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Santa Cruz

Vacationers after the perfect mix of scenic, historical and cultural sights will love Santa Cruz.

Packages in Santa Cruz

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Our exhaustive database not only recommends 400 partner airlines and 321,000 worldwide hotels, but also features great discounts too.

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Do not worry about postponing your family's plans, as we do not charge additional cancellation fees for almost all of our hotel bookings.

Santa Cruz Vacation Packages

It is situated 13 miles northeast of La Guardia and about 340 miles east of La Paz, the national capital.

Don't forget to round up the kids and pay a visit to the Cine Center for an afternoon of fun and laughter.

The Santa Cruz Zoo is a terrific place to bring your family for a fun-filled day among local and exotic creatures. Be sure to ask at the entrance about hands-on activities and where to find the zoo's rarer species.

Guembe Biocenter plays a vital role in safeguarding the region's botanical specimens. Be sure to stop in and support the work that they do.

Take time off from the stresses of travel at one of the area's leafy public parks. Amboro National Park and Lomas de Arena Regional Park are lovely places to watch as the world passes on by. Arenal Park is another nice option.

Should the weather turn nasty, spend an hour or two at the Ethno-folkloric Museum or the Sacred Art Museum. Walk the halls at your leisure as you study the collections, or just savor a moment in one of the quiet spaces.

One of the more popular historic places in the area is the Franco Aleman Cultural Center. Educational and intriguing, it should definitely be on your itinerary.

Fascinated by different religions? Lose yourself in the contemplative atmosphere of San Lorenzo Cathedral and Catedral de Santa Cruz.

Public squares are great places to take the pulse of a city, and Plaza 24 de Septiembre is certainly no exception.

La Recova Artisan Walk is a busy retail area, packed with fashion, giftware and good places to eat.

Many travelers have a marvelous time at the Municipal Library. The Artecampo is also not to be forgotten.

Accommodation in Santa Cruz

There are 45 different Santa Cruz accommodation options listed on Expedia's lodging page. Have a browse and discover the best deal for you.

Why not start your search for the ultimate Santa Cruz room by checking out the amenities and rates of the excellent Buganvillas Hotel Suites & Spa, located at Av. Roca y Coronado No. 901, and the Los Tajibos Hotel And Convention Center, at Ave. San Martin, #455. If those don't exactly meet your needs, make sure you check out the Hostel Los Aventureros, at Cañada Strongest, 80, and the Loro Loco Hostel, at Av. Suarez Arana 134, two places where you'll be sure to find a bargain.


Top Hotel Deals

See all 88 Hotels in Santa Cruz
Marriott Santa Cruz de la Sierra
Marriott Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra

4to Anillo Entre Radial 23, Santa Cruz
     
    4.3
    of 5, from 6 reviews
    4.5 out of 5.0

    Situated in Santa Cruz, this hotel is close to Ventura Mall, Santa Cruz Zoo and Municipal Library. Also nearby are Arenal Park and Ethno-folkloric Museum.

    Radisson Hotel Santa Cruz
    Radisson Hotel Santa Cruz

    Radisson Hotel Santa Cruz

    Avenida Segunda 4, Santa Cruz
       
      4.7
      of 5, from 46 reviews
      4.0 out of 5.0

      Situated in Colinas del Urubo, this hotel is 2.8 mi (4.5 km) from Santa Cruz Zoo and within 6 miles (10 km) of Guembe Biocenter and Municipal Library. Arenal Park and La Recova Artisan Walk are also within 6 miles (10 km).

      Senses Boutique Hotel £59
      Senses Boutique Hotel

      Senses Boutique Hotel

      Calle 24 de Septiembre, Esq. Sucre No 5, Santa Cruz
         
        4.0
        of 5, from 148 reviews
        3.5 out of 5.0

        Located in the heart of Santa Cruz, this family-friendly hotel is steps away from San Lorenzo Cathedral, Franco Aleman Cultural Center and Sacred Art Museum. La Recova Artisan Walk and Guarani Nandereko Nomai Art and Culture Center are also within 5 minutes.

        Los Tajibos Hotel And Convention Center
        Los Tajibos Hotel And Convention Center

        Los Tajibos Hotel And Convention Center

        Ave. San Martin, #455, Santa Cruz
           
          4.3
          of 5, from 72 reviews
          4.5 out of 5.0

          Situated in Santa Cruz, this luxury hotel is within 2 miles (3 km) of Santa Cruz Zoo, Municipal Library and Arenal Park. Ethno-folkloric Museum and Guarani Nandereko Nomai Art and Culture Center are also within 2 miles (3 km).

          Camino Real Hotel £126
          Camino Real Hotel

          Camino Real Hotel

          Av. San Martín y 4to. Anillo, Santa Cruz
             
            4.2
            of 5, from 166 reviews
            4.0 out of 5.0

            This family-friendly Santa Cruz hotel is located near the airport, within 3 mi (5 km) of Santa Cruz Zoo, La Recova Artisan Walk and Artecampo. Municipal Library and Arenal Park are also within 3 miles (5 km).

            Hotel Las Palmas
            Hotel Las Palmas

            Hotel Las Palmas

            Av. El Trompillo, 604, Santa Cruz
               
              4.1
              of 5, from 34 reviews
              3.0 out of 5.0

              Located in the heart of Santa Cruz, this hotel is within a 15-minute walk of Cine Center and Blacutt Square. Ramon Tahuichi Aguilera Stadium and Artecampo are also within 1 mile (2 km).

              Apart Hotel Buen Retiro
              Apart Hotel Buen Retiro

              Apart Hotel Buen Retiro

              Calle Florida 432, Santa Cruz
                 
                4.7
                of 5, from 7 reviews
                2.5 out of 5.0

                Situated in Santa Cruz, this aparthotel is close to Guarani Nandereko Nomai Art and Culture Center, La Recova Artisan Walk and Plaza 24 de Septiembre. Also nearby are Franco Aleman Cultural Center and San Lorenzo Cathedral.

                La Quinta Apart Hotel £56
                La Quinta Apart Hotel

                La Quinta Apart Hotel

                Calle Aruma s/n, Barrio Urbari, Santa Cruz
                   
                  4.6
                  of 5, from 7 reviews
                  3.5 out of 5.0

                  Situated in Santa Cruz, this aparthotel is within 1 mile (2 km) of Ramon Tahuichi Aguilera Stadium and Artecampo. Cine Center and Blacutt Square are also within 2 miles (3 km).

                  Top Deals on Flights

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