Title: Holiday Rentals La Mesa from £115: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Hotels in La Mesa](https://expedia.co.uk/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[La Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesa.d8484.Car-Hire-Guide)[La Mesa Holidays](https://expedia.co.uk/La-Mesa.d8484.Holidays-City-Breaks) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in La Mesa - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [22 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2025-11-22&endDate=2025-11-23&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Nov - 24 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2025-11-23&endDate=2025-11-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2025-11-28&endDate=2025-11-30&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2025-12-05&endDate=2025-12-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Holiday Rentals in La Mesa ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/d0f0db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/112e5b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/w2000h1293x0y90-00acac65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter Downtown San Diego 9.2/10 Wonderful (565) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £115 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/0f983451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/52541661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/26d61c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/10234b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Gaslamp Quarter San Diego Downtown San Diego 8.0/10 Very good (150) "Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris [](https://www.expedia.co.uk/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/176e7c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Non Smoking, Kitchenette | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/410d9c05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/22f9394f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/90fc758b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coronado Beach Resort Historic Downtown Coronado 9.0/10 Wonderful (743) "Friendly, personable staff, clean room, easy access parking, would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £151 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/6177273a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/7ec33e9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/42520090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Non Smoking, Kitchenette | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/76a5ddfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wave Crest Resort Del Mar 9.2/10 Wonderful (141) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin £188 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/79e8f033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bayview Condo - 2BR/3BA - Bunk Bed & Sofa Bed | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/48c0125d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills Middletown 9.6/10 Exceptional (101) "Staff was very attentive and the building was wonderful. The only reason I didn't rate 5 stars is it can be quite loud being across the street from the airport. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £135 includes taxes & fees 18 Dec - 19 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/735d03a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/72346346.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/5eb9df30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/363be3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly Renovated Serene San Diego Retreat: Hot Tub Spring Valley £433 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Spring-Valley-Hotels-Spacious-Spring-Valley-Home-W-Fenced-Yard-Grill.h104953896.Hotel-Information) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/041763bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/4bd4f5cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/w2999h2000x1y0-3e37e88c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/3d2a390c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna Downtown San Diego £296 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-NEW-Upscale-Downtown-San-Diego-Stay-Queen-Bed-Pool-Sauna.h118267698.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/16000000/15260000/15252100/15252005/a963a1ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Townhome, 2 Bedrooms, 2 Queens and 1 Sofa Bed | Private kitchen](https://images.trvl-media.com/lodging/16000000/15260000/15252100/15252005/d0edf8fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15260000/15252100/15252005/4f942a8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Townhome, 2 Bedrooms, 2 Queens and 1 Sofa Bed | Living area](https://images.trvl-media.com/lodging/16000000/15260000/15252100/15252005/847f46e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 Bedroom Townhome 2 Mins. to the Beach Mission Beach 6.4/10 (6) "We showed up only to find that our place had been taken by someone else. It was at night and we had no car and no where to stay. We paid online and were told sorry about the inconvinience but there were no other properties available. We were in an alley with our luggage to begin what we thought was our weekend of fun in San Diego. It was such a bad experience and a stressful one too. We ended up finding 1 room with 2 beds for four adult non couple males. We were charges more than the town hime... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edgar £603 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-2-Bedroom-Townhome-2-Mins-To-The-Beach.h15252005.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, 2 Bedrooms | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/ad340e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/7d574065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms, Bay View (QueenBed) | Balcony view](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/f6cadddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Little Italy San Diego Downtown San Diego 9.6/10 Exceptional (345) "Beautiful rooms, super clean and very responsive and nice staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ivona £221 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/b28adcb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/9da3dfd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/0eff3773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/8ecd0448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View! Village of La Jolla £793 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/La-Jolla-Hotels-Walk-To-La-Jolla-Cove-Dtwn-Cottage-W-Ocean-View.h115485967.