Title: Cheap Flights to Santa Cruz - Expedia.co.uk ![Lake Titicaca featuring general coastal views and a park](https://images.trvl-media.com/place/6053553/c22e3c92-bd89-4998-8279-debb63bcb80e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6053553/c22e3c92-bd89-4998-8279-debb63bcb80e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £90 Cheap Flights to Santa Cruz [View £90 flight on Sun, 19 Apr 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:GRU,to:VVI,departure:19/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:89.20&airProductToken=AQowCi4Ix2YSBDc2MzgYpqQBILVFKKvhigMw7uKKAzhCQABYAWoCTElyCEJORkNBRzJKEgoIARABGAEqAkczGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Santa Cruz Hotels](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations)[Santa Cruz Car Hire](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Car-Hire-Destinations)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6297178.Holidays-City-Breaks) ## Popular airlines to Santa Cruz - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group - ![Boliviana De Aviacion](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_OB.svg) Boliviana De Aviacion - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United - ![GOL Linhas Aereas S.A.](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_G3.svg) GOL Linhas Aereas S.A. - ![Air Europa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UX.svg) Air Europa - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap round-trip flights to Santa Cruz Prices were available within the past 7 days and start at £90 for one-way flights and £144 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![GOL Linhas Aereas S.A.](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/G3.gif) Mon, 13 Apr - Wed, 29 Apr GRU Sao Paulo VVI Santa Cruz £144 Return found 8 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:13/04/2026TANYT&leg2=from:VVI,to:GRU,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:143.10&airProductToken=AQowCi4Ix2YSBDc2MzgYpqQBILVFKPWdigMwrp-KAzhPQABYAWoCTElyCE9OT0tCRzJKCjAKLgjHZhIENzYzORi1RSCmpAEo4NOLAzCP1YsDOE9AAFgBagJMSXIIT05PS0JHMkoSCggBEAEYASoCRzMYASIECAEQASgCKAMoBDAB) ![GOL Linhas Aereas S.A.](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/G3.gif) Mon, 13 Apr - Wed, 29 Apr GRU Sao Paulo VVI Santa Cruz £203 Return found 8 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:13/04/2026TANYT&leg2=from:VVI,to:GRU,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:202.10&airProductToken=AQowCi4Ix2YSBDc2MzgYpqQBILVFKPWdigMwrp-KAzhPQABYAWoCQ0xyCE9OT0tCRzNKCjAKLgjHZhIENzYzORi1RSCmpAEo4NOLAzCP1YsDOE9AAFgBagJDTHIIT05PS0JHM0oSCggBEAEYASoCRzMYASIECAEQASgCKAMoBDAB) ![GOL Linhas Aereas S.A.](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/G3.gif) Thu, 11 Jun - Mon, 29 Jun GRU Sao Paulo VVI Santa Cruz £204 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:11/06/2026TANYT&leg2=from:VVI,to:GRU,departure:29/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:203.20&airProductToken=AQowCi4Ix2YSBDc2MzgYpqQBILVFKNW1jwMwjrePAzhPQABYAWoCQ0xyCE9OT0tCRzNKCjAKLgjHZhIENzYzORi1RSCmpAEogIKRAzCvg5EDOE9AAFgBagJDTHIIT05PS0JHM0oSCggBEAEYASoCRzMYASIECAEQASgCKAMoBDAB) ![GOL Linhas Aereas S.A.](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/G3.gif) Wed, 18 Mar - Wed, 25 Mar GRU Sao Paulo VVI Santa Cruz £208 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:18/03/2026TANYT&leg2=from:VVI,to:GRU,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:207.20&airProductToken=AQowCi4Ix2YSBDc3MTQYpqQBILVFKLX5hwMw6fqHAzhCQABYAWoCTElyCEJOQktCRzJKCjAKLgjHZhIENzcxNxi1RSCmpAEogMqIAzCvy4gDOEJAAFgBagJMSXIIQk5CS0JHMkoSCggBEAEYASoCRzMYASIECAEQASgCKAMoBDAB) ![GOL Linhas Aereas S.A.](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/G3.gif) Wed, 4 Mar - Tue, 10 Mar GRU Sao Paulo VVI Santa Cruz £221 Return found 20 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:04/03/2026TANYT&leg2=from:VVI,to:GRU,departure:10/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:220.10&airProductToken=AQowCi4Ix2YSBDc3MTQYpqQBILVFKPXbhgMwqd2GAzhOQABYAWoCTElyCE5OQUtBRzJKCjAKLgjHZhIENzcxNxi1RSCmpAEooKGHAzDPoocDOEJAAFgBagJMSXIIQk5GS0FHMkoSCggBEAEYASoCRzMYASIECAEQASgCKAMoBDAB) ![GOL Linhas Aereas S.A.](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/G3.gif) Mon, 