Title: The 10 Best 4 Star Hotels in Santa Cruz - 2026 Updated Prices | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.co.uk/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 4 Star hotels in Santa Cruz, Santa Cruz - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz 4 Star Hotels Tonight [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-01-09&endDate=2026-01-10&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-01-10&endDate=2026-01-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz 4-star hotels ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views ](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/01205665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/0ffe84ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camino Real Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) Santa Cruz 8.8/10 Excellent (410 reviews) "The parrots. Unique" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan P £134 10 Jan - 11 Jan [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/efaab5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/b93ef62e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/dcf17d3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/a8bc5939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) Santa Cruz 9.2/10 Wonderful (149 reviews) "The hotel is well located, convenient for restaurants and shopping, and very quiet. We stayed in a 2-bedroom suite, very well appointed and comfortable. Love the design of the corridor! Staff are friendly and helpful. A bar at the dining area where breakfast is would be great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vivian £74 18 Jan - 19 Jan [](https://www.expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/34d33eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/794bff22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/67ef04b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) Santa Cruz 9.2/10 Wonderful (259 reviews) "Nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Narciso Lorenzo £55 1 Feb - 2 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/6b27e04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/1b68b7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/9c172db1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/ffb227c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swissôtel Santa Cruz De La Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) Santa Cruz 9.2/10 Wonderful (82 reviews) "Beautiful hotel" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Joanna £94 24 Jan - 25 Jan [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/107000000/106730000/106727800/106727782/2c32b753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/107000000/106730000/106727800/106727782/7413122b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite | Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/107000000/106730000/106727800/106727782/943e942c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Single Room | Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/107000000/106730000/106727800/106727782/9177fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Maywa [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Maywa.h106727782.Hotel-Information) Santa Cruz 9.2/10 Wonderful (10 reviews) "The structure and service was fantastic" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Hotel-Maywa.h106727782.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/3dad56c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/4642408d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/4977a50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1160000/1156100/1156088/6fe3cece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buganvillas Hotel Suites & Spa [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Buganvillas-Hotel-Suites-Spa.h1156088.Hotel-Information) Santa Cruz 7.4/10 Good (93 reviews) "The correct description would be that it is a Air & B without a Stowe/owen/kitchen supplies but with a refrigerator. What they claim at the web page IS NOT correct. The pool is correct and there is a restaurant, a one man show. We were the only ones at breakfast, one day no one was even there. A scam. Majority are residents in this complex. The ladies at the receptions was sweet though and did their best. " ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Charlotte [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Buganvillas-Hotel-Suites-Spa.h1156088.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/16000000/15620000/15613500/15613409/fbee5fd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/16000000/15620000/15613500/15613409/53250319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/16000000/15620000/15613500/15613409/79f42889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/16000000/15620000/15613500/15613409/9b1e742b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Lodge Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Royal-Lodge-Hotel.h15613409.Hotel-Information) Santa Cruz 6.4/10 (29 reviews) "Esta cerrado, ya no deberia dejar reservar, se nota q tiene tiempo fuera de servicio." ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) Anonymous traveller [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Royal-Lodge-Hotel.h15613409.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Santa-Cruz-Hotels.s40-0-d6053940.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Santa-Cruz-Hotels.s40-0-d6053940.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz. ![Marriott Santa Cruz de la Sierra Hotel](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Marriott Santa Cruz de la Sierra Hotel 4to Anillo Entre Radial 23 Santa Cruz Santa Cruz £83 16 Jan - 17 Jan 9/10 Wonderful! (213 reviews) [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Novotel Santa Cruz De La Sierra](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/864143db_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Novotel Santa Cruz De La Sierra AV ROCA CORONADO 901 Santa Cruz £93 3 Feb - 4 Feb 9/10 Wonderful! (104 reviews) [](https://expedia.co.uk/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![Radisson Hotel Santa Cruz](https://images.trvl-media.com/lodging/17000000/16450000/16447300/16447274/c006f762_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Radisson Hotel Santa Cruz Avenida Segunda 4 Santa Cruz [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=16447274&PinnedHotelID=16447274&HadPinnedHotel=true®ionId=6053940) 8.6/10 Excellent! (237 reviews) [](https://expedia.co.uk/Santa-Cruz-Hotels-Radisson-Hotel-Santa-Cruz.h16447274.Hotel-Information) Still don't see what you're looking for? [See all properties in Santa Cruz.