Title: Top Hotels in Santa Cruz - Compare Santa Cruz Hotels | Expedia.co.uk [Holiday Rentals in Santa Cruz](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations)[Santa Cruz Flights](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Santa Cruz Car Hire](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Car-Hire-Destinations)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6297178.Holidays-City-Breaks) ![Lake Titicaca featuring general coastal views and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240645-Lake-Titicaca.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best Santa Cruz Hotels ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Cruz Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2025-10-03&d1=2025-10-03&endDate=2025-10-05&d2=2025-10-05&amenities=SPA_ON_SITE) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2025-10-03&d1=2025-10-03&endDate=2025-10-05&d2=2025-10-05&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2025-10-03&d1=2025-10-03&endDate=2025-10-05&d2=2025-10-05&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2025-10-03&d1=2025-10-03&endDate=2025-10-05&d2=2025-10-05&amenities=HOT_TUB) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2025-10-03&d1=2025-10-03&endDate=2025-10-05&d2=2025-10-05&lodging=APARTMENT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2025-10-03&d1=2025-10-03&endDate=2025-10-05&d2=2025-10-05&amenities=PETS) ## Santa Cruz Accommodation: Most Popular Cities to Stay ![San Lorenzo Cathedral showing a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/115000/115563-Santa-Cruz.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) ![](https://mediaim.expedia.com/destination/2/06496d3cec9b6cad4a738ddeb6156d1c.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Samaipata [](https://expedia.co.uk/Samaipata-Hotels.d6200976.Travel-Guide-Hotels) ![](https://mediaim.expedia.com/destination/2/101c2fd6556e96d089a24b3e99f984cc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Javier [](https://expedia.co.uk/San-Javier-Hotels.d6350629.Travel-Guide-Hotels) ## Check prices for these dates Tonight [19 Sept - 20 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-09-19&endDate=2025-09-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-09-20&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-09-19&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6297178&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Santa Cruz ## Our top choices for Santa Cruz hotels ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/4f7a4f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/e8e161c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/f930f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Santa Cruz de la Sierra Hotel Santa Cruz 9.0/10 Wonderful (195) "Great hotel, food and location albeit a little expensive " £76 11 Oct - 12 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 Double Bed | Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/d249effb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/c96e3d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/9bf66d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel Santa Cruz 9.0/10 Wonderful (330) "Los Tajibos is perhaps the best place to stay in Santa Cruz." £97 12 Oct - 13 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/0ffe84ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, swim-up bar, poolside bar](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/96ef3d87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camino Real Hotel Santa Cruz 8.8/10 Excellent (400) "Great Hotel, had a great time ." £103 12 Oct - 13 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/640c92ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/ecd38ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/c31e2727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/3c769140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ibis Santa Cruz DE LA Sierra Santa Cruz 9.6/10 Exceptional (55) "Basic hotel with very friendly staff. The staff is superb Very nice neighborhood!!!nice shopping and great restaurants !" £27 29 Sept - 30 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/7bebfbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/e77454e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/34d33eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia Santa Cruz 9.2/10 Wonderful (249) "Nice hotel " £76 4 Oct - 5 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/6bafe83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/b24e36f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/a6a85fc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cortez Santa Cruz 9.0/10 Wonderful (112) "The staff and property are second to none! " £88 30 Sept - 1 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room, 1 King Bed, Pool View | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/07bd498f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/a62fe987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/e63a6005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sun Hotel