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Check prices for these dates

In two weeks
27 Nov - 29 Nov
In two months
8 Jan - 10 Jan
In three months
5 Feb - 7 Feb
In four months
5 Mar - 7 Mar

Our top choices for Panacea holiday rentals

A wooden bench in a natural setting with a lake and trees in the background.

1. Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
The price is £129
includes taxes & fees
18 Nov - 19 Nov
Queen Kitchenette by the Bay #13
A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

2. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
Panacea
9.8 out of 10, Exceptional, (28 reviews)
"Great place to stay while fishing"
United States
Benjamin S.
The price is £227
includes taxes & fees
15 Nov - 16 Nov
Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
A cozy living room with a brown leather sofa, a dining table set with plates, and a view of the sea through large windows.

3. romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
The price is £229
includes taxes & fees
16 Nov - 17 Nov
romantic get away for 2 right on the Ochlockonee river
A covered outdoor area with a wooden deck, white furniture, and a view of the water.

4. Tiny Tides Waterfront Cottage

Tiny Tides Waterfront Cottage
Panacea
10.0 out of 10, Exceptional, (15 reviews)
"What a perfect escape! We thoroughly enjoyed our stay at Tiny Tides. The cozy, comfortable vibe, the peaceful location, and the easy access to everything made our trip truly special. We had a fantastic time and will definitely be back soon!"
United States
Jason W.
The price is £275
includes taxes & fees
17 Nov - 18 Nov
Tiny Tides Waterfront Cottage
A wooden bench in a natural setting with a lake and trees in the background.

5. 09) Queen Kitchenette by the Bay

09) Queen Kitchenette by the Bay
Panacea
The price is £129
includes taxes & fees
18 Nov - 19 Nov
09) Queen Kitchenette by the Bay
A wooden bench in a natural setting with a lake and trees in the background.

6. Perfect Panacea 1 Bedroom Apt, #2

Perfect Panacea 1 Bedroom Apt, #2
Panacea
The price is £129
includes taxes & fees
15 Nov - 16 Nov
Perfect Panacea 1 Bedroom Apt, #2
A tree silhouetted against a sunset sky, a body of water, and a snowy landscape.

7. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
The price is £129
includes taxes & fees
15 Nov - 16 Nov
Cozy Panacea Retreat #3 (King)
A dock extending into a body of water with a covered structure at the end.

8. Private beach winter escape on the bay with fishing and kayaks

Private beach winter escape on the bay with fishing and kayaks
Panacea
10.0 out of 10, Exceptional, (5 reviews)
"Had a great stay! We would book here again."
United States
Ashley D.
The price is £352
includes taxes & fees
14 Nov - 15 Nov
Private beach winter escape on the bay with fishing and kayaks
A wooden bench in a natural setting with a lake and trees in the background.

9. Queen Kitchenette by the Bay #16

Queen Kitchenette by the Bay #16
Panacea
10.0 out of 10, Exceptional, (1 review)
The price is £129
includes taxes & fees
16 Nov - 17 Nov
Queen Kitchenette by the Bay #16
A wooden bench in a natural setting with a lake and trees in the background.

10. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
The price is £129
includes taxes & fees
15 Nov - 16 Nov
Cozy Panacea Retreat #3 (King)
A wooden bench in a natural setting with a lake and trees in the background.

11. Queen Kitchenette by the Bay #10

Queen Kitchenette by the Bay #10
Panacea
The price is £129
includes taxes & fees
15 Nov - 16 Nov
Queen Kitchenette by the Bay #10
A wooden bench in a natural setting with a lake and trees in the background.

12. Queen Kitchenette by the Bay #15

Queen Kitchenette by the Bay #15
Panacea
The price is £123
includes taxes & fees
17 Nov - 18 Nov
Queen Kitchenette by the Bay #15
A wooden bench in a natural setting with a lake and trees in the background.

13. Queen Kitchenette by the Bay #11

Queen Kitchenette by the Bay #11
Panacea
The price is £123
includes taxes & fees
17 Nov - 18 Nov
Queen Kitchenette by the Bay #11
A wooden bench in a natural setting with a lake and trees in the background.

14. Queen Kitchenette by the Bay #14

Queen Kitchenette by the Bay #14
Panacea
The price is £129
includes taxes & fees
16 Nov - 17 Nov
Queen Kitchenette by the Bay #14
A wooden bench in a natural setting with a lake and trees in the background.

15. Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
The price is £123
includes taxes & fees
17 Nov - 18 Nov
Cozy Panacea Retreat #7 (King)
A porch with wicker chairs and a small table, overlooking a lake and trees.

16. Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
United States
Scott A.
The price is £339
includes taxes & fees
13 Nov - 14 Nov
Point & Paddle Waterfront Retreat @Alligator Point
A wooden bench in a natural setting with a lake and trees in the background.

17. Queen Kitchenette by the Bay #8

Queen Kitchenette by the Bay #8
Panacea
The price is £160
includes taxes & fees
15 Nov - 16 Nov
Queen Kitchenette by the Bay #8
A wooden deck with wicker chairs and a long table, overlooking a beach and ocean.

18. The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida
Panacea
10.0 out of 10, Exceptional, (101 reviews)
"Wonderful place on the beach. My sister and I had a great time here. I especially love that the beach is dog-friendly!"
United States
Lisa R.
The price is £478
includes taxes & fees
14 Nov - 15 Nov
The Best Beach-Front House “Get-A-Way” in Florida
Two twin beds with matching headboards, a nightstand with a lamp, a framed picture on the wall, and an American flag.

19. Panacea Cozy Retreat #4 (DQ)

Panacea Cozy Retreat #4 (DQ)
Panacea
The price is £161
includes taxes & fees
18 Nov - 19 Nov
Panacea Cozy Retreat #4 (DQ)
Two twin beds with matching headboards, a nightstand with a lamp, a framed picture on the wall, and an American flag.

20. Panacea Cozy Retreat #6 (DQ)

Panacea Cozy Retreat #6 (DQ)
Panacea
The price is £161
includes taxes & fees
15 Nov - 16 Nov
Panacea Cozy Retreat #6 (DQ)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find holiday rentals that suit your style

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Top Panacea Hotel Reviews

A fountain with a dolphin statue in a courtyard, surrounded by buildings with arched windows and a pool with blue mosaic tiles.
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville

10/10 Excellent

Impressed with the cleanliness and helpfulness of the staff. Wish we could have stayed for another night.
United Kingdom
Stacey
Reviewed March 20, 2024
Best Western Wakulla Inn & Suites

Find out more about Panacea

Everything you need to know about Panacea holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panacea holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panacea holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panacea holiday rentals we have selected for you start as low as £122 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find holiday rentals in Panacea?

Yes, there are holiday rentals in Panacea close to Gulf Specimen Public Aquarum, or you can select a more secluded option if you're looking for a relaxing stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best holiday rentals that Panacea has to offer?

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.: This highly rated holiday home rental in Panacea is located on the beach, and has an outdoor pool, a balcony and air conditioning to put you at ease in your new surroundings. It has 6 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. Some other homes for rent in Panacea include Your Fall Escape: FSU Football & Scalloping and Coastal Getaway on canal-steps to the beach.

How many holiday rentals are there in Panacea?

Choose from 177 Expedia holiday rentals in Panacea for a memorable holiday.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Wilson Beach are other places worth a visit.

What’s a holiday rental in Panacea like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Panacea. Holiday rentals offer amenities such as WiFi and washers and dryers to help you enjoy your stay. If you're concerned about a clean environment, a holiday rental can provide a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular choice for family trips or small group gatherings.