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Our top choices for La Mesa holiday rentals

1. Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden

Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden
Mount Helix
10.0 out of 10, Exceptional, (1 review)
"We really enjoyed staying here. Clean and roomy and has everything you’d need. "
United States
Linda R.
The price is £267
includes taxes & fees
1 Sept - 2 Sept
Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden

2. Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH

Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH
La Mesa
10.0 out of 10, Exceptional, (1 review)
The price is £296
includes taxes & fees
9 Sept - 10 Sept
Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH

3. Private Casita • No Extra Fees • Spa • Beach • AC

Private Casita • No Extra Fees • Spa • Beach • AC
La Mesa
The price is £148
includes taxes & fees
24 Aug - 25 Aug
Private Casita • No Extra Fees • Spa • Beach • AC

4. King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth

King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth
La Mesa
The price is £290
includes taxes & fees
31 Aug - 1 Sept
King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth

5. Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access

Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
La Mesa
9.0 out of 10, Wonderful, (10 reviews)
"We had a wonderful stay! The home is lovely, clean and exactly as described. Jonathan is very nice and easy to communicate with. We loved staying here to celebrate our son’s graduation from SDSU!"
United States
Anonymous traveller
The price is £351
includes taxes & fees
9 Sept - 10 Sept
Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access

6. Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom

Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom
La Mesa
The price is £274
includes taxes & fees
30 Aug - 31 Aug
Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom

7. Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
3.0 star property
Windsor Hills
The price is £590
includes taxes & fees
25 Aug - 26 Aug
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

8. Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
Windsor Hills
8.8 out of 10, Excellent, (16 reviews)
"We really enjoyed the deck the weather wasn't pool cooperate The home was beautiful "
United States
Robert N.
The price is £610
includes taxes & fees
25 Aug - 26 Aug
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

9. Queen Bed Non-Smoking

Queen Bed Non-Smoking
San Diego CA
10.0 out of 10, Exceptional, (100 reviews)
"Just right for sleeping after sightseeing all day, glad I chose this place over others nearby based on price/availability combo!"
United States
Anonymous traveller
The price is £50
includes taxes & fees
24 Aug - 25 Aug
Queen Bed Non-Smoking

10. Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry

Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry
Mid-City
10.0 out of 10, Exceptional, (4 reviews)
"Our stay was lovely at Neric's place. Nice decor, clean, comfortable, & quiet. The AC worked well to keep the home at the perfect temp for us. We will stay here again!"
United States
Katherine S.
The price is £125
includes taxes & fees
9 Sept - 10 Sept
Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry

11. Lake Murray 3BR Retreat with AC and Skylight

Lake Murray 3BR Retreat with AC and Skylight
La Mesa
10.0 out of 10, Exceptional, (15 reviews)
"Our stay was fantastic and it had everything we need for our 1 week stay. I recommend this location. "
United States
Rosa C.
The price is £221
includes taxes & fees
8 Sept - 9 Sept
Lake Murray 3BR Retreat with AC and Skylight

12. Cozy Private Studio in El Cajon

Cozy Private Studio in El Cajon
Mount Helix
9.0 out of 10, Wonderful, (27 reviews)
"It was a great plead to stay"
United States
Simon
The price is £111
includes taxes & fees
24 Aug - 25 Aug
Cozy Private Studio in El Cajon

13. 'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
Encanto
8.8 out of 10, Excellent, (39 reviews)
"Beds were very comfortable."
United States
Paula
The price is £187
includes taxes & fees
25 Aug - 26 Aug
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

14. La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.0 out of 10, Wonderful, (9 reviews)
"The property was well located for us. "
United States
Ann D.
The price is £415
includes taxes & fees
1 Sept - 2 Sept
La Mesa Family Retreat - 20 minutes to Beaches & More!

15. La Casita Guest House, private fenced yard & with heat and AC, pet friendly

La Casita Guest House, private fenced yard & with heat and AC, pet friendly
Mount Helix
9.8 out of 10, Exceptional, (13 reviews)
"Host and amenities were both very nice. "
United States
Juergen S.
The price is £237
includes taxes & fees
8 Sept - 9 Sept
La Casita Guest House, private fenced yard & with heat and AC, pet friendly

16. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (438 reviews)
"Staff were wonderful. Great location."
United States
Benjamin
The price is £78
includes taxes & fees
1 Sept - 2 Sept
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

17. Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.8 out of 10, Excellent, (11 reviews)
"The place was as advertised. Comfortable and good privacy in an area that at first glance, didn’t seem like it would have any"
United States
Steve F.
The price is £224
includes taxes & fees
24 Aug - 25 Aug
Cozy 2-Bedroom Cottage Near Balboa Park

18. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,166 reviews)
"Place is clean and beautiful, grear location."
United States
Mabel
The price is £129
includes taxes & fees
7 Sept - 8 Sept
Marriott Vacation Club®, San Diego

19. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (191 reviews)
"Enjoyed my stay! Clean spacious room and friendly staff."
United States
omokayode
The price is £135
includes taxes & fees
24 Aug - 25 Aug
City24 Hotel Little Italy Mission Hills

20. Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (106 reviews)
"Great location."
United States
James R.
The price is £230
includes taxes & fees
1 Sept - 2 Sept
Beautiful Normal Heights Living
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Find out more about La Mesa

Everything you need to know about La Mesa holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesa holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesa holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

La Mesa holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in La Mesa. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A La Mesa holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of La Mesa holiday rentals we have selected for you start as low as £50 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on La Mesa rentals

At Expedia, we put the best La Mesa holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top La Mesa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesa holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Explore a world of travel with Expedia

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to La Mesa Memorial Fine Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

What are some of the best holiday rentals that La Mesa has to offer?

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC: This holiday home rental outside of La Mesa is equipped with a BBQ, air conditioning and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family.

How many holiday rentals are there in La Mesa?

With 63 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Petco Park and Mission Bay.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.