Santa Cruz 8.4/10 Very good (318) "Todo excelente " £71 23 Sept - 24 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/b0eabde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment, Terrace | Private kitchen | Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/cb07702a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, Terrace (Plus) | 1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/bb64c9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz Santa Cruz 8.6/10 Excellent (92) "Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/3a211a94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor wedding](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/03ce2f25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/53f3f30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed | 1 bedroom, premium bedding, down duvets, Select Comfort beds](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/8c1d4245.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Santa Cruz De La Sierra Santa Cruz 9.2/10 Wonderful (97) "Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. " £77 12 Oct - 13 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/26a3b61a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/7b4c5ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/a92c6796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lido Hotel Santa Cruz 9.0/10 Wonderful (27) "Staff is amazing, It is a friendly environment. Our flight was delayed the previous night that we couldn't make it to the hotel and they honored our request. " £33 8 Oct - 9 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/a3164128_edited_3199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Minibar, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/d0346687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/a3d55de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/20d0c7ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Delfines Collection Hotel By Mercure Santa Cruz 9.0/10 Wonderful (61) "Clean comfortable rooms " £34 4 Oct - 5 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) ![Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/6f72135a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 2 Bedrooms, Non Smoking | Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/8d7975b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/a3100f49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Santa Cruz Santa Cruz 9.2/10 Wonderful (132) "Nice stay with good service " £64 20 Sept - 21 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/6c281819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/0132556f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/4810f028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel LP Santa Cruz Centro Santa Cruz 8.0/10 Very good (280) "Clean, friendly staff" [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/47e3b432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Room, 3 Single Beds | Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/734a9fe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/5b173b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/1afa63fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel LP Equipetrol Santa Cruz 8.2/10 Very good (199) "Nice place to stay" [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Equipetrol.h10209582.Hotel-Information) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/12ef5e8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Apartment, 1 King Bed with Sofa bed, Terrace | 2 bedrooms, premium bedding, down duvets, Tempur-Pedic beds](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/72a81d70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/f316b83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/cbf735a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol Santa Cruz 9.0/10 Wonderful (74) "Good price, great hotel!" [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/791dee64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/27fe59c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/18aa722e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/2426ba60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swissôtel Santa Cruz De La Sierra Santa Cruz 9.2/10 Wonderful (79) "Beautiful hotel" £87 4 Oct - 5 Oct [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/6fe72ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/eca5a1cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/3e3efa0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chairú Eco Hotel Santa Cruz 9.4/10 Exceptional (39) "Nice and clean hotel " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Comfort Room | Private kitchen | Mini-fridge, dining tables](https://images.trvl-media.com/lodging/28000000/27670000/27664900/27664803/b6463a13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 1 King Bed | Bathroom | Eco-friendly toiletries, towels, soap, shampoo](https://images.trvl-media.com/lodging/28000000/27670000/27664900/27664803/f488efa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 1 King Bed | Room amenity](https://images.trvl-media.com/lodging/28000000/27670000/27664900/27664803/2d5ae648.