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6053940&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6053940&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6053940&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6053940&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6053940&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6053940&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Santa Cruz Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb. [See all hotels in Santa Cruz](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24&adults=2®ionId=6053940) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Santa Cruz Hotel Reviews ## Find out more about Santa Cruz ## Frequently asked questions ### What are the best 4-star hotels in Santa Cruz? ### How much does it cost to stay in a 4-star hotel in Santa Cruz? > - Search for the lowest price from £83 ### What's the difference between 5-star and 4-star hotels in Santa Cruz? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - [4 Star Hotels in Buena Vista ](https://www.expedia.co.uk/4Star-Buena-Vista-Hotels.s40-0-d3000445595.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Colinas del Urubo ](https://www.expedia.co.uk/5Star-Colinas-Del-Urubo-Hotels.s50-0-d6349680.Travel-Guide-Filter-Hotels) - [Colinas del Urubo Hotels ](https://www.expedia.co.uk/Colinas-Del-Urubo-Hotels.d6349680.Travel-Guide-Hotels) - 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[Flights from Altamira (ATM) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/atm/srz/altamira-to-santa-cruz) - [Flights from Alexandria (AXN) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/axn/srz/alexandria-to-santa-cruz) - [Flights from Hartford (BDL) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bdl/srz/hartford-to-santa-cruz) - [Flights from Bereina (BEA) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bea/srz/bereina-to-santa-cruz) - [Flights from Beirut (BEY) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bey/srz/beirut-to-santa-cruz) - [Flights from Belfast (BHD) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bhd/srz/belfast-to-santa-cruz) - [Flights from Bournemouth (BOH) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/boh/srz/bournemouth-to-santa-cruz) - [Flights from Boston (BOS) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bos/srz/boston-to-santa-cruz) - [Flights from Brussels (BRU) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bru/srz/brussels-to-santa-cruz) - [Flights from Bata (BSG) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bsg/srz/bata-to-santa-cruz) - [Flights from Buenos Aires (BUE) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/bue/srz/buenos-aires-to-santa-cruz) - [Flights from Bonito (BYO) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/byo/srz/bonito-to-santa-cruz) - [Flights from Cagliari (CAG) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cag/srz/cagliari-to-santa-cruz) - [Flights from Camiri (CAM) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cam/srz/camiri-to-santa-cruz) - [Flights from Guangzhou (CAN) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/can/srz/guangzhou-to-santa-cruz) - [Flights from Cochabamba (CBB) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cbb/srz/cochabamba-to-santa-cruz) - [Flights from Paris (CDG) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cdg/srz/paris-to-santa-cruz) - [Flights from Central (CEM) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cem/srz/central-to-santa-cruz) - [Flights from Cobija (CIJ) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cij/srz/cobija-to-santa-cruz) - [Flights from Charlotte (CLT) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/clt/srz/charlotte-to-santa-cruz) - [Flights from Ciudad Del Carmen (CME) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cme/srz/ciudad-del-carmen-to-santa-cruz) - [Flights from Copiapo (CPO) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/cpo/srz/copiapo-to-santa-cruz) - [Flights from Dhahran (DHA) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/dha/srz/dhahran-to-santa-cruz) - [Flights from The Dalles (DLS) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/dls/srz/the-dalles-to-santa-cruz) - [Flights from Derby (DRB) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/drb/srz/derby-to-santa-cruz) - [Flights from Dublin (DUB) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/dub/srz/dublin-to-santa-cruz) - [Flights from Dubai (DXB) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/dxb/srz/dubai-to-santa-cruz) - [Flights from Buenos Aires (EZE) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/eze/vvi/buenos-aires-to-santa-cruz) - [Flights from Flores (FRS) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/frs/srz/flores-to-santa-cruz) - [Flights from Gaya (GAY) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/gay/srz/gaya-to-santa-cruz) - [Flights from Rio de Janeiro (GIG) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/gig/srz/rio-de-janeiro-to-santa-cruz) - [Flights from Isla Baltra (GPS) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/gps/srz/isla-baltra-to-santa-cruz) - [Flights from São Paulo (GRU) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/gru/vvi/sao-paulo-to-santa-cruz) - [Flights from Gatokae (GTA) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/gta/srz/gatokae-to-santa-cruz) - [Flights from Guayaquil (GYE) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/gye/vvi/guayaquil-to-santa-cruz) - [Flights from Freetown (HGS) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/hgs/srz/freetown-to-santa-cruz) - [Flights from Frankfurt (HHN) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/hhn/srz/frankfurt-to-santa-cruz) - [Flights from Khajuraho (HJR) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/hjr/srz/khajuraho-to-santa-cruz) - [Flights from Takaka (KTF) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/ktf/srz/takaka-to-santa-cruz) - [Flights from Las Vegas (LAS) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/las/srz/las-vegas-to-santa-cruz) - [Flights from Los Angeles (LAX) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/lax/vvi/los-angeles-to-santa-cruz) - [Flights from London (LGW) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/lgw/vvi/london-to-santa-cruz) - [Flights from London (LHR) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/lhr/srz/london-to-santa-cruz) - [Flights from London (LHR) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/lhr/vvi/london-to-santa-cruz) - [Flights from Lima (LIM) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/lim/vvi/lima-to-santa-cruz) - [Flights from Ljubljana (LJU) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/lju/srz/ljubljana-to-santa-cruz) - [Flights from London (LON) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/lon/vvi/london-to-santa-cruz) - [Flights from La Paz (LPB) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/lpb/vvi/la-paz-to-santa-cruz) - [Flights from Madrid (MAD) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/mad/srz/madrid-to-santa-cruz) - [Flights from Madrid (MAD) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/mad/vvi/madrid-to-santa-cruz) - [Flights from Manchester (MAN) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/man/vvi/manchester-to-santa-cruz) - [Flights from Orlando (MCO) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/mco/srz/orlando-to-santa-cruz) - [Flights from Managua (MGA) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/mga/srz/managua-to-santa-cruz) - [Flights from Nuremberg (NUE) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/nue/srz/nuremberg-to-santa-cruz) - [Flights from Oakland (ODM) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/odm/srz/oakland-to-santa-cruz) - [Flights from Orlando (ORL) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/orl/srz/orlando-to-santa-cruz) - [Flights from Panama City (PAC) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/pac/srz/panama-city-to-santa-cruz) - [Flights from Punta Islita (PBP) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/pbp/srz/punta-islita-to-santa-cruz) - [Flights from Potosi (POI) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/poi/srz/potosi-to-santa-cruz) - [Flights from Panama City (PTY) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/pty/srz/panama-city-to-santa-cruz) - [Flights from Puerto Vallarta (PVR) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/pvr/srz/puerto-vallarta-to-santa-cruz) - [Flights from Dallas (RBD) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/rbd/srz/dallas-to-santa-cruz) - [Flights from Resende (REZ) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/rez/srz/resende-to-santa-cruz) - [Flights from Riberalta (RIB) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/rib/srz/riberalta-to-santa-cruz) - [Flights from San Diego (SAN) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/san/srz/san-diego-to-santa-cruz) - [Flights from Santa Ana del Yacuma (SBL) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/sbl/srz/santa-ana-del-yacuma-to-santa-cruz) - [Flights from Stockton (SCK) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/sck/srz/stockton-to-santa-cruz) - [Flights from Santiago (SCL) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/scl/srz/santiago-to-santa-cruz) - [Flights from San Francisco (SFO) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/sfo/srz/san-francisco-to-santa-cruz) - [Flights from San Francisco (SFO) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/sfo/vvi/san-francisco-to-santa-cruz) - [Flights from Springfield (SGF) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/sgf/srz/springfield-to-santa-cruz) - [Flights from San Juan (SJU) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/sju/srz/san-juan-to-santa-cruz) - [Flights from Salt Lake City (SLC) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/slc/srz/salt-lake-city-to-santa-cruz) - [Flights from Santa Maria (SMX) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/smx/srz/santa-maria-to-santa-cruz) - [Flights from Alcantarí Intl. Airport (SRE) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/sre/srz/sucre-to-santa-cruz) - [Flights from Sydney (SYD) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/syd/srz/sydney-to-santa-cruz) - [Flights from Trinidad (TDD) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/tdd/srz/trinidad-to-santa-cruz) - [Flights from Tarija (TJA) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/tja/srz/tarija-to-santa-cruz) - [Flights from Tsushima (TSJ) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/tsj/srz/tsushima-to-santa-cruz) - [Flights from Lake Tahoe (TVL) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/tvl/srz/lake-tahoe-to-santa-cruz) - [Flights from Ulaangom (ULO) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/ulo/srz/ulaangom-to-santa-cruz) - [Flights from Upolu Point (UPP) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/upp/srz/upolu-point-to-santa-cruz) - [Flights from Uyuni (UYU) to Santa Cruz (VVI) ](https://www.expedia.co.uk/lp/flights/uyu/vvi/uyuni-to-santa-cruz) - [Flights from Veracruz (VER) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/ver/srz/veracruz-to-santa-cruz) - [Flights from Van Nuys (VNY) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/vny/srz/van-nuys-to-santa-cruz) - [Flights from Mayo (YMA) to Santa Cruz (SRZ) ](https://www.expedia.co.uk/lp/flights/yma/srz/mayo-to-santa-cruz) - [Visit Colinas del Urubo ](https://www.expedia.co.uk/Colinas-Del-Urubo.dx6349680) - [Ethno-Folkloric Museum ](https://www.expedia.co.uk/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Attraction)