Title: Top Hotels in Santa Cruz - Compare Santa Cruz Hotels | Expedia.co.uk [Holiday Rentals in Santa Cruz](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations)[Santa Cruz Flights](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Santa Cruz Car Hire](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Car-Hire-Destinations)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6297178.Holidays-City-Breaks) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best Santa Cruz Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Santa Cruz Accommodation: Most Popular Cities to Stay ![San Lorenzo Cathedral showing a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/115000/115563-Santa-Cruz.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) ![](https://mediaim.expedia.com/destination/2/06496d3cec9b6cad4a738ddeb6156d1c.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Samaipata [](https://expedia.co.uk/Samaipata-Hotels.d6200976.Travel-Guide-Hotels) ![](https://mediaim.expedia.com/destination/2/101c2fd6556e96d089a24b3e99f984cc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Javier [](https://expedia.co.uk/San-Javier-Hotels.d6350629.Travel-Guide-Hotels) ## Check prices for these dates Tonight [18 Dec - 19 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/9bf66d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/c96e3d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/7d01dcfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) Santa Cruz 9.0/10 Wonderful (347) "Great spacious property with nice pool!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas £91 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/f930f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/c82fd616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/4f7a4f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Santa Cruz de la Sierra Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) Santa Cruz 9.0/10 Wonderful (211) "Great hotel, food and location albeit a little expensive " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo £83 16 Jan - 17 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/03d4f9ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/3efb7ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/f871875e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ibis Santa Cruz DE LA Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) Santa Cruz 9.6/10 Exceptional (75) "Great Spot" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £31 19 Dec - 20 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/0ffe84ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, swim-up bar, poolside bar](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/96ef3d87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camino Real Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) Santa Cruz 8.8/10 Excellent (407) "The parrots. Unique" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan P £134 17 Jan - 18 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/cd898aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/e63a6005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room, 1 King Bed, Pool View | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/07bd498f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sun Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) Santa Cruz 8.4/10 Very good (331) "Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter £67 19 Dec - 20 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/97b153fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/b24e36f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/a6a85fc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cortez [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) Santa Cruz 9.2/10 Wonderful (123) "The staff and property are second to none! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia £92 19 Dec - 20 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/864143db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/1777fe4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/3a211a94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/fb4d1503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Santa Cruz De La Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) Santa Cruz 9.2/10 Wonderful (104) "Luxurious hotel,very chic and beautiful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristhian £74 16 Jan - 17 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/63408901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/7d4fe05c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, Hot Tub, City View | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/2a14b8e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL OSHO [](https://www.expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) Santa Cruz 9.2/10 Wonderful (34) "Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £38 19 Dec - 20 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/794bff22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/34d33eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/e77454e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) Santa Cruz 9.2/10 Wonderful (256) "Nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Narciso Lorenzo £55 17 Jan - 18 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment, 2 Bedrooms | Private