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![34-inch LCD TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/28000000/27670000/27664900/27664803/326b4abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel G Santa Cruz 7.8/10 Good (104) "Excelente Hotel " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-G.h27664803.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/91000000/90310000/90308900/90308824/2b333f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handrails in hallways](https://images.trvl-media.com/lodging/91000000/90310000/90308900/90308824/84748c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/91000000/90310000/90308900/90308824/cab82ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90310000/90308900/90308824/5f73cd06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### residencial francia - Hostel Santa Cruz 7.0/10 Good (4) "it was average not bad" £11 20 Sept - 21 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Residencial-Francia.h90308824.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/34ce662d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/f57583c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/a17b45cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/6fe3cece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buganvillas Hotel Suites & Spa Santa Cruz 7.4/10 Good (92) "Gammelt og veldig slitt og skittent. Det var et fint hotell for 20 år siden. Men ikke vedlikeholdt. " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Buganvillas-Hotel-Suites-Spa.h1156088.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04®ionId=6297178&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Santa Cruz Showing deals for:26 Sept - 28 Sept ![House | Pool | Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/16000000/15040000/15030900/15030862/cb1eeefb.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Casa Vida Santa Cruz 9.0/10Wonderful (2 reviews) 10% off £139 for 2 nights, 1 home £70 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=15030862&adults=2) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/a7124411.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Alfonsina Hotel Boutique by Inboccaluppo Santa Cruz 9.4/10Exceptional (38 reviews) 10% off £198 for 2 nights, 1 room £99 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=10202755&adults=2) ![Exterior](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/82a3e31e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### HOTEL OSHO Santa Cruz 9.0/10Wonderful (25 reviews) 19% off £78 for 2 nights, 1 room £39 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=75254801&adults=2) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/791dee64.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Swissôtel Santa Cruz De La Sierra Santa Cruz 9.2/10Wonderful (79 reviews) Member Price available £226 for 2 nights, 1 room £113 per night [Sign in for Member Price](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-09-26%26endDate%3D2025-09-28%26selected%3D60335614%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=60335614&adults=2) ![Living area](https://images.trvl-media.com/lodging/119000000/118180000/118176600/118176582/322f09bb.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Posada Express Fast Check Santa Cruz 10/10Exceptional (1 review) Member Price available £80 for 2 nights, 1 room £40 per night [Sign in for Member Price](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-09-26%26endDate%3D2025-09-28%26selected%3D118176582%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=118176582&adults=2) ![Front of property](https://images.trvl-media.com/lodging/16000000/15250000/15240400/15240320/f9ae8716.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Continental Park Santa Cruz 8.6/10Excellent (24 reviews) 12% off £111 for 2 nights, 1 room £56 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=15240320&adults=2) ![Front of property – evening/night](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/47e3b432.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Hotel LP Equipetrol Santa Cruz 8.2/10Very good (199 reviews) 30% off £94 for 2 nights, 1 room £47 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=10209582&adults=2) ![Reception](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Cortez Santa Cruz 9.0/10Wonderful (112 reviews) Member Price available £215 for 2 nights, 1 room £107 per night [Sign in for Member Price](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-09-26%26endDate%3D2025-09-28%26selected%3D13455822%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=13455822&adults=2) ![Standard Suite, 2 Single Beds | 1 bedroom, hypo-allergenic bedding, down duvets, desk](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/2b6207d2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Equipetrol Suites Apart Hotel Santa Cruz 8.4/10Very good (7 reviews) 10% off £63 for 2 nights, 1 room £32 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=90599395&adults=2) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Sun Hotel Santa Cruz 8.4/10Very good (318 reviews) 19% off £143 for 2 nights, 1 room £72 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=12836211&adults=2) ![Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/18000000/17520000/17512600/17512569/9825bb16.