£326 Cheap Flights to Santa Cruz

View £326 flight on Wed, 16 Sept 2026Opens in a new window

Popular airlines to Santa Cruz

  • Avianca

  • LATAM Airlines Group

  • Boliviana De Aviacion

  • Copa

  • United

  • Iberia

  • GOL Linhas Aereas S.A.

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Cheap round-trip flights to Santa Cruz

Prices were available within the past 7 days and start at £326 for one-way flights and £632 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Sat, 6 Jun - Tue, 14 Jul
MAD
Madrid
VVI
Santa Cruz
£632 Return, found 1 day ago
£632
Return
found 1 day ago
Select Air Europa flight, departing Sat, 6 Jun from Madrid to Santa Cruz, returning Tue, 14 Jul, priced at £632 found 1 day ago
LATAM Airlines Group
Fri, 6 Nov - Wed, 11 Nov
MAD
Madrid
VVI
Santa Cruz
£642 Return, found 1 day ago
£642
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 6 Nov from Madrid to Santa Cruz, returning Wed, 11 Nov, priced at £642 found 1 day ago
Iberia
Sun, 25 Oct - Sun, 8 Nov
MAD
Madrid
VVI
Santa Cruz
£651 Return, found 5 days ago
£651
Return
found 5 days ago
Select Iberia flight, departing Sun, 25 Oct from Madrid to Santa Cruz, returning Sun, 8 Nov, priced at £651 found 5 days ago
avianca
Thu, 12 Nov - Mon, 16 Nov
MAD
Madrid
VVI
Santa Cruz
£652 Return, found 14 hours ago
£652
Return
found 14 hours ago
Select avianca flight, departing Thu, 12 Nov from Madrid to Santa Cruz, returning Mon, 16 Nov, priced at £652 found 14 hours ago
avianca
Thu, 24 Sept - Wed, 7 Oct
MAD
Madrid
VVI
Santa Cruz
£653 Return, found 5 days ago
£653
Return
found 5 days ago
Select avianca flight, departing Thu, 24 Sept from Madrid to Santa Cruz, returning Wed, 7 Oct, priced at £653 found 5 days ago
LATAM Airlines Group
Thu, 4 Feb - Thu, 11 Feb
MAD
Madrid
VVI
Santa Cruz
£654 Return, found 4 days ago
£654
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 4 Feb from Madrid to Santa Cruz, returning Thu, 11 Feb, priced at £654 found 4 days ago
Iberia
Fri, 12 Mar - Thu, 25 Mar
MAD
Madrid
VVI
Santa Cruz
£671 Return, found 9 hours ago
£671
Return
found 9 hours ago
Select Iberia flight, departing Fri, 12 Mar from Madrid to Santa Cruz, returning Thu, 25 Mar, priced at £671 found 9 hours ago
Iberia
Mon, 12 Oct - Sun, 29 Nov
MAD
Madrid
VVI
Santa Cruz
£672 Return, found 3 days ago
£672
Return
found 3 days ago
Select Iberia flight, departing Mon, 12 Oct from Madrid to Santa Cruz, returning Sun, 29 Nov, priced at £672 found 3 days ago
LATAM Airlines Group
Fri, 12 Mar - Thu, 25 Mar
MAD
Madrid
VVI
Santa Cruz
£672 Return, found 9 hours ago
£672
Return
found 9 hours ago
Select LATAM Airlines Group flight, departing Fri, 12 Mar from Madrid to Santa Cruz, returning Thu, 25 Mar, priced at £672 found 9 hours ago
Boliviana De Aviacion
Fri, 12 Mar - Thu, 25 Mar
MAD
Madrid
VVI
Santa Cruz
£681 Return, found 9 hours ago
£681
Return
found 9 hours ago
Select Boliviana De Aviacion flight, departing Fri, 12 Mar from Madrid to Santa Cruz, returning Thu, 25 Mar, priced at £681 found 9 hours ago

Trending flights to Santa Cruz

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Mon, 18 May - Tue, 9 Jun
LHR
London
VVI
Santa Cruz
£897 Return, found 3 hours ago
£897
Return
found 3 hours ago
Select KLM flight, departing Mon, 18 May from London to Santa Cruz, returning Tue, 9 Jun, priced at £897 found 3 hours ago