kitchen | Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/938b051b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment, Terrace | Private kitchen | Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/cb07702a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/b0eabde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) Santa Cruz 8.6/10 Excellent (93) "Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/f5f73e6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/eca5a1cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/6fe72ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chairú Eco Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) Santa Cruz 9.6/10 Exceptional (48) "Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/6f72135a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 2 Bedrooms, Non Smoking | Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/8d7975b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/483404d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) Santa Cruz 9.2/10 Wonderful (145) "Nice stay with good service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jianyuan £74 30 Dec - 31 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/12ef5e8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Apartment, 1 King Bed with Sofa bed, Terrace | Premium bedding, down duvets, Tempur-Pedic beds, in-room safe](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/72a81d70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/cbf735a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/f316b83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) Santa Cruz 9.0/10 Wonderful (81) "Good price, great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £29 21 Dec - 22 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/d39bec98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/d2cd08da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/237e7aad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/6b27e04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swissôtel Santa Cruz De La Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) Santa Cruz 9.2/10 Wonderful (81) "Beautiful hotel" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Joanna £88 17 Jan - 18 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/fd3e0846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Minibar, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/7c99de6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/ba8e1404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/20d0c7ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Delfines Collection Hotel By Mercure [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) Santa Cruz 9.0/10 Wonderful (71) "Excellent place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luisa £35 26 Dec - 27 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/a92c6796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/7b4c5ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/a0ed71e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lido Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) Santa Cruz 9.0/10 Wonderful (30) "Very helpful and nice staff. Quiet location. near the central plaza. Great value " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) David £34 19 Dec - 20 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/a7124411.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/c3eb7cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/406a6473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/159b6eba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alfonsina Hotel Boutique by Inboccaluppo [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Inboccalupo-The-Hotel-Boutique.h10202755.Hotel-Information) Santa Cruz 9.4/10 Exceptional (40) "Love it. Will stay again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan £79 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Inboccalupo-The-Hotel-Boutique.h10202755.Hotel-Information) ![Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/4810f028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/0494663f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/0132556f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel LP Santa Cruz Centro [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information) Santa Cruz 8.0/10 Very good (281) "Clean, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Giovanna [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/47e3b432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/5b173b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/331f956e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Room, 3 Single Beds | Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/734a9fe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel LP Equipetrol [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Equipetrol.h10209582.Hotel-Information) Santa Cruz 8.2/10 Very good (201) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ricardo [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Equipetrol.h10209582.Hotel-Information) ![Triple Room | Free WiFi](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/8e2f8b6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/d2287e81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Free WiFi](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/3886a15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/cc4cd467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Las Américas [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Las-Americas.h112993678.Hotel-Information) Santa Cruz 6.0/10 (1) "O chuveiro foi impossível tomar um.banho de qualidade " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Jean £29 20 Dec - 21 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Las-Americas.h112993678.