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Cosmopolitano Hotel Boutique Santa Cruz 9.2/10Wonderful (121 reviews) 23% off £180 for 2 nights, 1 room £90 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=17512569&adults=2) ![Reception](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lido Hotel Santa Cruz 9.0/10Wonderful (27 reviews) 12% off £62 for 2 nights, 1 room £31 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=98237549&adults=2) ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Chairú Eco Hotel Santa Cruz 9.4/10Exceptional (39 reviews) 36% off £85 for 2 nights, 1 room £42 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=82389693&adults=2) ![Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Hotel LP Santa Cruz Centro Santa Cruz 8.0/10Very good (280 reviews) 30% off £65 for 2 nights, 1 room £32 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=2761435&adults=2) ![Sports facility](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/640c92ef.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Ibis Santa Cruz DE LA Sierra Santa Cruz 9.6/10Exceptional (55 reviews) 23% off £125 for 2 nights, 1 room £63 per night [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=87138613&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Hotel-Destinations) ## Top Santa Cruz Hotel Reviews ![Apart Hotel Premium Suites Santa Cruz](//images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260_y.jpg) ### Apart Hotel Premium Suites Santa Cruz 10/10 Excellent "Es buena locación , limpio , muy amables" [](https://expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Marriott Santa Cruz de la Sierra Hotel](//images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 10/10 Excellent "Nice" [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Los Tajibos is perhaps the best place to stay in Santa Cruz." [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Sun Hotel](//images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "Friendly and staff very cooperative." [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Camino Real Hotel](//images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Very comfortable, great location. My favorite in Santa Cruz. Big enough / small enough" [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Chairú Eco Hotel](//images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Like clean close to the city and malls are " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](//images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/640c92ef_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "The " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Lido Hotel](//images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f_y.jpg) ### Lido Hotel 10/10 Excellent "Clean, with AC and both hot and cold water. " [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ![Hotel Cortez](//images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0_y.jpg) ### Hotel Cortez 10/10 Excellent "The staff and property are second to none! " [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) ## Guide to exploring Santa Cruz ### Top reasons to visit Santa Cruz - **Outdoor Adventures:** Santa Cruz is perfect for outdoor enthusiasts, offering scenic hiking trails and national parks for exploration. - **Cultural Experiences:** Immerse yourself in the rich heritage through stunning cathedrals and iconic landmarks that reflect the local culture. - **Vibrant City Life:** The bustling city centre boasts lively nightlife and stunning views, ideal for a vibrant urban experience. - **Diverse Accommodation:** Enjoy a range of lodging options, from charming bed and breakfasts to well-rated hotels catering to all needs. - **Relaxation Opportunities:** Unwind at resorts and enjoy leisure activities, making it a great destination for families and relaxation seekers. ### Find great hotels in Santa Cruz Santa Cruz, Bolivia, offers a diverse selection of accommodation options, from charming bed and breakfasts to well-rated hotels. Whether you're seeking a family-friendly retreat, a pet-friendly getaway, or a business-themed stay, the city has something to cater to every traveler's needs. Explore the best hotels in Santa Cruz to ensure a comfortable and enjoyable experience while immersing yourself in the vibrant culture of this lively destination. - **[Hotel G:](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-G.h27664803.Hotel-Information)** Hotel G is a charming 3.5-star hotel that offers a unique pet-friendly experience in the heart of Santa Cruz. This property caters to travellers who wish to enjoy their holiday alongside their furry companions, as it permits dogs and cats onsite. Guests appreciate the welcoming atmosphere and the dedicated amenities for pets, ensuring