In-Dog-Island.d553248633992414405-c27.Car-Rental-Guide-Suppliers) - [Owners Rental Cars in Dog Island ](https://www.expedia.co.uk/Owners-Car-Rentals-In-Dog-Island.d553248633992414405-c1066.Car-Rental-Guide-Suppliers) - [Alligator Point Holiday Rentals ](https://www.expedia.co.uk/Alligator-Point-Holiday-Rentals.d553248635975849030.Travel-Guide-HolidayRentals) - [Dog Island Holiday Rentals ](https://www.expedia.co.uk/Dog-Island-Holiday-Rentals.d553248633992414405.Travel-Guide-HolidayRentals) - [Lanark Village Holiday Rentals ](https://www.expedia.co.uk/Lanark-Village-Holiday-Rentals.d553248635975876519.Travel-Guide-HolidayRentals) - Cities near Panacea - Places of interest [Carrabelle](https://expedia.co.uk/Carrabelle.dx86458)[Crawfordville](https://expedia.co.uk/Crawfordville.dx183090)[Sopchoppy](https://expedia.co.uk/Sopchoppy.dx6355340) - [Bald Point State Park ](https://expedia.co.uk/Bald-Point-State-Park-Panacea.d553248621532654045.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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