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=6297178&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Santa Cruz Showing deals for:**26 Dec - 28 Dec** ### Image gallery for HOTEL OSHO ![City view from property](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### HOTEL OSHO Santa Cruz **9.2/10**Wonderful (34 reviews) 10% off £75 for 2 nights, 1 room £38 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=75254801&adults=2) ### Image gallery for Hotel LP Santa Cruz Centro ![Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Hotel LP Santa Cruz Centro Santa Cruz **8.0/10**Very good (281 reviews) 31% off £66 for 2 nights, 1 room £33 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=2761435&adults=2) ### Image gallery for Swissôtel Santa Cruz De La Sierra ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/d39bec98.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Swissôtel Santa Cruz De La Sierra Santa Cruz **9.2/10**Wonderful (81 reviews) Member Price available £210 for 2 nights, 1 room £105 per night [Sign in for Member Price ](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-12-26%26endDate%3D2025-12-28%26selected%3D60335614%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=60335614&adults=2) ### Image gallery for Chairú Eco Hotel ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Chairú Eco Hotel Santa Cruz **9.6/10**Exceptional (48 reviews) 25% off £90 for 2 nights, 1 room £45 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=82389693&adults=2) ### Image gallery for Equipetrol Suites Apart Hotel ![Standard Suite, 2 Single Beds | Hypo-allergenic bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/2b6207d2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Equipetrol Suites Apart Hotel Santa Cruz **8.4/10**Very good (7 reviews) 27% off £49 for 2 nights, 1 room £25 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=90599395&adults=2) ### Image gallery for Apart Hotel Toborochi ![Property grounds](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/4f23dcbf.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Apart Hotel Toborochi Santa Cruz **8.8/10**Excellent (60 reviews) 14% off £96 for 2 nights, 1 room £48 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=10031984&adults=2) ### Image gallery for Hotel Continental Park ![Front of property](https://images.trvl-media.com/lodging/16000000/15250000/15240400/15240320/f9ae8716.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Continental Park Santa Cruz **8.8/10**Excellent (25 reviews) 10% off £103 for 2 nights, 1 room £51 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=15240320&adults=2) ### Image gallery for Ibis Santa Cruz DE LA Sierra ![Restaurant](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Ibis Santa Cruz DE LA Sierra Santa Cruz **9.6/10**Exceptional (75 reviews) Member Price available £63 for 2 nights, 1 room £31 per night [Sign in for Member Price ](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-12-26%26endDate%3D2025-12-28%26selected%3D87138613%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=87138613&adults=2) ### Image gallery for Sun Hotel ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Sun Hotel Santa Cruz **8.4/10**Very good (331 reviews) 25% off £134 for 2 nights, 1 room £67 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=12836211&adults=2) ### Image gallery for Posada Express Fast Check ![Living area](https://images.trvl-media.com/lodging/119000000/118180000/118176600/118176582/322f09bb.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Posada Express Fast Check Santa Cruz **10/10**Exceptional (2 reviews) Member Price available £66 for 2 nights, 1 room £33 per night [Sign in for Member Price ](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-12-26%26endDate%3D2025-12-28%26selected%3D118176582%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=118176582&adults=2) ### Image gallery for Alfonsina Hotel Boutique by Inboccaluppo ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/a7124411.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Alfonsina Hotel Boutique by Inboccaluppo Santa Cruz **9.4/10**Exceptional (40 reviews) 10% off £200 for 2 nights, 1 room £100 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=10202755&adults=2) ### Image gallery for Terranova Suites ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/1f2b7f07.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Terranova Suites Santa Cruz **8.0/10**Very good (90 reviews) 21% off £68 for 2 nights, 1 room £34 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=10950250&adults=2) ### Image gallery for Hotel Cortez ![Reception](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Cortez Santa Cruz **9.2/10**Wonderful (123 reviews) 30% off £160 for 2 nights, 1 room £80 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=13455822&adults=2) ### Image gallery for Hotel BY Armonia SCZ ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/23000000/22220000/22210900/22210823/eca94229.