a comfortable stay for both humans and their four-legged friends. With its cosy rooms and friendly service, Hotel G is an excellent choice for those seeking a relaxed getaway. - **Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel:** Positioned in the vibrant city centre, Los Tajibos is a sophisticated 3.5-star hotel that perfectly blends business functionality with family-friendly comfort. Ideal for corporate travellers, it boasts comprehensive business amenities, including a conference centre and accessible business centre. Families will love the thoughtful features for children, such as a dedicated pool area. The combination of modern design and attentive service makes Los Tajibos a great choice for both work and leisure. - **[Marriott Santa Cruz de la Sierra Hotel:](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information)** The luxurious 5-star Marriott Santa Cruz de la Sierra Hotel is an upscale haven for travellers seeking elegance and comfort. This property is well-equipped for business and family stays, offering extensive meeting facilities and an accessible business centre. The hotel also caters to families with amenities like complimentary cribs, making it a convenient choice for those travelling with young children. With its high-end services and prime location, the Marriott promises an indulgent stay in Santa Cruz. ### Where to stay in Santa Cruz Santa Cruz, Bolivia, offers a vibrant blend of outdoor adventures and cultural experiences in a tropical setting. Explore the bustling city centre, where stunning views and lively nightlife await. Whether you're seeking a secluded getaway or a budget-friendly family vacation, Santa Cruz provides the perfect backdrop for unforgettable excursions. Discover the warmth of the local atmosphere and immerse yourself in the rich culture that makes this destination truly unique. - **[Santa Cruz:](https://www.expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)** As the largest city in Bolivia, Santa Cruz is a vibrant hub of commerce and culture. Nestled in the eastern part of the country, it boasts a tropical climate that attracts visitors year-round. The city is ideal for those seeking a mix of urban experiences, with its shopping centres and bustling markets. Highlights include the picturesque piazza square, the lush botanical garden, and the impressive stadium. Whether you're enjoying a family outing or exploring the city's rich offerings, Santa Cruz promises an engaging experience. - **[Samaipata:](https://www.expedia.co.uk/Samaipata-Hotels.d6200976.Travel-Guide-Hotels)** A short drive from Santa Cruz, Samaipata is a charming town known for its stunning natural landscapes and outdoor adventures. Nestled in the foothills of the Andes, it offers breathtaking scenery and a plethora of hiking trails for the adventurous spirit. The area is steeped in history, with notable archaeological and historic sites that reflect its rich past. Visitors can enjoy local markets and relax in quaint resorts, making it a perfect getaway for those seeking a blend of adventure and tranquillity. - **[Warnes:](https://www.expedia.co.uk/Warnes-Hotels.d6352296.Travel-Guide-Hotels)** Located conveniently close to Santa Cruz, Warnes is a bustling city that caters to families and business travellers alike. This vibrant area features modern shopping centres and malls, making it a great destination for retail therapy. Notable local attractions include beautiful places of worship and serene botanical gardens, providing a peaceful escape amidst the urban setting. With a welcoming atmosphere and a range of amenities, Warnes is a delightful stop for anyone exploring the region. ### Things to do in Santa Cruz Santa Cruz, Bolivia, is an excellent destination for outdoor enthusiasts and families seeking cultural experiences. Visitors can enjoy a variety of activities, including relaxation at resorts, exploring scenic hiking trails, and catching a film at local cinemas. This vibrant city offers a delightful blend of adventure and leisure, making it an ideal spot for a memorable holiday. **Shopping** In Santa Cruz, you can shop at Ventura Mall, which offers a lively atmosphere with various shops and entertainment options. If you're up for a drive, visit Patio Design LifeStyle Center for a unique shopping experience, or explore La Recova Artisan Walk for charming local crafts and souvenirs. **Recreation** Ramon Tahuichi Aguilera Stadium offers a vibrant atmosphere for sports enthusiasts, where you can engage in various recreational activities. Experience the thrill of local sporting events while soaking up the energetic ambience of this iconic venue, which showcases the passion of Santa Cruz's sporting culture. **Adventure** The Amboró National Park offers breathtaking landscapes and diverse wildlife, perfect for hiking and birdwatching. Experience thrilling zip-lining at Parque Lomas de Arena, where you can glide over stunning sand dunes. For a unique adventure, explore the nearby Chiquitania region, known for its beautiful Jesuit missions and captivating nature. **Nightlife** The