Frequently asked questions

How do I find cheap flights to Santa Cruz that have flexible change policies?
At Expedia, we've been channeling our inner acrobat to help you locate the most flexible airfares available. Just tick the "No change fee" box right underneath the "Flexible change policies" subheading to find your perfect flight to Santa Cruz.
Which airlines fly to Santa Cruz?
BoA runs flights into or near Santa Cruz, including 34 that fly into Viru Viru Intl. Airport (VVI) each month. Choose your holiday dates and then book your fare early for an unbeatable deal.
How can I find cheap tickets to Santa Cruz?
A helpful strategy for getting your hands on cheap airfares is to be flexible with your travel dates. Start by searching for your flight to Santa Cruz, then click on the "flexible dates" box to compare prices for nearby days. Want another tip? Book well ahead. To give you an idea of costs, £632 was the best price for a flight to Santa Cruz in the last seven days.
How much is a flight to Santa Cruz?
There were loads of bargain fares up for grabs in the last seven days, with the cost of a round-trip flight to Santa Cruz ranging between £632 and £897. Many lucky holiday makers nabbed one-way flights from Madrid (MAD) for as little as £326.
What are the most popular airports to fly into in Santa Cruz?
A major entryway to Santa Cruz, about 34 flights touch down at Viru Viru Intl. Airport (VVI) each month. Look for a top deal, book your seat and get set to soak up the best of this fantastic region.
When is the cheapest time to fly to Santa Cruz?
If you'd rather spend your holiday savings enjoying the best of Santa Cruz rather than on your flight there, take off early in the week. The cheapest day to fly is usually Tuesday, with Monday a close second. With many folks travelling on weekends, Saturday tends to have the highest ticket prices.
How much is a plane ticket to Santa Cruz?
In the last seven days, seats to Santa Cruz ranged between £632 and £897. Prices depend on multiple things, particularly the time of departure, airline, seating class and how early the fare is booked.
What is the best time to go to Santa Cruz?
Head for Santa Cruz during the busiest months of March, August and September. Tourists flock to renowned cities like Montero around this time. If you're fond of hot weather, it's worth noting that the summer season in Santa Cruz starts December 1. Average temperatures range from 21ºC to 32ºC in Montero then.
What months are the cheapest to book a flight to Santa Cruz?
Book your ticket in February for incredible flight deals to Santa Cruz. December is normally the most expensive time to purchase a seat.

Book with confidence

Top tips for booking flights to Santa Cruz from UK

Get ready to fly to Santa Cruz

Prepare your luggage and book your flights to Santa Cruz with Expedia. We offer a seamless flight booking experience, with a wide range of Santa Cruz plane tickets to choose from. If you need help finding some of the best deals for cheap flights to Santa Cruz in 2026, we are always available to assist you. Book your flights to Santa Cruz today and let the adventure begin!

Find the best tickets to Santa Cruz

To find some of the best tickets to Santa Cruz in 2026, use Expedia's powerful search engine to compare dates and the different departure and arrival airports for your trip. Whether you're after direct flights to Santa Cruz or last-minute flights to Santa Cruz, you can filter and sort your search results, making it easy to find the ideal flight to Santa Cruz.

Airlines fly to Santa Cruz

There are 20 different airlines that fly to Santa Cruz including some of the most trusted names in the business. To book flights to Santa Cruz with your favourite airline, take a look at Expedia's flight listings and try out different dates to find some of the best Santa Cruz plane tickets.

Find the cheapest flights to Santa Cruz

By booking early you may find some of the best deals for Santa Cruz flights from the UK, including Santa Cruz direct flights. You can usually find affordable and cheap flights to Santa Cruz, whether one-way from £326 or round-trip from £632, with Expedia if you book your trip far enough in advance.

Find the best airports for cheap flights to Santa Cruz

Try searching for different Santa Cruz airports with Expedia to find some of the cheapest flights to Santa Cruz. Flights from Madrid (MAD) to Santa Cruz (VVI) usually have the lowest price from £326.

Why book your flights to Santa Cruz with Expedia

Expedia offers great deals on Santa Cruz air fares from £326 to cater to every budget. Not only is Expedia one of the top platforms to book flights to Santa Cruz from the UK, it is also your one-stop shop for booking hotels, car rentals, and more.

 

*Prices and availability are subject to change. Additional terms apply.

Top tips for booking flights to Santa Cruz from UK

Travel information

Santa Cruz Flights Information

Airlines serving
avianca, Boliviana De Aviacion, LATAM Airlines Group, Air Europa, Iberia
Roundtrip price
from £632
Santa Cruz Flights Information

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