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel BY Armonia SCZ Santa Cruz **8.4/10**Very good (7 reviews) 21% off £96 for 2 nights, 1 room £48 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=22210823&adults=2) ### Image gallery for Hotel LP Equipetrol ![Front of property – evening/night](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/47e3b432.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Hotel LP Equipetrol Santa Cruz **8.2/10**Very good (201 reviews) 38% off £70 for 2 nights, 1 room £35 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=10209582&adults=2) ### Image gallery for Elegant apartment in excellent location ![Interior](https://images.trvl-media.com/lodging/75000000/74790000/74786700/74786630/5f8f407e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Elegant apartment in excellent location Santa Cruz de la Sierra **10/10**Exceptional (1 review) 7% off £79 for 2 nights, 1 apartment £40 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=74786630&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Hotel-Destinations) ## Top Santa Cruz Hotel Reviews ![Hotel LP Santa Cruz Centro](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5_y.jpg) ### Hotel LP Santa Cruz Centro 10/10 Excellent "Clean rooms, well kept facilities and nice staff" [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Well kept. Clean, great staff! " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "spotless" [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Marriott Santa Cruz de la Sierra Hotel](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 10/10 Excellent "Muy bien exelente" [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![HOTEL OSHO](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1_y.jpg) ### HOTEL OSHO 10/10 Excellent "Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!" [](https://expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Everything was absolutely amazing, from the second we arrived to the last day. The service, the room, the property. I always come back to this Hotel time after time. Thank you for all you do to make us feel at home while we’re there " [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Excellent hotel, I willl always used it in this location " [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Clean and close to the malls and restaurants " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Lido Hotel](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f_y.jpg) ### Lido Hotel 10/10 Excellent "The room was clean and comfortable; breakfast was a hot & cold buffet to meet most people’s requirements. It is located a short walk from the main square." [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ## Guide to exploring Santa Cruz ### Top reasons to visit Santa Cruz - **Outdoor Adventures:** Santa Cruz is perfect for outdoor enthusiasts, offering scenic hiking trails and national parks for exploration. - **Cultural Experiences:** Immerse yourself in the rich heritage through stunning cathedrals and iconic landmarks that reflect the local culture. - **Vibrant City Life:** The bustling city centre boasts lively nightlife and stunning views, ideal for a vibrant urban experience. - **Diverse Accommodation:** Enjoy a range of lodging options, from charming bed and breakfasts to well-rated hotels catering to all needs. - **Relaxation Opportunities:** Unwind at resorts and enjoy leisure activities, making it a great destination for families and relaxation seekers. ### Find great hotels in Santa Cruz Santa Cruz, Bolivia, offers a diverse selection of accommodation options, from charming bed and breakfasts to well-rated hotels. Whether you're seeking a family-friendly retreat, a pet-friendly getaway, or a business-themed stay, the city has something to cater to every traveler's needs. Explore the best hotels in Santa Cruz to ensure a comfortable and enjoyable experience while immersing yourself in the vibrant culture of this lively destination. - **[Hotel G: ](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-G.h27664803.Hotel-Information)** Hotel G is a charming 3.5-star hotel that offers a unique pet-friendly experience in the heart of Santa Cruz. This property caters to travellers who wish to enjoy their holiday alongside their furry companions, as it permits dogs and cats onsite. Guests appreciate the welcoming atmosphere and the dedicated amenities for pets, ensuring a comfortable stay for both humans and their four-legged friends. With its cosy rooms and friendly service, Hotel G is an excellent choice for those seeking a relaxed getaway. - **Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel:** Positioned in the vibrant city centre, Los Tajibos is a sophisticated 3.5-star hotel that perfectly blends business functionality with family-friendly comfort. Ideal for corporate travellers, it boasts comprehensive business amenities, including a conference centre and accessible business centre. Families will love the thoughtful features for children, such as a dedicated pool area. The combination of modern design and attentive service makes Los Tajibos a great choice for both work and leisure. - **[Marriott Santa Cruz de la Sierra