nightlife in Santa Cruz offers a vibrant mix of entertainment. Start your evening at Cine Center, a cinema perfect for family outings or a romantic film. For a lively atmosphere, explore nearby bars and clubs that pulse with energy and local culture. ### Booking tips and Expedia advantages for Santa Cruz For a budget-friendly visit to Santa Cruz, consider travelling in June, August, or November when prices are lower. Saturday is the cheapest day to book accommodation, while Tuesday tends to be the priciest. Use Expedia to compare hotel rates and find eco-friendly options. By bundling your hotel, flights, and activities, you can save significantly. Take advantage of free activities in the city and opt for public transport to keep your travel costs down. This approach will help you enjoy Santa Cruz without breaking the bank. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santa Cruz are June, August and November, where the prices are slightly lower. This is in comparison to March to April and September, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday. - **Find cheap hotels on Expedia:** Expedia's search tool enables you to specify your budget, preferred location, and additional criteria. You can arrange your results to display prices from lowest to highest, allowing you to identify the most affordable hotels first. Additionally, you have the option to refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels available for booking. - **Consider bundling your trip:** You may find that by combining your Santa Cruz hotel reservation with your flights and activities through an Expedia package, you can enjoy considerable savings. ### Find the best attractions in Santa Cruz Santa Cruz, Bolivia, offers a delightful blend of outdoor adventures and cultural experiences, making it perfect for family vacations. Explore national parks, stunning cathedrals, and iconic landmarks that showcase the region's rich heritage. With a variety of attractions catering to those seeking adventure and culture, Santa Cruz is an excellent choice for travellers looking to immerse themselves in its vibrant atmosphere and natural beauty. - **[Amboró National Park:](https://www.expedia.co.uk/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels)** Explore the breathtaking landscapes of Amboró National Park, where adventure awaits at every turn. With its rich biodiversity and stunning scenery, this haven is perfect for hiking, bird-watching, and immersing yourself in nature’s beauty. - **[YPFB Plant:](https://www.expedia.co.uk/YPFB-Plant-Hotels.0-l553248621532375435-0.Travel-Guide-Filter-Hotels)** Visit the YPFB Plant, a significant landmark in Santa Cruz, where you can learn about Bolivia's energy production and the role it plays in the economy. An insightful experience for those interested in industry and innovation. - **Plaza 24 de Septiembre:** Experience the vibrant atmosphere of Plaza 24 de Septiembre, the cultural heart of Santa Cruz. Surrounded by charming architecture, it’s a perfect spot for people-watching and soaking up local culture. ### Best time to go to Santa Cruz The best time to visit Santa Cruz is dependant on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 78.3°F (25.700000000000003°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | February | 77.0°F (25.0°C) | Light Rain | Mostly Cloudy | Slightly High | Average | | March | 76.5°F (24.700000000000003°C) | Light Rain | Mostly Sunny | Average | Slightly High | | April | 74.5°F (23.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 70.2°F (21.200000000000003°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | June | 67.8°F (19.9°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | July | 68.5°F (20.3°C) | No Rain (Dry) | Mostly Sunny | Average | Average | | August | 72.9°F (22.700000000000003°C) | No Rain (Dry) | Sunny | Slightly High | Slightly Low | | September | 77.9°F (25.5°C) | Light Rain | Sunny | Slightly High | Slightly High | | October | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Average | Average | | November | 79.3°F (26.3°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Slightly Low | Average | ### The nearest major airports for your trip to Santa Cruz Flying into Santa Cruz, Bolivia, is convenient with the main airport being Viru Viru International Airport ([VVI](https://www.expedia.co.uk/Viru-Viru-Intl-Airport-Hotels.0-aVVI-0.Travel-Guide-Filter-Hotels)), situated 6.2km from the city. Excellent hotel options nearby include the 5-star Marriott Santa Cruz de la Sierra and Radisson Hotel, both 5.6km away, and the 4.5-star Swissôtel, just 5.0km from the airport. These hotels offer various transportation services, including airport shuttles. Alternatively, for those considering Sucre, Juana Azurduy de Padilla International Airport (SRE) is located 100.7km away, with hotels like [Parador Santa Maria La Real](https://www.expedia.co.uk/Sucre-Hotels-Parador-Santa-Maria-La-Real.h1559055.Hotel-Information) and [Hotel de Su Merced](https://www.expedia.co.uk/Sucre-Hotels-Hotel-De-Su-Merced.h3498186.Hotel-Information) providing shuttle services for guests. ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Santa Cruz - [Santa Cruz Hotels](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) - [Samaipata Hotels](https://expedia.co.uk/Samaipata-Hotels.d6200976.Travel-Guide-Hotels) - [Montero Hotels](https://expedia.co.uk/Montero-Hotels.d553248635975872931.Travel-Guide-Hotels) - [San Jose de Chiquitos Hotels](https://expedia.co.uk/San-Jose-De-Chiquitos-Hotels.d6344854.Travel-Guide-Hotels) - [Warnes Hotels](https://expedia.co.uk/Warnes-Hotels.d6352296.Travel-Guide-Hotels) - [Camiri Hotels](https://expedia.co.uk/Camiri-Hotels.d770.Travel-Guide-Hotels) - [La Guardia Hotels](https://expedia.co.uk/La-Guardia-Hotels.d6347124.Travel-Guide-Hotels) - [Puerto Quijarro Hotels](https://expedia.co.uk/Puerto-Quijarro-Hotels.d3000389058.Travel-Guide-Hotels) - [Concepcion Hotels](https://expedia.co.uk/Concepcion-Hotels.d6353167.Travel-Guide-Hotels) - [Cuevas Hotels](https://expedia.co.uk/Cuevas-Hotels.d6350209.Travel-Guide-Hotels) - [Roboré Hotels](https://expedia.co.uk/Robore-Hotels.d3000408084.Travel-Guide-Hotels) - [Municipio Puerto Quijarro Hotels](https://expedia.co.uk/Municipio-Puerto-Quijarro-Hotels.d553248634664650782.Travel-Guide-Hotels) - [San Ignacio de Velasco Hotels](https://expedia.co.uk/San-Ignacio-De-Velasco-Hotels.d6161202.Travel-Guide-Hotels) - [Estancia Aguas Calientes Hotels](https://expedia.co.uk/Estancia-Aguas-Calientes-Hotels.d631238765802795008.Travel-Guide-Hotels) - [Comarapa Hotels](https://expedia.co.uk/Comarapa-Hotels.d3000422622.Travel-Guide-Hotels) - [San Javier Hotels](https://expedia.co.uk/San-Javier-Hotels.d6350629.Travel-Guide-Hotels) - [Buena Vista Hotels](https://expedia.co.uk/Buena-Vista-Hotels.d3000445595.Travel-Guide-Hotels) - [La Higuera Hotels](https://expedia.co.uk/La-Higuera-Hotels.d830373381713960960.Travel-Guide-Hotels) - [Portachuelo Hotels](https://expedia.co.uk/Portachuelo-Hotels.d553248635975857300.Travel-Guide-Hotels) - [Puerto Suarez Hotels](https://expedia.co.uk/Puerto-Suarez-Hotels.d3000470804.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Amboró National Park](https://expedia.co.uk/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels) ### Hotels near Santa Cruz Airports - [Viru Viru Intl. Airport Hotels](https://expedia.co.uk/Viru-Viru-Intl-Airport-Hotels.0-aVVI-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Ibis Santa Cruz DE LA Sierra](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) - [Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) - [Marriott Santa Cruz de la Sierra Hotel](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) - [Camino Real Hotel](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) - [Sun Hotel](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) - [Apart Hotel Premium Suites Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) [See a list of all hotels in Santa Cruz](https://expedia.co.uk/All-Santa-Cruz-Hotels.d6297178.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Hotel-Destinations) - [University of Bath hotels](https://expedia.co.uk/University-Of-Bath-Hotels.0-l6079389-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Hotels in Rio de Janeiro State](https://expedia.co.uk/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Amber Springs Hotel & Health Spa](https://expedia.co.uk/Gorey-Hotels-Amber-Springs-Hotel-Health-Spa.h6603206.Hotel-Information) - [Formby Hall Golf Resort & Spa](https://expedia.co.uk/Liverpool-Hotels-Formby-Hall-Golf-Resort-Spa.h1833053.Hotel-Information) - [Notting Hill Cheap Hotels](https://expedia.co.uk/Notting-Hill-London-Hotels-Budget-Hotels.0-n601720-0-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Secrets St. Lucia Resort & Spa All Inclusive Adults Only](https://expedia.co.uk/Gros-Islet-Hotels-St-Jamess-Club-Morgan-Bay-All-Inclusive.h16440.Hotel-Information) - [Hotels in Switzerland](https://expedia.co.uk/Destinations-In-Switzerland.d174.Hotel-Destinations) Flights - [Cheap Flights to Tierra del Fuego Province](https://expedia.co.uk/Destinations-In-Tierra-Del-Fuego-Province.d6208785.Flight-Destinations) - [Cheap Flights to Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Flights from Liverpool to Galway](https://expedia.co.uk/lp/flights/lpl/gwy/liverpool-to-galway) - [Iberia London (LHR) to Madrid (MAD) flights](https://expedia.co.uk/lp/flight-routes/iberia-from-heathrow-to-adolfo-suarez-madrid-barajas/ib/lhr/mad) - [Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights) - [Cheap Flights to Cusco Region](https://expedia.co.uk/Destinations-In-Cusco-Region.d6235224.Flight-Destinations) Activities - [Things to do in Costa de Antigua](https://expedia.co.uk/Things-To-Do-In-Costa-De-Antigua.d6213265.Travel-Guide-Activities) Packages - [Florida Holidays](https://expedia.co.uk/Florida.d6278083.Holidays-City-Breaks) - [Bahia State Holidays](https://expedia.co.uk/Bahia-State.d6052623.Holidays-City-Breaks) - [Santa Catarina Holidays](https://expedia.co.uk/Santa-Catarina.d6052646.Holidays-City-Breaks) - [Alagoas Holidays](https://expedia.co.uk/Alagoas.d6052620.Holidays-City-Breaks) - [Galápagos