16 Mar - Mon, 23 Mar GRU Sao Paulo VVI Santa Cruz £227 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:16/03/2026TANYT&leg2=from:VVI,to:GRU,departure:23/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:226.20&airProductToken=AQowCi4Ix2YSBDc3MTQYpqQBILVFKPXihwMwqeSHAzhCQABYAWoCTElyCEJOQktCRzJKCjAKLgjHZhIENzcxNxi1RSCmpAEowLOIAzDvtIgDOE5AAFgBagJMSXIITk5CQ0JHMkoSCggBEAEYASoCRzMYASIECAEQASgCKAMoBDAB) ![Boliviana De Aviacion](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/OB.gif) Fri, 13 Mar - Sun, 29 Mar GRU Sao Paulo VVI Santa Cruz £254 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:GRU,to:VVI,departure:13/03/2026TANYT&leg2=from:VVI,to:GRU,departure:29/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:253.10&airProductToken=AQoqCigIz4QBEgM3MzkYpqQBILVFKM_FhwMw-caHAzhTQABYAXIGU0lSV0VCCioKKAjPhAESAzczNBi1RSCmpAEo3_eIAzCJ-YgDOFNAAFgBcgZTSVJXRUISCggBEAEYASoCT0IYASIECAEQASgCKAQoBjAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, 15 Mar - Sun, 22 Mar MIA Miami VVI Santa Cruz £379 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MIA,to:VVI,departure:15/03/2026TANYT&leg2=from:VVI,to:MIA,departure:22/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:378.90&airProductToken=AQpmCjEIw5oBEgMxNzMYjAIg78QBKNnWhwMwktiHAzhUQABYAWoFQkFTSUNyCFRMQUFUWjJTCjEIw5oBEgMyMjEY78QBILVFKMPehwMw6uCHAzhUQAFYAWoFQkFTSUNyCFRMQUFUWjJTCmYKMQjDmgESAzEyNhi1RSDvxAEomqOIAzC8pYgDOFRAAFgBagVCQVNJQ3IIVExBQVRaMlMKMQjDmgESAzQzMhjvxAEgjAIoma2IAzDUrogDOFRAAVgBagVCQVNJQ3IIVExBQVRaMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Mon, 19 Jan - Sun, 25 Jan MIA Miami VVI Santa Cruz £408 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MIA,to:VVI,departure:19/01/2026TANYT&leg2=from:VVI,to:MIA,departure:25/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:407.70&airProductToken=AQpkCjAIwawBEgMxMjcYjAIgwTMo2O-CAzC58YIDOFNAAFgBagVCQVNJQ3IIU0VPQjBCUlMKMAjBrAESAzE2NxjBMyC1RSjW84IDMMv1ggM4U0ABWAFqBUJBU0lDcghTRU9CMEJSUwpiCjAIwawBEgMxNjYYtUUgwTMorK6DAzCXsIMDOFVAAFgBagVCQVNJQ3IIVVpPQjBJUjkKLgjBrAESATYYwTMgjAIo4rWDAzDSt4MDOFVAAVgBagVCQVNJQ3IIVVpPQjBJUjkSCggCEAEYAioCQVYYASIECAEQASgCKAMoBDAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Mon, 16 Mar - Mon, 23 Mar MIA Miami VVI Santa Cruz £424 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MIA,to:VVI,departure:16/03/2026TANYT&leg2=from:VVI,to:MIA,departure:23/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:423.90&airProductToken=AQpgCi4IzIIBEgQyNjk1GIwCIItiKMPnhwMwnOqHAzhOQABYAWoCU0xyCE5MRVNMRDhUCi4IzIIBEgQyNDA2GItiILVFKKjrhwMww-yHAzhOQAFYAWoCU0xyCE5MRVNMRDhUCmAKLgjMggESBDI0MDcYtUUgi2IotbCIAzDQsYgDOE5AAFgBagJTTHIITkxFU0xEOFQKLgjMggESBDI0ODAYi2IgjAIo27mIAzC-vIgDOE5AAVgBagJTTHIITkxFU0xEOFQSCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ## Top tips for booking flights to Santa Cruz from UK ### Get ready to fly to Santa Cruz Prepare your luggage and book your flights to Santa Cruz with Expedia. We offer a seamless flight booking experience, with a wide range of Santa Cruz plane tickets to choose from. If you need help finding some of the best deals for cheap flights to Santa Cruz in 2026, we are always available to assist you. Book your flights to Santa Cruz today and let the adventure begin! ### Find the best tickets to Santa Cruz To find some of the best tickets to Santa Cruz in 2026, use Expedia's powerful search engine to compare dates and the different departure and arrival airports for your trip. Whether you're after direct flights to Santa Cruz or last-minute flights to Santa Cruz, you can filter and sort your search results, making it easy to find the ideal flight to Santa Cruz. ### Airlines fly to Santa Cruz There are 20 different airlines that fly to Santa Cruz including some of the most trusted names in the business. To book flights to Santa Cruz with your favourite airline, take a look at Expedia's flight listings and try out different dates to find some of the best Santa Cruz plane tickets. ### Find the cheapest flights to Santa Cruz By booking early you may find some of the best deals for Santa Cruz flights from the UK, including Santa Cruz direct flights. You can usually find affordable and cheap flights to Santa Cruz, whether one-way from £90 or round-trip from £144, with Expedia