La Mesa Holidays from £1,158

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your La Mesa Holiday

Lock in a La Mesa holiday package that includes everything you need and nothing you don't. Good for gift and craft shops, dining and nightlife, think about staying in the neighbourhood of Downtown San Diego. The Magnolia, Santee Lakes and Grossmont College are just a few of the attractions you'll want to explore during your trip to La Mesa. Browse Expedia's wide range of travel options and start organising your perfect holiday to La Mesa today.

Top La Mesa Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Z

Hotel Z

3 out of 5
Downtown San Diego
Price was £1,534, price is now £1,158 per person
£1,158
per person
15 Jan - 22 Jan
found 9 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9.2/10 Wonderful! (1,212 reviews)

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
Mission Bay
Price was £1,822, price is now £1,413 per person
£1,413
per person
15 Jan - 22 Jan
found 9 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
8.8/10 Excellent! (2,946 reviews)
Had a great time

Reviewed on 12 Nov 2026

El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island

3.5 out of 5
Historic Downtown Coronado
Price was £1,644, price is now £1,281 per person
£1,281
per person
15 Jan - 22 Jan
found 9 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
8.8/10 Excellent! (1,007 reviews)

The Wayfarer San Diego

The Wayfarer San Diego

4 out of 5
Mission Beach
Price was £1,807, price is now £1,419 per person
£1,419
per person
15 Jan - 22 Jan
found 9 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9.4/10 Exceptional! (1,957 reviews)
Excellent location! Amazing ocean views. Lots of great restaurants and shops within walking distance. Clean, comfortable and quiet rooms. Friendly and helpful staff. Pool area has a wonderful view of the ocean, day beds, fire pit for those chilly evenings, relaxing hot tub. There's also a great little café with craft coffee, muffins, breakfast sandwiches to start the day off right. Wide selection of beverages. Beach rentals such as chairs, umbrellas, boogie boards. Bikes to explore the boardwalk. Fall asleep with the balcony door open to hear the waves crash. Highly recommend The Wayfarer for a wonderful, relaxing escape.

Reviewed on 12 Nov 2026

The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
Mission Bay
Price was £1,497, price is now £1,206 per person
£1,206
per person
15 Jan - 22 Jan
found 9 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9/10 Wonderful! (4,484 reviews)

Where to stay in La Mesa

Find the best La Mesa areas and neighborhoods for the activities you enjoy most. Learn more about La Mesa
A town with a mountain in the background, a clear sky, and scattered clouds.

Casa de Oro-Mount Helix

1 out of top 10 points of interest in this area

While Casa de Oro-Mount Helix may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Mount Helix Park and The Magnolia.

Find hotels in Casa de Oro-Mount Helix

La Mesa Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)
Population
60,100
Max Temp Winter
18ºC
Max Temp Summer
27ºC
Top Sights
San Diego Zoo, Coronado Beach and Old Town San Diego State Park

Top hotels in La Mesa

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
The price is £148 per night from 22 Nov to 23 Nov
£148
22 Nov - 23 Nov
includes taxes & fees
8.4/10 Very good! (6,370 reviews)
"The Wyndham San Diego Bayside is very conveniently located. The staff were very welcoming and helpful. The rooms were spacious and comfortable. We loved the walkability to the cruise pier, Little Italy, Seaport Village and transit was close by to get to many points of interest. Highly recommend this ..."

Reviewed on 12 Nov 2026

Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is £178 per night from 22 Nov to 23 Nov
£178
22 Nov - 23 Nov
includes taxes & fees
Hard Rock Hotel San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
The price is £74 per night from 13 Dec to 14 Dec
£74
13 Dec - 14 Dec
includes taxes & fees
8.4/10 Very good! (3,053 reviews)
"Great place. Clean and friendly staff"

Reviewed on 11 Nov 2026

Handlery Hotel
See all 8,558 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular La Mesa attractions

Mount Helix Park

7.4/10 (59 reviews)
Perched atop a hill, Mount Helix Park offers stunning 360-degree views of San Diego County and the Pacific Ocean. Explore the serene trails or attend a performance in the historic 1,600-seat open-air amphitheatre.
See properties

What to do in La Mesa

San Diego City Lights Night Tour

San Diego City Lights Night Tour

£33
per adult
94% of travellers recommend
San Diego City Lights Night Tour
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

£8
per adult
San Diego: Luggage Storage in Marina
See all activities in La Mesa

Frequently asked questions

How much does a La Mesa travel package cost?
We make it simple to travel somewhere new, with La Mesa travel packages starting from as little as £1,158. You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few tours and experiences to your travel itinerary?
If I'm not able to travel, can I cancel my La Mesa travel package?
You can. We get that even the best-laid plans can go awry, so we're happy to help if you have to make changes to your La Mesa travel package. It may be possible to change or cancel your itinerary at no cost if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for further information. Also, be sure to check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to La Mesa?
Bundle, bundle, bundle. Hotels, rental cars and flights — combine whatever you need into a La Mesa travel package and save. Score even more discounts when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to tailor your holiday your way. We offer more than 550 air carriers and 1,000,000 hotels throughout the world, so that everyone has an opportunity to travel and fulfil those holiday dreams.
Does Expedia offer Book Now, Pay Later La Mesa holidays?
Expedia has partnered with online lender Klarna to make booking your next getaway easier on your budget. Paying in instalments means you can spread the costs of your next big holiday, leaving you with more cash to play with while you're travelling. Klarna has several payment plans to choose from, so you're sure to find one that fits your budget. Take a look at these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month is what works best for you, Klarna offers just that! Paying in convenient monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Then select this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the total upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan with Klarna.

Where should I stay in La Mesa?
A trip to La Mesa isn't complete without checking out San Diego State University, Mount Helix Park and The Salvation Army Kroc Centre. Stay close to these popular attractions and make sightseeing easy.
What are the top hotels in La Mesa?
Many people visiting La Mesa often stay in Mount Helix. Holiday Inn La Mesa, an IHG Hotel and Heritage Inn La Mesa are well-known options in this neighbourhood. But it's not the only interesting place in town! Windsor Hills is also a fantastic area and where you'll find Holiday Inn La Mesa, an IHG Hotel and Heritage Inn La Mesa.
How far in advance should I book my La Mesa holiday?
It can be difficult to know exactly when the best time is to book your La Mesa trip. But usually the earlier you book, the more affordable the prices. Sometimes, you can secure your flights and hotels up to 12 months prior to departure. If you're hoping for a last-minute getaway, no need to stress! There are terrific deals posted on Expedia every day.
What does an Expedia La Mesa travel package include?
Rental cars, flights and hotels, or any combination of them — it's your choice. Whether you're exploring La Mesa with the entire family or travelling solo, there's a bundle to match your style and budget. Once you've made your booking, why not add on a few activities?
What should I know before booking a La Mesa travel package?
Whether it's relaxation or adventure you're chasing, a La Mesa travel package lets you plan your escape your way. Plus, you'll get access to great discounts when you combine your hotel with your flights and rental car. The more you bundle, the more you'll save!
Can I choose my airline with a La Mesa Expedia travel package?
Most definitely. Expedia has more than 550 partner airlines to pick from all over the world. With so much choice, finding the perfect carrier to whisk you off to La Mesa shouldn't be hard.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.