Holidays](https://expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) Holiday Rentals - [Holiday Rentals Bracknell](https://expedia.co.uk/Bracknell-Holiday-Rentals.d4580.Travel-Guide-HolidayRentals) - [Holiday Rentals Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Holiday-Rental-Destinations) General - [Visit Addu Atoll](https://expedia.co.uk/Addu-Atoll.dx6125023) - [Visit Bradford](https://expedia.co.uk/Bradford.dx4981) - [Visit Jujuy Province](https://expedia.co.uk/Jujuy-Province.dx6232492) - [Visit Paraná](https://expedia.co.uk/Parana.dx6052638) - [Visit Mato Grosso do Sul](https://expedia.co.uk/Mato-Grosso-Do-Sul.dx6052631) - [Visit Magallanes y Antartica Chilena](https://expedia.co.uk/Magallanes-Y-Antartica-Chilena.dx6236290) - [Visit Santa Catarina](https://expedia.co.uk/Santa-Catarina.dx6052646) - [Visit Rio Grande do Sul](https://expedia.co.uk/Rio-Grande-Do-Sul.dx6052643) ## Frequently asked questions ### How much do hotels in Santa Cruz cost? > The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from £11 in a few different ways on Expedia. First, key in the dates you'd like to go on holiday, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top. ### When is the best time to go to Santa Cruz? > If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately. ### Are there any luxury hotels in Santa Cruz? > Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as [Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information). Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at [Radisson Hotel Santa Cruz](https://www.expedia.co.uk/Santa-Cruz-Hotels-Radisson-Hotel-Santa-Cruz.h16447274.Hotel-Information). ### What are the top all-inclusive hotels in Santa Cruz? > If you're looking for a relaxed and worry-free escape, throw your bags down at [Prince Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Prince-Hotel.h16042447.Hotel-Information). Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz. ### How can I find cheap hotels in Santa Cruz? > Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our [cheap hotels in Santa Cruz](https://www.expedia.co.uk/Destinations-In-Santa-Cruz-Budget-Hotels.0-0-d6297178-tBudgetHotels.Hotel-Filter-Destinations) page. The lowest price available starts from £11 per night. ### What are the best hotels in Santa Cruz for families? > [Cosmopolitano Hotel Boutique](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cosmopolitano-Hotel-Boutique.h17512569.Hotel-Information) is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. [Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) is another favourite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveller experience" filter heading. ### Why should I book my Santa Cruz hotel with Expedia? > Unbeatable deals and plenty of options are just a couple of the reasons to book your Santa Cruz hotel with Expedia. Also, our rewards platform, One Key™, lets you collect and spend OneKeyCash™\* on eligible hotels, activities and more. And if your itinerary changes and you have to alter your booking, don't stress. Our online [Help Centre](https://www.expedia.co.uk/helpcenter) can assist you anytime, whether it's day or night. \*OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Expedia. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFUklEQVR4Xu3cQXIbOQxAUbq80DJH6KP4aOyj6Sg6wiy9cIljgCCBZrdTQU1lFvb/mygQyKddx8pkSvsfKuvgbwSSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVAH5KEtbH/1qTxuErZfW7mGrtn9sZ1b9ZhAQEJAeSK/6zSAguuvJcU2Pv42x37iOXsbvx2gGcjEC0S5vvBiBaJc3XoxAtMsbL0Yg2uWNFyMQ7fLGi9GfI3q8lFtHfPcuU1vciz/jW3vIL4bo6HhQAgEBkV9AQAoIiPV7pMmNv+SXex+V8tqRIs/4d5C+BtLfAQHRQAoISPlviI/0Rqt+Lo8vvaVXOQ0CAgLSAwEBySOe7Lb+QI/HLUXso2iKzEBAGgjI+gZIDwSkrcixre/q8fu48evRUvWbQS5GS9VvBrkYLVW/GeRitFT9ZpCL0VL1m0EuRkvVbwa5GC1VvzkgF7lrP2LrjaV/6a3J7/RH7N8FMgIJgSyBjEBCIEvfHrEb2/wRWwujxb187M9AQGIgICDVDsk5fxkD+VmI3ai7rT3k6b0X/cfFb7rcj9szft6oB+M/QdaDIZAGAqIHQUBAQHoB0ePW6fibLn+mrm/Ng6etEMjYmgdPWyGQsTUPnrZCIGNrHjxthUDG1jx42gqBjK158LQVAhlb8+BpK7Qitvt+eFQ/541z5D066AdBQCwQDwQERAMZnRHNdsv87tpGm2zJyNvkzT0M7K7ab5JAvE3e3MPA7qr9JgnE2+TNPQzsrtpvkkC8Td7cw8Duqv0mCcTb5M09DOyu2m+SQLxN3tzDwO6q/SYJxNvkzT0M7K7ab5IC4t37rj3QFbmXW1hwJGyV+YcDEBANBMQDAWkgXyD6ht7YZFd6laf38bG/uKVs/e04sq0ZCAhIfxsEBOQwArHmjcf0u2vt0aX4X4Hppyvl+A13kQ88AwFpICDHQEYgIO2IzN342N/kxjk69rQT6xwERAPRQECWQEA+ZMMf1f5GT5HpluNj/zhaAwEBOY/WQEBAzqO174scs6+ztVsbj31LP4qk34PH0SZ3Vb8ZpIDY4RAICIgEUkDkfX3Ga6095Jfa37zbdHVtKx6UdGsGooGAgIBIIBaIpYj1ebyUTUa12XfXdqMd95G2Hz6d3lXnmyAgIBoICAjI6IjUpn91fA+7pdjfOb/bHXNLk4+ixcf+GggISH8BAnIKBMQRu3HrI+tdXHvG243aNhae8g13E7eMPwlYICAgYwEEBAREJ/7SEO3m44Orx3e7/rBlXXw6EAsEZAQC4kOQ05b1o5A1vdF+xJblPrLuA4kHL1wQDWQNZAmkgYRdC2TpWyIXfXXc/iTg1T6Pro0kkKXa5yAzkAYCchnIT0DijdomU3vGx+NleewXuVF/EL+Po/4nAV3ylyASCIgGAiJL/hJE+plI9d81QXykx+0dc+eX3uW4JYEUEBAQkF7ckkAKyBmxH55vHWlyo/5fpPtyPz5HiuhHmd1k/pBX1Q7JOX8JAgICshcQOyTn/CUISEBaH735nvYMN6pr/7hYR3bXDAQEBAQEBCSFyHHtvf+I/dEXXo4/dVv3flCrPgYBAQmBgICAnBDPkNbdN0FkZMgY2fJe1NWPMg/OQEBAJBAQEJDRETm2yVSe8U+5UZZ91OyB3tpDVmvT/75Lk9+/2mub+EsQWQUBAQEZgbQfj/y9QFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZLq+yD/Ak5/UFV9SbZLAAAAAElFTkSuQmCC)