if you book your trip far enough in advance. ### Find the best airports for cheap flights to Santa Cruz Try searching for different Santa Cruz airports with Expedia to find some of the cheapest flights to Santa Cruz. Flights from Sao Paulo (GRU) to Santa Cruz (VVI) usually have the lowest price from £90. ### Why book your flights to Santa Cruz with Expedia Expedia offers great deals on Santa Cruz air fares from £90 to cater to every budget. Not only is Expedia one of the top platforms to book flights to Santa Cruz from the UK, it is also your one-stop shop for booking hotels, car rentals, and more. \*Prices and availability are subject to change. Additional terms apply. ## Santa Cruz Flights Information | Airlines serving | GOL Linhas Aereas S.A., Boliviana De Aviacion, avianca, Aerolineas Argentinas, United, Copa, LATAM Airlines Group | | ---------------- | ----------------------------------------------------------------------------------------------------------------- | | Roundtrip price | from £144 | ## Frequently asked questions ### How do I find cheap flights to Santa Cruz that have flexible change policies? ### Which airlines fly to Santa Cruz? ### How can I find cheap tickets to Santa Cruz? ### How much is a flight to Santa Cruz? ### What are the most popular airports to fly into in Santa Cruz? ### When is the cheapest time to fly to Santa Cruz? ### How much is a plane ticket to Santa Cruz? ### What is the best time to go to Santa Cruz? ### What months are the cheapest to book a flight to Santa Cruz? - Top Flights Destinations - Top Santa Cruz Hotels - Related Airlines - Expedia's Latest Trends ### Top Flight Destinations In Santa Cruz - 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[Flights to Brazil ](https://expedia.co.uk/Destinations-In-Brazil.d23.Flight-Destinations) - [Flights to Germany ](https://expedia.co.uk/Destinations-In-Germany.d64.Flight-Destinations) - [Flights to Colombia ](https://expedia.co.uk/Destinations-In-Colombia.d38.Flight-Destinations) ### Top Santa Cruz Hotels - [Ibis Santa Cruz DE LA Sierra ](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) - [Camino Real Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) - [Marriott Santa Cruz de la Sierra Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) - [Hotel Las Américas ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Las-Americas.h112993678.Hotel-Information) - [Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) - [Sun Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) - [HOTEL OSHO ](https://expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) - [Hotel Cortez ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) - [Apart Hotel Premium Suites Santa Cruz ](https://expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) - [Chairú Eco Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) - [Premium Suites Deluxe Aparthotel Equipetrol ](https://expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) - [Swissôtel Santa Cruz De La Sierra ](https://expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) - [Lido Hotel ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) - [Hotel LP Santa Cruz Centro ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information) - [Hotel LP Equipetrol ](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Equipetrol.h10209582.Hotel-Information) - 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Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Wed, 11 Mar - Tue, 17 Mar LHR London VVI Santa Cruz £787 Return found 10 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LHR,to:VVI,departure:11/03/2026TANYT&leg2=from:VVI,to:LHR,departure:17/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:786.85&airProductToken=AQqcAQozCMuYARIEMTAwMBjriQEggJMBKIaohwMw1qiHAzhMQABYAWoFTElHSFRyCEdHTDZUSExBCjIIy5gBEgM3NTcYgJMBIO_EASjsqYcDMIqvhwM4R0ABWAFqBUxJR0hUcghHR0w2VEhMQQoxCMOaARIDMjIxGO_EASC1RSjDsYcDMOqzhwM4TEABWAFqBUxJR0hUcghHR0w2VEhMQQqYAQowCM-EARIDNzAwGLVFIKQmKLr0hwMw7vWHAzhPQABYAWoFTElHSFRyCFZHTDZUSExBCjAIwYwBEgM0MTEYpCYg4jAo5P-HAzDrhYgDOFZAAVgBagVMSUdIVHIIVkdMNlRITEEKMgjBjAESBDExODAY4jAg64kBKPyGiAMwzIeIAzhMQAFYAWoFTElHSFRyCFZHTDZUSExBEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwAQ) \*Available to Expedia members.