Hotel: ](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information)** The luxurious 5-star Marriott Santa Cruz de la Sierra Hotel is an upscale haven for travellers seeking elegance and comfort. This property is well-equipped for business and family stays, offering extensive meeting facilities and an accessible business centre. The hotel also caters to families with amenities like complimentary cribs, making it a convenient choice for those travelling with young children. With its high-end services and prime location, the Marriott promises an indulgent stay in Santa Cruz. ### Where to stay in Santa Cruz Santa Cruz, Bolivia, offers a vibrant blend of outdoor adventures and cultural experiences in a tropical setting. Explore the bustling city centre, where stunning views and lively nightlife await. Whether you're seeking a secluded getaway or a budget-friendly family vacation, Santa Cruz provides the perfect backdrop for unforgettable excursions. Discover the warmth of the local atmosphere and immerse yourself in the rich culture that makes this destination truly unique. - **[Santa Cruz: ](https://www.expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)** As the largest city in Bolivia, Santa Cruz is a vibrant hub of commerce and culture. Nestled in the eastern part of the country, it boasts a tropical climate that attracts visitors year-round. The city is ideal for those seeking a mix of urban experiences, with its shopping centres and bustling markets. Highlights include the picturesque piazza square, the lush botanical garden, and the impressive stadium. Whether you're enjoying a family outing or exploring the city's rich offerings, Santa Cruz promises an engaging experience. - **[Samaipata: ](https://www.expedia.co.uk/Samaipata-Hotels.d6200976.Travel-Guide-Hotels)** A short drive from Santa Cruz, Samaipata is a charming town known for its stunning natural landscapes and outdoor adventures. Nestled in the foothills of the Andes, it offers breathtaking scenery and a plethora of hiking trails for the adventurous spirit. The area is steeped in history, with notable archaeological and historic sites that reflect its rich past. Visitors can enjoy local markets and relax in quaint resorts, making it a perfect getaway for those seeking a blend of adventure and tranquillity. - **[Warnes: ](https://www.expedia.co.uk/Warnes-Hotels.d6352296.Travel-Guide-Hotels)** Located conveniently close to Santa Cruz, Warnes is a bustling city that caters to families and business travellers alike. This vibrant area features modern shopping centres and malls, making it a great destination for retail therapy. Notable local attractions include beautiful places of worship and serene botanical gardens, providing a peaceful escape amidst the urban setting. With a welcoming atmosphere and a range of amenities, Warnes is a delightful stop for anyone exploring the region. ### Things to do in Santa Cruz Santa Cruz, Bolivia, is an excellent destination for outdoor enthusiasts and families seeking cultural experiences. Visitors can enjoy a variety of activities, including relaxation at resorts, exploring scenic hiking trails, and catching a film at local cinemas. This vibrant city offers a delightful blend of adventure and leisure, making it an ideal spot for a memorable holiday. **Shopping** In Santa Cruz, you can shop at Ventura Mall, which offers a lively atmosphere with various shops and entertainment options. If you're up for a drive, visit Patio Design LifeStyle Center for a unique shopping experience, or explore La Recova Artisan Walk for charming local crafts and souvenirs. **Recreation** Ramon Tahuichi Aguilera Stadium offers a vibrant atmosphere for sports enthusiasts, where you can engage in various recreational activities. Experience the thrill of local sporting events while soaking up the energetic ambience of this iconic venue, which showcases the passion of Santa Cruz's sporting culture. **Adventure** The Amboró National Park offers breathtaking landscapes and diverse wildlife, perfect for hiking and birdwatching. Experience thrilling zip-lining at Parque Lomas de Arena, where you can glide over stunning sand dunes. For a unique adventure, explore the nearby Chiquitania region, known for its beautiful Jesuit missions and captivating nature. **Nightlife** The nightlife in Santa Cruz offers a vibrant mix of entertainment. Start your evening at Cine Center, a cinema perfect for family outings or a romantic film. For a lively atmosphere, explore nearby bars and clubs that pulse with energy and local culture. ### Booking tips and Expedia advantages for Santa Cruz For a budget-friendly visit to Santa Cruz, consider travelling in June, August, or November when prices are lower. Saturday is the cheapest day to book accommodation, while Tuesday tends to be the priciest. Use Expedia to compare hotel rates and find eco-friendly options. By bundling your hotel, flights, and activities, you can save significantly. Take advantage of free activities in the city and opt for public transport to keep your travel costs down. This approach will help you enjoy Santa Cruz without breaking the bank. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santa Cruz are June, August and November, where the prices are slightly lower. This is in comparison to March to April and September, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday. - **Find cheap hotels on Expedia:** Expedia's search tool enables you to specify your budget, preferred location, and additional criteria. You can arrange your results to display prices from lowest to highest, allowing you to identify the most affordable hotels first. Additionally, you have the option to refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels available for booking. - **Consider bundling your trip:** You may find that by combining your Santa Cruz hotel reservation with your flights and activities through an Expedia package, you can enjoy considerable savings. ### Find the best attractions in Santa Cruz Santa Cruz, Bolivia, offers a delightful blend of outdoor adventures and cultural experiences, making it perfect for family vacations. Explore national parks, stunning cathedrals, and iconic landmarks that showcase the region's rich heritage. With a variety of attractions catering to those seeking adventure and culture, Santa Cruz is an excellent choice for travellers looking to immerse themselves in its vibrant atmosphere and natural beauty. - **[Amboró National Park: ](https://www.expedia.co.uk/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels)** Explore the breathtaking landscapes of Amboró National Park, where adventure awaits at every turn. With its rich biodiversity and stunning scenery, this haven is perfect for hiking, bird-watching, and immersing yourself in nature’s beauty. - **[YPFB Plant: ](https://www.expedia.co.uk/YPFB-Plant-Hotels.0-l553248621532375435-0.Travel-Guide-Filter-Hotels)** Visit the YPFB Plant, a significant landmark in Santa Cruz, where you can learn about Bolivia's energy production and the role it plays in the economy. An insightful experience for those interested in industry and innovation. - **Plaza 24 de Septiembre:** Experience the vibrant atmosphere of Plaza 24 de Septiembre, the cultural heart of Santa Cruz. Surrounded by charming architecture, it’s a perfect spot for people-watching and soaking up local culture. ### Best time to go to Santa Cruz The best time to visit Santa Cruz is dependant on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 78.3°F (25.700000000000003°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | February | 77.0°F (25.0°C) | Light Rain | Mostly Cloudy | Slightly High | Average | | March | 76.5°F (24.700000000000003°C) | Light Rain | Mostly Sunny | Average | Slightly High | | April | 74.5°F (23.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 70.2°F (21.200000000000003°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | June | 67.8°F (19.9°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | July | 68.5°F (20.3°C) | No Rain (Dry) | Mostly Sunny | Average | Average | | August | 72.9°F (22.700000000000003°C) | No Rain (Dry) | Sunny | Slightly High | Slightly Low | | September | 77.9°F (25.5°C) | Light Rain | Sunny | Slightly High | Slightly High | | October | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Average | Average | | November | 79.3°F (26.3°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Slightly Low | Average | ### The nearest major airports for your trip to Santa Cruz Flying into Santa Cruz, Bolivia, is convenient with the main airport being Viru Viru International Airport ([VVI](https://www.expedia.co.uk/Viru-Viru-Intl-Airport-Hotels.0-aVVI-0.Travel-Guide-Filter-Hotels)), situated 6.2km from the city. Excellent hotel options nearby include the 5-star Marriott Santa Cruz de la Sierra and Radisson Hotel, both 5.6km away, and the 4.5-star Swissôtel, just 5.0km from the airport. These hotels offer various transportation services, including airport shuttles. Alternatively, for those considering Sucre, Juana Azurduy de Padilla International Airport (SRE) is located 100.7km away, with hotels like [Parador Santa Maria La Real](https://www.expedia.co.uk/Sucre-Hotels-Parador-Santa-Maria-La-Real.h1559055.Hotel-Information) and [Hotel de Su Merced](https://www.expedia.co.uk/Sucre-Hotels-Hotel-De-Su-Merced.h3498186.Hotel-Information) providing shuttle services for guests. ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Santa Cruz - [Santa Cruz Hotels ](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) - [Samaipata Hotels ](https://expedia.co.uk/Samaipata-Hotels.d6200976.Travel-Guide-Hotels) - [Warnes Hotels ](https://expedia.co.uk/Warnes-Hotels.d6352296.Travel-Guide-Hotels) - [Montero Hotels ](https://expedia.co.uk/Montero-Hotels.d553248635975872931.Travel-Guide-Hotels) - [San Jose de Chiquitos Hotels ](https://expedia.co.uk/San-Jose-De-Chiquitos-Hotels.d6344854.Travel-Guide-Hotels) - [Cuevas Hotels ](https://expedia.co.uk/Cuevas-Hotels.d6350209.Travel-Guide-Hotels) - [Puerto Quijarro Hotels ](https://expedia.co.uk/Puerto-Quijarro-Hotels.d3000389058.Travel-Guide-Hotels) - [Roboré Hotels ](https://expedia.co.uk/Robore-Hotels.d3000408084.Travel-Guide-Hotels) - [La Guardia Hotels ](https://expedia.co.uk/La-Guardia-Hotels.d6347124.Travel-Guide-Hotels) - [La Higuera Hotels ](https://expedia.co.uk/La-Higuera-Hotels.d830373381713960960.Travel-Guide-Hotels) - [Buena Vista Hotels ](https://expedia.co.uk/Buena-Vista-Hotels.d3000445595.Travel-Guide-Hotels) - [Concepcion Hotels ](https://expedia.co.uk/Concepcion-Hotels.d6353167.Travel-Guide-Hotels) - [Camiri Hotels ](https://expedia.co.uk/Camiri-Hotels.d770.Travel-Guide-Hotels) - [San Javier Hotels ](https://expedia.co.uk/San-Javier-Hotels.d6350629.Travel-Guide-Hotels) - [Vallegrande Hotels ](https://expedia.co.uk/Vallegrande-Hotels.d6350207.Travel-Guide-Hotels) - [Puerto Suarez Hotels ](https://expedia.co.uk/Puerto-Suarez-Hotels.d3000470804.Travel-Guide-Hotels) - [Municipio Puerto Quijarro Hotels ](https://expedia.co.uk/Municipio-Puerto-Quijarro-Hotels.d553248634664650782.Travel-Guide-Hotels) - [Estancia Aguas Calientes Hotels ](https://expedia.co.uk/Estancia-Aguas-Calientes-Hotels.d631238765802795008.Travel-Guide-Hotels) - [Portachuelo Hotels ](https://expedia.co.uk/Portachuelo-Hotels.d553248635975857300.Travel-Guide-Hotels) - [Santa Rosa De La Mina Hotels ](https://expedia.co.uk/Santa-Rosa-De-La-Mina-Hotels.d3000007078.