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-06&endDate=2025-12-07®ionId=8484&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=VR_BF_PROMO_8484) ## Find holiday rentals that suit your style Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=VACATION_HOME) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=VILLA) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=CONDO) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=COTTAGE) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=CABIN) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-23&d2=2026-02-23&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Holiday-Rentals.d8484.Travel-Guide-HolidayRentals)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Holiday-Rentals.d8484.Travel-Guide-HolidayRentals) ## Top La Mesa Hotel Reviews ![Comfort Inn Sea World Area](https://images.trvl-media.com/lodging/1000000/550000/544700/544662/44f458a2_y.jpg) ### Comfort Inn Sea World Area 10/10 Excellent "Yes" [](https://expedia.co.uk/San-Diego-Hotels-Comfort-Inn-Sea-World-Area.h544662.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Loved this hotel!" [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "Would recommend " [](https://expedia.co.uk/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Amazing bay view. Everything is near by. Very clean and staff was very friendly and helpful " [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Great hot tub" [](https://expedia.co.uk/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "All clean, easy check in. Restaurant had good food. " [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Everything! " [](https://expedia.co.uk/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Nice clean room, super comfortable and really nice location if you are going out on a fishing trip out of Seaforth Marina. Check in staff were awesome, I really enjoyed the process. The price point was awesome too. " [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Nice cookies! Good clean rooms." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ## Find out more about La Mesa **Everything you need to know about** **La Mesa** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesa holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesa holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **La Mesa holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in La Mesa. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A La Mesa holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of La Mesa holiday rentals we have selected for you start as low as £115 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on La Mesa rentals** At Expedia, we put the best La Mesa holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top La Mesa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesa holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in La Mesa ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) - [Villas in La Mesa](https://expedia.co.uk/La-Mesa-Villas.d8484-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in La Mesa](https://expedia.co.uk/La-Mesa-Guest-Houses.d8484-aaGuestHouses.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there holiday rentals in La Mesa? > Yes, there are holiday rentals in La Mesa close to Computer Museum of America, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip. ### What are some of the best holiday rentals that La Mesa has to offer? > [Casa Del Cerro](https://www.expedia.co.uk/San-Diego-Hotels-Casa-Del-Cerro.h95882162.Hotel-Information): This holiday home rental outside of La Mesa offers a garden, a selection of games and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of Access to hot tub in this rental home to help you unwind. ### How many holiday rentals are there in La Mesa? > With 111 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay. ### What can I see and do in La Mesa? > Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Petco Park and Port of San Diego. ### What are holiday rentals like in La Mesa? > Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering. ### Expedia's Latest Trends Hotels - [Hotels in Big Sur](https://expedia.co.uk/Big-Sur-Hotels.d177505.Travel-Guide-Hotels) - [Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6666.Travel-Guide-Hotels) - [Hotels in Carmel](https://expedia.co.uk/Carmel-Hotels.d6026.Travel-Guide-Hotels) - [Hotels in San Diego](https://expedia.co.uk/San-Diego-Hotels.d3073.Travel-Guide-Hotels) - [Hotels in San Jose](https://expedia.co.uk/San-Jose-Hotels.d602703.Travel-Guide-Hotels) - [Hotels in Huntington Beach](https://expedia.co.uk/Huntington-Beach-Hotels.d8165.Travel-Guide-Hotels) - [Hotels in Santa Barbara](https://expedia.co.uk/Santa-Barbara-Hotels.d602277.Travel-Guide-Hotels) - [Hotels in Palm Springs](https://expedia.co.uk/Palm-Springs-Hotels.d180676.Travel-Guide-Hotels) - [Hotels in Anaheim](https://expedia.co.uk/Anaheim-Hotels.d5921.Travel-Guide-Hotels) - [Hotels in Yosemite National Park](https://expedia.co.uk/Yosemite-National-Park-Hotels.d183032.Travel-Guide-Hotels) - [Hotels in Monterey](https://expedia.co.uk/Monterey-Hotels.d180045.Travel-Guide-Hotels) - [Hotels in Death Valley](https://expedia.co.uk/Death-Valley-Hotels.d54985.Travel-Guide-Hotels) - [Hotels in South Lake Tahoe](https://expedia.co.uk/South-Lake-Tahoe-Hotels.d10150.Travel-Guide-Hotels) Flights - [Flights to Death Valley](https://expedia.co.uk/Cheap-Flights-To-Death-Valley.d54985.Travel-Guide-Flights) - [Flights to Tahoe City](https://expedia.co.uk/Cheap-Flights-To-Tahoe-City.d180041.Travel-Guide-Flights) - [Flights to Cupertino](https://expedia.co.uk/Cheap-Flights-To-Cupertino.d6494.Travel-Guide-Flights) - [Flights to Fairfield](https://expedia.co.uk/Cheap-Flights-To-Fairfield.d6055407.Travel-Guide-Flights) - [Flights to San Jose](https://expedia.co.uk/Cheap-Flights-To-San-Jose.d602703.Travel-Guide-Flights) - [Flights to Coachella](https://expedia.co.uk/Cheap-Flights-To-Coachella.d6287789.Travel-Guide-Flights) - [Flights to Anaheim](https://expedia.co.uk/Cheap-Flights-To-Anaheim.d5921.Travel-Guide-Flights) - [Flights to Palm Springs](https://expedia.co.uk/Cheap-Flights-To-Palm-Springs.d180676.Travel-Guide-Flights) - [Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights) - [Flights to Santa Barbara](https://expedia.co.uk/Cheap-Flights-To-Santa-Barbara.d602277.Travel-Guide-Flights) Cars - [Car hire in San Jose](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Jose.d602703.Car-Hire-Guide) - [Car hire in San Diego](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego.d3073.Car-Hire-Guide) - [Car hire in Palm Springs](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Palm-Springs.d180676.Car-Hire-Guide) Activities - [Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities) - [Things to do in Santa Barbara](https://expedia.co.uk/Things-To-Do-In-Santa-Barbara.d602277.Travel-Guide-Activities) Packages - [Palm Springs Holidays](https://expedia.co.uk/Palm-Springs.d180676.Holidays-City-Breaks) General - [Visit Palm Springs](https://expedia.co.uk/Palm-Springs.dx180676) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)