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Amboró National Park ](https://expedia.co.uk/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels) ### Hotels near Santa Cruz Airports - [Viru Viru Intl. Airport Hotels ](https://expedia.co.uk/Viru-Viru-Intl-Airport-Hotels.0-aVVI-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Ibis Santa Cruz DE LA Sierra ](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) - [Camino Real Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) - [Marriott Santa Cruz de la Sierra Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) - [Hotel Las Américas ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Las-Americas.h112993678.Hotel-Information) - [Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) - [Sun Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) - [HOTEL OSHO ](https://expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) - [Hotel Cortez ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) [See a list of all hotels in Santa Cruz](https://expedia.co.uk/All-Santa-Cruz-Hotels.d6297178.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Hotel-Destinations) - [University of Bath hotels](https://expedia.co.uk/University-Of-Bath-Hotels.0-l6079389-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Hotels in Rio de Janeiro State](https://expedia.co.uk/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Amber Springs Hotel & Health Spa](https://expedia.co.uk/Gorey-Hotels-Amber-Springs-Hotel-Health-Spa.h6603206.Hotel-Information) - [Formby Hall Golf Resort & Spa](https://expedia.co.uk/Liverpool-Hotels-Formby-Hall-Golf-Resort-Spa.h1833053.Hotel-Information) - [Notting Hill Cheap Hotels](https://expedia.co.uk/Notting-Hill-London-Hotels-Budget-Hotels.0-n601720-0-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Secrets St. Lucia Resort & Spa All Inclusive Adults Only](https://expedia.co.uk/Gros-Islet-Hotels-St-Jamess-Club-Morgan-Bay-All-Inclusive.h16440.Hotel-Information) - [Hotels in Switzerland](https://expedia.co.uk/Destinations-In-Switzerland.d174.Hotel-Destinations) Flights - [Cheap Flights to Tierra del Fuego Province](https://expedia.co.uk/Destinations-In-Tierra-Del-Fuego-Province.d6208785.Flight-Destinations) - [Cheap Flights to Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Flights from Liverpool to Galway](https://expedia.co.uk/lp/flights/lpl/gwy/liverpool-to-galway) - [Iberia London (LHR) to Madrid (MAD) flights](https://expedia.co.uk/lp/flight-routes/iberia-from-heathrow-to-adolfo-suarez-madrid-barajas/ib/lhr/mad) - [Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights) - [Cheap Flights to Cusco Region](https://expedia.co.uk/Destinations-In-Cusco-Region.d6235224.Flight-Destinations) Activities - [Things to do in Costa de Antigua](https://expedia.co.uk/Things-To-Do-In-Costa-De-Antigua.d6213265.Travel-Guide-Activities) Packages - [Florida Holidays](https://expedia.co.uk/Florida.d6278083.Holidays-City-Breaks) - [Bahia State Holidays](https://expedia.co.uk/Bahia-State.d6052623.Holidays-City-Breaks) - [Santa Catarina Holidays](https://expedia.co.uk/Santa-Catarina.d6052646.Holidays-City-Breaks) - [Alagoas Holidays](https://expedia.co.uk/Alagoas.d6052620.Holidays-City-Breaks) - [Galápagos Holidays](https://expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) Holiday Rentals - [Holiday Rentals Bracknell](https://expedia.co.uk/Bracknell-Holiday-Rentals.d4580.Travel-Guide-HolidayRentals) - [Holiday Rentals Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Holiday-Rental-Destinations) General - [Visit Addu Atoll](https://expedia.co.uk/Addu-Atoll.dx6125023) - [Visit Bradford](https://expedia.co.uk/Bradford.dx4981) - [Visit Jujuy Province](https://expedia.co.uk/Jujuy-Province.dx6232492) - [Visit Paraná](https://expedia.co.uk/Parana.dx6052638) - [Visit Mato Grosso do Sul](https://expedia.co.uk/Mato-Grosso-Do-Sul.dx6052631) - [Visit Magallanes y Antartica Chilena](https://expedia.co.uk/Magallanes-Y-Antartica-Chilena.dx6236290) - [Visit Santa Catarina](https://expedia.co.uk/Santa-Catarina.dx6052646) - [Visit Rio Grande do Sul](https://expedia.co.uk/Rio-Grande-Do-Sul.dx6052643) ## Frequently asked questions ### How much do hotels in Santa Cruz cost? ### When is the best time to go to Santa Cruz? ### Are there any luxury hotels in Santa Cruz? ### What are the top all-inclusive hotels in Santa Cruz? ### How can I find cheap hotels in Santa Cruz? ### What are the best hotels in Santa Cruz for families? ### Why should I book my Santa Cruz hotel with Expedia? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app